Clinical messages from the treatment for adolescents with depression study (TADS)

American Journal of Psychiatry

Volumn 166, Issue 10, 2009, Pages 1118-1123

  March, John S ^a   Vitiello, Benedetto ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOXETINE;

CLINICAL PRACTICE; COGNITIVE THERAPY; COST EFFECTIVENESS ANALYSIS; DEPRESSION; DRUG EFFICACY; HEALTH CENTER; HUMAN; MAJOR DEPRESSION; PRIORITY JOURNAL; REVIEW; SUICIDAL BEHAVIOR; TREATMENT OUTCOME;

ADOLESCENT; ADOLESCENT BEHAVIOR; COGNITIVE THERAPY; COMBINED MODALITY THERAPY; DEPRESSIVE DISORDER, MAJOR; DOUBLE-BLIND METHOD; FEMALE; FLUOXETINE; GREAT BRITAIN; HARM REDUCTION; HUMANS; MALE; MULTICENTER STUDIES AS TOPIC; PLACEBOS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN; SEROTONIN UPTAKE INHIBITORS; SUICIDE; TREATMENT OUTCOME;

EID: 70349642663     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2009.08101606     Document Type: Review

References (44)

1. Angold A, Messer SC, Stangl D, Farmer EM, Costello EJ, Burns BJ: Perceived parental burden and service use for child and adolescent psychiatric disorders. Am J Public Health 1998; 88:75-80 (Pubitemid 28109645)
2. Gould MS, King R, Greenwald S, Fisher P, Schwab-Stone M, Kramer R, Flisher AJ, Goodman S, Canino G, Shaffer D: Psychopathology associated with suicidal ideation and attempts among children and adolescents. J Am Acad Child Adolesc Psychiatry 1998; 37:915-923 (Pubitemid 28406738)
3. Curry JF, Wells KC: Striving for effectiveness in the treatment of adolescent depression: cognitive behavior therapy for multisite community intervention. Cogn Behav Prac 2005; 12:177-185
4. Treatment for Adolescents with Depression Study Team: Treatment for Adolescents with Depression Study (TADS): rationale, design, and methods. J Am Acad Child Adolesc Psychiatry 2003; 42:531-542
5. March J, Silva S, Vitiello B; TADS Team: The Treatment for Adolescents with Depression Study (TADS): methods and message at 12 weeks. J Am Acad Child Adolesc Psychiatry 2006; 45:1393-1403 (Pubitemid 44900912)
6. Apter A, Kronenberg S, Brent D: Turning darkness into light: a new landmark study on the treatment of adolescent depression: comments on the TADS study. Eur Child Adolesc Psychiatry 2005; 14:113-116 (Pubitemid 44465292)
7. Brent DA: Glad for what TADS adds, but many TADS grads still sad. J Am Acad Child Adolesc Psychiatry 2006; 45:1461-1464
8. Jensen PS: NIMH's TADS: More than just a tad of progress? Cogn Behav Prac 2005; 12:156-158
9. Jensen PS: After TADS, can we measure up, catch up, and ante up? J Am Acad Child Adolesc Psychiatry 2006; 45:1456-1460
10. Treatment for Adolescents with Depression Study (TADS) Team: The Treatment for Adolescents with Depression Study (TADS): demographic and clinical characteristics. J Am Acad Child Adolesc Psychiatry 2005; 44:28-40
11. March J, Silva S, Petrycki S, Curry J, Wells K, Fairbank J, Burns B, Domino M, McNulty S, Vitiello B, Severe J; Treatment for Adolescents with Depression Study (TADS) Team: Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression: Treatment for Adolescents with Depression Study (TADS) randomized controlled trial. JAMA 2004; 292:807-820
12. March J, Silva S, Petrycki S, Curry J, Wells K, Fairbank J, Burns B, Domino M, McNulty S, Vitiello B, Severe J; Treatment for Adolescents with Depression Study (TADS) Team: The Treatment for Adolescents with Depression Study (TADS): long-term effectiveness and safety outcomes. Arch Gen Psychiatry 2007; 64:1132-1143
13. Treatment for Adolescents with Depression Study (TADS) Team: The Treatment for Adolescents with Depression Study (TADS): outcomes over one year of naturalistic follow-up. Am J Psychiatry (published online Sept 1, 2009; doi: 10.1176/appi.ajp.2009.08111620)
14. March JS, Szatmari P, Bukstein O, Chrisman A, Kondo D, Hamilton JD, Kremer CM, Kratochvil CJ: AACAP 2005 Research Forum: speeding the adoption of evidence-based practice in pediatric psychiatry. J Am Acad Child Adolesc Psychiatry 2007; 46:1098-1110
