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Volumn 28, Issue 1, 2011, Pages 88-98

Looking to the future of research in pediatric anxiety disorders

Author keywords

anxiety disorders; biomarkers; clinical trials; developmental neuroscience; healthcare policy

Indexed keywords

BIOLOGICAL MARKER; GEFITINIB; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SEROTONIN UPTAKE INHIBITOR;

EID: 78651400506     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.20754     Document Type: Review
Times cited : (16)

References (111)
  • 1
    • 34948900832 scopus 로고    scopus 로고
    • Preschool psychopathology: Lessons for the lifespan
    • Angold A, Egger HL,. Preschool psychopathology: lessons for the lifespan. J Child Psychol Psychiatry 2007; 48: 961-966.
    • (2007) J Child Psychol Psychiatry , vol.48 , pp. 961-966
    • Angold, A.1    Egger, H.L.2
  • 3
    • 24944435437 scopus 로고    scopus 로고
    • The developmental epidemiology of anxiety disorders: Phenomenology, prevalence, and comorbidity
    • vii
    • Costello EJ, Egger HL, Angold A,. The developmental epidemiology of anxiety disorders: phenomenology, prevalence, and comorbidity. Child Adolesc Psychiatr Clin N Am 2005; 14: 631-648, vii.
    • (2005) Child Adolesc Psychiatr Clin N Am , vol.14 , pp. 631-648
    • Costello, E.J.1    Egger, H.L.2    Angold, A.3
  • 4
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication
    • DOI 10.1001/archpsyc.62.6.593
    • Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE,. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005; 62: 593-602. (Pubitemid 40973434)
    • (2005) Archives of General Psychiatry , vol.62 , Issue.6 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Merikangas, K.R.5    Walters, E.E.6
  • 6
    • 59649109483 scopus 로고    scopus 로고
    • Translating scientific opportunity into public health impact: A strategic plan for research on mental illness
    • Insel TR,. Translating scientific opportunity into public health impact: a strategic plan for research on mental illness. Arch Gen Psychiatry 2009; 66 (2): 128-133.
    • (2009) Arch Gen Psychiatry , vol.66 , Issue.2 , pp. 128-133
    • Insel, T.R.1
  • 7
    • 77955700847 scopus 로고    scopus 로고
    • Early life programming and neurodevelopmental disorders
    • Bale TL, Baram TZ, Brown AS, et al. Early life programming and neurodevelopmental disorders. Biol Psychiatry 2010; 68: 314-319.
    • (2010) Biol Psychiatry , vol.68 , pp. 314-319
    • Bale, T.L.1    Baram, T.Z.2    Brown, A.S.3
  • 9
    • 57649122353 scopus 로고    scopus 로고
    • Challenges in developing novel treatments for childhood disorders: Lessons from research on anxiety
    • Pine DS, Helfinstein SM, Bar-Haim Y, Nelson E, Fox NA,. Challenges in developing novel treatments for childhood disorders: lessons from research on anxiety. Neuropsychopharmacology 2009; 34: 213-228.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 213-228
    • Pine, D.S.1    Helfinstein, S.M.2    Bar-Haim, Y.3    Nelson, E.4    Fox, N.A.5
  • 10
    • 33748286746 scopus 로고    scopus 로고
    • Clinical research at a crossroads: The NIH roadmap
    • Zerhouni EA,. Clinical research at a crossroads: the NIH roadmap. J Investig Med 2006; 54: 171-173.
    • (2006) J Investig Med , vol.54 , pp. 171-173
    • Zerhouni, E.A.1
  • 12
    • 0037021528 scopus 로고    scopus 로고
    • Integrating quality into the cycle of therapeutic development
    • Califf RM, Peterson ED, Gibbons RJ, et al. Integrating quality into the cycle of therapeutic development. J Am Coll Cardiol 2002; 40: 1895-1901.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 1895-1901
    • Califf, R.M.1    Peterson, E.D.2    Gibbons, R.J.3
  • 13
    • 56149106726 scopus 로고    scopus 로고
    • Recommendations for clinical decision support deployment: Synthesis of a roundtable of medical directors of information systems
    • Jenders RA, Osheroff JA, Sittig DF, Pifer EA, Teich JM,. Recommendations for clinical decision support deployment: synthesis of a roundtable of medical directors of information systems. AMIA Annu Symp Proc 2007; 359-363.
