메뉴 건너뛰기




Volumn 200, Issue 1, 2011, Pages 29-38

Monoassociation with probiotic Lactobacillus delbrueckii UFV-H2b20 stimulates the immune system and protects germfree mice against Listeria monocytogenes infection

Author keywords

Cytokines; Immune system; Lactobacillus delbrueckii; Listeria monocytogenes; Probiotics

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; LACTOBACILLUS DELBRUECKII UFV H2B20; NITRIC OXIDE; PROBIOTIC AGENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 78751603852     PISSN: 03008584     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00430-010-0170-1     Document Type: Article
Times cited : (49)

References (36)
  • 2
    • 63849124042 scopus 로고    scopus 로고
    • Probiotics for preventive health
    • 10.1177/0884533608331177 19321897
    • A Minocha 2009 Probiotics for preventive health Nutr Clin Pract 24 227 241 10.1177/0884533608331177 19321897
    • (2009) Nutr Clin Pract , vol.24 , pp. 227-241
    • Minocha, A.1
  • 4
    • 31144447877 scopus 로고    scopus 로고
    • Partial characterization of ribosomal operons of Lactobacillus delbrueckii UFV H2b20
    • JTM Neves F Floresta CA Moraes 2005 Partial characterization of ribosomal operons of Lactobacillus delbrueckii UFV H2b20 J Microbiol 36 182
    • (2005) J Microbiol , vol.36 , pp. 182
    • Neves, J.T.M.1    Floresta, F.2    Moraes, C.A.3
  • 5
    • 0032241133 scopus 로고    scopus 로고
    • Monoassociation with Lactobacillus acidophilus UFV-H2b20 stimulates the immune defense mechanisms of germfree mice
    • 1:CAS:528:DyaK1MXhsVymsg%3D%3D 10.1590/S0100-879X1998001200009 9951553
    • E Neumann MA Oliveira CM Cabral LN Moura JR Nicoli EC Vieira DC Cara GI Podoprigora LQ Vieira 1998 Monoassociation with Lactobacillus acidophilus UFV-H2b20 stimulates the immune defense mechanisms of germfree mice Braz J Med Biol Res 31 1565 1573 1:CAS:528:DyaK1MXhsVymsg%3D%3D 10.1590/S0100- 879X1998001200009 9951553
    • (1998) Braz J Med Biol Res , vol.31 , pp. 1565-1573
    • Neumann, E.1    Oliveira, M.A.2    Cabral, C.M.3    Moura, L.N.4    Nicoli, J.R.5    Vieira, E.C.6    Cara, D.C.7    Podoprigora, G.I.8    Vieira, L.Q.9
  • 6
    • 0037073572 scopus 로고    scopus 로고
    • Microbes versus microbes: Immune signals generated by probiotic lactobacilli and their role in protection against microbial pathogens
    • 1:CAS:528:DC%2BD38Xoslans78%3D 10.1111/j.1574-695X.2002.tb00632.x 12443824
    • ML Cross 2002 Microbes versus microbes: immune signals generated by probiotic lactobacilli and their role in protection against microbial pathogens FEMS Immunol Med Microbiol 34 245 253 1:CAS:528:DC%2BD38Xoslans78%3D 10.1111/j.1574-695X.2002.tb00632.x 12443824
    • (2002) FEMS Immunol Med Microbiol , vol.34 , pp. 245-253
    • Cross, M.L.1
  • 7
    • 38049064390 scopus 로고    scopus 로고
    • Heat-killed cells of lactobacilli skew the immune response toward T helper 1 polarization in mouse splenocytes and dendritic cell-treated T cells
    • 1:CAS:528:DC%2BD2sXhtlGntrfE 10.1021/jf071786o 18038979
