Thrombolysis or peripheral arterial surgery: Phase I results

Journal of Vascular Surgery

Volumn 23, Issue 1, 1996, Pages 64-75

  Ouriel, K ^a   Veith, F J ^a   Sasahara, A A ^a   Whittemore, A D ^a   Roon, A J ^a   Braithwaite, B D ^a   Johnson, W C ^a   Porter, D H ^a   Burnand, K ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABT 120; ACETYLSALICYLIC ACID; RECOMBINANT UROKINASE; UNCLASSIFIED DRUG; UROKINASE;

ADULT; AGED; ARTERY BLOOD FLOW; BLOOD CLOT LYSIS; CLINICAL TRIAL; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FIBRINOLYTIC THERAPY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LIMB SALVAGE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS; VASCULAR SURGERY;

EID: 0030071788     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-5214(05)80036-9     Document Type: Conference Paper

References (21)

1. Blaisdell FW Steele M Allen RE Management of acute lower extremity arterial ischemia due to embolism and thrombosis Surgery 84 1978 822 834
2. Yeager RA Moneta GL Taylor LM Jr. Hamre DW McConnell DB Porter JM Surgical management of severe acute lower extremity ischemia J Vasc Surg 15 1992 385 393
3. Jivegard L Holm J Schersten T Acute limb ischemia due to arterial embolism or thrombosis: influence of limb ischemia versus pre-existing cardiac disease on postoperative mortality rate J Cardiovasc Surg (Torino) 29 1988 32 36
4. The STILE Investigators Results of a prospective randomized trial evaluating surgery versus thrombolysis for ischemia of the lower extremity: the STILE trial Ann Surg 220 1994 251 268
5. Hess H Ingrisch H Mietaschk A Rath H Local low-dose thrombolytic therapy of peripheral arterial occlusions N Engl J Med 307 1982 1627 1630
6. Sicard GA Schier JJ Totty WG Thrombolytic therapy for acute arterial occlusion J Vasc Surg 2 1985 65 78
7. McNamara TO Thrombolysis as an alternative initial therapy for the acutely ischemic lower limb Semin Vasc Surg 5 1992 89 98
8. Graor RA Olin J Bartholomew JR Ruschhaupt WF Young JR Efficacy and safety of intraarterial local infusion of steptokinase, urokinase, or tissue plasminogen activator for peripheral arterial occlusion: a retrospective review Journal of Vascular Medicine and Biology 2 1990 310 315
9. Abbott Laboratories Pharmaceutical Products Division Clinical protocol: recombinant urokinase (rUK, Abbott-76120) versus operative intervention as initial therapy for acute lower-limb arterial occlusion IND 4024 1993 M92 M859
10. Abbott Laboratories Pharmaceutical Products Division Clinical protocol: recombinant urokinase (rUK, Abbott-76120) versus operative intervention as initial therapy for acute lower-limb arterial occlusion IND 4024 1993 1 51
11. Rutherford RB Flanigan DP Gupta SK Suggested standards for reports dealing with lower extremity ischemia J Vasc Surg 4 1986 80 94
12. Tillett WS Johnson AJ McCarty WR The intravenous infusion of the streptococal fibrinolytic principle (Streptokinase) into patients J Clin Invest 34 1955 169 185
13. Cliffton EE Grossi CE Investigations of intravenous plasmin (fibrinolysin) in humans: physiologic and clinical effects [abstract] Circulation 14 1956 919
14. Cliffton EE The use of plasmin in humans Ann N Y Acad Sci 68 1957 209 229
15. Dotter CT Rösch J Seaman AJ Selective clot lysis with low-dose streptokinase Radiology 111 1974 31 37
16. Seabrook GR Mewissen MW Schmitt DD Percutaneous intraarterial thrombolysis in the treatment of thrombosis of lower extremity arterial reconstructions J Vasc Surg 13 1991 646 651
17. McNamara TO Fischer JR Thrombolysis of peripheral arterial and graft occlusions: improved results using high-dose urokinase AJR Am J Roentgenol 144 1985 769 775
18. Sullivan KL Gardiner GA Jr. Kandarpa K Efficacy of thrombolysis in infrainguinal bypass grafts Circulation 83 suppl I 1991 199
19. DeMaioribus CA Mills JL Fujitani RM A reevaluation of intraarterial thrombolytic therapy for acute lower extremity ischemia J Vasc Surg 17 1993 888 895
20. Nilsson L Albrechtsson U Jonung T Surgical treatment versus thrombolysis in acute arterial occlusion: a randomised controlled study Eur J Vasc Surg 6 1992 189 193
21. Ouriel K Shortell CK DeWeese JA A comparison of thrombolytic therapy with operative revascularization in the treament of acute peripheral arterial ischemia J Vasc Surg 19 1994 1021 1030