Engineered heart tissue enables study of residual undifferentiated embryonic stem cell activity in a cardiac environment

Biotechnology and Bioengineering

Volumn 108, Issue 3, 2011, Pages 704-719

  Dengler, Jana ^a,b   Song, Hannah ^a   Thavandiran, Nimalan ^b   Massé, Stéphane ^c   Wood, Geoffrey A ^d   Nanthakumar, Kumaraswamy ^a,b,e,f,g   Zandstra, Peter W ^a,b,e,f,g   Radisic, Milica ^a,b,f,h  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c TORONTO GENERAL HOSPITAL   (Canada)

^d UNIVERSITY OF GUELPH   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f HEART AND STROKE FOUNDATION OF CANADA   (Canada)

^g UNIVERSITY HEALTH NETWORK   (Canada)

^h UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Cardiomyocyte; Cell transplantation; Embryonic stem cell; Tissue engineering

Indexed keywords

ANIMAL MODEL; CARDIAC CELL; CARDIAC DIFFERENTIATION; CARDIAC PROGENITORS; CARDIAC STRUCTURE; CARDIAC TROPONIN I; CARDIOMYOCYTES; CELL DIFFERENTIATION; CELL INJECTION; CELL SOURCES; CELL SURVIVAL; CELL TRANSPLANTATION; CONNECTIVE TISSUES; ELECTRICAL CONDUCTION; ELECTRICAL FIELD; EMBRYONIC STEM CELLS; EXCITATION THRESHOLD; FLUORESCENT PROTEIN; HEART TISSUES; HOST TISSUES; IN-VITRO; IN-VIVO; MECHANISTIC STUDIES; NEONATAL RAT CARDIOMYOCYTES; RESIDUAL ACTIVITY; TIME POINTS; TRANSGENIC MICE; UNDIFFERENTIATED CELLS;

BIOLOGICAL ORGANS; CELL GROWTH; CELL PROLIFERATION; HEART; MUSCULOSKELETAL SYSTEM; POLYMERASE CHAIN REACTION; STEM CELLS; TISSUE ENGINEERING; TUMORS;

CELL CULTURE;

PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; TROPONIN I; VASCULOTROPIN RECEPTOR 2; YELLOW FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE; CARTILAGE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CONNECTIVE TISSUE; ECTODERM; ELECTROSTIMULATION; EMBRYONIC STEM CELL; ENDODERM; EPITHELIUM; GANGLION; HEART; HEART MUSCLE CELL; MESODERM; MOUSE; NEURAL TUBE; NONHUMAN; PROTEIN EXPRESSION; RAT; STEM CELL TRANSPLANTATION; TERATOMA; TISSUE ENGINEERING;

ANIMALS; EMBRYONIC STEM CELLS; MICE; MICE, TRANSGENIC; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; TISSUE ENGINEERING;

ANIMALIA; MUS MUSCULUS; RATTUS;

EID: 78751500215     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22987     Document Type: Article

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