SP-8203 reduces oxidative stress via SOD activity and behavioral deficit in cerebral ischemia

Pharmacology Biochemistry and Behavior

Volumn 98, Issue 1, 2011, Pages 150-154

  Noh, Su Jin ^a   Lee, Sang Hyung ^b   Shin, Ki Young ^a   Lee, Chul Kyu ^c   Cho, Il Hwan ^c   Kim, Hye Sun ^a   Suh, Yoo Hun ^a  

^a Seoul National University   (South Korea)

^b Seoul National University Boramae Hospital   (South Korea)

^c Shinpoong Pharmaceutical Co   (South Korea)

Author keywords

Antioxidant; Cerebral ischemia; Earth worms; Neurology; NMDA antagonist; ROS

Indexed keywords

4 HYDROXYNONENAL; ANTIOXIDANT; CATALASE; DIZOCILPINE; GLUTAMIC ACID; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; MALONALDEHYDE; N [3 (2,4 DIOXO 1,4 DIHYDRO 2H QUINAZOLIN 3 YL)PROPYL] N [4 [3 (2,4 DIOXO 1,4 DIHYDRO 2H QUINAZOLIN 3 YL)PROPYLAMINO]BUTYL]ACETAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; SP 8203; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BEHAVIOR DISORDER; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN PROTECTION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; LATENT PERIOD; LIPID PEROXIDATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR PERFORMANCE; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ROTAROD TEST; STROKE;

ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BRAIN ISCHEMIA; CELL DEATH; CELL LINE; DISEASE MODELS, ANIMAL; DIZOCILPINE MALEATE; GLUTAMIC ACID; HUMANS; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MALE; MOTOR ACTIVITY; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; QUINAZOLINONES; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 78651284551     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2010.12.014     Document Type: Article

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