Retrotransposon-specific DNA hypomethylation and two-step loss-of-imprinting during WW45 haploinsufficiency-induced hepatocarcinogenesis

Biochemical and Biophysical Research Communications

Volumn 404, Issue 2, 2011, Pages 728-734

  Song, Ji Yun ^a   Lee, Joo Hyeon ^a   Joe, Cheol O ^a   Lim, Dae Sik ^a   Chung, Jae Hoon ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Activating histone modification; Cancer epigenetics; DNA methylation; H19 ICR; Liver cancer; Mouse models; Repressive histone modification; Retrotransposons; Tumorigenesis; WW45

Indexed keywords

HISTONE; SOMATOMEDIN B;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENE OVEREXPRESSION; HETEROCHROMATIN; HISTONE MODIFICATION; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETROPOSON; WILD TYPE;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; DNA METHYLATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC IMPRINTING; HAPLOINSUFFICIENCY; HISTONES; INSULIN-LIKE GROWTH FACTOR II; LIVER NEOPLASMS; MICE; MICE, MUTANT STRAINS; RETROELEMENTS;

MUS;

EID: 78651375982     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.12.052     Document Type: Article

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