15. Kratochvil CJ, Vitiello B, Walkup J, Emslie G, Waslick BD, Weller EB, Burke WJ, March JS: Selective serotonin reuptake inhibitors in pediatric depression: Is the balance between benefits and risks favorable? J Child Adolesc Psychopharmacol 2006; 16:11-24
16. Birmaher B, Brent D, AACAP Work Group on Quality Issues, Bernet W, Bukstein O, Walter H, Benson RS, Chrisman A, Farchione T, Greenhill L, Hamilton J, Keable H, Kinlan J, Schoettle U, Stock S, Ptakowski KK, Medicus J: Practice parameter for the assessment and treatment of children and adolescents with depressive disorders. J Am Acad Child Adolesc Psychiatry 2007; 46:1503-1526
17. Kratochvil C, Emslie G, Silva S, McNulty S, Walkup J, Curry J, Reinecke M, Vitiello B, Rohde P, Feeny N, Casat C, Pathak S, Weller E, May D, Mayes T, Robins M, March J; TADS Team: Acute time to response in the Treatment for Adolescents with Depression Study. J Am Acad Child Adolesc Psychiatry 2006; 45:1412-1418 (Pubitemid 44900914)
18. Vitiello B, Rohde P, Silva S, Wells K, Casat C, Waslick B, Simons A, Reinecke M, Weller E, Kratochvil C, Walkup J, Pathak S, Robins M, March J; TADS Team: Functioning and quality of life in the Treatment for Adolescents with Depression Study (TADS). J Am Acad Child Adolesc Psychiatry 2006; 45:1419-1426 (Pubitemid 44900915)
19. Kennard B, Silva S, Vitiello B, Curry J, Kratochvil C, Simons A, Hughes J, Feeny N, Weller E, Sweeney M, Reinecke M, Pathak S, Ginsburg G, Emslie G, March J; TADS Team: Remission and residual symptoms after short-term treatment in the Treatment of Adolescents with Depression Study (TADS). J Am Acad Child Adolesc Psychiatry 2006; 45:1404-1411 (Pubitemid 44900913)
20. Emslie G, Kratochvil C, Vitiello B, Silva S, Mayes T, McNulty S, Weller E, Waslick B, Casat C, Walkup J, Pathak S, Rohde P, Posner K, March J; Columbia Suicidality Classification Group; TADS Team: Treatment for Adolescents with Depression Study (TADS): safety results. J Am Acad Child Adolesc Psychiatry 2006; 45:1440-1455
21. Fava M, Rush AJ, Trivedi MH, Nierenberg AA, Thase ME, Sackeim HA, Quitkin FM, Wisniewski S, Lavori PW, Rosenbaum JF, Kupfer DJ: Background and rationale for the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study. Psychiatr Clin North Am 2003; 26:457-494 (Pubitemid 36583573)
22. Kennard B, Silva S, Tonev ST, Rohde P, Hughes J, Vitiello B, Kratochvil C, Curry J, Emslie G, Reinecke M, March J: Remission and recovery in the Treatment of Adolescents with Depression Study (TADS): acute and long-term outcomes. J Am Acad Child Adolesc Psychiatry (Epub ahead of print, Jan 2, 2009)
23. Rohde P, Silva SG, Tonev ST, Kennard BD, Vitiello B, Kratochvil CJ, Reinecke MA, Curry JF, Simons AD, March JS: Achievement and maintenance of sustained response during the Treatment for Adolescents with Depression Study continuation and maintenance therapy. Arch Gen Psychiatry 2008; 65:447-455
24. Emslie GJ, Kennard BD, Mayes TL, Nightingale-Teresi J, Carmody T, Hughes CW, Rush AJ, Tao R, Rintelmann JW: Fluoxetine versus placebo in preventing relapse of major depression in children and adolescents. Am J Psychiatry 2008; 165:459-467 (Pubitemid 351694289)
25. Kennard BD, Silva SG, Mayes TL, Rohde P, Hughes JL, Vitiello B, Kratochvil CJ, Curry JF, Emslie GJ, Reinecke MA, March JS; TADS Team: Assessment of safety and long-term outcomes of initial treatment with placebo in TADS. Am J Psychiatry 2009; 166:337-344
26. Kovacs M, Feinberg TL, Crouse-Novak MA, Paulauskas SL, Finkelstein R: Depressive disorders in childhood, I: a longitudinal prospective study of characteristics and recovery. Arch Gen Psychiatry 1984; 41:229-237
27. Lewinsohn P, Clarke G, Seeley J, Rohde P: Major depression in community adolescents: age at onset, episode duration, and time to recurrence. J Am Acad Child Adolesc Psychiatry 1994; 33:809-818 (Pubitemid 24196904)
28. Birmaher B, Brent DA, Kolko D, Baugher M, Bridge J, Holder D, Iyengar S, Ulloa RE: Clinical outcome after short-term psychotherapy for adolescents with major depressive disorder. Arch Gen Psychiatry 2000; 57:29-36 (Pubitemid 30035656)
