메뉴 건너뛰기




Volumn 24, Issue 1, 2011, Pages 148-164

Post-transcriptional regulation controlled by E-cadherin is important for c-Jun activity in melanoma

Author keywords

C Jun; Cytoskeleton; E cadherin; Malignant melanoma; Post transcriptional regulation

Indexed keywords

PROTEIN C JUN; UVOMORULIN;

EID: 78651458117     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2010.00787.x     Document Type: Article
Times cited : (31)

References (64)
  • 2
    • 0024362088 scopus 로고
    • AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells
    • Bernstein, L.R., and Colburn, N.H. (1989). AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science 244, 566-569.
    • (1989) Science , vol.244 , pp. 566-569
    • Bernstein, L.R.1    Colburn, N.H.2
  • 6
    • 0028203632 scopus 로고
    • Oncogene activation and tumor suppressor gene inactivation during multistage mouse skin carcinogenesis
    • Bowden, G.T., Schneider, B., Domann, R., and Kulesz-Martin, M. (1994). Oncogene activation and tumor suppressor gene inactivation during multistage mouse skin carcinogenesis. Cancer Res. 54, 1882s-1885s.
    • (1994) Cancer Res. , vol.54
    • Bowden, G.T.1    Schneider, B.2    Domann, R.3    Kulesz-Martin, M.4
  • 7
    • 0024503589 scopus 로고
    • Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha
    • Brenner, D.A., O'Hara, M., Angel, P., Chojkier, M., and Karin, M. (1989). Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha. Nature 337, 661-663.
    • (1989) Nature , vol.337 , pp. 661-663
    • Brenner, D.A.1    O'Hara, M.2    Angel, P.3    Chojkier, M.4    Karin, M.5
  • 8
    • 49649109964 scopus 로고    scopus 로고
    • Development of a preclinical model of spontaneous human melanoma central nervous system metastasis
    • Cruz-Munoz, W., Man, S., Xu, P., and Kerbel, R.S. (2008). Development of a preclinical model of spontaneous human melanoma central nervous system metastasis. Cancer Res. 68, 4500-4505.
    • (2008) Cancer Res. , vol.68 , pp. 4500-4505
    • Cruz-Munoz, W.1    Man, S.2    Xu, P.3    Kerbel, R.S.4
  • 9
    • 0028144846 scopus 로고
    • c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK
    • Deng, T., and Karin, M. (1994). c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK. Nature 371, 171-175.
    • (1994) Nature , vol.371 , pp. 171-175
    • Deng, T.1    Karin, M.2
  • 10
    • 0026341905 scopus 로고
    • Rapid and preferential activation of the c-jun gene during the mammalian UV response
    • Devary, Y., Gottlieb, R.A., Lau, L.F., and Karin, M. (1991). Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol. Cell. Biol. 11, 2804-2811.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 2804-2811
    • Devary, Y.1    Gottlieb, R.A.2    Lau, L.F.3    Karin, M.4
  • 11
    • 0027049804 scopus 로고
    • The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases
    • Devary, Y., Gottlieb, R.A., Smeal, T., and Karin, M. (1992). The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 71, 1081-1091.
    • (1992) Cell , vol.71 , pp. 1081-1091
    • Devary, Y.1    Gottlieb, R.A.2    Smeal, T.3    Karin, M.4
  • 12
    • 4243687105 scopus 로고    scopus 로고
    • The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive
    • Dhar, A., Young, M.R., and Colburn, N.H. (2002). The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive. Mol. Cell. Biochem. 234-235, 185-193.
