-
1
-
-
0041408235
-
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
-
McMurray JJ, Ostergren J., Swedberg K., et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet. 2003 ; 362 (9386). 767-771.
-
(2003)
Lancet
, vol.362
, Issue.9386
, pp. 767-771
-
-
McMurray, J.J.1
Ostergren, J.2
Swedberg, K.3
-
2
-
-
0041909380
-
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: The CHARM-Alternative trial
-
Granger CB, McMurray JJ, Yusuf S., et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial. Lancet. 2003 ; 362 (9386). 772-776.
-
(2003)
Lancet
, vol.362
, Issue.9386
, pp. 772-776
-
-
Granger, C.B.1
McMurray, J.J.2
Yusuf, S.3
-
3
-
-
3142776467
-
Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol or Metoprolol European Trial (COMET): Randomised controlled trial
-
Poole-Wilson PA, Swedberg K., Cleland JG, et al. Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial. Lancet. 2003 ; 362 (9377). 7-13.
-
(2003)
Lancet
, vol.362
, Issue.9377
, pp. 7-13
-
-
Poole-Wilson, P.A.1
Swedberg, K.2
Cleland, J.G.3
-
4
-
-
0023223146
-
Heart rate and cardiovascular mortality: The Framingham Study
-
Kannel WB, Kannel C., Paffenbarger Rsjr, Cupples LA Heart rate and cardiovascular mortality: the Framingham Study. Am Heart J. 1987 ; 113 (6). 1489-1494.
-
(1987)
Am Heart J.
, vol.113
, Issue.6
, pp. 1489-1494
-
-
Kannel, W.B.1
Kannel, C.2
Rsjr, P.3
Cupples, L.A.4
-
5
-
-
34548032376
-
Resting heart rate in cardiovascular disease
-
Fox K., Borer JS, Camm AJ, et al. Resting heart rate in cardiovascular disease. J Am Coll Cardiol. 2007 ; 50 (9). 823-830.
-
(2007)
J Am Coll Cardiol
, vol.50
, Issue.9
, pp. 823-830
-
-
Fox, K.1
Borer, J.S.2
Camm, A.J.3
-
6
-
-
35148892823
-
European guidelines on cardiovascular disease prevention in clinical practice: Executive summary
-
Graham I., Atar D., Borch-Johnsen K., et al. European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Eur Heart J. 2007 ; 28: 2375-2414.
-
(2007)
Eur Heart J
, vol.28
, pp. 2375-2414
-
-
Graham, I.1
Atar, D.2
Borch-Johnsen, K.3
-
7
-
-
12344330346
-
Elevated heart rate: A major risk factor for cardiovascular disease
-
Palatini P., Julius S. Elevated heart rate: a major risk factor for cardiovascular disease. Clin Exp Hypertens. 2004 ; 26 (7-8). 637-644.
-
(2004)
Clin Exp Hypertens
, vol.26
, Issue.7-8
, pp. 637-644
-
-
Palatini, P.1
Julius, S.2
-
8
-
-
28944438521
-
Predictor of mortality and morbidity in patients with chronic heart failure
-
Pocock SJ, Wang D., Pfeffer MA, et al. Predictor of mortality and morbidity in patients with chronic heart failure. Eur Heart J. 2006 ; 27 (1). 65-75.
-
(2006)
Eur Heart J
, vol.27
, Issue.1
, pp. 65-75
-
-
Pocock, S.J.1
Wang, D.2
Pfeffer, M.A.3
-
9
-
-
50649089781
-
Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): A subgroup analysis of a randomised controlled trial
-
Fox K., Ford I., Steg PG, Tendera M., Robertson M., Ferrari R. Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial. Lancet. 2008 ; 372 (9641). 817-821.
