Long-term but not short-term aspirin treatment attenuates diabetes-associated learning and memory decline in mice

Experimental and Clinical Endocrinology and Diabetes

Volumn 119, Issue 1, 2011, Pages 36-40

  Wang, T ^a,b   Fu, F H ^b   Han, B ^b   Zhang, L M ^b   Zhang, X M ^a  

^a SHANDONG UNIVERSITY   (China)

^b YANTAI UNIVERSITY   (China)

Author keywords

aspirin; diabetes; learning; memory

Indexed keywords

ACETYLCHOLINESTERASE; ACETYLSALICYLIC ACID; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; ESCAPE BEHAVIOR; GLUCOSE BLOOD LEVEL; HIPPOCAMPUS; INSULIN BLOOD LEVEL; LEARNING DISORDER; MALE; MEMORY DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; STREPTOZOCIN DIABETES; TREATMENT DURATION;

ACETYLCHOLINESTERASE; ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BLOOD GLUCOSE; COGNITION DISORDERS; DIABETES MELLITUS, EXPERIMENTAL; DRUG ADMINISTRATION SCHEDULE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPUS; INTERLEUKIN-1BETA; MAZE LEARNING; MEMORY; MICE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78651455044     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0030-1261933     Document Type: Article

References (25)

1. Akassoglou K, Probert L, Kontogeorgos G, etal. Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice. J Immunol 1997 158 438-445
2. Akiyama H, Arai T, Kondo H, etal. Cell mediators of inflammation in the Alzheimer disease brain. Alzheimer Dis Assoc Disord 2000 14 S47-S53
3. Akomolafe A, Beiser A, Meigs JB, etal. Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study. Arch Neurol 2006 63 1551-1555
4. Barnum SR, Jones JL, Muller-Ladner U, etal. Chronic complement C3 gene expression in the CNS of transgenic mice with astrocyte-targeted interleukin-6 expression. Glia 1996 18 107-117
5. Bierhaus A, Humpert PM, Nawroth PP. Linking stress to inflammation. Anesthesiol Clin 2006 24 325-340
6. Breitner JC. Inflammatory processes and antiinflammatory drugs in Alzheimer's disease: a current appraisal. Neurobiol Aging 1996 17 789-794
7. Dandona P, Aljada A, Bandyopadhyay A. Inflammation: the link between insulin resistance, obesity and diabetes. Trends Immunol 2004 25 4-7
8. Das S, Potter H. Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1. Neuron 1995 14 447-456
9. Ellman GL, Courtney KD, Andres VJ, etal. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961 7 88-95
10. Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer's disease. J Neuroimmunol 2007 184 69-91
11. Li L, Holscher C. Common pathological processes in Alzheimer disease and type 2 diabetes: a review. Brain Res Rev 2007 56 384-402
12. Li Y, Liu L, Kang J, etal. Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression. J Neurosci 2000 20 149-155
13. Lowry OH, Rosebrough NJ, Farr AL, etal. Protein measurement with the Folin phenol reagent. J Biol Chem 1951 193 265-275
14. Mackenzie IR. Postmortem studies of the effect of anti-inflammatory drugs on Alzheimer-type pathology and associated inflammation. Neurobiol Aging 2001 22 819-822
15. Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 1984 11 47-60
16. Nawroth PP, Rudofsky G, Humpert P. Have we understood diabetes? New tasks for diagnosis and therapy. Exp Clin Endocrinol Diabetes 2010 118 1-3
17. Ott A, Stolk RP, van Harskamp F, etal. Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology 1999 53 1937-1942
18. Rich JB, Rasmusson DX, Folstein MF, etal. Nonsteroidal anti-inflammatory drugs in Alzheimer's disease. Neurology 1995 45 51-55
19. Rogers J, Webster S, Lue LF, etal. Inflammation and Alzheimer's disease pathogenesis. Neurobiol Aging 1996 17 681-686
20. Sun MK, Alkon DL. Links between Alzheimer's disease and diabetes. Drugs Today (Barc) 2006 42 481-489
21. Temelkova-Kurktschiev T, Henkel E, Koehler C, etal. Subclinical inflammation in newly detected Type II diabetes and impaired glucose tolerance. Diabetologia 2002 45 151
22. van den Berg E, de Craen AJ, Biessels GJ, etal. The impact of diabetes mellitus on cognitive decline in the oldest of the old: a prospective population-based study. Diabetologia 2006 49 2015-2023
23. Wang T, Fu FH, Han B, etal. Aspirin attenuates cerebral ischemic injury in diabetic rats. Exp Clin Endocrinol Diabetes 2009 117 181-185
24. Wenk GL, Willard LB. The neural mechanisms underlying cholinergic cell death within the basal forebrain. Int J Dev Neurosci 1998 16 729-735
25. Whitmer RA. Type 2 diabetes and risk of cognitive impairment and dementia. Curr Neurol Neurosci Rep 2007 7 373-380