    • (2002) Mol. Cell. Biochem. , vol.234-235 , pp. 185-193
    • Dhar, A.1    Young, M.R.2    Colburn, N.H.3
  • 13
    • 0028079661 scopus 로고
    • Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells
    • Dong, Z., Birrer, M.J., Watts, R.G., Matrisian, L.M., and Colburn, N.H. (1994). Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc. Natl. Acad. Sci. USA 91, 609-613.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 609-613
    • Dong, Z.1    Birrer, M.J.2    Watts, R.G.3    Matrisian, L.M.4    Colburn, N.H.5
  • 14
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: a double-edged sword in tumorigenesis
    • Eferl, R., and Wagner, E.F. (2003). AP-1: a double-edged sword in tumorigenesis. Nat. Rev. Cancer 3, 859-868.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 16
    • 0033816924 scopus 로고    scopus 로고
    • Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer
    • Grady, W.M., Willis, J., Guilford, P.J. et al. (2000). Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer. Nat. Genet. 26, 16-17.
    • (2000) Nat. Genet. , vol.26 , pp. 16-17
    • Grady, W.M.1    Willis, J.2    Guilford, P.J.3
  • 18
    • 0028905076 scopus 로고
    • Transcription factor ATF2 regulation by the JNK signal transduction pathway
    • Gupta, S., Campbell, D., Derijard, B., and Davis, R.J. (1995). Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267, 389-393.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Derijard, B.3    Davis, R.J.4
  • 19
  • 22
    • 0033838767 scopus 로고    scopus 로고
    • E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors
    • Hsu, M.Y., Meier, F.E., Nesbit, M., Hsu, J.Y., Van Belle, P., Elder, D.E., and Herlyn, M. (2000). E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am. J. Pathol. 156, 1515-1525.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1515-1525
    • Hsu, M.Y.1    Meier, F.E.2    Nesbit, M.3    Hsu, J.Y.4    Van Belle, P.5    Elder, D.E.6    Herlyn, M.7
  • 23
    • 0031810051 scopus 로고    scopus 로고
    • In vitro modulation of human melanoma cell invasion and proliferation by all-trans-retinoic acid
    • Jacob, K., Wach, F., Holzapfel, U., Hein, R., Lengyel, E., Buettner, R., and Bosserhoff, A.K. (1998). In vitro modulation of human melanoma cell invasion and proliferation by all-trans-retinoic acid. Melanoma Res. 8, 211-219.
    • (1998) Melanoma Res. , vol.8 , pp. 211-219
    • Jacob, K.1    Wach, F.2    Holzapfel, U.3    Hein, R.4    Lengyel, E.5    Buettner, R.6    Bosserhoff, A.K.7
  • 24
    • 0031454580 scopus 로고    scopus 로고
    • Cadherin and catenin biology represent a global mechanism for epithelial cancer progression
    • Jankowski, J.A., Bruton, R., Shepherd, N., and Sanders, D.S. (1997). Cadherin and catenin biology represent a global mechanism for epithelial cancer progression. Mol. Pathol. 50, 289-290.
    • (1997) Mol. Pathol. , vol.50 , pp. 289-290
    • Jankowski, J.A.1    Bruton, R.2    Shepherd, N.3    Sanders, D.S.4
  • 25
    • 0035971432 scopus 로고    scopus 로고
    • AP-1 in mouse development and tumorigenesis
    • Jochum, W., Passegue, E., and Wagner, E.F. (2001). AP-1 in mouse development and tumorigenesis. Oncogene 20, 2401-2412.
    • (2001) Oncogene , vol.20 , pp. 2401-2412
    • Jochum, W.1    Passegue, E.2    Wagner, E.F.3
  • 26
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin, M. (1995). The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 270, 16483-16486.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 27
    • 0141723393 scopus 로고    scopus 로고
    • Role of JNK in tumor development
    • Kennedy, N.J., and Davis, R.J. (2003). Role of JNK in tumor development. Cell Cycle 2, 199-201.
    • (2003) Cell Cycle , vol.2 , pp. 199-201
    • Kennedy, N.J.1    Davis, R.J.2
  • 28
    • 65249099061 scopus 로고    scopus 로고
    • Loss of E-cadherin mediated cell-cell contacts activates a novel mechanism for upregulation of the proto-oncogene c-Jun
    • Knirsh, R., Ben Dror, I., Spangler, B., Matthews, G.D., Kuphal, S., Bosserhoff, A.K., and Vardimon, L. (2009). Loss of E-cadherin mediated cell-cell contacts activates a novel mechanism for upregulation of the proto-oncogene c-Jun. Mol. Biol. Cell. 20, 2121-9.
