Evaluating the effect of preoperative oral gabapentin on postoperative pain in patients receiving spinal anaesthesia for lower limb surgery

Southern African Journal of Anaesthesia and Analgesia

Volumn 16, Issue 6, 2010, Pages 9-12

  Raghove, P ^a   Jaiswal, R ^a   Singh, K ^a  

^a POST GRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Gabapentin; Pain; Postoperative; Rescue analgesia

Indexed keywords

BUPIVACAINE; GABAPENTIN; LIDOCAINE; PLACEBO; TRAMADOL;

ADJUVANT THERAPY; ADULT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HUMAN; LUMBAR PUNCTURE; MAJOR CLINICAL STUDY; MALE; PAIN ASSESSMENT; POSTOPERATIVE PAIN; PREOPERATIVE TREATMENT; SEDATION; SPINAL ANESTHESIA;

EID: 78651498388     PISSN: 22201181     EISSN: None     Source Type: Journal    
DOI: 10.1080/22201173.2010.10872711     Document Type: Article

References (15)

1. Morgan GE, Mikhail MS, Murray MJ, eds. Pain management. In: Clinical Anesthesiology. New York: Lange Medical Books. 2002:309-58.
2. Rosner H, Rubin L, Kestenbaum A. Gabapentin adjunctive therapy in neuropathic pain states. Clin J Pain 1996;12:56-8.
3. Backonja M, Beydoun A, Edwards KR, et al. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. JAMA 1998;280:1831-6.
4. Kong VKF, Irwin MG. Gabapentin: a multimodal perioperative drug. Br J Anaesth 2007;99:775-86.
5. Werner MU, Perkins FM, Holte K, Pedersen JL, Kehlet H. Effects of gabapentin in acute inflammatory pain in humans. Reg Anesth Pain Med 2001;26:322-8.
6. Field MJ, Holloman EF, McCleary S. Evaluation of gabapentin and S-(+)-3-isobutylgaba in rat model of postoperative pain. J Pharmacol Exp Ther 1997;282:1242-6.
7. Dirks J, Frendenstorg BB, Christensen D, Fomsgaard JS, Flyger H, Dahl JB. A randomized study of the effects of single dose gabapentin verses placebo on postoperative pain and morphine consumption after mastectomy. Anesthesiology 2002;97:560-4.
8. Turan A, Karamanlioglu B, Memis D, Usar P, Pamukcu Z, Ture M. The analgesic effects of gabapentin after total abdominal hysterectomy. Anesth Analg 2004;98:1370-3. (Pubitemid 38525595)
9. Pandey CK, Priye S, Singh S, Singh U, Singh RB, Singh PK. Preemptive use of gabapentin significantly decreases postoperative pain and rescue analgesic requirements in laparoscopic cholecystectomy. Can J Anaesth 2004;51:358-63.
10. Pandey CK, Sahay S, Gupta D. Preemptive gabapentin decreases postoperative pain after lumbar discoidectomy. Can J Anaesth 2004;51:989-9.
11. Turan A, Karamanlioglu B, Yagiz R, Pamukcu Z, Yavuz E. The analgesic effects of gabapentin after spinal surgery. Anesthesiology 2004;100:935-8. (Pubitemid 38392582)
12. Turan A, Kaya G, Karamanlioglu B, Pamukcu Z, Apfll CC. Effect of oral gabapentin on postoperative epidural analgesia. Br J Anaesth 2006;96:242-5.
13. Pandey CK, Navkar DV, Giri PJ. Evaluation of optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized double blind placebo controlled study. J Neurosurg Anesthesiol 2005;17:65-8.
14. Adam F, Menigaux C, Sessler DI, Chauvin M. A single preoperative dose of gabapentin (800 mg) does not augment postoperative analgesia in patients given interscalene brachial plexus blocks for arthroscopic shoulder surgery. Anesth Analg 2006;103:1278-82.
15. Taylor CP. Gabapentin: mechanisms of action. In: Levy RH, Mattson RH, Meldrum BS, Perucca, eds. Antiepileptic drugs. Philadelphia: Lippincott Williams and Wilkins; 2002:321-34.