Mitogen-activated protein kinases ERK 1/2- and p38-GATA4 pathways mediate the Ang II-induced activation of FGF2 gene in neonatal rat cardiomyocytes

Biochemical Pharmacology

Volumn 81, Issue 4, 2011, Pages 518-525

  Tang, Wenjie ^a,b   Wei, Youzhen ^c   Le, Kang ^a   Li, Zhi ^d   Bao, Yingxia ^a   Gao, Jie ^a   Zhang, Fangyan ^a   Cheng, Shaorui ^a   Liu, Peiqing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^d TONGJI UNIVERSITY   (China)

Author keywords

Cardiac hypertrophy; FGF2; GATA4; Promoter; Transcription factor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN II; FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR GATA 4;

ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING MOTIF; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION; HEART MUSCLE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UPREGULATION; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; DNA; FIBROBLAST GROWTH FACTOR 2; GATA4 TRANSCRIPTION FACTOR; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 78751569887     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.11.012     Document Type: Article

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