-
(2008)
Lancet
, vol.372
, Issue.9641
, pp. 817-821
-
-
Fox, K.1
Ford, I.2
Steg, P.G.3
Tendera, M.4
Robertson, M.5
Ferrari, R.6
-
10
-
-
0035853053
-
Heart rate and cardiac rhythm relationships with bisoprolol benefit in chronic heart failure in CIBIS II Trial
-
Lechat P., Hulot JS, Escolano S., et al. Heart rate and cardiac rhythm relationships with bisoprolol benefit in chronic heart failure in CIBIS II Trial. Circulation. 2001 ; 103 (10). 1428-1433.
-
(2001)
Circulation
, vol.103
, Issue.10
, pp. 1428-1433
-
-
Lechat, P.1
Hulot, J.S.2
Escolano, S.3
-
11
-
-
0141917494
-
I (f) inhibition: A novel mechanism of action
-
Di Francesco D. I (f) inhibition: a novel mechanism of action. Eur Heart J. 2003 ; 5 (suppl G). G19 - G25.
-
(2003)
Eur Heart J.
, vol.5
, Issue.SUPPL. G
-
-
Di Francesco, D.1
-
12
-
-
4544344025
-
Heart rate lowering by specific and selective I(f) current inhibition with ivabradine: A new therapeutic perspective in cardiovascular disease
-
Di Francesco D., Camm JA Heart rate lowering by specific and selective I(f) current inhibition with ivabradine: a new therapeutic perspective in cardiovascular disease. Drugs. 2004 ; 64 (16). 1757-1765.
-
(2004)
Drugs
, vol.64
, Issue.16
, pp. 1757-1765
-
-
Di Francesco, D.1
Camm, J.A.2
-
13
-
-
11144356194
-
Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function ad intrinsic myocardial structure in congestive heart failure
-
Mulder P., Barbier S., Chagraoui A., et al. Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function ad intrinsic myocardial structure in congestive heart failure. Circulation. 2004 ; 109 (13). 1674-1679.
-
(2004)
Circulation
, vol.109
, Issue.13
, pp. 1674-1679
-
-
Mulder, P.1
Barbier, S.2
Chagraoui, A.3
-
14
-
-
0022542458
-
A new method for detecting anaerobic threshold by gas exchange
-
Beaver WL, Wasserman K., Whipp BJ A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol. 1986 ; 60 (6). 2020-2027.
-
(1986)
J Appl Physiol
, vol.60
, Issue.6
, pp. 2020-2027
-
-
Beaver, W.L.1
Wasserman, K.2
Whipp, B.J.3
-
15
-
-
0024723470
-
Recommendations for quantitation of left ventricle by two-dimensional echocardiography: American Society of Echocardiography Committee on Standards and Subcommittee on Quantitation of Two-Dimensional Echocardiograms
-
Schiller NB, Shah PM, Crawford M., et al. Recommendations for quantitation of left ventricle by two-dimensional echocardiography: American Society of Echocardiography Committee on Standards and Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr. 1989 ; 2 (5). 358-367.
-
(1989)
J Am Soc Echocardiogr
, vol.2
, Issue.5
, pp. 358-367
-
-
Schiller, N.B.1
Shah, P.M.2
Crawford, M.3
-
16
-
-
0026699989
-
Assessment of patient outcome with the Minnesota Living with Heart Failure questionnaire: Reliability and validity during a randomized, double-bind, placebo-controlled trial of pimobendan
-
the Pimobendan Multicenter Research Group
-
Rector TS, Cohn JN with the Pimobendan Multicenter Research Group. Assessment of patient outcome with the Minnesota Living with Heart Failure questionnaire: reliability and validity during a randomized, double-bind, placebo-controlled trial of pimobendan. Am Heart J. 1992 ; 124 (4). 1017-1025.
-
(1992)
Am Heart J.