    • (2007) AMIA Annu Symp Proc , pp. 359-363
    • Jenders, R.A.1    Osheroff, J.A.2    Sittig, D.F.3    Pifer, E.A.4    Teich, J.M.5
  • 14
    • 77649234756 scopus 로고    scopus 로고
    • How to improve R&D productivity: The pharmaceutical industry's grand challenge
    • Paul SM, Mytelka DS, Dunwiddie CT, et al. How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nat Rev Drug Discov 2010; 9: 203-214.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 203-214
    • Paul, S.M.1    Mytelka, D.S.2    Dunwiddie, C.T.3
  • 16
    • 73449101512 scopus 로고    scopus 로고
    • Lessons from 60 years of pharmaceutical innovation
    • Munos B,. Lessons from 60 years of pharmaceutical innovation. Nat Rev Drug Discov 2009; 8: 959-968.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 959-968
    • Munos, B.1
  • 17
    • 77952571701 scopus 로고    scopus 로고
    • The perfect storm: CNS drug development in trouble
    • Nierenberg AA,. The perfect storm: CNS drug development in trouble. CNS Spectr 2010; 15: 282-283.
    • (2010) CNS Spectr , vol.15 , pp. 282-283
    • Nierenberg, A.A.1
  • 18
    • 57649120069 scopus 로고    scopus 로고
    • NIMH initiatives to facilitate collaborations among industry, academia, and government for the discovery and clinical testing of novel models and drugs for psychiatric disorders
    • Brady LS, Winsky L, Goodman W, Oliveri ME, Stover E,. NIMH initiatives to facilitate collaborations among industry, academia, and government for the discovery and clinical testing of novel models and drugs for psychiatric disorders. Neuropsychopharmacology 2009; 34: 229-243.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 229-243
    • Brady, L.S.1    Winsky, L.2    Goodman, W.3    Oliveri, M.E.4    Stover, E.5
  • 20
    • 63849127883 scopus 로고    scopus 로고
    • The future of psychotherapy for mentally ill children and adolescents
    • March JS,. The future of psychotherapy for mentally ill children and adolescents. J Child Psychol Psychiatry 2009; 50: 170-179.
    • (2009) J Child Psychol Psychiatry , vol.50 , pp. 170-179
    • March, J.S.1
  • 21
    • 33645100012 scopus 로고    scopus 로고
    • Child and adolescent psychopharmacology in the new millennium: A workshop for academia, industry, and government
    • DeVeaugh-Geiss J, March J, Shapiro M, et al. Child and adolescent psychopharmacology in the new millennium: a workshop for academia, industry, and government. J Am Acad Child Adolesc Psychiatry 2006; 45: 261-270.
    • (2006) J Am Acad Child Adolesc Psychiatry , vol.45 , pp. 261-270
    • Deveaugh-Geiss, J.1    March, J.2    Shapiro, M.3
  • 22
    • 58649105068 scopus 로고    scopus 로고
    • A clinical review of outcomes of the multimodal treatment study of children with attention-deficit/hyperactivity disorder (MTA)
    • Murray DW, Arnold LE, Swanson J, et al. A clinical review of outcomes of the multimodal treatment study of children with attention-deficit/hyperactivity disorder (MTA). Curr Psychiatry Rep 2008; 10: 424-431.
    • (2008) Curr Psychiatry Rep , vol.10 , pp. 424-431
    • Murray, D.W.1    Arnold, L.E.2    Swanson, J.3
  • 23
    • 6944229468 scopus 로고    scopus 로고
    • Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: The Pediatric OCD Treatment Study (POTS) randomized controlled trial
    • POTS
    • POTS. Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: the Pediatric OCD Treatment Study (POTS) randomized controlled trial. Jama 2004; 292: 1969-1976.
    • (2004) Jama , vol.292 , pp. 1969-1976
  • 24
  • 25
    • 70349642663 scopus 로고    scopus 로고
    • Clinical messages from the Treatment for Adolescents with Depression Study (TADS)
    • March JS, Vitiello B,. Clinical messages from the Treatment for Adolescents With Depression Study (TADS). Am J Psychiatry 2009; 166: 1118-1123.
    • (2009) Am J Psychiatry , vol.166 , pp. 1118-1123
    • March, J.S.1    Vitiello, B.2
  • 26
    • 58149083708 scopus 로고    scopus 로고
    • Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety
    • Walkup JT, Albano AM, Piacentini J, et al. Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety. N Engl J Med 2008; 359: 2753-2766.
    • (2008) N Engl J Med , vol.359 , pp. 2753-2766
    • Walkup, J.T.1    Albano, A.M.2    Piacentini, J.3
  • 28
    • 63449090101 scopus 로고    scopus 로고
    • A pragmatic-explanatory continuum indicator summary (PRECIS): A tool to help trial designers
    • Thorpe KE, Zwarenstein M, Oxman AD, et al. A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. J Clin Epidemiol 2009; 62: 464-475.
    • (2009) J Clin Epidemiol , vol.62 , pp. 464-475
    • Thorpe, K.E.1    Zwarenstein, M.2    Oxman, A.D.3
  • 29
    • 0033741912 scopus 로고    scopus 로고
    • Anxiety as a predictor and outcome variable in the Multimodal Treatment Study of Children with ADHD (MTA)
    • March JS, Swanson JM, Arnold L, et al. Anxiety as a predictor and outcome variable in the Multimodal Treatment Study of Children with ADHD (MTA). Journal of Abnormal Child Psychology 2000; 28: 527-541.