29. Emslie GJ, Rush AJ, Weinberg WA, Kowatch RA, Carmody T, Mayes TL: Fluoxetine in child and adolescent depression: acute and maintenance treatment. Depress Anxiety 1998; 7:32-39 (Pubitemid 28248517)
30. Emslie GJ: Improving outcome in pediatric depression. Am J Psychiatry 2008; 165:1-3
31. Hammad TA, Laughren T, Racoosin J: Suicidality in pediatric patients treated with antidepressant drugs. Arch Gen Psychiatry 2006; 63:332-339 (Pubitemid 43345358)
32. Bridge JA, Iyengar S, Salary CB, Barbe RP, Birmaher B, Pincus HA, Ren L, Brent DA: Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials. JAMA 2007; 297:1683-1696
33. Gibbons RD, Brown CH, Hur K, Marcus SM, Bhaumik DK, Erkens JA, Herings RM, Mann JJ: Early evidence on the effects of regulators' suicidality warnings on SSRI prescriptions and suicide in children and adolescents. Am J Psychiatry 2007; 164:1356-1363 (Pubitemid 47461135)
34. Domino ME, Burns BJ, Silva SG, Kratochvil CJ, Vitiello B, Reinecke MA, Mario J, March JS: Cost-effectiveness of treatments for adolescent depression: results from TADS. Am J Psychiatry 2008; 165:588-596 (Pubitemid 351705335)
35. Domino ME, Foster EM, Vitiello B, Kratochvil C, Burns BJ, Silva SG, Reinecke MA, March JS: Relative cost-effectiveness of treatments for adolescent depression: 36-week results from the TADS randomized trial. J Am Acad Child Adolesc Psychiatry 2009; 48: 711-720
36. Goodyer IM, Dubicka B, Wilkinson P, Kelvin R, Roberts C, Byford S, Breen S, Ford C, Barrett B, Leech A, Rothwell J, White L, Harrington R: A randomised controlled trial of cognitive behaviour therapy in adolescents with major depression treated by selective serotonin reuptake inhibitors: The ADAPT trial. Health Technol Assess 2008; 12:iii-iv, (Pubitemid 351954369)
37. Brent D, Emslie G, Clarke G, Wagner KD, Asarnow JR, Keller M, Vitiello B, Ritz L, Iyengar S, Abebe K, Birmaher B, Ryan N, Kennard B, Hughes C, DeBar L, McCracken J, Strober M, Suddath R, Spirito A, Leonard H, Melhem N, Porta G, Onorato M, Zelazny J: Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: the TORDIA randomized controlled trial. JAMA 2008; 299:901-913
38. Hughes CW, Emslie GJ, Crismon ML, Posner K, Birmaher B, Ryan N, Jensen P, Curry J, Vitiello B, Lopez M, Shon SP, Pliszka SR, Trivedi MH; Texas Consensus Conference Panel on Medication Treatment of Childhood Major Depressive Disorder: Texas Children's Medication Algorithm Project: update from Texas Consensus Conference Panel on Medication Treatment of Childhood Major Depressive Disorder. J Am Acad Child Adolesc Psychiatry 2007; 46:667-686
39. Cheung AH, Zuckerbrot RA, Jensen PS, Laraque D, Stein RE; GLAD-PC Steering Group. Guidelines for Adolescent Depression in Primary Care (GLAD-PC), II: treatment and ongoing management. Pediatrics 2007; 120:e1313-e1326 (Pubitemid 350085548)
40. National Institute for Health and Clinical Excellence: Depression in Children and Young People. London, NICE, 2004
41. Curry J, Rohde P, Simons A, Silva S, Vitiello B, Kratochvil C, Reinecke M, Feeny N, Wells K, Pathak S, Weller E, Rosenberg D, Kennard B, Robins M, Ginsburg G, March J; TADS Team: Predictors and moderators of acute outcome in the Treatment for Adolescents with Depression Study (TADS). J Am Acad Child Adolesc Psychiatry 2006; 45:1427-1439 (Pubitemid 44900916)
42. March JS: The future of psychotherapy for mentally ill children and adolescents. J Child Psychol Psychiatry 2009; 50:170-179
43. March J, Kratochvil C, Clarke G, Beardslee W, Derivan A, Emslie G, Green EP, Heiligenstein J, Hinshaw S, Hoagwood K, Jensen P, Lavori P, Leonard H, McNulty J, Michaels MA, Mossholder A, Osher T, Petti T, Prentice E, Vitiello B, Wells K: AACAP 2002 Research Forum: placebo and alternatives to placebo in randomized controlled trials in pediatric psychopharmacology. J Am Acad Child Adolesc Psychiatry 2004; 43:1046-1056
44. Vitiello B, Kratochvil CJ, Silva S, Curry J, Reinecke M, Pathak S, Waslick B, Hughes CW, Prentice ED, May DE, March JS: Research knowledge among the participants in the Treatment for Adolescents with Depression Study (TADS). J Am Acad Child Adolesc Psychiatry 2007; 46:1642-1650 (Pubitemid 350146529)