Opposing responses of apoptosis and autophagy to moderate compression in skeletal muscle

Acta Physiologica

Volumn 201, Issue 2, 2011, Pages 239-254

  Teng, B T ^a   Pei, X M ^a   Tam, E W ^a   Benzie, I F ^a   Siu, P M ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Bedsore; Caspase; Deep pressure ulcer; Programmed cell death

Indexed keywords

BECLIN 1; CASPASE 3; CASPASE 8; CASPASE 9; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DECUBITUS; DNA FRAGMENTATION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; HISTOLOGY; HISTOPATHOLOGY; HUMAN; IMMUNOBLOTTING; LABELING INDEX; MALE; MOLECULAR MECHANICS; MUSCLE CELL; MUSCLE DISEASE; MUSCLE TISSUE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; STATISTICAL SIGNIFICANCE; TIBIALIS ANTERIOR MUSCLE; TISSUE INJURY;

EID: 78651439524     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2010.02173.x     Document Type: Article

References (49)

1. Alway, S.E. & Siu, P.M. 2008. Nuclear apoptosis contributes to sarcopenia. Exerc Sport Sci Rev 36, 51-57.
2. Bass, M.J. & Phillips, L.G. 2007. Pressure sores. Curr Probl Surg 44, 101-143.
3. Black, J., Baharestani, M.M., Cuddigan, J., Dorner, B., Edsberg, L., Langemo, D., Posthauer, M.E., Ratliff, C. & Taler, G. 2007. National Pressure Ulcer Advisory Panel's updated pressure ulcer staging system. Adv Skin Wound Care 20, 269-274.
4. Bouten, C.V., Oomens, C.W., Baaijens, F.P. & Bader, D.L. 2003. The etiology of pressure ulcers: skin deep or muscle bound? Arch Phys Med Rehabil 84, 616-619.
5. Bronneberg, D., Spiekstra, S.W., Cornelissen, L.H., Oomens, C.W., Gibbs, S., Baaijens, F.P. & Bouten, C.V. 2007. Cytokine and chemokine release upon prolonged mechanical loading of the epidermis. Exp Dermatol 16, 567-573.
6. Brunet, A., Bonni, A., Zigmond, M.J., Lin, M.Z., Juo, P., Hu, L.S., Anderson, M.J., Arden, K.C., Blenis, J. & Greenberg, M.E. 1999. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96, 857-868.
7. Cornelissen, L.H., Bronneberg, D., Bader, D.L., Baaijens, F.P. & Oomens, C.W. 2009. The transport profile of cytokines in epidermal equivalents subjected to mechanical loading. Ann Biomed Eng 37, 1007-1018.
8. Djavaheri-Mergny, M., Maiuri, M.C. & Kroemer, G. 2010. Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene 29, 1717-1719.
9. Donnelly, J. 2005. Should we include deep tissue injury in pressure ulcer staging systems? The NPUAP debate. J Wound Care 14, 207-210.
10. Dupont-Versteegden, E.E. 2006. Apoptosis in skeletal muscle and its relevance to atrophy. World J Gastroenterol 12, 7463-7466.
11. Haidara, K., Marion, M., Gascon-Barre, M., Denizeau, F. & Averill-Bates, D.A. 2008. Implication of caspases and subcellular compartments in tert-butylhydroperoxide induced apoptosis. Toxicol Appl Pharmacol 229, 65-76.
12. Ichimura, Y., Kirisako, T., Takao, T., Satomi, Y., Shimonishi, Y., Ishihara, N., Mizushima, N., Tanida, I., Kominami, E., Ohsumi, M., Noda, T. & Ohsumi, Y. 2000. A ubiquitin-like system mediates protein lipidation. Nature 408, 488-492.
13. Klionsky, D.J. & Emr, S.D. 2000. Autophagy as a regulated pathway of cellular degradation. Science 290, 1717-1721.
14. Kwan, M.P., Tam, E.W., Lo, S.C., Leung, M.C. & Lau, R.Y. 2007. The time effect of pressure on tissue viability: investigation using an experimental rat model. Exp Biol Med (Maywood) 232, 481-487.
15. Lang, T., Schaeffeler, E., Bernreuther, D., Bredschneider, M., Wolf, D.H. & Thumm, M. 1998. Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole. EMBO J 17, 3597-3607.
16. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S.M., Ahmad, M., Alnemri, E.S. & Wang, X. 1997. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489.
17. Liang, X.H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H. & Levine, B. 1999. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402, 672-676.
18. Linder-Ganz, E. & Gefen, A. 2004. Mechanical compression-induced pressure sores in rat hindlimb: muscle stiffness, histology, and computational models. J Appl Physiol 96, 2034-2049.
19. Linder-Ganz, E., Engelberg, S., Scheinowitz, M. & Gefen, A. 2006. Pressure-time cell death threshold for albino rat skeletal muscles as related to pressure sore biomechanics. J Biomech 39, 2725-2732.
20. Maiuri, M.C., Zalckvar, E., Kimchi, A. & Kroemer, G. 2007. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8, 741-752.
21. Mammucari, C., Milan, G., Romanello, V., Masiero, E., Rudolf, R., Del Piccolo, P., Burden, S.J., Di Lisi, R., Sandri, C., Zhao, J., Goldberg, A.L., Schiaffino, S. & Sandri, M. 2007. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 6, 458-471.
