Crucial epitopes of Wuchereria bancrofti abundant larval transcript recognized in natural infection

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 29, Issue 12, 2010, Pages 1481-1486

  Madhumathi, J ^a   Pradiba, D ^a   Prince, P R ^a   Jeyaprita, P J ^a   Rao, D N ^b   Kaliraj, P ^a  

^a ANNA UNIVERSITY   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ABUNDANT LARVAL TRANSCRIPT PROTEIN 2; EPITOPE; IMMUNOGLOBULIN G4; SECRETORY PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMORAL IMMUNITY; IMMUNOMODULATION; IMMUNOREACTIVITY; LYMPHATIC FILARIASIS; MICROFILARIA (NEMATODE LARVA); MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WUCHERERIA BANCROFTI;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; ELEPHANTIASIS, FILARIAL; EPITOPES; HELMINTH PROTEINS; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN ISOTYPES; LARVA; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; WUCHERERIA BANCROFTI;

EID: 78651308496     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-010-1026-8     Document Type: Article

References (20)

1. World Health Organization (WHO) (2006) Weekly epidemiological record, no. 22
2. RA Lawrence 2001 Immunity to filarial nematodes Vet Parasitol 100 33 44 1:CAS:528:DC%2BD3MXmtV2nt7g%3D 10.1016/S0304-4017(01)00481-2 11522404 (Pubitemid 32778426)
3. A Hoerauf J Satoguina M Saeftel S Specht 2005 Immunomodulation by filarial nematodes Parasite Immunol 27 417 429 1:CAS:528:DC%2BD2MXhtFOqtbzI 10.1111/j.1365-3024.2005.00792.x 16179035 (Pubitemid 41413489)
4. N Gomez-Escobar WF Gregory C Britton L Murray C Corton N Hall J Daub ML Blaxter RM Maizels 2002 Abundant larval transcript-1 and -2 genes from Brugia malayi: diversity of genomic environments but conservation of 5′ promoter sequences functional in Caenorhabditis elegans Mol Biochem Parasitol 125 59 71 1:CAS:528:DC%2BD38XptFKisb4%3D 10.1016/S0166-6851(02)00219-0 12467974
5. M Gnanasekar KV Rao YX He PK Mishra TB Nutman P Kaliraj K Ramaswamy 2004 Novel phage display-based subtractive screening to identify vaccine candidates of Brugia malayi Infect Immun 72 8 4707 4715 1:CAS:528:DC%2BD2cXmtlymsLo%3D 10.1128/IAI.72.8.4707-4715.2004 15271932 (Pubitemid 38989331)
6. S Ramachandran MP Kumar RM Rami HB Chinnaiah T Nutman P Kaliraj J McCarthy 2004 The larval specific lymphatic filarial ALT-2: induction of protection using protein or DNA vaccination Microbiol Immunol 48 945 955 1:CAS:528:DC%2BD2MXhtlarsbY%3D 15611611
7. JE Allen J Daub D Guiliano A McDonnell M Lizotte-Waniewski DW Taylor M Blaxter 2000 Analysis of genes expressed at the infective larval stage validates utility of Litomosoides sigmodontis as a murine model for filarial vaccine development Infect Immun 68 5454 5458 1:CAS:528:DC%2BD3cXmtVektLY%3D 10.1128/IAI.68.9.5454-5458.2000 10948183
8. JP Hewitson JR Grainger RM Maizels 2009 Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity Mol Biochem Parasitol 167 1 1 11 1:CAS:528:DC%2BD1MXntVGrs74%3D 10.1016/j.molbiopara.2009. 04.008 19406170
