Plasma C-terminal pro-endothelin-1 is associated with left ventricular mass index and aortic root diameter in African-American adults with hypertension

Journal of Human Hypertension

Volumn 25, Issue 2, 2011, Pages 106-113

  Al Omari, M A ^a   Khaleghi, M ^a   Mosley Jr , T H ^b   Morgenthaler, N G ^c   Struck, J ^c   Bergmann, A ^c   Kullo, I J ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^c BRAHMS AG   (Germany)

Author keywords

African Americans; aortic root diameter; endothelin 1; left ventricular mass

Indexed keywords

CARBOXY TERMINAL PRO ENDOTHELIN 1; ENDOTHELIN 1 DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; AFRICAN AMERICAN; AORTA ROOT; ARTICLE; ASSAY; DISEASE MARKER; FEMALE; HEART LEFT VENTRICLE MASS; HUMAN; HYPERTENSION; IMMUNOLUMINOMETRIC ASSAY; MAJOR CLINICAL STUDY; MALE; PROTEIN BLOOD LEVEL; TARGET ORGAN;

AFRICAN AMERICANS; AGED; AORTIC VALVE; BIOLOGICAL MARKERS; CHEMILUMINESCENT MEASUREMENTS; CONFOUNDING FACTORS (EPIDEMIOLOGY); ECHOCARDIOGRAPHY, DOPPLER; ENDOTHELIN-1; FEMALE; HEART VENTRICLES; HUMANS; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; MALE; MIDDLE AGED; PEPTIDE FRAGMENTS; REGRESSION ANALYSIS; RISK FACTORS; UNITED STATES;

EID: 78651385741     PISSN: 09509240     EISSN: 14765527     Source Type: Journal    
DOI: 10.1038/jhh.2010.20     Document Type: Article

References (39)

1. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y et al. A novel potent vasocon-strictor peptide produced by vascular endothelial cells. Nature 1988; 332(6163): 411-415.
2. Agapitov AV, Haynes WG. Role of endothelin in cardiovascular disease. J Renin Angiotensin Aldoster-one Syst 2002; 3(1): 1-15.
3. Fujisaki H, Ito H, Hirata Y, Tanaka M, Hata M, Lin M et al. Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression. J Clin Invest 1995; 96(2): 1059-1065.
4. Yoshimoto S, Ishizaki Y, Sasaki T, Murota S. Effect of carbon dioxide and oxygen on endothelin production by cultured porcine cerebral endothelial cells. Stroke 1991; 22(3): 378-383.
5. Weitzberg E, Ahlborg G, Lundberg JM. Long-lasting vasoconstriction and efficient regional extraction of endothelin-1 in human splanchnic and renal tissues. Biochem Biophys Res Commun 1991; 180(3): 1298-1303.
6. Brunner F, Stessel H, Watzinger N, Loffler BM, Opie LH. Binding of endothelin to plasma proteins and tissue receptors: effects on endothelin determination vasoactivity, and tissue kinetics. FEBS Lett 1995; 373(1): 97-101.
7. Sirvio ML, Metsarinne K, Saijonmaa O, Fyhrquist F. Tissue distribution and half-life of 125I-endothelin in the rat: importance of pulmonary clearance. Biochem Biophys Res Commun 1990; 167(3): 1191-1195.
8. Papassotiriou J, Morgenthaler NG, Struck J, Alonso C, Bergmann A. Immunoluminometric assay for measurement of the C-terminal endothelin-1 pre-cursor fragment in human plasma. Clin Chem 2006; 52(6): 1144-1151.
9. Casale PN, Devereux RB, Milner M, Zullo G, Harshfield GA, Pickering TG et al. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med 1986; 105(2): 173-178.
10. Liao Y, Cooper RS, McGee DL, Mensah GA, Ghali JK. The relative effects of left ventricular hypertrophy, coronary artery disease, and ventricular dysfunction on survival among black adults. JAMA 1995; 273(20): 1592-1597.
11. Gardin JM, Arnold AM, Polak J, Jackson S, Smith V, Gottdiener J. Usefulness of aortic root dimension in persons >or=65 years of age in predicting heart failure, stroke, cardiovascular mortality, all-cause mortality and acute myocardial infarction (from the Cardiovascular Health Study). Am J Cardiol 2006; 97(2): 270-275.
12. Kizer JR, Arnett DK, Bella JN, Paranicas M, Rao DC, Province MA et al. Differences in left ventricular structure between black and white hypertensive adults: the Hypertension Genetic Epidemiology Net-work study. Hypertension 2004; 43(6): 1182-1188.
13. Kim CX, Bailey KR, Klee GG, Ellington AA, Liu G, Mosley TH et al. Sex and ethnic differences in 47 candidate proteomic markers of cardiovascular dis-ease: The Mayo Clinic Proteomic Markers of Arterio-sclerosis Study. PLoS One 2010; 5(2): e9065.
14. Boerwinkle E. Multi-center genetic study of hyperten-sion: the Family Blood Pressure Program (FBPP). Hypertension 2002; 39(1): 3-9.
15. Al-Omari MA, Khaleghi M, Mosley Jr TH, Turner ST, Morgenthaler NG, Struck J et al. Mid-regional pro-adrenomedullin is associated with pulse pressure, left ventricular mass, and albuminuria in African Amer-icans with hypertension. Am J Hypertens 2009; 22(8): 860-866.
16. Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S et al. Using standardized serum creati-nine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med 2006; 145(4): 247-254.
17. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to ne-cropsy findings. Am J Cardiol 1986; 57(6): 450-458.
18. Quinones MA, Waggoner AD, Reduto LA, Nelson JG, Young JB, Winters Jr WL et al. A new, simplified and accurate method for determining ejection fraction with two-dimensional echocardiography. Circulation 1981; 64(4): 744-753.
19. Roman MJ, Devereux RB, Kramer-Fox R, O'Loughlin J. Two-dimensional echocardiographic aortic root dimensions in normal children and adults. Am J Cardiol 1989; 64(8): 507-512.
20. Jernberg T, Stridsberg M, Lindahl B. Usefulness of plasma N-terminal proatrial natriuretic peptide (proANP) as an early predictor of outcome in unstable. Am J Cardiol 2002; 89(1): 64-66.
21. Mueller T, Gegenhuber A, Poelz W, Haltmayer M. Head-to-head comparison of the diagnostic utility of BNP and NT-proBNP in symptomatic and asympto-matic structural heart disease. Clin Chim Acta 2004; 341(1-2): 41-48.
22. Aubin P, Le Brun G, Moldovan F, Villette JM, Creminon C, Dumas J et al. Sandwich-type enzyme immunoassay for big endothelin-I in plasma: concen-trations in healthy human subjects unaffected by sex or posture. Clin Chem 1997; 43(1): 64-70.
23. Hua L, Li C, Xia D, Qu P, Li Z, Zhang W et al. Relationship between hypertensive left ventricular hypertrophy and levels of endothelin and nitric oxide. Hypertens Res 2000; 23(4): 377-380.
24. Parrinello G, Scaglione R, Pinto A, Corrao S, Cecala M, Di Silvestre G et al. Central obesity and hypertension: the role of plasma endothelin. Am J Hypertens 1996; 9(12 Part 1): 1186-1191.
25. Lowbeer C, Ottosson-Seeberger A, Gustafsson SA, Norrman R, Hulting J, Gutierrez A. Increased cardiac troponin T and endothelin-1 concentrations in dialysis patients may indicate heart disease. Nephrol Dial Transplant 1999; 14(8): 1948-1955.
26. Irzmanski R, Banach M, Piechota M, Kowalski J, Barylski M, Cierniewski C et al. Atrial and brain natriuretic peptide and endothelin-1 concentration in patients with idiopathic arterial hypertension: the dependence on the selected morphological para-meters. Clin Exp Hypertens 2007; 29(3): 149-164.
27. Olsen MH, Wachtell K, de Simone G, Palmieri V, Dige-Petersen H, Devereux RB et al. Is inappropriate left ventricular mass related to neurohormonal factors and/or arterial changes in hypertension? A LIFE substudy. J Hum Hypertens 2004; 18(6): 437-443.
28. Uusimaa P, Tokola H, Ylitalo A, Vuolteenaho O, Ruskoaho H, Risteli J et al. Plasma B-type natriuretic peptide reflects left ventricular hypertrophy and diastolic function in hypertension. Int J Cardiol 2004; 97(2): 251-256.
29. Sayama H, Nakamura Y, Saito N, Kinoshita M, Suda M. Relationship between left ventricular geometry and brain natriuretic peptide levels in elderly subjects. Gerontology 2000; 46(2): 71-77.
30. Masaki T, Kimura S, Yanagisawa M, Goto K. Molecular and cellular mechanism of endothelin regulation. Implications for vascular function. Circulation 1991; 84(4): 1457-1468.
31. Ichikawa KI, Hidai C, Okuda C, Kimata SI, Matsuoka R, Hosoda S et al. Endogenous endothelin-1 mediates cardiac hypertrophy and switching of myosin heavy chain gene expression in rat ventricular myocardium. J Am Coll Cardiol 1996; 27(5): 1286-1291.
32. Yorikane R, Sakai S, Miyauchi T, Sakurai T, Sugishita Y, Goto K. Increased production of endothelin-1 in the hypertrophied rat heart due to pressure overload. FEBS Lett 1993; 332(1-2): 31-34.
33. Ito H, Hirata Y, Hiroe M, Tsujino M, Adachi S, Takamoto T et al. Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes. Circ Res 1991; 69(1): 209-215.
34. Kaddoura S, Firth JD, Boheler KR, Sugden PH, Poole-Wilson PA. Endothelin-1 is involved in norepinephr-ine-induced ventricular hypertrophy in vivo. Acute effects of bosentan, an orally active, mixed endothelin ETA and ETB receptor antagonist. Circulation 1996; 93(11): 2068-2079.
35. Palmieri V, Bella JN, Arnett DK, Roman MJ, Oberman A, Kitzman DW et al. Aortic root dilatation at sinuses of valsalva and aortic regurgitation in hypertensive and normotensive subjects: The Hypertension Genetic Epidemiology Network Study. Hypertension 2001; 37(5): 1229-1235.
36. Cuspidi C, Meani S, Valerio C, Esposito A, Sala C, Maisaidi M et al. Ambulatory blood pressure, target organ damage and aortic root size in never-treated essential hypertensive patients. J Hum Hypertens 2007; 21(7): 531-538.
37. Vasan RS, Larson MG, Levy D. Determinants of echocardiographic aortic root size. The Framingham Heart Study. Circulation 1995; 91(3): 734-740.
38. Ergul A, Portik-Dobos V, Giulumian AD, Molero MM, Fuchs LC. Stress upregulates arterial matrix metallo-proteinase expression and activity via endothelin A receptor activation. Am J Physiol Heart Circ Physiol 2003; 285(5): H2225-H2232.
39. Murray DB, Gardner JD, Brower GL, Janicki JS. Endothelin-1 mediates cardiac mast cell degranula-tion, matrix metalloproteinase activation, and myocar-dial remodeling in rats. Am J Physiol Heart Circ Physiol 2004; 287(5): H2295-H2299.