A novel melanoma-targeting peptide screened by phage display exhibits antitumor activity

Journal of Molecular Medicine

Volumn 88, Issue 12, 2010, Pages 1255-1264

  Matsuo, Alisson L ^a   Tanaka, Aparecida S ^a   Juliano, Maria A ^a   Rodrigues, Elaine G ^a   Travassos, Luiz R ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antitumor activity; Bioactive peptide; Melanoma; Phage display

Indexed keywords

ANTINEOPLASTIC AGENT; CYSTEINYLSERYLSERYLARGINYLTHREONYLMETHIONYLHISTIDYLHISTIDYLCYSTEINE; MELAN A; PEPTIDE; UNCLASSIFIED DRUG;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER THERAPY; CELL ADHESION; CELL INVASION; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; DRUG INHIBITION; DRUG TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; PHAGE DISPLAY; TUMOR GROWTH; TUMOR VASCULARIZATION;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; CADHERINS; CELL ADHESION; CELL LINE, TUMOR; CELL LINEAGE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DRUG SCREENING ASSAYS, ANTITUMOR; MELANOMA; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; PEPTIDE LIBRARY; PEPTIDES, CYCLIC; PROTEIN BINDING; STAINING AND LABELING; SUBCUTANEOUS TISSUE; TUMOR STEM CELL ASSAY;

EID: 78651341420     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-010-0671-9     Document Type: Article

References (33)