22. Marzetti, E. & Leeuwenburgh, C. 2006. Skeletal muscle apoptosis, sarcopenia and frailty at old age. Exp Gerontol 41, 1234-1238.
23. Masiero, E. & Sandri, M. 2010. Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles. Autophagy 6, 307-309.
24. Masiero, E., Agatea, L., Mammucari, C., Blaauw, B., Loro, E., Komatsu, M., Metzger, D., Reggiani, C., Schiaffino, S. & Sandri, M. 2009. Autophagy is required to maintain muscle mass. Cell Metab 10, 507-515.
25. McMullen, C.A., Ferry, A.L., Gamboa, J.L., Andrade, F.H. & Dupont-Versteegden, E.E. 2009. Age-related changes of cell death pathways in rat extraocular muscle. Exp Gerontol 44, 420-425.
26. Mizushima, N. 2007. Autophagy: process and function. Genes Dev 21, 2861-2873.
27. Ogata, T., Oishi, Y., Higuchi, M. & Muraoka, I. 2010. Fasting-related autophagic response in slow- and fast-twitch skeletal muscle. Biochem Biophys Res Commun 394, 136-140.
28. O'Leary, M.F. & Hood, D.A. 2008. Effect of prior chronic contractile activity on mitochondrial function and apoptotic protein expression in denervated muscle. J Appl Physiol 105, 114-120.
29. O'Leary, M.F. & Hood, D.A. 2009. Denervation-induced oxidative stress and autophagy signaling in muscle. Autophagy 5, 230-231.
30. Pattingre, S., Tassa, A., Qu, X., Garuti, R., Liang, X.H., Mizushima, N., Packer, M., Schneider, M.D. & Levine, B. 2005. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122, 927-939.
31. Salzberg, C.A., Byrne, D.W., Cayten, C.G., van Niewerburgh, P., Murphy, J.G. & Viehbeck, M. 1996. A new pressure ulcer risk assessment scale for individuals with spinal cord injury. Am J Phys Med Rehabil 75, 96-104.
32. Siu, P.M. 2009. Muscle apoptotic response to denervation, disuse, and aging. Med Sci Sports Exerc 41, 1876-1886.
33. Siu, P.M. & Alway, S.E. 2005a. Age-related apoptotic responses to stretch-induced hypertrophy in quail slow-tonic skeletal muscle. Am J Physiol Cell Physiol 289, C1105-C1113.
34. Siu, P.M. & Alway, S.E. 2005b. Mitochondria-associated apoptotic signalling in denervated rat skeletal muscle. J Physiol 565, 309-323.
35. Siu, P.M. & Alway, S.E. 2005c. Subcellular responses of p53 and Id2 in fast and slow skeletal muscle in response to stretch-induced overload. J Appl Physiol 99, 1897-1904.
36. Siu, P.M. & Alway, S.E. 2006a. Aging alters the reduction of pro-apoptotic signaling in response to loading-induced hypertrophy. Exp Gerontol 41, 175-188.
37. Siu, P.M. & Alway, S.E. 2006b. Deficiency of the Bax gene attenuates denervation-induced apoptosis. Apoptosis 11, 967-981.
38. Siu, P.M. & Alway, S.E. 2009. Response and adaptation of skeletal muscle to denervation stress: the role of apoptosis in muscle loss. Front Biosci 14, 432-452.
39. Siu, P.M., Bryner, R.W., Murlasits, Z. & Alway, S.E. 2005. Response of XIAP, ARC, and FLIP apoptotic suppressors to 8 wk of treadmill running in rat heart and skeletal muscle. J Appl Physiol 99, 204-209.
40. Siu, P.M., Pistilli, E.E., Murlasits, Z. & Alway, S.E. 2006. Hindlimb unloading increases muscle content of cytosolic but not nuclear Id2 and p53 proteins in young adult and aged rats. J Appl Physiol 100, 907-916.
41. Siu, P.M., Tam, E.W., Teng, B.T., Pei, X.M., Ng, J.W., Benzie, I.F. & Mak, A.F. 2009. Muscle apoptosis is induced in pressure-induced deep tissue injury. J Appl Physiol 107, 1266-1275.
42. Stekelenburg, A., Oomens, C.W., Strijkers, G.J., Nicolay, K. & Bader, D.L. 2006. Compression-induced deep tissue injury examined with magnetic resonance imaging and histology. J Appl Physiol 100, 1946-1954.
43. Varfolomeev, E.E. & Ashkenazi, A. 2004. Tumor necrosis factor: an apoptosis JuNKie? Cell 116, 491-497.
44. Wenz, T., Rossi, S.G., Rotundo, R.L., Spiegelman, B.M. & Moraes, C.T. 2009. Increased muscle PGC-1 alpha expression protects from sarcopenia and metabolic disease during aging. Proc Natl Acad Sci USA 106, 20405-20410.
45. Williamson, D.L., Raue, U., Slivka, D.R. & Trappe, S. 2010. Resistance exercise, skeletal muscle FOXO3A, and 85-year-old women. J Gerontol A Biol Sci Med Sci 65, 335-343.
46. Wohlgemuth, S.E., Seo, A.Y., Marzetti, E., Lees, H.A. & Leeuwenburgh, C. 2009. Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise. Exp Gerontol 45, 138-148.
47. Woolsey, R.M. & McGarry, J.D. 1991. The cause, prevention, and treatment of pressure sores. Neurol Clin 9, 797-808.
48. Yuan, J. 1997. Transducing signals of life and death. Curr Opin Cell Biol 9, 247-251.
49. Zhao, J., Brault, J.J., Schild, A., Cao, P., Sandri, M., Schiaffino, S., Lecker, S.H. & Goldberg, A.L. 2007. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 6, 472-483.