9. Saha S, Raghava GPS (2004) BcePred: prediction of continuous B-cell epitopes in antigenic sequences using physico-chemical properties. In: Nicosia G, Cutello V, Bentley PJ, Timis J (eds) ICARIS 2004, LNCS 3239, pp 197-204
10. B Peters J Sidney P Bourne HH Bui S Buus G Doh W Fleri M Kronenberg R Kubo O Lund D Nemazee JV Ponomarenko M Sathiamurthy SP Schoenberger S Stewart P Surko S Way S Wilson A Sette 2005 The design and implementation of the immune epitope database and analysis resource Immunogenetics 57 5 326 336 1:CAS:528:DC%2BD2MXltlagsbc%3D 10.1007/s00251-005-0803-5 15895191 (Pubitemid 40905051)
11. DA Hager RR Burgess 1980 Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes Anal Biochem 109 1 76 86 1:CAS:528:DyaL3MXktlGitQ%3D%3D 10.1016/0003-2697(80)90013-5 6258458 (Pubitemid 11140095)
12. PJ Hotez 2009 Mass drug administration and integrated control for the world's high-prevalence neglected tropical diseases Clin Pharmacol Ther 85 6 659 664 1:CAS:528:DC%2BD1MXmtVOgurs%3D 10.1038/clpt.2009.16 19322166
13. Y Wu G Egerton DJC Pappin RA Harrison MC Wilkinson A Underwood AE Bianco 2004 The secreted larval acidic proteins (SLAPs) of Onchocerca spp. are encoded by orthologues of the alt gene family of Brugia malayi and have host protective potential Mol Biochem Parasitol 134 213 224 1:CAS:528:DC%2BD2cXhvFanur8%3D 10.1016/j.molbiopara.2003.12.002 15003841 (Pubitemid 38304949)
14. WF Gregory AK Atmadja JE Allen RM Maizels 2000 The abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasis Infect Immun 68 4174 4179 1:CAS:528: DC%2BD3cXktlyntLg%3D 10.1128/IAI.68.7.4174-4179.2000 10858234 (Pubitemid 30434572)
15. S Thirugnanam P Pandiaraja K Ramaswamy V Murugan M Gnanasekar K Nandakumar MV Reddy P Kaliraj 2007 Brugia malayi: comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird model Exp Parasitol 116 4 483 491 1:CAS:528:DC%2BD2sXmtlWitrc%3D 10.1016/j.exppara.2007.02.017 17442307 (Pubitemid 46863429)
16. MH Van Regenmortel 2006 Immunoinformatics may lead to a reappraisal of the nature of B cell epitopes and of the feasibility of synthetic peptide vaccines J Mol Recognit 19 183 187 10.1002/jmr.768 16680720 (Pubitemid 43874852)
17. A Kurniawan M Yazdanbakhsh R van Ree R Aalberse ME Selkirk F Partono RM Maizels 1993 Differential expression of IgE and IgG4 specific antibody responses in asymptomatic and chronic human filariasis J Immunol 150 3941 3950 1:CAS:528:DyaK3sXkt1Kmt7w%3D 8473742
18. S Mahanty M Ravichandran U Raman K Jayaraman V Kumaraswami TB Nutman 1997 Regulation of parasite antigen-driven immune responses by interleukin-10 (IL-10) and IL-12 in lymphatic filariasis Infect Immun 65 5 1742 1747 1:CAS:528:DyaK2sXjtVKqtb4%3D 9125556
19. M Ravichandran S Mahanty V Kumaraswami TB Nutman K Jayaraman 1997 Elevated IL-10 mRNA expression and downregulation of Th1-type cytokines in microfilaraemic individuals with Wuchereria bancrofti infection Parasite Immunol 19 69 77 1:STN:280:DyaK2s3jtFChtA%3D%3D 10.1046/j.1365-3024.1997.d01-185.x 9076809
20. C Witt EA Ottesen 2001 Lymphatic filariasis: an infection of childhood Trop Med Int Health 6 8 582 606 1:STN:280:DC%2BD3Mrgs1Gntg%3D%3D 10.1046/j.1365-3156.2001.00765.x 11555425 (Pubitemid 32830479)