Mycoplasma hyopneumoniae induces pro-inflammatory cytokine and nitric oxide production through NFκB and MAPK pathways in RAW264.7 cells

Veterinary Research Communications

Volumn 35, Issue 1, 2011, Pages 21-34

  Hwang, Mi Hyun ^a   Damte, Dereje ^a   Lee, Joong Su ^a   Gebru, Elias ^a   Chang, Zhi Qiang ^a,d   Cheng, Henrique ^b   Jung, Byeong Yeal ^c   Rhee, Man Hee ^a   Park, Seung Chun ^a  

^a Kyungpook National University   (South Korea)

^b LOUISIANA STATE UNIVERSITY   (United States)

^c Animal Plant and Fisheries Quarantine and Inspection Agency   (South Korea)

^d YELLOW SEA FISHERIES RESEARCH INSTITUTE   (China)

Author keywords

MAPK; Mycoplasma hyopneumoniae; NF B; RAW264.7 cells

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PYRROLIDINE DITHIOCARBAMATE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BACTERIAL METABOLISM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; HOST PATHOGEN INTERACTION; IMMUNOREACTIVITY; INFLAMMATION; MACROPHAGE; MYCOPLASMA HYOPNEUMONIAE; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BUTADIENES; CELL LINE; CYTOKINES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; IMIDAZOLES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MYCOPLASMA HYOPNEUMONIAE; NF-KAPPA B; NITRIC OXIDE; NITRILES; PHOSPHORYLATION; PNEUMONIA OF SWINE, MYCOPLASMAL; PROTEIN KINASE INHIBITORS; PYRIDINES; PYRROLIDINES; SWINE; THIOCARBAMATES;

MURINAE; MYCOPLASMA HYOPNEUMONIAE;

EID: 78751575871     PISSN: 01657380     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11259-010-9447-5     Document Type: Article

References (33)