    • L Chuang KG Wu C Pai PS Hsieh JJ Tsai JH Yen MY Lin 2007 Heat-killed cells of lactobacilli skew the immune response toward T helper 1 polarization in mouse splenocytes and dendritic cell-treated T cells J Agric Food Chem 55 11080 11086 1:CAS:528:DC%2BD2sXhtlGntrfE 10.1021/jf071786o 18038979
    • (2007) J Agric Food Chem , vol.55 , pp. 11080-11086
    • Chuang, L.1    Wu, K.G.2    Pai, C.3    Hsieh, P.S.4    Tsai, J.J.5    Yen, J.H.6    Lin, M.Y.7
  • 8
    • 39749154743 scopus 로고    scopus 로고
    • Gut immune stimulation by non pathogenic Gram(+) and Gram(-) bacteria. Comparison with a probiotic strain
    • 1:CAS:528:DC%2BD1cXislSrtbo%3D 10.1016/j.cyto.2007.11.014 18248820
    • CA Dogi CM Galdeano G Perdigon 2008 Gut immune stimulation by non pathogenic Gram(+) and Gram(-) bacteria. Comparison with a probiotic strain Cytokine 41 223 231 1:CAS:528:DC%2BD1cXislSrtbo%3D 10.1016/j.cyto.2007.11.014 18248820
    • (2008) Cytokine , vol.41 , pp. 223-231
    • Dogi, C.A.1    Galdeano, C.M.2    Perdigon, G.3
  • 9
    • 34548512821 scopus 로고    scopus 로고
    • Human listeriosis and animal models
    • DOI 10.1016/j.micinf.2007.05.009, PII S1286457907001852, Forum on Listeria From Genomics to Pathagonesis
    • M Lecuit 2007 Human listeriosis and animal models Microbes Infect 9 1216 1225 1:CAS:528:DC%2BD2sXhtVCntrvF 10.1016/j.micinf.2007.05.009 17720601 (Pubitemid 47375149)
    • (2007) Microbes and Infection , vol.9 , Issue.10 , pp. 1216-1225
    • Lecuit, M.1
  • 10
    • 0028172004 scopus 로고
    • TNF-alpha and IFN-gamma stimulate a macrophage precursor cell line to kill Listeria monocytogenes in a nitric oxide-independent manner
    • 1:CAS:528:DyaK2MXit1GjsLg%3D 7525724
    • PJ Leenen BP Canono DA Drevets JS Voerman PA Campbell 1994 TNF-alpha and IFN-gamma stimulate a macrophage precursor cell line to kill Listeria monocytogenes in a nitric oxide-independent manner J Immunol 153 5141 5147 1:CAS:528:DyaK2MXit1GjsLg%3D 7525724
    • (1994) J Immunol , vol.153 , pp. 5141-5147
    • Leenen, P.J.1    Canono, B.P.2    Drevets, D.A.3    Voerman, J.S.4    Campbell, P.A.5
  • 11
    • 23744456814 scopus 로고    scopus 로고
    • Protection by Lactobacillus acidophilus UFV-H2b20 against experimental oral infection with Salmonella enterica subsp. i ser. Typhimurium in gnotobiotic and conventional mice
    • 10.1590/S1517-83822001000100015
    • LN Moura E Neumann LQ Vieira JR Nicoli 2001 Protection by Lactobacillus acidophilus UFV-H2b20 against experimental oral infection with Salmonella enterica subsp. I ser. Typhimurium in gnotobiotic and conventional mice Braz J Microbiol 32 66 69 10.1590/S1517-83822001000100015
    • (2001) Braz J Microbiol , vol.32 , pp. 66-69
    • Moura, L.N.1    Neumann, E.2    Vieira, L.Q.3    Nicoli, J.R.4
  • 12
    • 0002733180 scopus 로고
    • Gnotobiotics
    • E.C. Melby N.H. Altman (eds). CRC Press Cleveland
    • Pleasants JR (1974) Gnotobiotics. In: Melby EC, Altman NH (eds) Handbook of laboratory animal science. CRC Press, Cleveland, pp 119-174
    • (1974) Handbook of Laboratory Animal Science , pp. 119-174
    • Pleasants, J.R.1
  • 13
    • 0026781857 scopus 로고
    • Evaluation of nitrite production by human monocyte-derived macrophages
    • 1:CAS:528:DyaK38Xlt12rs7Y%3D 10.1016/0006-291X(92)90813-Z 1497665
