One-week antihypertensive effect of Ile-Gln-Pro in spontaneously hypertensive rats

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 2, 2011, Pages 559-563

  Lu, Jun ^a,b,c,d   Sawano, Yoriko ^a   Miyakawa, Takuya ^a   Xue, You Lin ^a   Cai, Mu Yi ^d   Egashira, Yukari ^c   Ren, Di Feng ^a,b   Tanokura, Masaru ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b BEIJING FORESTRY UNIVERSITY   (China)

^c CHIBA UNIVERSITY   (Japan)

^d NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

Author keywords

ACE inhibitory peptide; antihypertension; Ile Gln Pro; renin angiotensin system

Indexed keywords

ACE-INHIBITORY; ANGIOTENSIN I-CONVERTING ENZYME; ANGIOTENSIN II; ANTI-HYPERTENSION; ANTIHYPERTENSIVE EFFECT; DOWN-REGULATION; ILE-GLN-PRO; INHIBITORY PEPTIDES; MRNA EXPRESSION; MRNA LEVEL; NEGATIVE CONTROL; PRESSURE REDUCTION; RENIN-ANGIOTENSIN SYSTEM; SPIRULINA PLATENSIS; SPONTANEOUSLY HYPERTENSIVE RATS; SYSTOLIC BLOOD PRESSURE; TREATMENT GROUP; UP-REGULATION;

BLOOD; BLOOD PRESSURE; RATS; SPEED CONTROL;

PEPTIDES;

ANTIHYPERTENSIVE AGENT; PEPTIDE; RENIN;

ANIMAL; ARTICLE; BLOOD PRESSURE; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION; GENETICS; HUMAN; HYPERTENSION; MALE; METABOLISM; PATHOPHYSIOLOGY; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HUMANS; HYPERTENSION; MALE; PEPTIDES; RATS; RATS, INBRED SHR; RENIN;

RATTUS; SPIRULINA PLATENSIS;

EID: 78751493209     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf104126a     Document Type: Article

References (35)