    • (2000) Journal of Abnormal Child Psychology , vol.28 , pp. 527-541
    • March, J.S.1    Swanson, J.M.2    Arnold, L.3
  • 30
    • 78651411316 scopus 로고    scopus 로고
    • Treating Obsessive-Compulsive Disorder in Children and Adolescents
    • Antony M.M., Purdon C., Summerfeldt L.J., editors. DC, US: American Psychological Association
    • Franklin ME, March JS, Garcia A., Treating Obsessive-Compulsive Disorder in Children and Adolescents. In:, Antony MM, Purdon C, Summerfeldt LJ, editors. Psychological treatment of obsessive compulsive disorders: Fundamentals and beyond. DC, US: American Psychological Association; 2007: 253-266.
    • (2007) Psychological Treatment of Obsessive Compulsive Disorders: Fundamentals and beyond , pp. 253-266
    • Franklin, M.E.1    March, J.S.2    Garcia, A.3
  • 31
    • 10144220645 scopus 로고    scopus 로고
    • Medication treatment strategies in the MTA Study: Relevance to clinicians and researchers
    • Greenhill LL, Abikoff HB, Arnold LE, et al. Medication treatment strategies in the MTA Study: relevance to clinicians and researchers. J Am Acad Child Adolesc Psychiatry 1996; 35: 1304-1313.
    • (1996) J Am Acad Child Adolesc Psychiatry , vol.35 , pp. 1304-1313
    • Greenhill, L.L.1    Abikoff, H.B.2    Arnold, L.E.3
  • 32
    • 0042783158 scopus 로고    scopus 로고
    • Treatment for Adolescents with Depression Study (TADS): Rationale, design, and methods
    • Team T,. Treatment for Adolescents With Depression Study (TADS): rationale, design, and methods. J Am Acad Child Adolesc Psychiatry 2003; 42: 531-542.
    • (2003) J Am Acad Child Adolesc Psychiatry , vol.42 , pp. 531-542
    • Team, T.1
  • 33
    • 0030935980 scopus 로고    scopus 로고
    • The need for large-scale randomized evidence
    • Baigent C,. The need for large-scale randomized evidence. Br J Clin Pharmacol 1997; 43: 349-353.
    • (1997) Br J Clin Pharmacol , vol.43 , pp. 349-353
    • Baigent, C.1
  • 34
    • 3242774819 scopus 로고    scopus 로고
    • Cognitive-Behavioral Psychotherapy for Anxiety and Depressive Disorders in Children and Adolescents: An Evidence-Based Medicine Review
    • Compton SN, March JS, Brent D, Albano AM, Weersing R, Curry J,. Cognitive-Behavioral Psychotherapy for Anxiety and Depressive Disorders in Children and Adolescents: An Evidence-Based Medicine Review. J Am Acad Child Adolesc Psychiatry 2004; 43: 930-959.
    • (2004) J Am Acad Child Adolesc Psychiatry , vol.43 , pp. 930-959
    • Compton, S.N.1    March, J.S.2    Brent, D.3    Albano, A.M.4    Weersing, R.5    Curry, J.6
  • 35
    • 35948965640 scopus 로고    scopus 로고
    • Pharmacotherapy for anxiety disorders in children and adolescents: An evidence-based medicine review
    • 592, 594-598
    • Compton SN, Kratochvil CJ, March JS,. Pharmacotherapy for anxiety disorders in children and adolescents: an evidence-based medicine review. Pediatr Ann 2007; 36: 586-590, 592, 594-598.
    • (2007) Pediatr Ann , vol.36 , pp. 586-590
    • Compton, S.N.1    Kratochvil, C.J.2    March, J.S.3
  • 36
    • 70349157301 scopus 로고    scopus 로고
    • Integrating research on development and fear learning: A vision for clinical neuroscience?
    • Pine DS,. Integrating research on development and fear learning: a vision for clinical neuroscience? Depress Anxiety 2009; 26: 775-779.
    • (2009) Depress Anxiety , vol.26 , pp. 775-779
    • Pine, D.S.1
  • 37
    • 18144363587 scopus 로고    scopus 로고
    • Developmental neurobiology and clinical disorders: Lost in translation?
    • Levitt P,. Developmental neurobiology and clinical disorders: lost in translation? Neuron 2005; 46: 407-412.
    • (2005) Neuron , vol.46 , pp. 407-412
    • Levitt, P.1
  • 38
    • 0036615456 scopus 로고    scopus 로고
    • An integrative, multidisciplinary approach to the study of brain-behavior relations in the context of typical and atypical development
    • Nelson CA, Bloom FE, Cameron JL, Amaral D, Dahl RE, Pine D,. An integrative, multidisciplinary approach to the study of brain-behavior relations in the context of typical and atypical development. Dev Psychopathol 2002; 14: 499-520.
