A genetic polymorphism in connexin 37 as a prognostic marker for atherosclerotic plaque development

Journal of Internal Medicine

Volumn 246, Issue 2, 1999, Pages 211-218

  Boerma, M ^a   Forsberg, L ^a   Van Zeijl, L ^a   Morgenstern, R ^a   De Faire, U ^b,c   Lemne, C ^c   Erlinge, D ^d   Thulin, T ^d   Hong, Y ^c   Cotgreave, Ian A ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Atherosclerosis; Connexin 37; Plaque; Polymorphism; Prognostic indicator

Indexed keywords

CONNEXIN 47; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ATHEROSCLEROTIC PLAQUE; DISEASE ASSOCIATION; ENDOTHELIUM CELL; EXPRESSED SEQUENCE TAG; GENETIC MARKER; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR;

ADULT; ALLELES; ARTERIOSCLEROSIS; BIOLOGICAL MARKERS; CAROTID STENOSIS; CASE-CONTROL STUDIES; CONNEXINS; DNA PRIMERS; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROGNOSIS; SEQUENCE ANALYSIS, DNA; SWEDEN; UP-REGULATION;

EID: 0032813517     PISSN: 09546820     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2796.1999.00564.x     Document Type: Article

References (22)

1. In: Gallin JI, Goldstein IM, Snyderman R, eds. Atherogenesis Inflammation: Basic Principles and Clinical Correlates, 2nd edn. 1992: New York: Raven Press, 1051-9.
2. Powell RJ, Cronenwett JL, Fillinger MF, Wagner RJ. Sampson LN. Endothelial cell modulation of smooth muscle cell morphology and organizational growth pattern. Ann Vasc Surg 1996; 10: 4-10.
3. Griendling KK, Alexander RW. Cellular biology of blood vessels. In: Hurst's the Heart. Schlant RC, Alexander RW, eds. New York: McGraw-Hill, 1993: 31-45.
4. Sosa-Melgarejo JA, Berry CL. Myoendothelial contacts in arteriolosclerosis. J Pathol 1992; 167: 235-9.
5. Griendling KK, Alexander RW. Endothelial control of the cardiovascular system: recent advances. FASEB J 1996; 10: 283-92.
6. Budunova IV. Alteration of gap junctional intercellular communication during carcinogenesis. Cancer J 1994; 7: 228-37.
7. Goodenough DA, Goliger JA, Paul DL. Connexins, connexons, and intercellular communication. Ann Rev Biochem 1996; 65: 475-502.
8. Yamasaki H. Gap junctional intercellular communication and carcinogenesis. Carcinogenesis 1990; 11: 1051-8.
9. Yotti LP, Chang CC, Trosko JE. Elimenation of metabolic cooperation in chinese hamster cells by tumour promoter. Science 1979; 206: 1089-91.
10. Murray AW, Fitzgerald DJ. Tumour promoters inhibit metabolic cooperation in co-cultures of epidermal and 3T3 cells. Biochem Biophys Res Comms 1979; 91: 395-401.
11. Sácz JC, Berthoud VM, Moreno AP, Spray DC. Multiplicity of controls in differentiated and undifferentiated cells and possible functional implications. Adv Second Messenger Phosphoprotein Research 1993; 27: 163-98.
12. Larson DM, Haudenschild CC, Beyer EC. Gap junction messenger RNA expression by vascular wall cells. Circulation Res 1990; 66: 1074-80.
13. Reed KE, Westphale EH, Larson, DM, Wang, H, Veensfra, RD, Beyer, EC. Molecular cloning and functional expression of human connexin 37 and endothelial cell gap junction protein. J Clin Investigations 1993; 91: 997-1004.
14. Van Rijen HVM, Kempen MJAV, Analbers LJS et al. Gap junctions in human umbilical cord endothelial cells contain multiple connexins. Am J Physiol 1997, 272 (Cell Physiol); 41: C117-C130.
15. Bruzzone R, Haeflinger J, Gimlich RL, Paul DL. Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins. Mol Biol Cell 1993; 4: 7-20.
16. Hu J, Cotgreave IA. Differential regulation of gap junctions by proinflammatory mediators in vitro. J Clin Investigation 1997; 99: 1-5.
17. Britz-Cunningham SH, Shah MM, Zuppan CW, Fletcher WH. Mutations of the connexin43 gap-junction gene in patients with heart malformations and defects of laterality. New England J Med 1995; 332: 1323-9.
18. Krutovskikh V, Mironov N, Yamasaki H. Human connexin 37 is polymorphic but not mutated in tumours. Carcinogenesis 1996; 17: 1761-3.
19. Richard G, Lin JP, Smith L et al. Linkage studies in crythrokeratodermias: fine mapping, genetic heterogeneity, and analysis of candidate genes. J Invest Dermatol 1997; 109: 666-71.
20. Lemne C, Jogestrand T, de Faire U. Carotid intima-media thickness and plaque in borderline hypertension. Stroke 1995; 26: 34-9.
21. Mercuri M, Tang R, Phillips M, Bond MG. Ultrasound protocol and quality control procedures in the European Lacidipine Study on Atherosclerosis (ELSA). Blood Pressure 1996; 4 s:20-3.
22. Dean AG, Dean JA, Columbier D et al. Info, version 6.0: A word processing. Database and Statistics program for public health on IBM-compatible microcomputers. Center for Disease Control and Prevention, Atlanta, Georgia, USA. 1995.