, vol.124
, Issue.4
, pp. 1017-1025
-
-
Rector, T.S.1
Cohn, J.N.2
-
17
-
-
0033537699
-
Randomized controlled trial of long-term moderate exercise training in chronic heart failure
-
Belardinelli R., Georgiou D., Cianci G., Purcaro A. Randomized controlled trial of long-term moderate exercise training in chronic heart failure. Effects on functional capacity, quality of life, and clinical outcome. Circulation. 1999 ; 99 (9). 1173-1182.
-
(1999)
Effects on Functional Capacity, Quality of Life, and Clinical Outcome. Circulation
, vol.99
, Issue.9
, pp. 1173-1182
-
-
Belardinelli, R.1
Georgiou, D.2
Cianci, G.3
Purcaro, A.4
-
18
-
-
0026567057
-
Beneficial effects of pimobendan on exercise tolerance and quality of life in patients with heart failure: Results of a multicenter trial
-
Hubo SH, Gollub S., Buorge R., et al. Beneficial effects of pimobendan on exercise tolerance and quality of life in patients with heart failure: results of a multicenter trial. Circulation. 1992 ; 85 (3). 942-949.
-
(1992)
Circulation
, vol.85
, Issue.3
, pp. 942-949
-
-
Hubo, S.H.1
Gollub, S.2
Buorge, R.3
-
19
-
-
0035897696
-
Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
-
Expert Panel on Detection Evaluation Treatment of High Blood Cholesterol in Adults
-
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001 ; 285 (19). 2486-2497.
-
(2001)
JAMA
, vol.285
, Issue.19
, pp. 2486-2497
-
-
-
20
-
-
0037322746
-
Resting heart rate in older people: A predictor of survival to 85
-
Benetos A., Thomas F., Bean K., et al. Resting heart rate in older people: a predictor of survival to 85. J Am Geriatr Soc. 2003 ; 51 (2). 284-285.
-
(2003)
J Am Geriatr Soc
, vol.51
, Issue.2
, pp. 284-285
-
-
Benetos, A.1
Thomas, F.2
Bean, K.3
-
21
-
-
0344394916
-
A single intravenous dose of ivabradine, a novel I(f) inhibitor, lowers heart rate but does not depress left ventricular function in patients with left ventricular dysfunction
-
Manz M., Reuter M., Lauck G., Omran H., Jung W. A single intravenous dose of ivabradine, a novel I(f) inhibitor, lowers heart rate but does not depress left ventricular function in patients with left ventricular dysfunction. Cardiology. 2003 ; 100 (3). 149-155.
-
(2003)
Cardiology
, vol.100
, Issue.3
, pp. 149-155
-
-
Manz, M.1
Reuter, M.2
Lauck, G.3
Omran, H.4
Jung, W.5
-
22
-
-
0037448788
-
Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: A randomized, double-blind, multicentered, placebo-controlled trial
-
Borer JS, Fox K., Jaillon P., Lerebours G. Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: a randomized, double-blind, multicentered, placebo-controlled trial. Circulation. 2003 ; 107 (6). 817-823.
-
(2003)
Circulation
, vol.107
, Issue.6
, pp. 817-823
-
-
Borer, J.S.1
Fox, K.2
Jaillon, P.3
Lerebours, G.4
-
23
-
-
44649184945
-
Favourable effects of heart rate reduction with intravenous administration of ivabradine in patients with advanced heart failure
-
De Ferrari GM, Mazzuero A., Agnesina L., et al. Favourable effects of heart rate reduction with intravenous administration of ivabradine in patients with advanced heart failure. Eur J Heart Fail. 2008 ; 10 (6). 550-555.
-
(2008)
Eur J Heart Fail
, vol.10
, Issue.6
, pp. 550-555
-
-
De Ferrari, G.M.1
Mazzuero, A.2
Agnesina, L.3
-
24
-
-
43249091146
-
Heart rate reduction by ivabradine reduces oxidative stress, improves endothelial function, and prevents atherosclerosis in apolipoprotein E-deficient mice
-
Custodis F., Baumhäkel M., Schlimmer N., et al. Heart rate reduction by ivabradine reduces oxidative stress, improves endothelial function, and prevents atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2008 ; 117 (18). 2377-2387.
