Effects of conjugated and unconjugated bile acids on the activity of the Vibrio cholerae porin OmpT

Molecular Membrane Biology

Volumn 28, Issue 1, 2011, Pages 69-78

  Pagel, Melissa ^a   Delcour, Anne H ^a  

^a University of Houston   (United States)

Author keywords

deoxycholic acid; electrophysiology; Outer membrane

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; GLYCODEOXYCHOLIC ACID; LITHOCHOLIC ACID; TAURODEOXYCHOLIC ACID; TOLC PROTEIN;

ARTICLE; CONJUGATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; IC 50; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; VIBRIO CHOLERAE;

BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BILE ACIDS AND SALTS; BINDING SITES; MODELS, MOLECULAR; PATCH-CLAMP TECHNIQUES; PORINS; VIBRIO CHOLERAE;

BACTERIA (MICROORGANISMS); VIBRIO CHOLERAE;

EID: 78651331824     PISSN: 09687688     EISSN: 14645203     Source Type: Journal    
DOI: 10.3109/09687688.2010.519727     Document Type: Article

References (41)

1. Baslé A, Iyer R, Delcour AH. 2004. Subconductance states in OmpF gating. Biochim Biophys Acta 1664:100-107.
2. Begley M, Gahan CG, Hill C. 2005. The interaction between bacteria and bile. FEMS Microbiol Rev 29:625-651.
3. Bina JE, Mekalanos JJ. 2001. Vibrio cholerae tolC is required for bile resistance and colonization. Infect Immun 69:4681-4685.
4. Bina JE, Provenzano D, Wang C, Bina XR, Mekalanos JJ. 2006. Characterization of the Vibrio cholerae vexAB and vexCD efflux systems. Arch Microbiol 186:171-181.
5. Butler SM, Camilli A. 2005. Going against the grain: Chemo-taxis and infection in Vibrio cholerae. Nat Rev Microbiol 3: 611-620.
6. Carey MC. 1984. Bile acids and bile salts: Ionization and solubility properties. Hepatology 4:66S-71S.
7. Carey MC, Duane WC. 1994. Enterohepatic circulation. In: Arias IM, Boyer JL, Fausto N, Jakoby WB, Schachter DA, Shafritz DA, editors. The liver: Biology and pathobiology. 3d ed. New York: Raven Press Ltd. pp 719-767.
8. Cerda-Maira FA, Ringelberg CS, Taylor RK. 2008. The bile response repressor BreR regulates expression of the Vibrio cholerae breAB efflux system operon. J Bacteriol 190: 7441-7452.
9. Chakrabarti SR, Chaudhuri K, Sen K, Das J. 1996. Porins of Vibrio cholerae: Purification and characterization of OmpU. J Bacteriol 178:524-530.
10. Chatterjee A, Chaudhuri S, Saha G, Gupta S, Chowdhury R. 2004. Effect of bile on the cell surface permeability barrier and efflux system of Vibrio cholerae. J Bacteriol 186:6809-6814.
11. Danelon C, Nestorovich EM, Winterhalter M, Ceccarelli M, Bezrukov SM. 2006. Interaction of zwitterionic penicillins with the OmpF channel facilitates their translocation. Biophys J 90:1617-1627.
12. Delcour AH, Martinac B, Adler J, Kung C. 1989. Modified reconstitution method used in patch-clamp studies of Escher-ichia coli ion channels. Biophys J 56:631-636.
13. Duret G, Delcour AH. 2006. Deoxycholic acid blocks Vibrio cholerae OmpT but not OmpU porin. J Biol Chem 281:19899-19905.
14. Duret G, Delcour AH. 2010. Size and dynamics of the Vibrio cholerae porins OmpU and OmpT probed by polymer exclusion. Biophys J 98:1820-1829.
15. Duret G, Simonet V, Delcour AH. 2007. Modulation of Vibrio cholerae porin function by acidic pH. Channels 1:70-79.
16. Gupta S, Chowdhury R. 1997. Bile affects production of virulence factors and motility of Vibrio cholerae. Infect Immun 65:1131-1134.
17. Hille B. 1992. Ionic channels of excitable membranes. Sunderland, MA: Sinauer Associates.
18. Hofmann AF. 1994. Bile acids. In: Arias IM, Boyer JL, Fausto N, Jakoby WB, Schachter DA, Shafritz DA, editors. The liver: Biology and pathobiology. 3rd ed. New York: Raven Press Ltd. pp 677-718.
