Endothelin ETB receptor is involved in sex differences in the development of balloon injury-induced neointimal formation

Journal of Pharmacology and Experimental Therapeutics

Volumn 336, Issue 2, 2011, Pages 533-539

  Kitada, Kento ^a   Yui, Nozomi ^a   Koyama, Maki ^a   Kimura, Kimihiro ^a   Suzuki, Rie ^a   Tanaka, Ryosuke ^a   Mori, Tatsuhiko ^a   Ohkita, Mamoru ^a   Matsumura, Yasuo ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 BUTYL 7 [2 (2 CARBOXYPROPYL) 4 METHOXYPHENYL] 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE 6 CARBOXYLIC ACID; 4 (1,3 BENZODIOXOL 5 YL) 1 [(2,6 DIETHYLPHENYL)CARBAMOYLMETHYL] 2 (4 PROPOXYPHENYL) 3 PYRROLIDINECARBOXYLIC ACID; ATRASENTAN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ESTRADIOL; ESTROGEN; MESSENGER RNA; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CAROTID ARTERY INJURY; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIN B RECEPTOR DEFICIENCY; ESTROGEN DEFICIENCY; FEMALE; MALE; NEOINTIMA; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; RAT; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; UTERUS WEIGHT; WILD TYPE; ANIMAL; BALLOON DILATATION; BLOOD; GENETICS; PHYSIOLOGY; SEXUAL DEVELOPMENT; SPRAGUE DAWLEY RAT; SYSTOLE;

ANIMALS; BALLOON DILATION; ENDOTHELIN-1; ESTROGENS; FEMALE; MALE; NEOINTIMA; OVARIECTOMY; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RNA, MESSENGER; SEX CHARACTERISTICS; SYSTOLE;

EID: 78751554087     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.165308     Document Type: Article

References (40)

