Modeling the competition between aggregation and self-assembly during virus-like particle processing

Biotechnology and Bioengineering

Volumn 107, Issue 3, 2010, Pages 550-560

  Ding, Yong ^a   Chuan, Yap Pang ^a   He, Lizhong ^a   Middelberg, Anton P J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Aggregation; Critical concentration; Modeling; Self assembly; Virus like particles

Indexed keywords

AGGREGATION; AGGREGATION BEHAVIOR; BIO-MOLECULAR; BIOTHERAPEUTICS; CONCENTRATION DEPENDENCE; CRITICAL CONCENTRATION; EFFICIENT METHOD; LOW COSTS; MODELING; NON-NATIVE; PHARMACEUTICAL PROTEIN; PRODUCT YIELDS; PROTEIN AGGREGATION; PROTEIN SUBUNITS; QUALITY CONSISTENCY; REALISTIC MODEL; SCALE-UP; SECOND ORDERS; SELF-ASSEMBLING; VIRUS ASSEMBLY; VIRUS-LIKE PARTICLES;

ASSEMBLY; MANUFACTURE; MATHEMATICAL MODELS; PROTEINS; SELF ASSEMBLY; VIRUSES; MODELS; QUALITY CONTROL;

AGGLOMERATION;

PROTEIN SUBUNIT;

ARTICLE; BIOENGINEERING; CONTROLLED STUDY; DIMERIZATION; MATHEMATICAL MODEL; MOLECULAR MECHANICS; NONHUMAN; PROTEIN AGGREGATION; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS LIKE AGENT; PROTEIN ASSEMBLY; VIROGENESIS;

MODELS, THEORETICAL; PROTEIN DENATURATION; VIRAL PROTEINS; VIROSOMES; VIRUS ASSEMBLY;

MIRIDAE;

EID: 78651478069     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22821     Document Type: Article

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