    • EL Padgett SB Pruett 1992 Evaluation of nitrite production by human monocyte-derived macrophages Biochem Biophys Res Commun 186 775 781 1:CAS:528:DyaK38Xlt12rs7Y%3D 10.1016/0006-291X(92)90813-Z 1497665
    • (1992) Biochem Biophys Res Commun , vol.186 , pp. 775-781
    • Padgett, E.L.1    Pruett, S.B.2
  • 14
    • 17044456969 scopus 로고    scopus 로고
    • The human Lactobacillus acidophilus strain LA1 secretes a nonbacteriocin antibacterial substance(s) active in vitro and in vivo
    • 1:CAS:528:DyaK2sXktlertr4%3D 9212421
    • MF Bernet-Camard V Lievin D Brassart JR Neeser AL Servin S Hudault 1997 The human Lactobacillus acidophilus strain LA1 secretes a nonbacteriocin antibacterial substance(s) active in vitro and in vivo Appl Environ Microbiol 63 2747 2753 1:CAS:528:DyaK2sXktlertr4%3D 9212421
    • (1997) Appl Environ Microbiol , vol.63 , pp. 2747-2753
    • Bernet-Camard, M.F.1    Lievin, V.2    Brassart, D.3    Neeser, J.R.4    Servin, A.L.5    Hudault, S.6
  • 15
    • 36348954992 scopus 로고    scopus 로고
    • Protective effect of Lactobacillus sakei 2a against experimental challenge with Listeria monocytogenes in gnotobiotic mice
    • DOI 10.1111/j.1472-765X.2007.02250.x
    • FH Bambirra KG Lima BD Franco DC Cara RM Nardi FH Barbosa JR Nicoli 2007 Protective effect of Lactobacillus sakei 2a against experimental challenge with Listeria monocytogenes in gnotobiotic mice Lett Appl Microbiol 45 663 667 1:STN:280:DC%2BD2snpsV2ltQ%3D%3D 10.1111/j.1472-765X.2007.02250.x 17944842 (Pubitemid 350150790)
    • (2007) Letters in Applied Microbiology , vol.45 , Issue.6 , pp. 663-667
    • Bambirra, F.H.S.1    Lima, K.G.C.2    Franco, B.D.G.M.3    Cara, D.C.4    Nardi, R.M.D.5    Barbosa, F.H.F.6    Nicoli, J.R.7
  • 16
    • 0021324857 scopus 로고
    • Enhancement of host resistance against Listeria infection by Lactobacillus casei: Role of macrophages
    • 1:STN:280:DyaL2c7osVOisA%3D%3D 6425222
    • K Sato 1984 Enhancement of host resistance against Listeria infection by Lactobacillus casei: role of macrophages Infect Immun 44 445 451 1:STN:280:DyaL2c7osVOisA%3D%3D 6425222
    • (1984) Infect Immun , vol.44 , pp. 445-451
    • Sato, K.1
  • 17
    • 0037169910 scopus 로고    scopus 로고
    • Antagonistic activity of Lactobacillus casei strain Shirota against gastrointestinal Listeria monocytogenes infection in rats
    • DOI 10.1016/S0168-1605(01)00699-7, PII S0168160501006997
    • R de Waard J Garssen GC Bokken JG Vos 2002 Antagonistic activity of Lactobacillus casei strain shirota against gastrointestinal Listeria monocytogenes infection in rats Int J Food Microbiol 73 93 100 10.1016/S0168-1605(01)00699-7 11885574 (Pubitemid 34143089)
    • (2002) International Journal of Food Microbiology , vol.73 , Issue.1 , pp. 93-100
    • De Waard, R.1    Garssen, J.2    Bokken, G.C.A.M.3    Vos, J.G.4
  • 18
    • 0017845988 scopus 로고
    • Three phases of phagocyte contribution to resistance against Listeria monocytogenes
    • 1:STN:280:DyaE1c7ntlSitQ%3D%3D 418145
    • M Mitsuyama K Takeya K Nomoto S Shimotori 1978 Three phases of phagocyte contribution to resistance against Listeria monocytogenes J Gen Microbiol 106 165 171 1:STN:280:DyaE1c7ntlSitQ%3D%3D 418145
