The connexin 37 (1019c>T) gene polymorphism is associated with subclinical atherosclerosis in women with type 1 and 2 diabetes and in women with central obesity

Physiological Research

Volumn 59, Issue 6, 2010, Pages 1029-1032

  Pitha, J ^a   Hubacek J A ^a   Pithova P ^b  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^b UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

Author keywords

Ankle brachial indexwomen; Atherosclerosis; Central obesity; Connexin 37 gene; Diabetes mellitus

Indexed keywords

CONNEXIN 37; GAP JUNCTION PROTEIN;

ABDOMINAL OBESITY; ARTICLE; ATHEROSCLEROSIS; FEMALE; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; RISK FACTOR;

ATHEROSCLEROSIS; CONNEXINS; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; FEMALE; GENOTYPE; HUMANS; MIDDLE AGED; OBESITY, ABDOMINAL; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 78651432251     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. BOERMA M, FORSBERG L, VAN ZEIJL L, MORGENSTERN R, DE FAIRE U, LEMNE C, ERLINGE D, THULIN T, HONG Y, COTGREAVE IA: A genetic polymorphism in Connexin 37 as a prognostic marker for atherosclerotic plaque development. J Intern Med 246: 211-218, 1999.
2. BROCH M, RAMÍREZ R, AUGUET MT, ALCAIDE MJ, AGUILAR C, GARCIA-ESPANA A, RICHART C: Macrophages are novel sites of expression and regulation of retinol binding protein-4 (RBP4). Physiol Res 59: 299-303, 2010.
3. BURNIER L, FONTANA P, ANGELILLO-SCHERRER A, KWAK BR: Intercellular communication in atherosclerosis. Physiology (Bethesda) 24: 36-44, 2009.
4. COLLINGS A, ISLAM MS, JUONALA M, RONTU R, KÄHÖNEN M, HUTRI-KÄHÖNEN N, LAITINEN T, MARNIEMI J, VIIKARI JS, RAITAKARI OT, LEHTIMÄKI TJ: Associations between connexin37 gene polymorphism and markers of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns study. Atherosclerosis 195: 379-384, 2007.
5. HAN Y, XI S, ZHANG X, YAN C, YANG Y, KANG J: Association of connexin 37 gene polymorphisms with risk of coronary artery disease in northern Han Chinese. Cardiology 110: 260-265, 2008.
6. HIRASHIKI A, YAMADA Y, MURASE Y, SUZUKI Y, KATAOKA H, MORIMOTO Y, TAJIKA T, MUROHARA T, YOKOTA M: Association of gene polymorphisms with coronary artery disease in lowor high-risk subjects defined by conventional risk factors. J Am Coll Cardiol 42: 1429-1437, 2003.
7. HORAN PG, ALLEN AR, PATTERSON CC, SPENCE MS, MCGLINCHEY PG, MCKEOWN P: The connexin 37 gene polymorphism and coronary artery disease in Ireland. Heart 92: 395-396, 2006.
8. LANFEAR DE, JONES PG, MARSH S, CRESCI S, SPERTUS JA, MCLEOD HL: Connexin37 (GJA4) genotype predicts survival after an acute coronary syndrome. Am Heart J 154: 561-566, 2007.
9. MILICEVIC Z, RAZ I, BEATTIE SD, CAMPAIGNE BN, SARWAT S, GROMNIAK E, KOWALSKA I, GALIC E, TAN M, HANEFELD M: Natural history of cardiovascular disease in patients with diabetes: role of hyperglycemia. Diabetes Care 31 (Suppl 2): S155-S160, 2008.
10. MILLER SA, DYKES DD, POLESKY HF: A simple salting out procedure for DNA extraction from human nucleated cells. Nucleic Acid Res 16: 1215, 1988.
11. YAMADA Y, IZAWA H, ICHIHARA S, TAKATSU F, ISHIHARA H, HIRAYAMA H, SONE T, TANAKA M, YOKOTA M: Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. N Engl J Med 347: 1916-1923, 2002.
12. YEH HI, CHOU Y, LIU HF, CHANG SC, TSAI CH: Connexin 37 gene polymorphism and coronary artery disease in Taiwan. Int J Cardiol 81: 251-255, 2001.
13. WONG CW, CHRISTEN T, ROTH I, CHADJICHRISTOS CE, DEROUETTE JP, FOGLIA BF, CHANSON M, GOODENOUGH DA, KWAK BR: Connexin 37 protects against atherosclerosis by regulating monocyte adhesion. Nat Med 12: 950-954, 2006.