    • (2009) Mol. Biol. Cell. , vol.20 , pp. 2121-9
    • Knirsh, R.1    Ben Dror, I.2    Spangler, B.3    Matthews, G.D.4    Kuphal, S.5    Bosserhoff, A.K.6    Vardimon, L.7
  • 29
    • 0028979956 scopus 로고
    • Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin
    • Knudsen, K.A., Soler, A.P., Johnson, K.R., and Wheelock, M.J. (1995). Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J. Cell Biol. 130, 67-77.
    • (1995) J. Cell Biol. , vol.130 , pp. 67-77
    • Knudsen, K.A.1    Soler, A.P.2    Johnson, K.R.3    Wheelock, M.J.4
  • 30
    • 0033961711 scopus 로고    scopus 로고
    • c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents
    • Kolbus, A., Herr, I., Schreiber, M., Debatin, K.M., Wagner, E.F., and Angel, P. (2000). c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents. Mol. Cell. Biol. 20, 575-582.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 575-582
    • Kolbus, A.1    Herr, I.2    Schreiber, M.3    Debatin, K.M.4    Wagner, E.F.5    Angel, P.6
  • 31
    • 41549126681 scopus 로고    scopus 로고
    • Distinct signaling pathways of microtubule inhibitors - vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively
    • Kolomeichuk, S.N., Terrano, D.T., Lyle, C.S., Sabapathy, K., and Chambers, T.C. (2008). Distinct signaling pathways of microtubule inhibitors - vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively. FEBS J. 275, 1889-1899.
    • (2008) FEBS J. , vol.275 , pp. 1889-1899
    • Kolomeichuk, S.N.1    Terrano, D.T.2    Lyle, C.S.3    Sabapathy, K.4    Chambers, T.C.5
  • 32
    • 0025882879 scopus 로고
    • The jun and fos protein families are both required for cell cycle progression in fibroblasts
    • Kovary, K., and Bravo, R. (1991). The jun and fos protein families are both required for cell cycle progression in fibroblasts. Mol. Cell. Biol. 11, 4466-4472.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4466-4472
    • Kovary, K.1    Bravo, R.2
  • 33
    • 30544454763 scopus 로고    scopus 로고
    • Influence of the cytoplasmic domain of E-cadherin on endogenous N-cadherin expression in malignant melanoma
    • Kuphal, S., and Bosserhoff, A.K. (2006). Influence of the cytoplasmic domain of E-cadherin on endogenous N-cadherin expression in malignant melanoma. Oncogene 25, 248-259.
    • (2006) Oncogene , vol.25 , pp. 248-259
    • Kuphal, S.1    Bosserhoff, A.K.2
  • 34
    • 9144247129 scopus 로고    scopus 로고
    • Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma
    • Kuphal, S., Poser, I., Jobin, C., Hellerbrand, C., and Bosserhoff, A.K. (2004). Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma. Oncogene 23, 8509-8519.
    • (2004) Oncogene , vol.23 , pp. 8509-8519
    • Kuphal, S.1    Poser, I.2    Jobin, C.3    Hellerbrand, C.4    Bosserhoff, A.K.5
  • 36
    • 34247606483 scopus 로고    scopus 로고
    • Rewired ERK-JNK signaling pathways in melanoma
    • Lopez-Bergami, P., Huang, C., Goydos, J.S. et al. (2007). Rewired ERK-JNK signaling pathways in melanoma. Cancer Cell 11, 447-460.
    • (2007) Cancer Cell , vol.11 , pp. 447-460
    • Lopez-Bergami, P.1    Huang, C.2    Goydos, J.S.3
  • 39
    • 10744228941 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 but not Mel-CAM and/or beta3 integrin promotes progression of melanocytes to melanoma
    • Meier, F., Caroli, U., Satyamoorthy, K. et al. (2003). Fibroblast growth factor-2 but not Mel-CAM and/or beta3 integrin promotes progression of melanocytes to melanoma. Exp. Dermatol. 12, 296-306.