    • (1978) J Gen Microbiol , vol.106 , pp. 165-171
    • Mitsuyama, M.1    Takeya, K.2    Nomoto, K.3    Shimotori, S.4
  • 19
    • 0142093064 scopus 로고    scopus 로고
    • Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis
    • DOI 10.1189/jlb.0402212
    • V Veckman M Miettinen S Matikainen R Lande E Giacomini EM Coccia I Julkunen 2003 Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis J Leukoc Biol 74 395 402 1:CAS:528:DC%2BD3sXnsFKlsLw%3D 10.1189/jlb.0402212 12949243 (Pubitemid 38040400)
    • (2003) Journal of Leukocyte Biology , vol.74 , Issue.3 , pp. 395-402
    • Veckman, V.1    Miettinen, M.2    Matikainen, S.3    Lande, R.4    Giacomini, E.5    Coccia, E.M.6    Julkunen, I.7
  • 20
    • 19544385282 scopus 로고    scopus 로고
    • Immune responses that adapt the intestinal mucosa to commensal intestinal bacteria
    • DOI 10.1111/j.1365-2567.2005.02159.x
    • AJ Macpherson MB Geuking KD McCoy 2005 Immune responses that adapt the intestinal mucosa to commensal intestinal bacteria Immunology 115 153 162 1:CAS:528:DC%2BD2MXkslOgt7k%3D 10.1111/j.1365-2567.2005.02159.x 15885120 (Pubitemid 40733400)
    • (2005) Immunology , vol.115 , Issue.2 , pp. 153-162
    • Macpherson, A.J.1    Geuking, M.B.2    McCoy, K.D.3
  • 21
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • 1:CAS:528:DC%2BD1MXjvF2gtbk%3D 10.1038/nri2515 19343057
    • JL Round SK Mazmanian 2009 The gut microbiota shapes intestinal immune responses during health and disease Nat Rev Immunol 9 313 323 1:CAS:528:DC%2BD1MXjvF2gtbk%3D 10.1038/nri2515 19343057
    • (2009) Nat Rev Immunol , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 22
    • 16644399114 scopus 로고    scopus 로고
    • Macrophages in the small intestinal muscularis externa of embryos, newborn and adult germ-free mice
    • DOI 10.1023/B:HIJO.0000039840.86420.b7
    • HB Mikkelsen C Garbarsch J Tranum-Jensen L Thuneberg 2004 Macrophages in the small intestinal muscularis externa of embryos, newborn and adult germ-free mice J Mol Histol 35 377 387 1:CAS:528:DC%2BD2cXntFCntLk%3D 10.1023/B:HIJO. 0000039840.86420.b7 15503811 (Pubitemid 40576023)
    • (2004) Journal of Molecular Histology , vol.35 , Issue.4 , pp. 377-387
    • Mikkelsen, H.B.1    Garbarsch, C.2    Tranum-Jensen, J.3    Thuneberg, L.4
  • 23
    • 0030017334 scopus 로고    scopus 로고
    • Increased susceptibility to primary infection with Listeria monocytogenes in germfree mice may be due to lack of accumulation of L-selectin + CD44 + T cells in sites of inflammation
    • 1:CAS:528:DyaK28XksFGiurc%3D 8757865
    • H Inagaki T Suzuki K Nomoto Y Yoshikai 1996 Increased susceptibility to primary infection with Listeria monocytogenes in germfree mice may be due to lack of accumulation of L-selectin + CD44 + T cells in sites of inflammation Infect Immun 64 3280 3287 1:CAS:528:DyaK28XksFGiurc%3D 8757865
    • (1996) Infect Immun , vol.64 , pp. 3280-3287
    • Inagaki, H.1    Suzuki, T.2    Nomoto, K.3    Yoshikai, Y.4
  • 24
    • 34247513553 scopus 로고    scopus 로고
    • Prevention of pathogenic Escherichia coli infection in mice and stimulation of macrophage activation in rats by an oral administration of Probiotic Lactobacillus casei I-5