1. SF Amass LK Clark WG van Alstine TL Bowersock DA Murphy KE Knox SR Albregts 1994 Interaction of Mycoplasma hyopneumoniae and Pasteurella multocida infections in swine J Am Vet Med Assoc 204 102 107 1:STN:280: DyaK2c7ntFGrtg%3D%3D 8125807
2. T Asai M Okada M Ono T Irisawa Y Mori Y Yokomizo S Sato 1993 Increased levels of tumor necrosis factor and interleukin 1 in bronchoalveolar lavage fluids from pigs infected with Mycoplasma hyopneumoniae Vet Immunol Immunopathol 38 253 260 1:CAS:528:DyaK2cXhtVCrsLk%3D 10.1016/0165-2427(93)90085-I 8291203
3. T Asai M Okada M Ono Y Mori Y Yokomizo S Sato 1994 Detection of interleukin-6 and prostaglandin E2 in bronchoalveolar lavage fluids of pigs experimentally infected with Mycoplasma hyponeumoniae Vet Immunol Immunopathol 44 97 102 1:CAS:528:DyaK2MXks1Sqs7g%3D 10.1016/0165-2427(94)90172-4 7725632
4. PA Baeuerle T Henkel 1994 Function and activation of NF-kappa B in the immune system Annu Rev Immunol 12 141 179 1:CAS:528:DyaK2cXivFKjurY%3D 8011280
5. C Choi D Kwon K Jung Y Ha YH Lee O Kim HK Park SH Kim KK Hwang C Chae 2006 Expression of inflammatory cytokines in pigs experimentally infected with Mycoplasma hyopneumoniae J Comp Pathol 134 40 46 1:CAS:528: DC%2BD28XmsFSntw%3D%3D 10.1016/j.jcpa.2005.06.009 16325841
6. MA Collart P Baeuerle P Vassalli 1990 Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B Mol Cell Biol 10 1498 1506 1:CAS:528:DyaK3cXhslKktb0%3D 2181276
7. MC DeBey RF Ross 1994 Ciliostasis and loss of cilia induced by Mycoplasma hyopneumoniae in porcine tracheal organ cultures Infect Immun 62 5312 5318 1:CAS:528:DyaK2MXitlShtr4%3D 7960110
8. M Digicaylioglu S Lipton 2001 Erthropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-κB signalling cascades Nature 412 641 647 1:CAS:528:DC%2BD3MXmtVCisbs%3D 10.1038/35088074 11493922 (Pubitemid 32772276)
9. SH Feng SC Lo 1999 Lipid extract of Mycoplasma penetrans proteinase K-digested lipid-associated membrane proteins rapidly activates NF-kappaB and activator protein 1 Infect Immun 67 2951 1256 1:CAS:528:DyaK1MXjsFSnsrg%3D 10338504
10. NF Friis J Szancer 1994 Sensitivity of certain porcine and bovine mycoplasmas to antimicrobial agents in a liquid medium test compared to a disc assay Acta Vet Scand 35 389 394 1:STN:280:DyaK2Mvgslequg%3D%3D 7676922
11. J Garcia B Lemercier S Roman-Roman G Rawadi 1998 A Mycoplasma fermentans-derived synthetic lipopeptide induces AP-1 and NF-kappaB activity and cytokine secretion in macrophages via the activation of mitogen-activated protein kinase pathways J Biol Chem 273 34391 34398 1:CAS:528:DyaK1MXntlam 10.1074/jbc.273.51.34391 9852105 (Pubitemid 29008917)
12. S Grimm PA Baeuerle 1993 The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits Biochem J 290 Part 2 297 308 1:CAS:528:DyaK3sXhvVCntL8%3D 8452515
13. MH Hwang JH Lim HI Yun JC Kim BY Jung WH Hsu SC Park 2006 The effect of polyclonal antibody on intracellular calcium increase induced by Mycoplasma hyopneumoniae in porcine tracheal cells Vet J 172 556 560 1:CAS:528: DC%2BD28XhtFSktLrK 10.1016/j.tvjl.2005.05.015 16051507 (Pubitemid 44575913)
14. MH Hwang ZQ Chang EH Kang JH Lim HI Yun MH Rhee KS Jeong SC Park 2008 Surfactin C inhibits Mycoplasma hyopneumoniae-induced transcription of proinflammatory cytokines and nitric oxide production in murine RAW 264.7 cells Biotechnol Lett 30 229 233 1:CAS:528:DC%2BD2sXhsVKrtrjP 10.1007/s10529-007-9552- x 17928958
15. CV Jongeneel 1994 Regulation of the TNF alpha gene Prog Clin Biol Res 388 367 381 1:CAS:528:DyaK2cXmslyhsrY%3D 7831369
16. Y Lim H Seok 2002 Studies on the mycoplasmal pneumoniae in slaughter pigs. 1. Seasonal detection by gross finding of lung lesion and dot-ELISA technique Korean J Vet Res 42 219 224
17. CJ Lowenstein EW Alley P Raval AM Snowman SH Snyder SW Russell WJ Murphy 1993 Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide Proc Natl Acad Sci USA 90 9730 9734 1:CAS:528:DyaK2cXitVyk 10.1073/pnas.90.20.9730 7692452 (Pubitemid 23315860)