19. Hofmann AF, Hagey LR. 2008. Bile acids: Chemistry, pathochem-istry, biology, pathobiology, and therapeutics. Cell Mol Life Sci 65:2461-2483.
20. Hofmann AF, Roda A. 1984. Physicochemical properties of bile acids and their relationship to biological properties: An overview of the problem. J Lipid Res 25:1477-1489.
21. Hung DT, Mekalanos JJ. 2005. Bile acids induce cholera toxin expression in Vibrio cholerae in a ToxT-independent manner. Proc Natl Acad Sci USA 102:3028-3033.
22. Hung DT, Zhu J, Sturtevant D, Mekalanos JJ. 2006. Bile acids stimulate biofilm formation in Vibrio cholerae. Mol Microbiol 59:193-201.
23. Kullman L, Winterhalter M, Bezrukov SM. 2002. Transport of maltodextrins through maltoporin: A single-channel study. Biophys J 82:803-812. (Pubitemid 34111221)
24. Lee SH, Hava DL, Waldor MK, Camilli A. 1999. Regulation and temporal expression patterns of Vibrio cholerae virulence genes during infection. Cell 99:625-634.
25. Nestorovich EM, Danelon C, Winterhalter M,Bezrukov SM. 2002. Designed to penetrate: Time-resolved interaction of single antibiotic molecules with bacterial pores. Proc Natl Acad Sci USA 99:9789-9794.
26. Nikaido H. 1996. Outer membrane. In: Neidhart FC, editor. Escherichia coli and Salmonella. Cellular and molecular biology. Washington, DC: ASM Press. pp 29-47.
27. Nikaido H. 2003. Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev 67:593-656.
28. Noh DO, Gilliland SE. 1993. Influence of bile on cellular integrity and beta-galactosidase activity of Lactobacillus acidophilus. J Dairy Sci 76:1253-1259.
29. Northfield TC, McColl I. 1973. Postprandial concentrations of free and conjugated bile acids down the length of the normal human small intestine. Gut 14:513-518.
30. Oelberg DG, Chari MV, Little JM, Adcock EW, Lester R. 1984. Lithocholate glucuronide is a cholestatic agent. J Clin Invest 73:1507-1514.
31. Pagel M, Simonet V, Li J, Lallemand M, Lauman B, Delcour AH. 2007. Phenotypic characterization of pore mutants of the Vibrio cholerae porin OmpU. J Bacteriol 189:8593-8600.
32. Provenzano D, Klose KE. 2000. Altered expression of the ToxR-regulated porins OmpU and OmpT diminishes Vibrio cholerae bile resistance, virulence factor expression, and intestinal colonization. Proc Natl Acad Sci USA 97:10220-10224.
33. Provenzano D, Lauriano CM, Klose KE. 2001. Characterization of the role of the ToxR-modulated outer membrane porins OmpU and OmpT in Vibrio cholerae virulence. J Bacteriol 183:3652-3662.
34. Provenzano D, Schuhmacher DA, Barker JL, Klose KE. 2000. The virulence regulatory protein ToxR mediates enhanced bile resistance in Vibrio cholerae and other pathogenic Vibrio species. Infect Immun 68:1491-1497.
35. Reidl J, Klose KE. 2002. Vibrio cholerae and cholera: Out of the water and into the host. FEMS Microbiol Rev 26:125-139.
36. Ridlon JM, Kang DJ, Hylemon PB. 2006. Bile salt biotransforma-tions by human intestinal bacteria. J Lipid Res 47:241-259.
37. Roda A, Hofmann AF, Mysels KJ. 1983. The influence of bile salt structure on self-association in aqueous solutions. J Biol Chem 258:6362-6370.
38. Schuhmacher DA, Klose KE. 1999. Environmental signals modulate ToxT-dependent virulence factor expression in Vibrio cholerae. J Bacteriol 181:1508-1514.
39. Simonet VC, Basle A, Klose KE, Delcour AH. 2003. The Vibrio cholerae porins OmpU and OmpT have distinct channel properties. J Biol Chem 278:17539-17545.
40. Vyvoda OS, Coleman R, Holdsworth G. 1977. Effects of different bile salts upon the composition and morphology of a liver plasma membrane preparation. Deoxycholate is more membrane damaging than cholate and its conjugates. Biochim Bio-phys Acta 465:68-76.
41. Wilson M. 2005. Microbial inhabitants of humans. Their ecology and role in health and disease. Cambridge, UK: Cambridge University Press.