The Y-chromosome landscape of the Philippines: Extensive heterogeneity and varying genetic affinities of Negrito and non-Negrito groups

European Journal of Human Genetics

Volumn 19, Issue 2, 2011, Pages 224-230

  Delfin, Frederick ^a,b   Salvador, Jazelyn M ^a   Calacal, Gayvelline C ^a   Perdigon, Henry B ^a   Tabbada, Kristina A ^a   Villamor, Lilian P ^a   Halos, Saturnina C ^a   Gunnarsdóttir, Ellen ^b   Myles, Sean ^a,f   Hughes, David A ^b   Xu, Shuhua ^c   Jin, Li ^c   Lao, Oscar ^d   Kayser, Manfred ^d   Hurles, Matthew E ^e   Stoneking, Mark ^b   De Ungria, Maria Corazon A ^a  

^a University of the Philippines Diliman   (Philippines)

^b MAX PLANCK INSTITUTE FOR EVOLUTIONARY ANTHROPOLOGY   (Germany)

^c MAX PLANCK INSTITUTE   (Germany)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^f Department of Obstetrics Gynecology   (United States)

Author keywords

Filipino; genetic affinity; heterogeneity; Negrito; Y chromosome

Indexed keywords

ARTICLE; ASIA; AUSTRALIA; GENETIC DRIFT; GENETIC HETEROGENEITY; GENETIC VARIABILITY; HUMAN; MALE; MIGRATION; NEGRITO; PHILIPPINES; POPULATION GENETICS; PRIORITY JOURNAL; RACE; Y CHROMOSOME;

AFRICAN CONTINENTAL ANCESTRY GROUP; ASIAN CONTINENTAL ANCESTRY GROUP; CHROMOSOMES, HUMAN, Y; EMIGRATION AND IMMIGRATION; ETHNIC GROUPS; GENETIC VARIATION; GENETICS, POPULATION; HAPLOTYPES; HUMANS; MALE; PHILIPPINES; POPULATION GROUPS; SOFTWARE;

EID: 78651382473     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2010.162     Document Type: Article

References (36)