    • (2002) Dev Psychopathol , vol.14 , pp. 499-520
    • Nelson, C.A.1    Bloom, F.E.2    Cameron, J.L.3    Amaral, D.4    Dahl, R.E.5    Pine, D.6
  • 39
    • 36549042579 scopus 로고    scopus 로고
    • From animal models to model animals
    • Insel TR,. From animal models to model animals. Biol Psychiatry 2007; 62: 1337-1339.
    • (2007) Biol Psychiatry , vol.62 , pp. 1337-1339
    • Insel, T.R.1
  • 40
    • 0037187193 scopus 로고    scopus 로고
    • Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult
    • Gross C, Zhuang X, Stark K, et al. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature 2002; 416: 396-400.
    • (2002) Nature , vol.416 , pp. 396-400
    • Gross, C.1    Zhuang, X.2    Stark, K.3
  • 41
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • Caspi A, Sugden K, Moffitt TE, et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301: 386-389.
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3
  • 42
    • 33847753969 scopus 로고    scopus 로고
    • Neurodevelopmental sequelae of postnatal maternal care in rodents: Clinical and research implications of molecular insights
    • Kaffman A, Meaney MJ,. Neurodevelopmental sequelae of postnatal maternal care in rodents: clinical and research implications of molecular insights. J Child Psychol Psychiatry 2007; 48: 224-244.
    • (2007) J Child Psychol Psychiatry , vol.48 , pp. 224-244
    • Kaffman, A.1    Meaney, M.J.2
  • 43
    • 33748964997 scopus 로고    scopus 로고
    • Therapeutic potential of RNA interference for neurological disorders
    • Sah DW,. Therapeutic potential of RNA interference for neurological disorders. Life Sci 2006; 79: 1773-1780.
    • (2006) Life Sci , vol.79 , pp. 1773-1780
    • Sah, D.W.1
  • 44
    • 33947112255 scopus 로고    scopus 로고
    • New potential leads in the biology and treatment of attention deficit-hyperactivity disorder
    • Casey BJ, Nigg JT, Durston S,. New potential leads in the biology and treatment of attention deficit-hyperactivity disorder. Curr Opin Neurol 2007; 20: 119-124.
    • (2007) Curr Opin Neurol , vol.20 , pp. 119-124
    • Casey, B.J.1    Nigg, J.T.2    Durston, S.3
  • 46
    • 57649116333 scopus 로고    scopus 로고
    • Bridging bench and practice: Translational research for schizophrenia and other psychotic disorders
    • Wang PS, Heinssen R, Oliveri M, Wagner A, Goodman W,. Bridging bench and practice: translational research for schizophrenia and other psychotic disorders. Neuropsychopharmacology 2009; 34: 204-212.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 204-212
    • Wang, P.S.1    Heinssen, R.2    Oliveri, M.3    Wagner, A.4    Goodman, W.5
  • 47
    • 33749842353 scopus 로고    scopus 로고
    • The National Institutes of Health Blueprint for Neuroscience Research
    • Baughman RW, Farkas R, Guzman M, Huerta MF,. The National Institutes of Health Blueprint for Neuroscience Research. J Neurosci 2006; 26: 10329-10331.
    • (2006) J Neurosci , vol.26 , pp. 10329-10331
    • Baughman, R.W.1    Farkas, R.2    Guzman, M.3    Huerta, M.F.4
  • 48
    • 67650146986 scopus 로고    scopus 로고
    • NIH program to boost pipeline for drugs to treat rare and neglected diseases
    • Kuehn BM,. NIH program to boost pipeline for drugs to treat rare and neglected diseases. JAMA 2009; 302: 133-134.
    • (2009) JAMA , vol.302 , pp. 133-134
    • Kuehn, B.M.1
  • 49
    • 58149092896 scopus 로고    scopus 로고
    • NIH assistance for new therapeutic development: NIH-RAID pilot program
    • Badman D,. NIH assistance for new therapeutic development: NIH-RAID pilot program. Journal of Commercial Biotechnology 2009; 15: 12-15.
    • (2009) Journal of Commercial Biotechnology , vol.15 , pp. 12-15
    • Badman, D.1
  • 50
    • 33748062359 scopus 로고    scopus 로고
    • Clinical and translational science awards: A framework for a national research agenda
    • Zerhouni EA, Alving B,. Clinical and translational science awards: a framework for a national research agenda. Transl Res 2006; 148: 4-5.
    • (2006) Transl Res , vol.148 , pp. 4-5
    • Zerhouni, E.A.1    Alving, B.2
  • 51
    • 77949262357 scopus 로고    scopus 로고
    • The role of academic health science systems in the transformation of medicine
    • .;()
    • Dzau VJ, Ackerly DC, Sutton-Wallace P, et al. The role of academic health science systems in the transformation of medicine. Lancet 2010; 375 (9718): 949-953.