1. Miller AJ, Mihm MC (2006) Mechanisms of disease-melanoma. N Engl J Med 355:51-65
2. Ruoslahti E (2002) Drug targeting to specific vascular sites. Drug Discov Today 7:1138-1143
3. St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW (2000) Genes expressed in human tumor endothelium. Science 289:1197-1202
4. Shadidi M, Sioud M (2002) Identification of novel carrier peptides for the specific delivery of therapeutics into cancer cells. Faseb J 16:256-258
5. Zhang BH, Zhang YQ, Wang JW, Zhang YD, Chen JJ, Pan YF, Ren LF, Hu ZY, Zhao JF, Liao MM, Wang SW (2007) Screening and identification of a targeting peptide to hepatocarcinoma from a phage display peptide library. Mol Med 13:246-254
6. Kolonin MG, Bover L, Sun J, Zurita AJ, Do KA, Lahdenranta J, Cardo-Vila M, Giordano RJ, Jaalouk DE, Ozawa MG, Moya CA, Souza GR, Staquicini FI, Kunyiasu A, Scudiero DA, Holbeck SL, Sausville EA, Arap W, Pasqualini R (2006) Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries. Cancer Res 66:34-40
7. Li ZH, Zhao RJ, Wu XH, Sun Y, Yao M, Li JJ, Xu YH, Gu JR (2005) Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics. Faseb J 19:1978-1985
8. Hu SJ, Guo XN, Xie HH, Du YL, Pan YL, Shi YQ, Wang J, Hong L, Han S, Zhang DT, Huang DW, Zhang KD, Bai FH, Jiang HP, Zhai HH, Nie YZ, Wu KC, Fan DM (2006) Phage display selection of peptides that inhibit metastasis ability of gastric cancer cells with high liver-metastatic potential. Biochem Biophys Res Commun 341:964-972
9. Pasqualini R, Arap W (2002) Translation of vascular diversity into targeted therapeutics. Ann Hematol 81: S66-S67
10. Zhang JB, Spring H, Schwab M (2001) Neuroblastoma tumor cell-binding peptides identified through random peptide phage display. Cancer Lett 171:153-164
11. Hong FD, Clayman GL (2000) Isolation of a peptide for targeted drug delivery into human head and neck solid tumors. Cancer Res 60:6551-6556
12. Kay BK, Kurakin AV, Hyde-DeRuyscher R (1998) From peptides to drugs via phage display. Drug Discov Today 3:370-378
13. Lee JH, Engler JA, Collawn JF, Moore BA (2001) Receptor mediated uptake of peptides that bind the human transferrin receptor. Eur J Biochem 268:2004-2012
14. Ladner RC, Sato AK, Gorzelany J, de Souza M (2004) Phage display-derived peptides as a therapeutic alternatives to antibodies. Drug Discov Today 9:525-529
15. Eriksson F, Culp WD, Massey R, Egevad L, Garland D, Persson MAA, Pisa P (2007) Tumor specific phage particles promote tumor regression in a mouse melanoma model. Cancer Immunol Immunother 56:677-687
16. Howell RC, Revskaya E, Pazo V, Nosanchuk JD, Casadevall A, Dadachova E (2007) Phage display library derived peptides that bind to human tumor melanin as potential vehicles for targeted radionuclide therapy of metastatic melanoma. Bioconjug Chem 18:1739-1748
17. Wu J, Wu MC, Zhang LF, Lei JY, Feng L, Jin J (2009) Identification of binding peptides of the ADAM15 disintegrin domain using phage display. J Biosci 34:213-220
18. Paschoalin T, Carmona AK, Rodrigues EG, Oliveira V, Monteiro HP, Juliano MA, Juliano L, Travassos LR (2007) Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth. Mol Cancer 6:44-58
19. Hirata IY, Cezari MHS, Nakaie C (1994) Internally quenched fluorogenic peptide substrates: solid phase, synthesis and fluorescence spectroscopy of peptides containing orthoaminobenzoil/dinitrophenyl groups as donor acceptor-pairs. Lett Peptide Sci 1:299-308
20. Dobroff AS, Rodrigues EG, Moraes JZ, Travassos LR (2002) Protective, anti-tumor monoclonal antibody recognizes a conformational epitope similar to melibiose at the surface of invasive murine melanoma cells. Hybrid Hybridomics 21:321-331
21. Pasqualini R, Ruoslahti E (1996) Organ targeting in vivo using phage display peptide libraries. Nature 380:364-366
22. Kennel SJ, Mirzadeh S, Hurst GB, Foote LJ, Lankford TK, Glowienka KA, Chappell LL, Kelso JR, Davern SM, Safavy A, Brechbiel MW (2000) Labeling and distribution of linear peptides identified using in vivo phage display selection for tumors. Nucl Med Biol 27:815-825
23. Oliveira V, Campos M, Hemerly JP, Ferro ES, Camargo ACM, Juliano MA, Juliano L (2001) Selective neurotensin-derived internally quenched fluorogenic substrates for neurolysin (EC 3.4.24.16): comparison with thimet oligopeptidase (EC 3.4.24.15) and neprilysin (EC 3.4.24.11). Anal Biochem 292:257-265
24. Guimaraes-Ferreira CA, Rodrigues EG, Mortaray RA, Cabralz H, Serrano FA, Ribeiro-dos-Santos R, Travassos LR (2007) Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa. Neoplasia 9:723-733
25. Franken NAP, Rodermond HM, Stap J, Haveman J, van Bree C (2006) Clonogenic assay of cells in vitro. Nat Protoc 1:2315-2319
26. Scott JK, Smith GP (1990) Searching for peptide ligands with an epitope library. Science 249:386-390
27. Sioud M, Forre O, Dybwad A (1996) Selection of ligands for polyclonal antibodies from random peptide libraries: potential identification of (auto) antigens that may trigger B and T cell responses in autoimmune diseases. Clin Immunol and Immunopathol 79:105-114
28. Kolonin M, Pasqualini R, Arap W (2001) Molecular addresses in blood vessels as targets for therapy. Curr Opin Chem Biol 5:308-313
29. Mummert ME, Mummert DI, Ellinger L, Takashima A (2003) Functional roles of hyaluronan in B16-F10 melanoma growth and experimental metastasis in mice. Mol Cancer Ther 2:295-300
30. Agiostratidou G, Li MM, Suyama K, Badano I, Keren R, Chung S, Anzovino A, Hulit J, Qian BZ, Bouzahzah B, Eugenin E, Loudig O, Phillips GR, Locker J, Hazan RB (2009) Loss of retinal cadherin facilitates mammary tumor progression and metastasis. Cancer Res 69:5030-5038
31. Takeichi M, Watabe M, Shibamoto S, Ito F, Oda H, Uemura T, Shimamura K (1993) Dynamic control of cell-cell adhesion for multicellular organization. C R Acad Sci Serie III 316:818-821
32. Liu LX, Lee NP, Chan VW, Xue W, Zender L, Zhang CS, Mao M, Dai HY, Wang XL, Xu MZ, Lee TK, Ng IO, Chen YC, Kung HF, Lowe SW, Poon RTP, Wang JH, Luk JM (2009) Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma. Hepatology 50:1453-1463
33. Zhou J, Li JM, Chen JZ, Liu YH, Gao WZ, Ding YQ (2009) Over-expression of CDH22 is associated with tumor progression in colorectal cancer. Tumor Biol 30:130-140