1. Chobanian, A. V.; Bakris, G. L.; Black, H. R.; Cushman, W. C.; Green, L. A.; Izzo, J. L., Jr.; Jones, D. W.; Materson, B. J.; Oparil, S.; Wright, J. T., Jr.; Roccella, E. J.; Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee. Seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension 2003, 42, 1206 - 1252.
2. Ozturk, S.; Sar, F.; Bengi-Bozkurt, O.; Kazancioglu, R. Study of ACEI versus ARB in managing hypertensive overt diabetic nephropathy: Long-term analysis Kidney Blood Pressure Res. 2009, 32, 268-275
3. Skeggs, L. T., Jr.; Kahn, J. R.; Shumway, N. P. The isolation and assay of hypertensin from blood J. Exp. Med. 1952, 95, 241-246
4. Sood, N.; Reinhart, K. M.; Baker, W. L. Combination therapy for the management of hypertension: A review of the evidence Am. J. Health-Syst. Pharm. 2010, 67, 885-894
5. Warner, F. J.; Lubel, J. S.; McCaughan, G. W.; Angus, P. W. Liver fibrosis: A balance of ACEs? Clin. Sci. 2007, 113, 109-118
6. Brewster, U. C.; Perazella, M. A. The renin-angiotensin-aldosterone system and the kidney: Effects on kidney disease Am. J. Med. 2004, 116, 263-272
7. Shapiro, B. A.; Olala, L.; Arun, S. N.; Parker, P. M.; George, M. V.; Bollag, W. B. Angiotensin II-activated protein kinase D mediates acute aldosterone secretion Mol. Cell. Endocrinol. 2010, 317, 99-105
8. Zhu, L.; Carretero, O. A.; Liao, T. D.; Harding, P.; Li, H.; Sumners, C.; Yang, X. P. Role of prolylcarboxypeptidase in angiotensin II type 2 receptor-mediated bradykinin release in mouse coronary artery endothelial cells Hypertension 2010, 56, 384-390
9. Ondetti, M. A. Design of specific inhibitors of angiotensin converting enzyme: New class of orally active antihypertensive agents Science 1977, 196, 441-444
10. Atkinson, A. B.; Robertson, J. I. Captopril in the treatment of clinical hypertension and cardiac failure Lancet 1979, 2, 836-839
11. Murray, B. A.; FitzGerald, R. J. Angiotensin converting enzyme inhibitory peptides derived from food proteins: Biochemistry, bioactivity and production Curr. Pharm. Des. 2007, 13, 773-791
12. Pihlanto, A.; Akkanen, S.; Korhonen, H. J. ACE-inhibitory and antioxidant properties of potato (Solanum tuberosum) Food Chem. 2008, 109, 104-112
13. Chen, Z. Y.; Peng, C.; Jiao, R.; Wong, Y. M.; Yang, N.; Huang, Y. Anti-hypertensive nutraceuticals and functional foods J. Agric. Food. Chem. 2009, 57, 4485-4499
14. Seppo, L.; Jauhiainen, T.; Poussa, T.; Korpela, R. A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects Am. J. Clin. Nutr. 2003, 77, 326-330
15. Lee, D. H.; Kim, J. H.; Park, J. S.; Choi, Y. J.; Lee, J. S. Isolation and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from the edible mushroom Tricholoma giganteum Peptides 2004, 25, 621-627
16. Miguel, M.; López-Fandiño, R.; Ramos, M.; Aleixandre, A. Short-term effect of egg-white hydrolysate products on the arterial blood pressure of hypertensive rats Br. J. Nutr. 2005, 94, 731-737
17. Lu., J.; Ren, D. F.; Xue, Y. L.; Sawano, Y.; Miyakawa, T.; Tanokura, M. Isolation of an antihypertensive peptide from alcalase digest of Spirulina platensis J. Agric. Food Chem. 2010, 58, 7166-7171
18. Zhang, X. C.; Xin, S. X.; Li, Q. H.; Chen, G. X. Nutritional values of Spirulina. Spirulina: The Most Perfect Functional Food, 1 st ed.; Press of Ocean University of China: Qingdao, Peoples Republic of China, 1999; pp 54 - 83 (in Chinese).
19. Reeves, P. G.; Nielsen, F. H.; Fahey, G. C., Jr. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet J. Nutr. 1993, 123, 1939-1951
20. Paizis, G.; Cooper, M. E.; Schembri, J. M.; Tikellis, C.; Burrell, L. M.; Angus, P. W. Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver Gastroenterology 2002, 123, 1667-1676
21. Paizis, G.; Cooper, M. E.; Schembri, J. M.; Tikellis, C.; Burrell, L. M.; Angus, P. W. Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver Gastroenterology 2004, 126, 634
22. Vonend, O.; Apel, T.; Amann, K.; Sellin, L.; Stegbauer, J.; Ritz, E.; Rump, L. C. Modulation of gene expression by moxonidine in rats with chronic renal failure Nephrol., Dial., Transplant. 2004, 19, 2217-2222
23. Pfaffl, M. W. A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res. 2001, 29, 2002-2007
24. Rasmussen, R. Quantification on the LightCycler instrument. In Rapid Cycle Real-Time PCR, 1 st ed.; Meur, S. C.; Wittwer, C.; Nakagawara, K., Eds.; Springer: New York, 2001; pp 21 - 34.
25. Okamoto, K.; Aoki, K. Development of a strain of spontaneously hypertensive rats Jpn. Circ. J. 1963, 27, 282-293
26. Miguel, M.; Aleixandre, A. Antihypertensive peptides derived from egg proteins J. Nutr. 2006, 136, 1457-1460
27. Barney, C. C.; Katovich, M. J.; Fregly, M. J. The effect of acute administration of an angiotensin converting enzyme inhibitor, captopril (SQ 14,225), on experimentally induced thirst in rats J. Pharmacol. Exp. Ther. 1980, 12, 53-57
28. Kotov, A. V.; Tolpygo, S. M.; Pevtsova, E. I.; Obukhova, M. F. Protein-peptide complexes of angiotensins in the mechanisms of thirst motivation Neurosci. Behav. Physiol. 2003, 33, 811-819
29. Fujita, H.; Yoshikawa, M. LKPNM: A prodrug-type ACE-inhibitory peptide derived from fish protein Immunopharmacology 1999, 44, 123-127
30. Yamada, Y.; Matoba, N.; Usui, H.; Onishi, K.; Yoshikawa, M. Design of a highly potent anti-hypertensive peptide based on Ovokinin(2-7) Biosci., Biotechnol., Biochem. 2002, 66, 1213-1217
31. Bilanda, D. C.; Dimo, T.; Dzeufiet Djomeni, P. D.; Bella, N. M.; Aboubakar, O. B.; Nguelefack, T. B.; Tan, P. V.; Kamtchouing, P. Antihypertensive and antioxidant effects of Allanblackia floribunda Oliv. (Clusiaceae) aqueous extract in alcohol- and sucrose-induced hypertensive rats J. Ethnopharmacol. 2010, 128, 634-640
32. Bottari, S. P.; King, I. N.; Reichlin, S.; Dahlstroem, I.; Lydon, N.; de Gasparo, M. The angiotensin AT2 receptor stimulates protein tyrosine phosphatase activity and mediates inhibition of particulate guanylate cyclase Biochem. Biophys. Res. Commun. 1992, 183, 206-211
33. Dzau, V. J.; Sasamura, H.; Hein, L. Heterogeneity of angiotensin synthetic pathways and receptor subtypes: Physiological and pharmacological implications J. Hypertens. 1993, 11, S13-S18
34. Hall, J. E. Control of sodium excretion by angiotensin II: Intrarenal mechanisms and blood pressure regulation Am. J. Physiol. 1986, 250, R960-R972
35. Wong, M. K.; Ge, W.; Woo, N. Y. Positive feedback of hepatic angiotensinogen expression in silver sea bream (Sparus sarba) Mol. Cell. Endocrinol. 2007, 263, 103-111