    • (2010) Lancet , vol.375 , Issue.9718 , pp. 949-953
    • Dzau, V.J.1    Ackerly, D.C.2    Sutton-Wallace, P.3
  • 53
    • 59349088323 scopus 로고    scopus 로고
    • Future developments of medical informatics from the viewpoint of networked clinical research. Interoperability and integration
    • Ohmann C, Kuchinke W,. Future developments of medical informatics from the viewpoint of networked clinical research. Interoperability and integration. Methods Inf Med 2009; 48: 45-54.
    • (2009) Methods Inf Med , vol.48 , pp. 45-54
    • Ohmann, C.1    Kuchinke, W.2
  • 54
    • 32844472127 scopus 로고    scopus 로고
    • Cure therapeutics and strategic prevention: Raising the bar for mental health research
    • Insel TR, Scolnick EM,. Cure therapeutics and strategic prevention: raising the bar for mental health research. Mol Psychiatry 2006; 11 (1): 11-17.
    • (2006) Mol Psychiatry , vol.11 , Issue.1 , pp. 11-17
    • Insel, T.R.1    Scolnick, E.M.2
  • 56
    • 57649139354 scopus 로고    scopus 로고
    • Pharmacogenomics: The promise of personalized medicine for CNS disorders
    • de Leon J,. Pharmacogenomics: the promise of personalized medicine for CNS disorders. Neuropsychopharmacology 2009; 34: 159-172.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 159-172
    • De Leon, J.1
  • 57
    • 78651390691 scopus 로고    scopus 로고
    • Systems Biology
    • ScienceMag.org
    • ScienceMag.org. Systems Biology. Science 2002; 295 (5560).
    • (2002) Science , vol.295 , Issue.5560
  • 58
    • 47749098274 scopus 로고    scopus 로고
    • How can we realize the promise of personalized antidepressant medicines?
    • Holsboer F,. How can we realize the promise of personalized antidepressant medicines? Nat Rev Neurosci 2008; 9 (8): 638-646.
    • (2008) Nat Rev Neurosci , vol.9 , Issue.8 , pp. 638-646
    • Holsboer, F.1
  • 59
    • 35348874847 scopus 로고    scopus 로고
    • Personalized medicine in the era of genomics
    • Burke W, Psaty BM,. Personalized medicine in the era of genomics. JAMA 2007; 298: 1682-1684.
    • (2007) JAMA , vol.298 , pp. 1682-1684
    • Burke, W.1    Psaty, B.M.2
  • 62
    • 45549083080 scopus 로고    scopus 로고
    • Francis Collins interview. Departing U.S. genome institute director takes stock of personalized medicine. Interview by Jocelyn Kaiser
    • Collins F,. Francis Collins interview. Departing U.S. genome institute director takes stock of personalized medicine. Interview by Jocelyn Kaiser. Science 2008; 320: 1272.
    • (2008) Science , vol.320 , pp. 1272
    • Collins, F.1
  • 63
    • 73449126583 scopus 로고    scopus 로고
    • Developing tools for stratified medicine
    • Hughes B,. Developing tools for stratified medicine. Nat Rev Drug Discov 2009; 8: 919-920.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 919-920
    • Hughes, B.1
  • 64
    • 33947712686 scopus 로고    scopus 로고
    • Stratified medicine: Strategic and economic implications of combining drugs and clinical biomarkers
    • Trusheim MR, Berndt ER, Douglas FL,. Stratified medicine: strategic and economic implications of combining drugs and clinical biomarkers. Nat Rev Drug Discov 2007; 6: 287-293.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 287-293
    • Trusheim, M.R.1    Berndt, E.R.2    Douglas, F.L.3
  • 66
    • 45049084923 scopus 로고    scopus 로고
    • Opportunities and challenges of psychiatric drug discovery: Roles for scientists in academic, industry, and government settings
    • Conn P, Roth B,. Opportunities and challenges of psychiatric drug discovery: roles for scientists in academic, industry, and government settings. Neuropsychopharmacology 2008; 33: 2048-2060.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2048-2060
    • Conn, P.1    Roth, B.2
  • 67
    • 34347212482 scopus 로고    scopus 로고
    • Building a pharmacological lexicon: Small molecule discovery in academia
    • Lazo JS, Brady LS, Dingledine R,. Building a pharmacological lexicon: small molecule discovery in academia. Mol Pharmacol 2007; 72: 1-7.
