The small peptide OGP(10-14) reduces proliferation and induces differentiation of TPO-primed M07-E cells through RHOA/TGFβ1/SFK pathway

Medical Science Monitor

Volumn 17, Issue 1, 2011, Pages

  Battolla, Barbara ^a   Bernardini, Nunzia ^a   Petrini, Mario ^a   Mattii, Letizia ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Human thrombopoietin (TPO); M07 e; OGP(10 14); RhoA; Src kinases; TGF 1

Indexed keywords

OSTEOGENIC GROWTH PEPTIDE (10 14); PEPTIDE; PROTEIN TYROSINE KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; OSTEOGENIC GROWTH PEPTIDE[10-14]; PENTAPEPTIDE; PROTEIN MP1; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR; ENDORPHIN; HISTORPHIN;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; MEGAKARYOBLAST; PROTEIN EXPRESSION; CELL CULTURE; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; IMAGE ANALYSIS; SIGNAL TRANSDUCTION; DRUG EFFECT; ENZYME IMMUNOASSAY; HEMATOPOIETIC STEM CELL; HUMAN; IMAGE PROCESSING; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; ENDORPHINS; HEMATOPOIETIC STEM CELLS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOENZYME TECHNIQUES; IMMUNOHISTOCHEMISTRY; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 78751527382     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/msm.881309     Document Type: Article

References (17)

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