    • DOI 10.1271/bbb.60464
    • K Ishida-Fujii R Sato S Goto XP Yang H Kuboki S Hirano M Sato 2007 Prevention of pathogenic Escherichia coli infection in mice and stimulation of macrophage activation in rats by an oral administration of probiotic Lactobacillus casei I-5 Biosci Biotechnol Biochem 71 866 873 1:CAS:528:DC%2BD2sXltFCns7Y%3D 10.1271/bbb.60464 17420603 (Pubitemid 46650939)
    • (2007) Bioscience, Biotechnology and Biochemistry , vol.71 , Issue.4 , pp. 866-873
    • Ishida-Fujii, K.1    Sato, R.2    Goto, S.3    Yang, X.-P.4    Kuboki, H.5    Hirano, S.-I.6    Sato, M.7
  • 25
    • 34249790852 scopus 로고    scopus 로고
    • Lactobacillus delbrueckii as a potential skin adjuvant for induction of type 1 immune responses
    • DOI 10.2741/2148
    • LG Castanheira JM Castro OA Martins-Filho JR Nicoli LQ Vieira LC Afonso 2007 Lactobacillus delbrueckii as a potential skin adjuvant for induction of type 1 immune responses Front Biosci 12 1300 1307 1:CAS:528:DC%2BD28Xht1Wgsb%2FP 10.2741/2148 17127382 (Pubitemid 46846835)
    • (2007) Frontiers in Bioscience , vol.12 , Issue.4 , pp. 1300-1307
    • Castanheira, L.G.1    Castro, J.M.2    Martins-Filho, O.A.3    Nicoli, J.R.4    Vieira, L.Q.5    Afonso, L.C.C.6
  • 26
    • 65549141134 scopus 로고    scopus 로고
    • Lactobacillus delbrueckii UFV-H2b20 induces type 1 cytokine production by mouse cells in vitro and in vivo
    • 1:CAS:528:DC%2BD1MXls1yntrg%3D 10.1590/S0100-879X2009000400008 19330264
    • E Neumann MG Ramos LM Santos AC Rodrigues EC Vieira LC Afonso JR Nicoli LQ Vieira 2009 Lactobacillus delbrueckii UFV-H2b20 induces type 1 cytokine production by mouse cells in vitro and in vivo Braz J Med Biol Res 42 358 367 1:CAS:528:DC%2BD1MXls1yntrg%3D 10.1590/S0100-879X2009000400008 19330264
    • (2009) Braz J Med Biol Res , vol.42 , pp. 358-367
    • Neumann, E.1    Ramos, M.G.2    Santos, L.M.3    Rodrigues, A.C.4    Vieira, E.C.5    Afonso, L.C.6    Nicoli, J.R.7    Vieira, L.Q.8
  • 27
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • DOI 10.1016/j.cell.2004.07.002, PII S0092867404006610
    • S Rakoff-Nahoum J Paglino F Eslami-Varzaneh S Edberg R Medzhitov 2004 Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis Cell 118 229 241 1:CAS:528:DC%2BD2cXmtlKntrg%3D 10.1016/j.cell.2004.07.002 15260992 (Pubitemid 38962578)
    • (2004) Cell , vol.118 , Issue.2 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 29
    • 0029968783 scopus 로고    scopus 로고
    • Endogenous interleukin-4, but not interleukin-10, is involved in suppression of host resistance against Listeria monocytogenes infection in gamma interferon-depleted mice
    • A Nakane S Nishikawa S Sasaki T Miura M Asano M Kohanawa K Ishiwata T Minagawa 1996 Endogenous interleukin-4, but not interleukin-10, is involved in suppression of host resistance against Listeria monocytogenes infection in interferon-depleted mice Infect Immun 64 1252 1258 1:CAS:528:DyaK28XhvFSlu7o%3D 8606087 (Pubitemid 26102387)
    • (1996) Infection and Immunity , vol.64 , Issue.4 , pp. 1252-1258
    • Nakane, A.1    Nishikawa, S.2    Sasaki, S.3    Miura, T.4    Asano, M.5    Kohanawa, M.6    Ishiwata, K.7    Minagawa, T.8