    • (2007) Mol Pharmacol , vol.72 , pp. 1-7
    • Lazo, J.S.1    Brady, L.S.2    Dingledine, R.3
  • 69
    • 62649149933 scopus 로고    scopus 로고
    • Drug-diagnostic codevelopment strategies: FDA and industry dialog at the 4th FDA/DIA/PhRMA/PWG/BIO Pharmacogenomics Workshop
    • Hinman L, Spear B, Tsuchihashi Z, et al. Drug-diagnostic codevelopment strategies: FDA and industry dialog at the 4th FDA/DIA/PhRMA/PWG/BIO Pharmacogenomics Workshop. Pharmacogenomics 2009; 10: 127-136.
    • (2009) Pharmacogenomics , vol.10 , pp. 127-136
    • Hinman, L.1    Spear, B.2    Tsuchihashi, Z.3
  • 70
    • 57649121825 scopus 로고    scopus 로고
    • Metabolomics: A global biochemical approach to the study of central nervous system diseases
    • Kaddurah-Daouk R, Krishnan KR,. Metabolomics: a global biochemical approach to the study of central nervous system diseases. Neuropsychopharmacology 2009; 34: 173-186.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 173-186
    • Kaddurah-Daouk, R.1    Krishnan, K.R.2
  • 71
    • 77955704022 scopus 로고    scopus 로고
    • Integrating ADNI results into Alzheimer's disease drug development programs
    • Cummings JL,. Integrating ADNI results into Alzheimer's disease drug development programs. Neurobiol Aging 2010; 31 (8): 1481-1492.
    • (2010) Neurobiol Aging , vol.31 , Issue.8 , pp. 1481-1492
    • Cummings, J.L.1
  • 72
    • 34248324435 scopus 로고    scopus 로고
    • Cortical morphology in children and adolescents with different apolipoprotein e gene polymorphisms: An observational study
    • Shaw P, Lerch JP, Pruessner JC, et al. Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study. Lancet Neurol 2007; 6: 494-500.
    • (2007) Lancet Neurol , vol.6 , pp. 494-500
    • Shaw, P.1    Lerch, J.P.2    Pruessner, J.C.3
  • 73
    • 77951776829 scopus 로고    scopus 로고
    • Alzheimer's disease: Strategies for disease modification
    • Citron M,. Alzheimer's disease: strategies for disease modification. Nat Rev Drug Discov 2010; 9: 387-398.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 387-398
    • Citron, M.1
  • 74
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V, Nestler EJ,. The molecular neurobiology of depression. Nature 2008; 455 (7215): 894-902.
    • (2008) Nature , vol.455 , Issue.7215 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 75
    • 67650624058 scopus 로고    scopus 로고
    • Biomarkers in clinical drug development
    • Gobburu JV,. Biomarkers in clinical drug development. Clin Pharmacol Ther 2009; 86: 26-27.
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 26-27
    • Gobburu, J.V.1
  • 76
    • 38349160711 scopus 로고    scopus 로고
    • The Biomarkers Consortium: On the critical path of drug discovery
    • Altar CA,. The Biomarkers Consortium: on the critical path of drug discovery. Clin Pharmacol Ther 2008; 83: 361-364.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 361-364
    • Altar, C.A.1
  • 77
    • 67650637670 scopus 로고    scopus 로고
    • Biomarkers: Principles, policies, and practice
    • Wagner JA,. Biomarkers: principles, policies, and practice. Clin Pharmacol Ther 2009; 86: 3-7.
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 3-7
    • Wagner, J.A.1
  • 78
    • 67650639088 scopus 로고    scopus 로고
    • Chutes and ladders on the critical path: Comparative effectiveness, product value, and the use of biomarkers in drug development
    • Woodcock J,. Chutes and ladders on the critical path: comparative effectiveness, product value, and the use of biomarkers in drug development. Clin Pharmacol Ther 2009; 86: 12-14.
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 12-14
    • Woodcock, J.1
  • 79
    • 77950519413 scopus 로고    scopus 로고
    • NIH encourages translational collaboration with industry
    • Wadman M,. NIH encourages translational collaboration with industry. Nat Rev Drug Discov 2010; 9: 255-256.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 255-256
    • Wadman, M.1
  • 80
    • 72849113611 scopus 로고    scopus 로고
    • Biomarker qualification via public-private partnerships
    • Eck SL, Paul SM,. Biomarker qualification via public-private partnerships. Clin Pharmacol Ther 2010; 87: 21-23.
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 21-23
    • Eck, S.L.1    Paul, S.M.2
  • 82
    • 77953638156 scopus 로고    scopus 로고
    • A call for sharing: Adapting pharmaceutical research to new realities
    • Munos BH, Chin WW,. A call for sharing: adapting pharmaceutical research to new realities. Sci Transl Med 2009; 1: 9cm8.
    • (2009) Sci Transl Med , vol.1
    • Munos, B.H.1    Chin, W.W.2
  • 83
    • 0032534659 scopus 로고    scopus 로고
    • Attitudes in clinical trials
    • Armitage P,. Attitudes in clinical trials. Stat Med 1998; 17: 2675-2683.
