Arctigenin suppresses unfolded protein response and sensitizes glucose deprivation-mediated cytotoxicity of cancer cells

Planta Medica

Volumn 77, Issue 2, 2011, Pages 141-145

  Sun, Shengrong ^a   Wang, Xiong ^b   Wang, Changhua ^c   Nawaz, Ahmed ^c   Wei, Wen ^a   Li, Juanjuan ^a   Wang, Lijun ^a   Yu, De Hua ^c  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF MEDICINE   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

2DG; arctigenin; cancer; cytotoxicity; glucose deprivation; GRP78; unfolded protein response (UPR)

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ARCTIGENIN; GLUCOSE; GLUCOSE RELATED PROTEIN 78; GLUCOSE RELATED PROTEIN 94; MEMBRANE PROTEIN; TUNICAMYCIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

CANCER CELL; CELL GROWTH; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; GENE EXPRESSION; GENETIC TRANSCRIPTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; REVIEW; SENSITIZATION; TRANSGENE; UNFOLDED PROTEIN RESPONSE;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL SURVIVAL; DNA-BINDING PROTEINS; FURANS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUCOSE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LIGNANS; MEMBRANE PROTEINS; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; UNFOLDED PROTEIN RESPONSE;

EID: 78651504429     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0030-1250179     Document Type: Review

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