    • (2003) Exp. Dermatol. , vol.12 , pp. 296-306
    • Meier, F.1    Caroli, U.2    Satyamoorthy, K.3
  • 41
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes, C.D., and Hall, A. (1995). Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 42
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • Onder, T.T., Gupta, P.B., Mani, S.A., Yang, J., Lander, E.S., and Weinberg, R.A. (2008). Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 68, 3645-3654.
    • (2008) Cancer Res. , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 43
    • 0026518504 scopus 로고
    • Molecular organization of the uvomorulin-catenin complex
    • Ozawa, M., and Kemler, R. (1992). Molecular organization of the uvomorulin-catenin complex. J. Cell Biol. 116, 989-996.
    • (1992) J. Cell Biol. , vol.116 , pp. 989-996
    • Ozawa, M.1    Kemler, R.2
  • 44
    • 0025374899 scopus 로고
    • Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule
    • Ozawa, M., Ringwald, M., and Kemler, R. (1990). Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc. Natl. Acad. Sci. USA 87, 4246-4250.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4246-4250
    • Ozawa, M.1    Ringwald, M.2    Kemler, R.3
  • 47
    • 1642555931 scopus 로고    scopus 로고
    • Transcription factors involved in development and progression of malignant melanoma
    • Poser, I., and Bosserhoff, A.K. (2004). Transcription factors involved in development and progression of malignant melanoma. Histol. Histopathol. 19, 173-188.
    • (2004) Histol. Histopathol. , vol.19 , pp. 173-188
    • Poser, I.1    Bosserhoff, A.K.2
  • 48
    • 0035816677 scopus 로고    scopus 로고
    • Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail
    • Poser, I., Dominguez, D., de Herreros, A.G., Varnai, A., Buettner, R., and Bosserhoff, A.K. (2001). Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail. J. Biol. Chem. 276, 24661-24666.
    • (2001) J. Biol. Chem. , vol.276 , pp. 24661-24666
    • Poser, I.1    Dominguez, D.2    de Herreros, A.G.3    Varnai, A.4    Buettner, R.5    Bosserhoff, A.K.6
  • 49
    • 4444246328 scopus 로고    scopus 로고
    • Functional role of MIA in melanocytes and early development of melanoma
    • Poser, I., Tatzel, J., Kuphal, S., and Bosserhoff, A.K. (2004). Functional role of MIA in melanocytes and early development of melanoma. Oncogene 23, 6115-6124.
    • (2004) Oncogene , vol.23 , pp. 6115-6124
    • Poser, I.1    Tatzel, J.2    Kuphal, S.3    Bosserhoff, A.K.4
  • 51
    • 0028989005 scopus 로고
    • Reduced alpha-catenin and E-cadherin expression in breast cancer
    • Rimm, D.L., Sinard, J.H., and Morrow, J.S. (1995). Reduced alpha-catenin and E-cadherin expression in breast cancer. Lab. Invest. 72, 506-512.
    • (1995) Lab. Invest. , vol.72 , pp. 506-512
    • Rimm, D.L.1    Sinard, J.H.2    Morrow, J.S.3
  • 52
    • 0028094958 scopus 로고
    • Expression and transcriptional activity of AP-1, CRE, and URE binding proteins in B16 mouse melanoma subclones
    • Rutberg, S.E., Goldstein, I.M., Yang, Y.M., Stackpole, C.W., and Ronai, Z. (1994). Expression and transcriptional activity of AP-1, CRE, and URE binding proteins in B16 mouse melanoma subclones. Mol. Carcinog. 10, 82-87.
