Design, development and bioavailability assessment of oxytetracycline hydrochloride double o/w/o microemulsion formulation

Journal of Drug Delivery Science and Technology

Volumn 18, Issue 6, 2008, Pages 404-409

  Serdoz, F ^a   Voinovich, D ^a   Perissutti, B ^a   Magarotto, L ^a   Carli, F ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Double microemulsion; DSC; Oral bioavailability; Oxytetracycline hydrochloride; Pharmacokinetics; Ternary phase diagram

Indexed keywords

OXYTETRACYCLINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG DETERMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG SOLUBILITY; MALE; MAXIMUM PLASMA CONCENTRATION; MICROEMULSION; NONHUMAN; PHYSICAL CHEMISTRY; PROCESS TECHNOLOGY; RAT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; ZETA POTENTIAL;

EID: 57749180134     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(08)50079-7     Document Type: Article

References (18)

1. Mc Evoy E., Donegan S., Power J., Altria K. - Optimisation and validation of a rapid and efficient microemulsion liquid chromatographic (MELC) method for the determination of paracetamol (acetaminophen) content in a suppository formulation. - J. Pharm. Biomed. Anal., 44, 137-143, 2007.
2. Shah N.H., Carvajal M.T., Patel C.I., Infeld M.H., Malick A.W. - Self-emulsifying drug delivery system (SEDDS) with polyglycolised glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. - Int. J. Pharm., 106, 15-23, 1994.
3. Ghosh RK., Majithiya R.J., Umrethia M.L., Murthy R.S.R. - Design and development of microemulsion drug delivery system of acyclovir for improvement of oral bioavailability. - AAPS PharmSciTech., 7 (3), article 77 (http://www.aapspharmscitech.org), 2006.
4. Cournarie F., Savelli M., Rosilio V., Bretez F., Vauthier C., Grossiord J., Seiller M. - Insulin-loaded w/o/w multiple emulsions: comparison of the performances of systems prepared with medium-chain-tryglicerides and fish oil. - Eur. J. Pharm. Biopharm., 58, 477-482, 2004.
5. Florence A.T., Atwood D. (Eds.) - Physicochemical Principles of Pharmacy. - 3rd ed., Macmillan Press, London, 2003.
6. Lawrence M.J., Rees G.D.- Microemulsion-based media as novel drug delivery systems. - Adv. Drug Del. Rev., 45, 89-121, 2000.
7. Gupta S., Moulik S.P. - Biocompatible microemulsions and their prospective uses in drug delivery. - J. Pharm. Sci., 97, 22-45, 2008.
8. Schaftenaar W., Prenen G.H., Seinhorst J.W., Jager L.P.- Oxytetracycline and oral herd treatment: a literature review. - Tijdschrift voor diergeneeskunde, 115, 825-836, 1990.
9. Elema M.O., Hoff K.A., Kristensen H.G. - Bioavailability of oxytetracycline from medicated feed administered to Atlantic salmon ( Salmo salar L.)in seawater. - Aquaculture, 43, 7-14, 1996.
10. Ali S.L. - Tetracycline hydrochloride. - In: Analytical Profiles of Drug Substances, K. Florey Ed., Academic Press, Orlando, 1984, Vol. 13, pp. 597-653.
11. Mackay R.A. - Use of triangular diagrams in the study of emulsions. - In: Encyclopedia of Emulsion Technology, Becher P. Ed., Marcel Dekker, New York, 1988, Vol. 3, pp. 233-237.
12. Senatra D., Lendinara L., Giri M.G. - W/O microemulsions as model systems for the study of water confined in microenvironments: low resolution 1H magnetic resonance relaxation analysis. - Prog. Coll. Polym, Sci., 84, 122, 1991.
13. Shafiq, S., Shakeel, F., Talegaonkar, S., Ahmad, F.J., Khar, R.K., Ali M. - Development and bioavailability assessment of ramipril nanoemulsion formulation. - Eur. J. Pharm. Biopharm., 66, 227-243, 2007.
14. Constantinides P.P., Scalart J.P. - Formulation and physical characterisation of water-in-oil microemulsion containing long- versus medium-chain glycerides. - Int. J. Pharm., 158, 57-68, 1997.
15. Verwey E.W., Overbeek J.Th.G. (Eds.) - Theory of the Stability of Liophobic Colloids. - Elsevier, Amsterdam, 1948.
16. Ma Q.H., Xia Q., Lu Y.Y., Hao X.Z., Gu N., Lin X.F., Luo D. - Preparation of tea polyphenols-loaded solid lipid nanoparticles based on the phase behaviours of hot microemulsions. - Solid State Phenomena, 121-123, 705-708, 2007.
17. Wang S., Sun M., Ping Q. - Enhancing effect of Labrafac Lipophile WL 1349 on oral bioavailability of hydroxysafflor yellow A in rats. - Int. J. Pharm., 358, 198-204, 2008.
18. Aungst B.J. - Intestinal permeation enhancers. - J. Pharm. Sci., 89, 429-441 2000.