Isolation of an antihypertensive peptide from alcalase digest of spirulina platensis

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 12, 2010, Pages 7166-7171

  Lu, Jun ^a,b   Ren, Di Feng ^a,b   Xue, You Lin ^a   Sawano, Yoriko ^a   Miyakawa, Takuya ^a   Tanokura, Masaru ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b BEIJING FORESTRY UNIVERSITY   (China)

Author keywords

ACE inhibitory peptide; Angiotensin I converting enzyme; Antihypertension; Spirulina platensis

Indexed keywords

ANTIHYPERTENSIVE AGENT; BACTERIAL PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PEPTIDE; SUBTILISIN;

ANIMAL; ARTICLE; BACILLUS; CHEMISTRY; DISEASE MODEL; ENZYMOLOGY; HUMAN; HYDROLYSIS; HYPERTENSION; ISOLATION AND PURIFICATION; KINETICS; MALE; RAT; SPIRULINA; SPONTANEOUSLY HYPERTENSIVE RAT; SYNTHESIS;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BACILLUS; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; HUMANS; HYDROLYSIS; HYPERTENSION; KINETICS; MALE; PEPTIDES; RATS; RATS, INBRED SHR; SPIRULINA; SUBTILISINS;

RATTUS; SPIRULINA PLATENSIS;

EID: 77953637834     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf100193f     Document Type: Article

References (34)