    • (1994) Mol. Carcinog. , vol.10 , pp. 82-87
    • Rutberg, S.E.1    Goldstein, I.M.2    Yang, Y.M.3    Stackpole, C.W.4    Ronai, Z.5
  • 53
    • 0024110719 scopus 로고
    • Induction of protooncogene c-jun by serum growth factors
    • Ryder, K., and Nathans, D. (1988). Induction of protooncogene c-jun by serum growth factors. Proc. Natl. Acad. Sci. USA 85, 8464-8467.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8464-8467
    • Ryder, K.1    Nathans, D.2
  • 54
    • 0007936466 scopus 로고    scopus 로고
    • Alterations in cadherin and catenin expression during the biological progression of melanocytic tumours
    • Sanders, D.S., Blessing, K., Hassan, G.A., Bruton, R., Marsden, J.R., and Jankowski, J. (1999). Alterations in cadherin and catenin expression during the biological progression of melanocytic tumours. Mol. Pathol. 52, 151-157.
    • (1999) Mol. Pathol. , vol.52 , pp. 151-157
    • Sanders, D.S.1    Blessing, K.2    Hassan, G.A.3    Bruton, R.4    Marsden, J.R.5    Jankowski, J.6
  • 55
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • Shaulian, E., and Karin, M. (2001). AP-1 in cell proliferation and survival. Oncogene 20, 2390-2400.
    • (2001) Oncogene , vol.20 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 56
    • 0033638915 scopus 로고    scopus 로고
    • The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest
    • Shaulian, E., Schreiber, M., Piu, F., Beeche, M., Wagner, E.F., and Karin, M. (2000). The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell 103, 897-907.
    • (2000) Cell , vol.103 , pp. 897-907
    • Shaulian, E.1    Schreiber, M.2    Piu, F.3    Beeche, M.4    Wagner, E.F.5    Karin, M.6
  • 57
    • 0032413528 scopus 로고    scopus 로고
    • E-cadherin/catenin complex in benign and malignant melanocytic lesions
    • Silye, R., Karayiannakis, A.J., Syrigos, K.N. et al. (1998). E-cadherin/catenin complex in benign and malignant melanocytic lesions. J. Pathol. 186, 350-355.
    • (1998) J. Pathol. , vol.186 , pp. 350-355
    • Silye, R.1    Karayiannakis, A.J.2    Syrigos, K.N.3
  • 58
    • 0025788098 scopus 로고
    • Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
    • Smeal, T., Binetruy, B., Mercola, D.A., Birrer, M., and Karin, M. (1991). Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354, 494-496.
    • (1991) Nature , vol.354 , pp. 494-496
    • Smeal, T.1    Binetruy, B.2    Mercola, D.A.3    Birrer, M.4    Karin, M.5
  • 59
    • 0028176375 scopus 로고
    • Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells
    • Sommers, C.L., Gelmann, E.P., Kemler, R., Cowin, P., and Byers, S.W. (1994). Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells. Cancer Res. 54, 3544-3552.
    • (1994) Cancer Res. , vol.54 , pp. 3544-3552
    • Sommers, C.L.1    Gelmann, E.P.2    Kemler, R.3    Cowin, P.4    Byers, S.W.5
  • 60
    • 0027938682 scopus 로고
    • A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated
    • Stappert, J., and Kemler, R. (1994). A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated. Cell Adhes. Commun. 2, 319-327.
    • (1994) Cell Adhes. Commun. , vol.2 , pp. 319-327
    • Stappert, J.1    Kemler, R.2
  • 61
    • 3843108220 scopus 로고    scopus 로고
    • Deregulated repression of c-Jun provides a potential link to its role in tumorigenesis
    • Weiss, C., and Bohmann, D. (2004). Deregulated repression of c-Jun provides a potential link to its role in tumorigenesis. Cell Cycle 3, 111-113.
    • (2004) Cell Cycle , vol.3 , pp. 111-113
    • Weiss, C.1    Bohmann, D.2
  • 63
    • 0034650759 scopus 로고    scopus 로고
    • A dominant role for the c-Jun NH2-terminal kinase in oncogenic ras-induced morphologic transformation of human lung carcinoma cells
    • Xiao, L., and Lang, W. (2000). A dominant role for the c-Jun NH2-terminal kinase in oncogenic ras-induced morphologic transformation of human lung carcinoma cells. Cancer Res. 60, 400-408.
    • (2000) Cancer Res. , vol.60 , pp. 400-408
    • Xiao, L.1    Lang, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.