A single-use purification process for the production of a monoclonal antibody produced in a PER.C6 human cell line

Biotechnology Journal

Volumn 6, Issue 1, 2011, Pages 56-65

  Kuczewski, Michael ^a   Schirmer, Emily ^a   Lain, Blanca ^a   Zarbis Papastoitsis, Gregory ^b  

^a Percivia LLC   (United States)

^b Eleven Biotherapeutics   (United States)

Author keywords

Downstream processing; Membrane chromatography; Precipitation; Protein purification; Single use technology

Indexed keywords

DOWNSTREAM-PROCESSING; MEMBRANE CHROMATOGRAPHY; PRECIPITATION; PROTEIN PURIFICATION; SINGLE-USE TECHNOLOGY;

ANIMAL CELL CULTURE; BATCH CELL CULTURE; BATCH DATA PROCESSING; BIOREACTORS; CHROMATOGRAPHY; CLARIFICATION; MANUFACTURE; MONOCLONAL ANTIBODIES; PURIFICATION; TECHNOLOGY;

CELL CULTURE;

IMMUNOGLOBULIN G1 ANTIBODY; MONOCLONAL ANTIBODY;

ANION EXCHANGE; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CELL CULTURE; CELL SEPARATION; DOWNSTREAM PROCESSING; HYDROPHOBIC INTERACTION CHROMATOGRAPHY; PERFORMANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ANTIBODIES, MONOCLONAL; BIOTECHNOLOGY; CELL LINE; CHROMATOGRAPHY; HUMANS;

EID: 78651288673     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201000292     Document Type: Article

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