18. D Maes J Segales T Meyns M Sibila M Pieters F Haesebrouck 2008 Control of Mycoplasma hyopneumoniae infections in pigs Vet Microbiol 126 297 309 1:CAS:528:DC%2BD2sXhsVWjtL7E 10.1016/j.vetmic.2007.09.008 17964089 (Pubitemid 350192091)
19. JM Muller HW Ziegler-Heitbrock PA Baeuerle 1993 Nuclear factor kappa B, a mediator of lipopolysaccharide effects Immunobiology 187 233 256 1:STN:280:DyaK3szit1Srsg%3D%3D 8330898
20. Y Muneta H Uenishi R Kikuma K Yoshihara Y Shimoji R Yamamoto N Hamashima Y Yokomizo Y Mori 2003 Porcine TLR2 and TLR6: identification and Their Involvement in Mycoplasma hyopneumoniae Infection J Interferon Cytokine Res 23 583 590 1:CAS:528:DC%2BD3sXot1anurw%3D 10.1089/107999003322485080 14585198 (Pubitemid 37323680)
21. G Rawadi V Ramez B Lemercier S Roman-Roman 1998 Activation of mitogen-activated protein kinase pathways by Mycoplasma fermentans membrane lipoproteins in murine macrophages: involvement in cytokine synthesis J Immunol 160 1330 1339 1:CAS:528:DyaK1cXns1Oguw%3D%3D 9570551 (Pubitemid 28093432)
22. G Rawadi J Garcia B Lemercier S Roman-Roman 1999 Signal transduction pathways involved in the activation of NF-kappa B, AP-1, and c-fos by Mycoplasma fermentans membrane lipoproteins in macrophages J Immunol 162 2193 2203 1:CAS:528:DyaK1MXhtVOmtrc%3D 9973495
23. G Sacht A Marten U Deiters R Sussmuth G Jung E Wingender PF Muhlradt 1998 Activation of nuclear factor-kappaB in macrophages by mycoplasmal lipopeptides Eur J Immunol 28 4207 4212 1:CAS:528:DyaK1cXotVSmt70%3D 10.1002/(SICI)1521- 4141(199812)28:12<4207::AID-IMMU4207>3.0.CO;2-R 9862357
24. JS Sanghera SL Weinstein M Aluwalia J Girn SL Pelech 1996 Activation of multiple proline-directed kinases by bacterial lipopolysaccharide in murine macrophages J Immunol 156 4457 4465 1:CAS:528:DyaK28XjtFCms7w%3D 8666821
25. MH Sohn KE Lee SY Choi BC Kwon MW Chang KE Kim 2005 Effect of Mycoplasma pneumoniae lysate on interleukin-8 gene expression in human respiratory epithelial cells Chest 128 322 326 1:CAS:528:DC%2BD2MXnvFyqt7w%3D 10.1378/chest.128.1.322 16002953 (Pubitemid 40994491)
26. I Stancovski D Baltimore 1997 NF-kappaB activation: the I kappaB kinase revealed? Cell 91 299 302 1:CAS:528:DyaK2sXnt1ClsrY%3D 10.1016/S0092-8674(00) 80413-4 9363938 (Pubitemid 27467960)
27. B Su M Karin 1996 Mitogen-activated protein kinase cascades and regulation of gene expression Curr Opin Immunol 8 402 411 1:CAS:528: DyaK28XktlegtL4%3D 10.1016/S0952-7915(96)80131-2 8793994 (Pubitemid 26229663)
28. EL Thacker BJ Thacker M Kuhn PA Hawkins WR Waters 2000 Evaluation of local and systemic immune responses induced by intramuscular injection of a Mycoplasma hyopneumoniae bacterin to pigs Am J Vet Res 61 1384 1389 1:STN:280:DC%2BD3M7lvFCgsw%3D%3D 10.2460/ajvr.2000.61.1384 11108184
29. R Thanawongnuwech TF Young BJ Thacker EL Thacker 2001 Differential production of proinflammatory cytokines: in vitro PRRSV and Mycoplasma hyopneumoniae co-infection model Vet Immunol Immunopathol 79 115 127 1:CAS:528:DC%2BD3MXjsFalt7w%3D 10.1016/S0165-2427(01)00243-4 11356254 (Pubitemid 32463327)
30. R Thanawongnuwech B Thacker P Halbur EL Thacker 2004 Increased production of proinflammatory cytokines following infection with porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae Clin Diagn Lab Immunol 11 901 908 1:CAS:528:DC%2BD2cXptVOnu7g%3D 15358650
31. ST Whiteside A Israel 1997 I kappa B proteins: structure, function and regulation Semin Cancer Biol 8 75 82 1:CAS:528:DyaK2sXmtlGqsb0%3D 10.1006/scbi.1997.0058 9299585 (Pubitemid 27412323)
32. SH Yang AD Sharrocks AJ Whitmarsh 2003 Transcriptional regulation by the MAP kinase signaling cascades Gene 320 13 21 10.1016/S0378-1119(03)00816-3 (Pubitemid 37352751)
33. X You Wu Yimou Y Zeng Z Deng H Qiu Yu Minjun 2008 Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kB andAP-1 in THP-1cells FEMS Immunol Med Microbiol 52 228 236 1:CAS:528:DC%2BD1cXjt1CmsL4%3D 10.1111/j.1574-695X.2007.00366.x 18177344 (Pubitemid 351248429)