1. Ondetti, M. A.; Rubin, B.; Cushman, D. W. Enzyme of the rennin-angiotensin system and their inhibitors Annu. Rev. Biochem. 1982, 51, 283-308
2. Skeggs, L. T., Jr.; Kahn, J. R.; Shumway, N. P. The isolation and assay of hypertensin from blood J. Exp. Med. 1952, 95, 241-246
3. Timmermans, P. B.; Benfield, P.; Chiu, A. T.; Herblin, W. F.; Wong, P. C.; Smith, R. D. Angiotensin II receptors and functional correlates Am. J. Hypertens. 1992, 5, S221-235
4. Ondetti, M. A. Design of specific inhibitors of angiotensin converting enzyme: New class of orally active antihypertensive agents Science 1977, 196, 441-444
5. Suetsuna, K. Isolation and characterization of angiotensin I Converting enzyme inhibitor dipeptides derived from Allium sativum L (garlic) J. Nutr. Biochem. 1998, 9, 415-419
6. Atkinson, A. B.; Robertson, J. I. Captopril in the treatment of clinical hypertension and cardiac failure Lancet 1979, 2, 836-839
7. Chen, Z. Y.; Peng, C.; Jiao, R.; Wong, Y. M.; Yang, N.; Huang, Y. Anti-hypertensive nutraceuticals and functional foods J. Agric. Food. Chem. 2009, 57, 4485-4499
8. Maeno, M.; Yamamoto, N.; Takano, T. Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790 J. Dairy Sci. 1996, 79, 1316-1321
9. Yang, Y.; Tao, G.; Liu, P.; Liu, J. Peptide with angiotensin I-converting enzyme inhibitory activity from hydrolyzed corn gluten meal J. Agric. Food. Chem. 2007, 55, 7891-7895
10. Oshima, G.; Shimabukuro, H.; Nagasawa, K. Peptide inhibitors of angiotensin-converting enzyme in digests of gelatin by bacterial collagenase Biochim. Biophys. Acta 1979, 566, 128-137
11. Hyoung Lee, D.; Ho Kim, J.; Sik Park, J.; Jun Choi, Y.; Soo Lee, J. Isolation and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from the edible mushroom Tricholoma giganteum Peptides 2004, 25, 621-627
12. Okamoto, A.; Hanagata, H.; Kawamura, Y.; Yanagida, F. Anti-hypertensive substances in fermented soybean, natto Plant Foods Hum. Nutr. 1995, 47, 39-47
13. Yu, Y.; Hu, J.; Miyaguchi, Y.; Bai, X.; Du, Y.; Lin, B. Isolation and characterization of angiotensin I-converting enzyme inhibitory peptides derived from porcine hemoglobin Peptides 2006, 27, 2950-2956
14. Pihlanto, A.; Akkanen, S.; Korhonen, H. J. ACE-inhibitory and antioxidant properties of potato (Solanum tuberosum) Food Chem. 2008, 109, 104-112
15. Saito, Y.; Wanezaki, K.; Kawato, A.; Imayasu, S. Structure and activity of angiotensin I converting enzyme inhibitory peptides from sake and sake lees Biosci. Biotechnol. Biochem. 1994, 58, 1767-1771
16. Wu, J.; Ding, X. Characterization of inhibition and stability of soy-protein-derived angiotensin I-converting enzyme inhibitory peptides Food Res. Int. 2002, 35, 367-375
17. Kuba, M.; Tanaka, K.; Tawata, S.; Takeda, Y.; Yasuda, M. Angiotensin I-converting enzyme inhibitory peptides isolated from tofuyo fermented soybean food Biosci. Biotechnol. Biochem. 2003, 67, 1278-1283
18. Kohama, Y.; Oka, H.; Yamamoto, K.; Teramoto, T.; Okabe, M.; Mimura, T.; Nagase, Y.; Chiba, Y.; Fujita, T. Induction of angiotensin-converting enzyme inhibitory activity by acid-limited proteolysis of glyceraldehyde 3-phosphate dehydrogenase Biochem. Biophys. Res. Commun. 1989, 161, 456-460
19. Nagase, Y.; Satake, M. Potent synthetic analogues of angiotensin- converting enzyme inhibitor derived from tuna muscle Agric. Biol. Chem. 1991, 55, 2169-2170
20. Rodríguez-Hernández, A.; Blé-Castillo, J. L.; Juárez-Oropeza, M. A.; Díaz-Zagoya, J. C. Spirulina maxima prevents fatty liver formation in CD-1 male and female mice with experimental diabetes Life Sci. 2001, 69, 1029-1037
21. Hayashi, K.; Hayashi, T.; Kojima, I. A natural sulphated polysaccharide, calcium spirulin isolated from Spirulina platensis: in vitro and ex vivo evaluation of anti herpes simplex virus and anti human immunodeficiency virus activities AIDS Res. Hum. Retroviruses 1996, 12, 1463-1471
22. Mathew, B.; Sankaranarayanan, R.; Nair, P. P.; Varghese, C.; Somanathan, T.; Amma, B. P.; Amma, N. S.; Nair, M. K. Evaluation of chemoprevention of oral cancer with Spirulina fusiformis Nutr. Cancer 1995, 24, 197-202
23. Torres-Durán, P. V.; Miranda-Zamora, R.; Paredes-Carbajal, M. C.; Mascher, D.; Blé-Castillo, J.; Díaz-Zagoya, J. C.; Juárez-Oropeza, M. A. Studies on the preventive effect of Spirulina maxima on fatty liver development induced by carbon tetrachloride, in the rat J. Ethnopharmacol. 1999, 64, 141-147
24. Hirahashi, T.; Matsumoto, M.; Hazeki, K.; Saeki, Y.; Ui, M.; Seya, T. Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina plantesis Int. Immunopharmacol. 2002, 2, 423-434
25. He, H. L.; Chen, X. L.; Wu, H.; Sun, C. Y.; Zhang, Y. Z..; Zhou, B. C. High throughput and rapid screening of marine protein hydrolysates enriched in peptides with angiotensin-I-converting enzyme inhibitory activity by capillary electrophoresis Bioresour. Technol. 2007, 98, 3499-3505
26. Zhang, X. C.; Xin, S. X.; Li, Q. H.; Chen, G. X. Nutritional Values of Spirulina. In Spirulina: The Most Perfect Functional Food (in Chinese), 1 st ed.; Press of Ocean University of China: Qingdao, Peoples Republic of China, 1999; pp 54 -83.
27. Carmona, A. K.; Schwager, S. L.; Juliano, M. A.; Juliano, L.; Sturrock, E. D. A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay Nat. Protoc. 2006, 1, 1971-1976
28. Hayashi, O.; Katoh, T.; Okuwaki, Y. Enhancement of antibody production in mice by dietary Spirulina platensis J. Nutr. Sci. Vitaminol. 1994, 40, 431-441
29. Premkumar, K.; Abraham, S. K.; Santhiya, S. T.; Ramesh, A. Protective effect of Spirulina fusiformis on chemical-induced genotoxicity in mice Fitoterapia 2004, 75, 24-31
30. Otte, J.; Shalaby, M. A. S.; Zakora, M.; Nielsen, M. S. Fractionation and identification of ACE-inhibitory peptides from a-lactalbumin and b-casein produced by thermolysin-catalysed hydrolysis Int. Dairy J. 2007, 17, 1460-1472
31. Cheung, H.-S.; Wang, F.-L.; Ondetti, M. A.; Sabo, E. F.; Cushman, D. W. Binding of peptide substrates and inhibitors of angiotensin converting enzyme J. Biol. Chem. 1980, 255, 401-407
32. Nakamura, Y.; Yamamoto, N.; Sakai, K.; Okubo, A.; Yamazaki, S.; Takano, T. Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk J. Dairy Sci. 1995, 78, 777-783
33. Yokoyama, K.; Chiba, H.; Yoshikawa, M. Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito Biosci. Biotechnol. Biochem. 1992, 56, 1541-1545
34. Chun, H.; Sasaki, M.; Fujiyama, Y.; Bamba, T. Effect of peptide chain length on absorption and intact transport of hydrolyzed soybean peptide in rat intestinal everted sac J. Clin. Biochem. Nutr. 1996, 21, 131-140