    • (1998) Stat Med , vol.17 , pp. 2675-2683
    • Armitage, P.1
  • 84
    • 67649661825 scopus 로고    scopus 로고
    • Making trials matter: Pragmatic and explanatory trials and the problem of applicability
    • Treweek S, Zwarenstein M,. Making trials matter: pragmatic and explanatory trials and the problem of applicability. Trials 2009; 10: 37.
    • (2009) Trials , vol.10 , pp. 37
    • Treweek, S.1    Zwarenstein, M.2
  • 85
    • 34848839198 scopus 로고    scopus 로고
    • Clinical trials: Bridging the gap between efficacy and effectiveness
    • Depp C, Lebowitz BD,. Clinical trials: bridging the gap between efficacy and effectiveness. Int Rev Psychiatry 2007; 19: 531-539.
    • (2007) Int Rev Psychiatry , vol.19 , pp. 531-539
    • Depp, C.1    Lebowitz, B.D.2
  • 86
    • 75949085017 scopus 로고    scopus 로고
    • 2009 FDA drug approvals
    • Hughes B,. 2009 FDA drug approvals. Nat Rev Drug Discov 2010; 9 (2): 89-92.
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.2 , pp. 89-92
    • Hughes, B.1
  • 88
    • 73449107200 scopus 로고    scopus 로고
    • The future of drug development: Advancing clinical trial design
    • Orloff J, Douglas F, Pinheiro J, et al. The future of drug development: advancing clinical trial design. Nat Rev Drug Discov 2009; 8: 949-957.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 949-957
    • Orloff, J.1    Douglas, F.2    Pinheiro, J.3
  • 89
    • 33646243834 scopus 로고    scopus 로고
    • Adaptive design in clinical research: Issues, opportunities, and recommendations
    • discussion 311-2
    • Chang M, Chow SC, Pong A,. Adaptive design in clinical research: issues, opportunities, and recommendations. J Biopharm Stat 2006; 16: 299-309; discussion 311-2.
    • (2006) J Biopharm Stat , vol.16 , pp. 299-309
    • Chang, M.1    Chow, S.C.2    Pong, A.3
  • 90
    • 44949171503 scopus 로고    scopus 로고
    • Adaptive design methods in clinical trials-a review
    • Chow SC, Chang M,. Adaptive design methods in clinical trials-a review. Orphanet J Rare Dis 2008; 3: 11.
    • (2008) Orphanet J Rare Dis , vol.3 , pp. 11
    • Chow, S.C.1    Chang, M.2
  • 91
    • 65449116424 scopus 로고    scopus 로고
    • Statistical methods in translational medicine
    • Chow SC, Tse SK, Lin M,. Statistical methods in translational medicine. J Formos Med Assoc 2008; 107: 61-73.
    • (2008) J Formos Med Assoc , vol.107 , pp. 61-73
    • Chow, S.C.1    Tse, S.K.2    Lin, M.3
  • 92
    • 34047213941 scopus 로고    scopus 로고
    • Customizing treatment to the patient: Adaptive treatment strategies
    • Murphy SA, Collins LM, Rush AJ,. Customizing treatment to the patient: adaptive treatment strategies. Drug Alcohol Depend 2007; 88: S1-S3.
    • (2007) Drug Alcohol Depend , vol.88
    • Murphy, S.A.1    Collins, L.M.2    Rush, A.J.3
  • 94
    • 77954531445 scopus 로고    scopus 로고
    • Research review: Attention bias modification (ABM): A novel treatment for anxiety disorders
    • Bar-Haim Y,. Research review: Attention bias modification (ABM): a novel treatment for anxiety disorders. J Child Psychol Psychiatry 2010; 51: 859-870.
    • (2010) J Child Psychol Psychiatry , vol.51 , pp. 859-870
    • Bar-Haim, Y.1
  • 97
    • 78349271102 scopus 로고    scopus 로고
    • Effectiveness of a Brain-Computer Interface Based Programme for the Treatment of ADHD: A Pilot Study
    • Lim CG, Lee TS, Guan C, et al. Effectiveness of a Brain-Computer Interface Based Programme for the Treatment of ADHD: A Pilot Study. Psychopharmacol Bull 2010; 43: 73-82.
    • (2010) Psychopharmacol Bull , vol.43 , pp. 73-82
    • Lim, C.G.1    Lee, T.S.2    Guan, C.3
  • 98
    • 77950629468 scopus 로고    scopus 로고
    • D-cycloserine for the augmentation of an attentional training intervention for trait anxiety
    • Behar E, McHugh RK, Peckham A, Otto MW,. D-cycloserine for the augmentation of an attentional training intervention for trait anxiety. J Anxiety Disord 2010; 24: 440-445.