-
(2008)
Circulation
, vol.117
, Issue.18
, pp. 2377-2387
-
-
Custodis, F.1
Baumhäkel, M.2
Schlimmer, N.3
-
25
-
-
0025308219
-
Influence of heart rate on mortality after acute myocardial infarction
-
Hjalmarson A., Gilpin EA, Kjekshus J., et al. Influence of heart rate on mortality after acute myocardial infarction. Am J Cardiol. 1990 ; 65 (9). 547-553.
-
(1990)
Am J Cardiol
, vol.65
, Issue.9
, pp. 547-553
-
-
Hjalmarson, A.1
Gilpin, E.A.2
Kjekshus, J.3
-
26
-
-
0036017520
-
Diabetes, heart rate, and mortality
-
Singh N. Diabetes, heart rate, and mortality. J Cardiovasc Pharmacol Ther. 2002 ; 7 (2). 117-129.
-
(2002)
J Cardiovasc Pharmacol Ther
, vol.7
, Issue.2
, pp. 117-129
-
-
Singh, N.1
-
27
-
-
0022505487
-
Effect of timolol on mortality and reinfarction after acute myocardial infarction: Prognostic importance of heart rate at rest
-
Gundersen T., Grottum P., Pedersen T., et al. Effect of timolol on mortality and reinfarction after acute myocardial infarction: prognostic importance of heart rate at rest. Am J Cardiol. 1989 ; 58 (1). 20-24.
-
(1989)
Am J Cardiol
, vol.58
, Issue.1
, pp. 20-24
-
-
Gundersen, T.1
Grottum, P.2
Pedersen, T.3
-
28
-
-
0022541191
-
Importance of heart rate in determining beta-blocker efficacy in acute and long-term acute myocardial infarction intervention trials
-
Kjekshus JK Importance of heart rate in determining beta-blocker efficacy in acute and long-term acute myocardial infarction intervention trials. Am J Cardiol. 1986 ; 57 (12). 43 F-49F.
-
(1986)
Am J Cardiol
, vol.57
, Issue.12
-
-
Kjekshus, J.K.1
-
29
-
-
0023585078
-
Heart rate reduction: A mechanism of benefit?
-
Kjekshus JK Heart rate reduction: a mechanism of benefit? Eur Heart J. 1987 ; 8 (suppl L). 115-122.
-
(1987)
Eur Heart J.
, vol.8
, Issue.SUPPL.
, pp. 115-122
-
-
Kjekshus, J.K.1
-
30
-
-
3743112785
-
Significance of reduction in heart rate in cardiovascular disease
-
Hjalmarson A. Significance of reduction in heart rate in cardiovascular disease. Clin Cardiol. 1998 ; 21 (12 suppl II). 113-117.
-
(1998)
Clin Cardiol
, vol.21
, Issue.12 SUPPL. II
, pp. 113-117
-
-
Hjalmarson, A.1
-
31
-
-
0345866810
-
Effect of graded heart rate reduction with ivabradine on myocardial oxygen consumption and diastolic time in exercising dogs
-
Colin P., Ghaleh B., Monnet X., et al. Effect of graded heart rate reduction with ivabradine on myocardial oxygen consumption and diastolic time in exercising dogs. J Pharmacol Exp Ther. 2004 ; 308 (1). 236-240.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, Issue.1
, pp. 236-240
-
-
Colin, P.1
Ghaleh, B.2
Monnet, X.3
-
32
-
-
0028081393
-
Effects of short and long term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy
-
Metra M., Nardi M., Giubbini R., et al. Effects of short and long term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol. 1994 ; 24 (7). 1678-1687.
-
(1994)
J Am Coll Cardiol
, vol.24
, Issue.7
, pp. 1678-1687
-
-
Metra, M.1
Nardi, M.2
Giubbini, R.3
|