Evaluation of 11β-hydroxysteroid dehydrogenase type 1 activity in female patients with rheumatoid arthritis;Hodnotenie aktivity 11β-hydroxysteroid dehydrogenázy typu 1 u pacientiek s reumatoidnou artritídou

Vnitrni Lekarstvi

Volumn 56, Issue 12, 2010, Pages 1274-1278

  Kerlik, J ^a   Rovensky J ^b   Vogeser, M ^c   Vlcek M ^a   Imrich, R ^a   Penesova A ^a   Radikova Z ^a  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

^b NATIONAL INSTITUTE OF RHEUMATIC DISEASES   (Slovakia)

^c Institut Klinickej Chémie   (Czech Republic)

Author keywords

11 hydroxysteroid dehydrogenase type 1; Cortisol; Relative adrenal insufficiency; Rheumatoid arthritis

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; CORTISONE ACETATE; HYDROCORTISONE;

ADIPOSE TISSUE; ADULT; ARTICLE; CHEMICAL MODIFICATION; CHRONIC INFLAMMATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; INFLAMMATION; RHEUMATOID ARTHRITIS; SALIVA; BLOOD; ENZYMOLOGY;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADULT; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; HYDROCORTISONE;

EID: 78651477928     PISSN: 0042773X     EISSN: 18017592     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Raison CL, Miller AH. When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatry 2003; 160: 1554-1565.
2. Edwards CR, Benediktsson R, Lindsay RS et al. 11 beta-Hydroxysteroid dehydrogenases: key enzymes in determining tissue-specific glucocorticoid effects. Steroids 1996; 61: 263-269. (Pubitemid 26144433)
3. Tomlinson JW, Walker EA, Bujalska IL et al. 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Rev 2004; 25: 831-866.
4. Imrich R, RovenskyJ, Malis F et al. Low levels of dehydroepiandrosterone sulphate in plasma, and reduced sympathoadrenal response to hypoglycaemia in premenopausal women with rheumatoid arthritis. Ann Rheum Dis 2005; 64: 202-206.
5. Jessop DS, Harbuz MS. A defect in Cortisol production in rheumatoid arthritis: why are we still looking? Rheumatology (Oxford) 2005; 44: 1097-1100.
6. Straub RH, Paimela L, Peltomaa R et al. Inadequately low serum levels of steroid hormones in relation to interleukin-6 and tumor necrosis factor in untreated patients with early rheumatoid arthritis and reactive arthritis. Arthritis Rheum 2002; 46: 654-662. (Pubitemid 34214248)
7. Imrich R, Vigas M, RovenskyJ et al. Adrenal plasma steroid relations in glucocorticoid-naïve premenopausal rheumatoid arthritis patients during insulin-induced hypoglycemia test compared to matched normal control females. Endocr Regul 2009; 43: 65-73.
8. Schlaghecke R, Kornely E, Wollenhaupt J et al. Glucocorticoid receptors in rheumatoid arthritis. Arthritis Rheum 1992; 35: 740-744.
9. Hardy RS, Filer A, Cooper MS et al. Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation. Arthritis Res Ther 2006; 8: R108.
10. Schmidt M, Weidler C, Naumann H et al. Reduced capacity for the reactivation of glucocorticoids in rheumatoid arthritis synovial cells: possible role of the sympathetic nervous system? Arthritis Rheum 2005; 52: 1711-1720.
11. Bastard JP, Jardel C, Bruckert E et al. Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss. J Clin Endocrinol Metab 2000; 85: 3338-3342.
12. Tomlinson JW, Moore J, Cooper MS et al. Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines. Endocrinology 2001; 142: 1982-1989.
13. Prins JB, Niesler CU, Winterford CM et al. Tumor necrosis factor-alpha induces apoptosis of human adipose cells. Diabetes 1997; 46: 1939-1944. (Pubitemid 27512077)
14. Vogeser M, Möhnle P, Briegel J. Free serum Cortisol: quantification applying equilibrium dialysis or ultrafiltration and an automated immunoassay system. Clin Chem Lab Med 2007; 45: 521-525. (Pubitemid 46632224)
15. Stewart PM, Boulton A, Kumar S et al. Cortisol metabolism in human obesity: impaired cortisone → cortisol conversion in subjects with central adiposity. J Clin Endocrinol Metab 1999; 84: 1022-1027.
16. Rask E, OlssonT, Söderberg S et al. Tissue-specific dysregulation of cortisol metabolism in human obesity. J Clin Endocrinol Metab 2001; 86: 1418-1421. (Pubitemid 32323037)
17. Koska J, de Courten B, Wake DJ et al. 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue and prospective changes in body weight and insulin resistance. Obesity (Silver Spring) 2006; 14: 1515-1522.
18. Katz JR, Mohamed-Ali V, Wood PJ et al. An in vivo study of the cortisol-cortisone shuttle in subcutaneous abdominal adipose tissue. Clin Endocrinol (Oxf) 1999; 50: 63-68. (Pubitemid 29079369)
19. Sandeep TC, Andrew R, Homer NZ et al. Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11 beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone. Diabetes 2005; 54: 872-879. (Pubitemid 40322093)
20. Schmidt MI, Saad MJ, Duncan BB. Subclinical inflammation and obesity, diabetes and related disorders. Drug Discovery Today Disease Mechanisms 2005; 2: 307-312.
21. Tataranni PA. Relationship between subclinical inflammation, obesity, diabetes and related disorders. Drug Discovery Today Disease Mechanisms 2005; 2: 303-306.
22. Rovensky J, Imrich R, KoskaJ et al. Cortisol elimination from plasma in premenopausal women with rheumatoid arthritis. Ann Rheum Dis 2003; 62: 674-676. (Pubitemid 36760569)