    • (2010) J Anxiety Disord , vol.24 , pp. 440-445
    • Behar, E.1    McHugh, R.K.2    Peckham, A.3    Otto, M.W.4
  • 99
    • 62449184998 scopus 로고    scopus 로고
    • Roundtable on expanding capacity for comparative effectiveness research in the United States: Discussion took place on June 3, 2007, at the Academy Health Annual Research Meeting in Orlando, FL
    • Tunis S, Clancy C, Helms WD, McGinnis JM, Pearson SD,. Roundtable on expanding capacity for comparative effectiveness research in the United States: discussion took place on June 3, 2007, at the Academy Health Annual Research Meeting in Orlando, FL. Health Serv Res 2009; 44: 327-342.
    • (2009) Health Serv Res , vol.44 , pp. 327-342
    • Tunis, S.1    Clancy, C.2    Helms, W.D.3    McGinnis, J.M.4    Pearson, S.D.5
  • 101
    • 0141684982 scopus 로고    scopus 로고
    • Practical clinical trials: Increasing the value of clinical research for decision making in clinical and health policy
    • Tunis SR, Stryer DB, Clancy CM,. Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy. Jama 2003; 290: 1624-1632.
    • (2003) Jama , vol.290 , pp. 1624-1632
    • Tunis, S.R.1    Stryer, D.B.2    Clancy, C.M.3
  • 102
    • 65649121473 scopus 로고    scopus 로고
    • Does comparative-effectiveness research threaten personalized medicine?
    • Garber AM, Tunis SR,. Does comparative-effectiveness research threaten personalized medicine? N Engl J Med 2009; 360: 1925-1927.
    • (2009) N Engl J Med , vol.360 , pp. 1925-1927
    • Garber, A.M.1    Tunis, S.R.2
  • 103
    • 66749112971 scopus 로고    scopus 로고
    • Improving mental health treatments through comparative effectiveness research
    • Wang PS, Ulbricht CM, Schoenbaum M,. Improving mental health treatments through comparative effectiveness research. Health Aff (Millwood) 2009; 28: 783-791.
    • (2009) Health Aff (Millwood) , vol.28 , pp. 783-791
    • Wang, P.S.1    Ulbricht, C.M.2    Schoenbaum, M.3
  • 104
    • 12844279975 scopus 로고    scopus 로고
    • The promises and pitfalls of evidence-based medicine
    • Timmermans S, Mauck A,. The promises and pitfalls of evidence-based medicine. Health Aff (Millwood) 2005; 24: 18-28.
    • (2005) Health Aff (Millwood) , vol.24 , pp. 18-28
    • Timmermans, S.1    Mauck, A.2
  • 105
    • 0028395111 scopus 로고
    • Guidelines for clinical practice: Applications for primary care
    • Lohr KN,. Guidelines for clinical practice: applications for primary care. Int J Qual Health Care 1994; 6: 17-25.
    • (1994) Int J Qual Health Care , vol.6 , pp. 17-25
    • Lohr, K.N.1
  • 106
    • 0029261951 scopus 로고
    • Guidelines for clinical practice: What they are and why they count
    • Lohr KN,. Guidelines for clinical practice: what they are and why they count. J Law Med Ethics 1995; 23: 49-56.
    • (1995) J Law Med Ethics , vol.23 , pp. 49-56
    • Lohr, K.N.1
  • 107
    • 1242330428 scopus 로고    scopus 로고
    • Rating the strength of scientific evidence: Relevance for quality improvement programs
    • Lohr KN,. Rating the strength of scientific evidence: relevance for quality improvement programs. Int J Qual Health Care 2004; 16: 9-18.
    • (2004) Int J Qual Health Care , vol.16 , pp. 9-18
    • Lohr, K.N.1
  • 110
    • 9144261617 scopus 로고    scopus 로고
    • The Inventory of Depressive Symptomatology, Clinician Rating (IDS-C) and Self-Report (IDS-SR), and the Quick Inventory of Depressive Symptomatology, Clinician Rating (QIDS-C) and Self-Report (QIDS-SR) in public sector patients with mood disorders: A psychometric evaluation
    • Trivedi MH, Rush AJ, Ibrahim HM, et al. The Inventory of Depressive Symptomatology, Clinician Rating (IDS-C) and Self-Report (IDS-SR), and the Quick Inventory of Depressive Symptomatology, Clinician Rating (QIDS-C) and Self-Report (QIDS-SR) in public sector patients with mood disorders: a psychometric evaluation. Psychol Med 2004; 34: 73-82.
    • (2004) Psychol Med , vol.34 , pp. 73-82
    • Trivedi, M.H.1    Rush, A.J.2    Ibrahim, H.M.3
  • 111
    • 65249181526 scopus 로고    scopus 로고
    • Disruptive insights in psychiatry: Transforming a clinical discipline
    • Insel TR,. Disruptive insights in psychiatry: transforming a clinical discipline. J Clin Invest 2009; 119: 700-705.
    • (2009) J Clin Invest , vol.119 , pp. 700-705
    • Insel, T.R.1


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