1. Bush TL and Barrett-Connor E (1985) Noncontraceptive estrogen use and cardiovascular disease. Epidemiol Rev 7:89-104.
2. Chen SJ, Li H, Durand J, Oparil S, and Chen YF (1996) Estrogen reduces myointimal proliferation after balloon injury of rat carotid artery. Circulation 93:577-584. (Pubitemid 26043619)
3. B receptor mediates both vasodilation and vasoconstriction in vivo. Biochem Biophys Res Commun 186:867-873.
4. David FL, Carvalho MH, Cobra AL, Nigro D, Fortes ZB, Rebouças NA, and Tostes RC (2001) Ovarian hormones modulate endothelin-1 vascular reactivity and mRNA expression in DOCA-salt hypertensive rats. Hypertension 38:692-696.
5. B receptors, but not in calcium handling mechanisms, in deoxycorticosterone acetate-salt hypertension. Braz J Med Biol Res 35:1061-1068.
6. Ergul A, Shoemaker K, Puett D, and Tackett RL (1998) Gender differences in the expression of endothelin receptors in human saphenous veins in vitro. J Pharmacol Exp Ther 285:511-517. (Pubitemid 28237426)
7. Farhat MY, Lavigne MC, and Ramwell PW (1996) The vascular protective effects of estrogen. FASEB J 10:615-624.
8. Florian M, Freiman A, and Magder S (2004) Treatment with 17-β-estradiol reduces superoxide production in aorta of ovariectomized rats. Steroids 69:779-787.
9. B receptors in rats. Biochem Biophys Res Commun 199:1461-1465.
10. Gariepy CE, Ohuchi T, Williams SC, Richardson JA, and Yanagisawa M (2000) Salt-sensitive hypertension in endothelin-B receptor-deficient rats. J Clin Invest 105:925-933.
11. Gariepy CE, Williams SC, Richardson JA, Hammer RE, and Yanagisawa M (1998) Transgenic expression of the endothelin-B receptor prevents congenital intestinal aganglionosis in a rat model of Hirschsprung disease. J Clin Invest 102:1092-1101.
12. Godsland IF, Wynn V, Crook D, and Miller NE (1987) Sex, plasma lipoproteins, and atherosclerosis: prevailing assumptions and outstanding questions. Am Heart J 114:1467-1503.
13. Grady D, Rubin SM, Petitti DB, Fox CS, Black D, Ettinger B, Ernster VL, and Cummings SR (1992) Hormone therapy to prevent disease and prolong life in postmenopausal women. Ann Intern Med 117:1016-1037.
14. Hirata Y, Takagi Y, Fukuda Y, and Marumo F (1989) Endothelin is a potent mitogen for rat vascular smooth muscle cells. Atherosclerosis 78:225-228.
15. Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, and Vittinghoff E (1998) Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. J Am Med Assoc 280:605-613.
16. B receptor in gender differences in deoxycorticosterone acetate-salt-induced hypertension. Clin Exp Pharmacol Physiol 34:280-285.
17. Kirchengast M and Münter K (1998) Endothelin and restenosis. Cardiovasc Res 39:550-555.
18. B receptor system aggravates neointimal hyperplasia after balloon injury of rat carotid artery. J Pharmacol Exp Ther 331:998-1004.
19. Matsumura Y, Kuro T, Kobayashi Y, Konishi F, Takaoka M, Wessale JL, Opgenorth TJ, Gariepy CE, and Yanagisawa M (2000) Exaggerated vascular and renal pathology in endothelin-B receptor-deficient rats with deoxycorticosterone acetatesalt hypertension. Circulation 102:2765-2773.
20. A receptor antagonism reduces neointimal hyperplasia in a porcine coronary stent model. Circulation 97:2551-2556.
21. Mendelsohn ME and Karas RH (1999) The protective effects of estrogen on the cardiovascular system. N Engl J Med 340:1801-1811.
22. Miller AP, Chen YF, Xing D, Feng W, and Oparil S (2003) Hormone replacement therapy and inflammation interactions in cardiovascular disease. Hypertension 42:657-663. (Pubitemid 37237305)
23. Miyauchi T and Masaki T (1999) Pathophysiology of endothelin in the cardiovascular system. Annu Rev Physiol 61:391-415.
24. Mori T, Durand J, Chen Y, Thompson JA, Bakir S, and Oparil S (2000) Effects of short-term estrogen treatment on the neointimal response to balloon injury of rat carotid artery. Am J Cardiol 85:1276-1279.
25. B receptor in the pathogenesis of monocrotaline-induced pulmonary hypertension in rats. Eur J Pharmacol 496:159-165.
26. B endothelin receptor antagonist. J Pharmacol Exp Ther 289:1262-1270.
27. Pedersen SH, Nielsen LB, Mortensen A, Nilas L, and Ottesen B (2008) Progestin oppose the effects of estradiol on the endothelin-1 receptor type B in coronary arteries from ovariectomized hyperlipidemic rabbits. Menopause 15:503-510.
28. Rossow JE, Anderson GL, Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, et al. (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial. JAMA 288:321-333.
29. Sanmartín M, Fernández-Ortiz A, Fantidis P, Aragoncillo P, Fernández-Durango R, Rollín R, Alfonso F, Hernández R, Escaned J, and Macaya C (2003) Effects of bosentan on neointimal response following coronary angioplasty. Eur J Clin Invest 33:762-768.
30. Stampfer MJ, Colditz GA, Willett WC, Manson JE, Rosner B, Speizer FE, and Hennekens CH (1991) Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses' health study. N Engl J Med 325:756-762.
31. Sullivan JC, Pollock JS, and Pollock DM (2006) Superoxide-dependent hypertension in male and female endothelin B receptor-deficient rats. Exp Biol Med 231:818-823.
32. Takahashi M (2006) The role of endothelin-1 in vascular remodeling in vivo. Cardiovasc Res 71:4-5.
33. B receptor deficient rats: effect of a high-salt diet. Hypertension 41:657-662.
34. Tolbert T and Oparil S (2001) Cardiovascular effects of estrogen. Am J Hypertens 14:186S-193S.
35. Tostes RC, Fortes ZB, Callera GE, Montezano AC, Touyz RM, Webb RC, and Carvalho MH (2008) Endothelin, sex and hypertension. Clin Sci 114:85-97.
36. Walsh BW, Schiff I, Rosner B, Greenberg L, Ravnikar V, and Sacks FM (1991) Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins. N Engl J Med 325:1196-1204.
37. Wang X, Douglas SA, Louden C, Vickery-Clark LM, Feuerstein GZ, and Ohlstein EH (1996) Expression of endothelin-1, endothelin-3, endothelin-converting enzyme-1, and endothelin-A and endothelin-B receptor mRNA after angioplasty-induced neointimal formation in the rat. Circ Res 78:322-328. (Pubitemid 26040860)
38. Winkles JA, Alberts GF, Brogi E, and Libby P (1993) Endothelin-1 and endothelin receptor mRNA expression in normal and atherosclerotic human arteries. Biochem Biophys Res Commun 191:1081-1088.
39. Xing D, Nozell S, Chen YF, Hage F, and Oparil S (2009) Estrogen and mechanisms of vascular protection. Arterioscler Thromb Vasc Biol 29:289-295.
40. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, and Masaki T (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415.