Adenovirus-mediated sphingomyelin synthase 2 increases atherosclerotic lesions in ApoE KO mice

Lipids in Health and Disease

Volumn 10, Issue , 2011, Pages

  Wang, Xiaogang ^a   Dong, Jibin ^a   Zhao, Yarui ^a   Li, Yue ^a   Wu, Manping ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; APOENZYME; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PHOSPHATIDYLCHOLINE; SPHINGOMYELIN; SPHINGOMYELIN SYNTHASE 2; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; APOLIPOPROTEIN E; LIPID; MEMBRANE PROTEIN; NERVE PROTEIN; PHOSPHOTRANSFERASE; RECOMBINANT PROTEIN; SGMS1 PROTEIN, HUMAN;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA ARCH; AORTA ATHEROSCLEROSIS; AORTA ROOT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME BLOOD LEVEL; MOUSE; NONHUMAN; TRIACYLGLYCEROL BLOOD LEVEL; VIRUS GENE; VIRUS RECOMBINANT; ANIMAL; AORTA; ATHEROSCLEROSIS; BIOSYNTHESIS; BLOOD; C57BL MOUSE; ENZYME ASSAY; FAT INTAKE; GENE VECTOR; GENETICS; HUMAN; LIVER; METABOLISM; MOUSE MUTANT; PATHOLOGY;

ADENOVIRIDAE; MUS;

ADENOVIRIDAE; ANIMALS; AORTA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; DIETARY FATS; ENZYME ASSAYS; GENETIC VECTORS; HUMANS; LIPIDS; LIVER; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; RECOMBINANT PROTEINS; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 78651402480     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-10-7     Document Type: Article

References (24)

1. Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice. MR Hojjati Z Li H Zhou S Tang C Huan E Ooi S Lu XC Jiang, J Biol Chem 2005 280 10284 9 10.1074/jbc.M412348200 15590644
2. Plasma sphingomyelin level as a risk factor for coronary artery disease. XC Jiang F Paultre TA Pearson RG Reed CK Francis M Lin L Berglund AR Tall, Arterioscler Thromb Vasc Biol 2000 20 2614 8 11116061
3. Changes in the phospholipid composition of the arterial cell can result in severe atherosclerotic lesions. FA Kummerow LS Cook E Wasowicz H Jelen, J Nutr Biochem 2001 12 602 7 10.1016/S0955-2863(01)00181-4 12031266
4. Development of the lipid-rich core in human atherosclerosis. JR Guyton KF Klemp, Arterioscler Thromb Vasc Biol 1996 16 4 11 8548424
5. Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity withmammalian sphingomyelinase. Ts Jeong SL Schissel I Tabas HJ Pownall AR Tall X Jiang, J Clin Invest 1998 101 905 12 10.1172/JCI870 9466986
6. Apolipoprotein E and the apolipoprotein E-deficient mouse. AS Plump JL Breslow, Annu Rev Nutr 1995 15 495 518 10.1146/annurev.nu.15.070195.002431 8527231
7. Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice. TS Park RL Panek SB Mueller JC Hanselman WS Rosebury AW Robertson EK Kindt R Homan SK Karathanasis MD Rekhter, Circulation 2004 30 3465 71 10.1161/01.CIR.0000148370.60535.22 (Pubitemid 39602225)
8. Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice. J Dong J Liu B Lou Z Li X Ye M Wu XC Jiang, J Lipid Res 2006 47 1307 14 10.1194/jlr.M600040-JLR200 16508036
9. SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis. T Ding Z Li T Hailemariam S Mukherjee FR Maxfield MP Wu XC Jiang, J Lipid Res 2008 49 376 85 10.1194/jlr.M700401-JLR200 17982138
10. Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease. A Schlitt S Blankenberg D Yan H von Gizycki M Buerke K Werdan C Bickel KJ Lackner J Meyer HJ Rupprecht XC Jiang, Nutr Metab(Lond) 2006 3 5 10.1186/1743-7075-3-5 16396678
11. The response-to-retention hypothesis of atherogenesis reinforced. KJ Williams I Tabas, Curr Opin Lipidol 1998 9 471 4 10.1097/00041433-199810000- 00012 9812202
12. Lipid accumulation in rabbit aortic intima 2 hours after bolus infusion of low density lipoprotein. A deep-etch and immunolocalization study of ultrarapidly frozen tissue. PF Nievelstein AM Fogelman G Mottino JS Frank, Arterioscler Thromb 1991 11 1795 805 1931881
13. Sphingomyelin synthase as a potential target for D609-induced apoptosis in U937 human monocytic leukemia cells. A Meng C Luberto P Meier A Bai X Yang YA Hannun D Zhou, Exp Cell Res 2004 292 385 92 10.1016/j.yexcr.2003.10.001 14697345
14. Composition of phospholipids and of phospholipid fatty acids of human plasma. GB Phillips JT Dodge, J Lipid Res 1967 8 676 81 6057496
15. Plasma sphingomyelin level as a risk factor for coronary artery disease. XC Jiang F Paultre TA Pearson RG Reed CK Francis M Lin L Berglund AR Tall, Arterioscler Thromb Vasc Biol 2000 20 2614 8 11116061
16. Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein. Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins. SL Schissel J Tweedie-Hardman JH Rapp G Graham KJ Williams I Tabas, J Clin Invest 1996 98 1455 64 10.1172/JCI118934 8823312
17. Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice. J Liu H Zhang Z Li TK Hailemariam M Chakraborty K Jiang D Qiu HH Bui DA Peake MS Kuo R Wadgaonkar G Cao XC Jiang, Arterioscler Thromb Vasc Biol 2009 29 850 6 10.1161/ATVBAHA.109.185223 19286635
18. Role of newly synthesized fibronectin in vascular smooth muscle cell migration on matrix-metalloproteinase-degraded collagen. E Stringa D White RS Tuan V Knauper J Gavrilovic, Biochem Soc Trans 2002 30 102 11 10.1042/BST0300102 12023834
19. Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes. H Kai H Ikeda H Yasukawa M Kai Y Seki F Kuwahara T Ueno K Sugi T Imaizumi, J Am Coll Cardiol 1998 32 368 72 10.1016/S0735-1097(98)00250-2 9708462
20. Functional rafts in cell membranes. K Simons E Ikonen, Nature 1997 387 569 72 10.1038/42408 9177342
21. Lipid sorting in epithelial cells. K Simons G van Meer, Biochemistry 1988 27 6197 202 10.1021/bi00417a001 3064805
22. Localization and regulation of SR-BI in membrane rafts of HepG2 cells. D Rhainds P Bourgeois G Bourret K Huard L Falstrault L Brissette, J Cell Sci 2004 117 3095 105 10.1242/jcs.01182 15226391
23. Cholesterol depletion induces PKA-mediated basolateral-to-apical transcytosis of the scavenger receptor class B type I in MDCK cells. PV Burgos C Klattenhoff E de la Fuente A Rigotti A Gonzlez, Proc Natl Acad Sci USA 2004 101 3845 50 10.1073/pnas.0400295101 15007173
24. Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein. Y Peng W Akmentin MA Connelly S Lund-Katz MC Phillips DL Williams, Mol Biol Cell 2004 15 384 96 10.1091/mbc.E03-06-0445 14528013