1. O'Connell JF, Allen J: Dating the colonization of Sahul (Pleistocene Australia- New Guinea): a review of recent research. J Arch Sci 2004; 31: 835-853.
2. Dé troit F, Dizon E, Falguères C, Hameau S, Ronquillo W, Sémah F: Upper Pleistocene Homo sapiens from the Tabon cave (Palawan, The Philippines): description and dating of new discoveries. C R Palevol 2004; 3: 705-712.
3. Barker G, Barton H, Bird M et al: The 'human revolution' in lowland tropical Southeast Asia: the antiquity and behavior of anatomically modern humans at Niah Cave (Sarawak, Borneo). J Hum Evol 2007; 52: 243-261.
4. Gray RD, Drummond AJ, Greenhill SJ: Language Phylogenies Reveal Expansion Pulses and Pauses in Pacific Settlement. Science 2009; 323: 479-483.
5. Gordon Jr RG . (ed).: Ethnologue: Languages of the World, 15th edn. Dallas, Tex: SIL International. Online version: http://www.ethnologue.com/, 2005.
6. Scott WH: Prehispanic Source Materials For the Study of Philippine History. Quezon City, Philippines: New Day Publishers, 1984.
7. Jocano FL: Anthropology of the Filipino People I: Philippine Prehistory, Rediscovering Precolonial Heritage. Diliman, Quezon City, Philippines: PUNLAD Research House, Inc., 1998.
8. Bean RB: Types of Negritos in the Philippines. Am Anthro 1910; 12: 220-236.
9. Kashyap VK, Sitalaximi T, Sarkar BN, Trivedi R: Molecular relatedness of the aboriginal groups of Andaman and Nicobar Islands with similar ethnic populations. Int J Hum Genet 2003; 3: 5-11.
10. Reid LA: Unravelling the linguistic histories of Philippine Negritos; in Dutton T, Tyron DT (eds): Language Contact and Change in the Austronesian World. Berlin, Germany: Mouton de Gruyter, 1994, pp 443-475.
11. Tabbada KA, Trejaut J, Loo J-H et al: Philippine mitochondrial DNA diversity: A populated viaduct between Taiwan and Indonesia? Mol Biol Evol 2010; 27: 21-31.
12. Matsumoto H, Miyazaki T, Omoto K et al: Population Genetic Studies of the Philippine Negritos II Gm and Km Allotypes of Three Population Groups. Am J Hum Genet 1979; 31: 70-76.
13. Omoto K, Ueda S, Goriki K, Takahashi N, Misawa S, Pagaran IG: Population Genetic Studies of the Philippine Negritos. III. Identification of the Carbonic Anhydrase-1 Variant with CA1 Guam. Am J Hum Genet 1981; 33: 105-111.
14. The HUGO Pan-Asian SNP Consortium: Mapping Human Genetic Diversity in Asia. Science 2009; 326: 1541-1545.
15. Salvador JM, De Ungria MCA: Isolation of DNA from saliva of betel quid chewers using treated cards. J Forensic Sci 2003; 48: 794-797.
16. Paracchini S, Arredi B, Chalk R, Tyler-Smith C: Hierarchical high-throughput SNP genotyping of the human Y-chromosome using MALDI-TOF mass spectrometry. Nucleic Acids Res 2002; 30: e27 21-26.
17. Hurles ME, Sykes BC, Jobling MA, Forster P: The dual origin of the Malagasy in island Southeast Asia and East Africa: Evidence from maternal and paternal lineages. Am J Hum Genet 2005; 76: 894-901.
18. Hughes DA, Tang K, Strotmann R et al: Parallel Selection on TRPV6 in Human Populations. PLoS ONE 2008; 3: e1686 1681-1613.
19. Karafet TM, Mendez FL, Meilerman MB, Underhill PA, Zegura SL, Hammer MF: New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree. Genome Res 2008; 18: 830-838.
20. Kayser M, Brauer S, Weiss G, Schiefenhövel W, Underhill PA, Stoneking M: Independent Histories of Human Y Chromosomes from Melanesia and Australia. Am J Hum Genet 2001; 68: 173-190.
21. Kayser M, Brauer S, Weiss G et al: Reduced Y-chromosome, but not mitochondrial DNA, diversity in human populations from West New Guinea. Am J Hum Genet 2003; 72: 281-302.
22. Kayser M, Brauer S, Cordaux R et al: Melanesian and Asian Origins of Polynesians: mtDNA and Y Chromosome Gradients Across the Pacific. Mol Biol Evol 2006; 23: 2234-2244.
23. Kayser M, Choi Y, van Oven M et al: The Impact of the Austronesian Expansion: Evidence from mtDNA and Y Chromosome Diversity in the Admiralty Islands of Melanesia. Mol Biol Evol 2008; 25: 1362-1374.
24. Mona S, Grunz KE, Brauer S et al: Genetic Admixture History of Eastern Indonesia as Revealed by Y-Chromosome and Mitochondrial DNA Analysis. Mol Biol Evol 2009; 26: 1865-1877.
25. Excoffier L, Laval G, Schneider S: Arlequin ver. 3.0: An integrated software package for population genetics data analysis. Evol Bioinform Online 2005; 1: 47-50.
26. StatSoft, Inc: STATISTICA (data analysis software system), version 8.0, 2008, www.statsoft.com.
27. Wilson IJ, Weale ME, Balding DJ: Inferences from DNA data: population histories, evolutionary processes and forensic match probabilities. J R Stat Soc Ser A 2003; 166: 155-201.
28. Hey J, Nielsen R: Multilocus methods for estimating population sizes, migration rates and divergence time, with applications to the divergence of Drosophila pseudoobscura and D. perimilis. Genetics 2004; 167: 747-760.
29. Forster P, Kayser M, Meyer E et al: Phylogenetic Resolution of Complex Mutational Features at Y-STR DYS390 in Aboriginal Australians and Papuans. Mol Biol Evol 1998; 15: 1108-1114.
30. Lebar FM (ed.): Ethnic Groups of Insular Southeast Asia Volume 2: Philippines and Formosa. New Haven, USA: Human Relations Area Files Press, 1975.
31. Perry GH, Dominy NJ: Evolution of the human pygmy phenotype. Trends Ecol Evol 2009; 24: 220-225.
32. Karafet TM, Hallmark B, Cox MP et al: Major East-West Division Underlies Y Chromosome Stratification Across Indonesia MBE Advance Access published on March 5, 2010. doi:10.1093/molbev/msq063.
33. Kayser M, Brauer S, Weiss G et al: Melanesian origin of Polynesian Y chromosomes. Curr Biol 2000; 10: 1237-1246.
34. Chiaroni J, Underhill PA, Cavalli-Sforza LL: Y chromosome diversity, human expansion, drift, and cultural evolution. PNAS 2009; 106: 20174-20179.
35. Stoneking M, Delfin F: The Human Genetic History of East Asia: Weaving a Complex Tapestry. Curr Biol 2010; 20: R188-R193.
36. Pardoe C: Becoming Australian: evolutionary processes and biological variation from ancient to modern times. Before Farming [online version] 2006; 2006/1 article 4: 1-21