Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibition

Oncogene

Volumn 30, Issue 2, 2011, Pages 153-166

  Chen, T H ^a   Chan, P C ^a   Chen, C L ^a   Chen, H C ^a,b  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

autoinhibition; FAK; FERM; Met; RTK

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; FOCAL ADHESION KINASE; PHOSPHATIDYLINOSITIDE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; SCATTER FACTOR RECEPTOR; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

AMINO ACID SEQUENCE; ANIMALS; CYTOSKELETAL PROTEINS; DOGS; ENZYME ACTIVATION; FOCAL ADHESION KINASE 1; HUMANS; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MET; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; TYROSINE;

EID: 78651401021     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.398     Document Type: Article

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