  • 30
    • 0030608466 scopus 로고    scopus 로고
    • The protective role of endogenous cytokines in host resistance against an intragastric infection with Listeria monocytogenes in mice
    • DOI 10.1016/S0928-8244(96)00096-X, PII S092882449600096X
    • S Nishikawa T Miura S Sasaki A Nakane 1996 The protective role of endogenous cytokines in host resistance against an intragastric infection with Listeria monocytogenes in mice FEMS Immunol Med Microbiol 16 291 298 1:CAS:528:DyaK2sXhslSisw%3D%3D 10.1111/j.1574-695X.1996.tb00148.x 9116648 (Pubitemid 27041967)
    • (1996) FEMS Immunology and Medical Microbiology , vol.16 , Issue.3-4 , pp. 291-298
    • Nishikawa, S.1    Miura, T.2    Sasaki, S.3    Nakane, A.4
  • 31
    • 0033914375 scopus 로고    scopus 로고
    • Interleukin-10 has different effects on proliferation of Listeria monocytogenes in livers and spleens of mice
    • Samsom JN, Annema A, Geertsma MF, Langermans JA, Groeneveld PH, de HE, van FR (2000) Interleukin-10 has different effects on proliferation of Listeria monocytogenes in livers and spleens of mice. Infect Immun 68:4666-4672
    • (2000) Infect Immun , vol.68 , pp. 4666-4672
    • Samsom, J.N.1    Annema, A.2    Geertsma, M.F.3    Langermans, J.A.4    Groeneveld, P.H.5    De, H.6    Van, F.R.7
  • 32
    • 0036883901 scopus 로고    scopus 로고
    • Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
    • 1:CAS:528:DC%2BD38Xpt1Kmtbg%3D 12444113
    • Y Cong CT Weaver A Lazenby CO Elson 2002 Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora J Immunol 169 6112 6119 1:CAS:528:DC%2BD38Xpt1Kmtbg%3D 12444113
    • (2002) J Immunol , vol.169 , pp. 6112-6119
    • Cong, Y.1    Weaver, C.T.2    Lazenby, A.3    Elson, C.O.4
  • 33
    • 77749322389 scopus 로고    scopus 로고
    • A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells
    • 10.1371/journal.pone.0009009 20126401
    • S Lavasani B Dzhambazov M Nouri F Fak S Buske G Molin H Thorlacius J Alenfall B Jeppsson B Westrom 2010 A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells PLoS One 5 e9009 10.1371/journal.pone.0009009 20126401
    • (2010) PLoS One , vol.5 , pp. 9009
    • Lavasani, S.1    Dzhambazov, B.2    Nouri, M.3    Fak, F.4    Buske, S.5    Molin, G.6    Thorlacius, H.7    Alenfall, J.8    Jeppsson, B.9    Westrom, B.10
  • 35
    • 0037033376 scopus 로고    scopus 로고
    • + T cells activated in cutaneous or mucosal lymphoid tissues
    • DOI 10.1084/jem.20011502
    • DJ Campbell EC Butcher 2002 Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues J Exp Med 195 135 141 1:CAS:528:DC%2BD38XjslOjug%3D%3D 10.1084/jem.20011502 11781372 (Pubitemid 34074503)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.1 , pp. 135-141
    • Campbell, D.J.1    Butcher, E.C.2
  • 36
    • 33644549184 scopus 로고    scopus 로고
    • Enteric flora in health and disease
    • 10.1159/000089775 16498248
    • F Guarner 2006 Enteric flora in health and disease Digestion 73 Suppl 1 5 12 10.1159/000089775 16498248
    • (2006) Digestion , vol.73 , Issue.SUPPL. 1 , pp. 5-12
    • Guarner, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.