-
2
-
-
0024506159
-
Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway
-
Lindstein, T., C. H. June, J. A. Ledbetter, G. Stella, and C. B. Thompson. 1989. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 244: 339-343.
-
(1989)
Science
, vol.244
, pp. 339-343
-
-
Lindstein, T.1
June, C.H.2
Ledbetter, J.A.3
Stella, G.4
Thompson, C.B.5
-
3
-
-
0031725323
-
Molecular regulation of interleukin-2 expression by CD28 costimulation and anergy
-
Powell, J. D., J. A. Ragheb, S. Kitagawa-Sakakida, and R. H. Schwartz. 1998. Molecular regulation of interleukin-2 expression by CD28 costimulation and anergy. Immunol. Rev. 165: 287-300.
-
(1998)
Immunol. Rev.
, vol.165
, pp. 287-300
-
-
Powell, J.D.1
Ragheb, J.A.2
Kitagawa-Sakakida, S.3
Schwartz, R.H.4
-
4
-
-
0036867423
-
Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus
-
Valenzuela, H. F., and R. B. Effros. 2002. Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus. Clin. Immunol. 105: 117-125.
-
(2002)
Clin. Immunol.
, vol.105
, pp. 117-125
-
-
Valenzuela, H.F.1
Effros, R.B.2
-
5
-
-
0027976958
-
Clonal populations of T cells in normal elderly humans: The T cell equivalent to "benign monoclonal gammapathy"
-
Posnett, D. N., R. Sinha, S. Kabak, and C. Russo. 1994. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy". J. Exp. Med. 179: 609-618.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 609-618
-
-
Posnett, D.N.1
Sinha, R.2
Kabak, S.3
Russo, C.4
-
7
-
-
0035202615
-
Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals
-
Goronzy, J. J., J. W. Fulbright, C. S. Crowson, G. A. Poland, W. M. O'Fallon, and C. M. Weyand. 2001. Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals. J. Virol. 75: 12182-12187.
-
(2001)
J. Virol.
, vol.75
, pp. 12182-12187
-
-
Goronzy, J.J.1
Fulbright, J.W.2
Crowson, C.S.3
Poland, G.A.4
O'Fallon, W.M.5
Weyand, C.M.6
-
8
-
-
0036604275
-
- T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines
-
- T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J. Immunol. 168: 5893-5899.
-
(2002)
J. Immunol.
, vol.168
, pp. 5893-5899
-
-
Saurwein-Teissl, M.1
Lung, T.L.2
Marx, F.3
Gschosser, C.4
Asch, E.5
Blasko, I.6
Parson, W.7
Bock, G.8
Schonitzer, D.9
Trannoy, E.10
Grubeck-Loebenstein, B.11
-
9
-
-
32044433093
-
Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly
-
Hadrup, S. R., J. Strindhall, T. Kollgaard, T. Seremet, B. Johansson, G. Pawelec, P. thor Straten, and A. Wikby. 2006. Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly. J. Immunol. 176: 2645-2653.
-
(2006)
J. Immunol.
, vol.176
, pp. 2645-2653
-
-
Hadrup, S.R.1
Strindhall, J.2
Kollgaard, T.3
Seremet, T.4
Johansson, B.5
Pawelec, G.6
Thor Straten, P.7
Wikby, A.8
-
11
-
-
0028017490
-
Analysis of T-lymphocyte subpopulations in inflammatory bowel diseases by three-color flow cytometry
-
Neil, G. A., R. W. Summers, B. A. Cheyne, C. Carpenter, W. L. Huang, and T. J. Waldschmidt. 1994. Analysis of T-lymphocyte subpopulations in inflammatory bowel diseases by three-color flow cytometry. Dig. Dis. Sci. 39: 1900-1908.
-
(1994)
Dig. Dis. Sci.
, vol.39
, pp. 1900-1908
-
-
Neil, G.A.1
Summers, R.W.2
Cheyne, B.A.3
Carpenter, C.4
Huang, W.L.5
Waldschmidt, T.J.6
-
12
-
-
0031718132
-
Costimulatory molecules in Wegener's granulomatosis (WG): Lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B7-2 (CD86) on T cells
-
DOI 10.1046/j.1365-2249.1998.00695.x
-
Moosig, F., E. Csernok, G. Wang, and W. L. Gross. 1998. Costimulatory molecules in Wegener's granulomatosis (WG): lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B7-2 (CD86) on T cells. Clin. Exp. Immunol. 114: 113-118. (Pubitemid 28442822)
-
(1998)
Clinical and Experimental Immunology
, vol.114
, Issue.1
, pp. 113-118
-
-
Moosig, F.1
Csernok, E.2
Wang, G.3
Gross, W.L.4
-
13
-
-
0030026329
-
Chagasic patients lack CD28 expression on many of their circulating T lymphocytes
-
Dutra, W. O., O. A. Martins-Filho, J. R. Cancado, J. C. Pinto-Dias, Z. Brener, G. Gazzinelli, J. F. Carvalho, and D. G. Colley. 1996. Chagasic patients lack CD28 expression on many of their circulating T lymphocytes. Scand. J. Immunol. 43: 88-93.
-
(1996)
Scand. J. Immunol.
, vol.43
, pp. 88-93
-
-
Dutra, W.O.1
Martins-Filho, O.A.2
Cancado, J.R.3
Pinto-Dias, J.C.4
Brener, Z.5
Gazzinelli, G.6
Carvalho, J.F.7
Colley, D.G.8
-
14
-
-
0029958821
-
- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity
-
- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J. Clin. Invest. 97: 2027-2037.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2027-2037
-
-
Schmidt, D.1
Goronzy, J.J.2
Weyand, C.M.3
-
15
-
-
2942748057
-
From Hayflick to Walford: The role of T cell replicative senescence in human aging
-
DOI 10.1016/j.exger.2004.03.004, PII S0531556504001068
-
Effros, R. B. 2004. From Hayflick to Walford: the role of T cell replicative senescence in human aging. Exp. Gerontol. 39: 885-890. (Pubitemid 38798525)
-
(2004)
Experimental Gerontology
, vol.39
, Issue.6
, pp. 885-890
-
-
Effros, R.B.1
-
16
-
-
1442299281
-
T-cell senescence: A culprit of immune abnormalities in chronic inflammation and persistent infection
-
Vallejo, A. N., C. M. Weyand, and J. J. Goronzy. 2004. T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection. Trends Mol. Med. 10: 119-124.
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 119-124
-
-
Vallejo, A.N.1
Weyand, C.M.2
Goronzy, J.J.3
-
17
-
-
26844513278
-
Modulation of CD28 expression with anti-tumor necrosis factor α therapy in rheumatoid arthritis
-
DOI 10.1002/art.21353
-
Bryl, E., A. N. Vallejo, E. L. Matteson, J. M. Witkowski, C. M. Weyand, and J. J. Goronzy. 2005. Modulation of CD28 expression with anti-tumor necrosis factor α therapy in rheumatoid arthritis. Arthritis Rheum. 52: 2996-3003. (Pubitemid 41447078)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.10
, pp. 2996-3003
-
-
Bryl, E.1
Vallejo, A.N.2
Matteson, E.L.3
Witkowski, J.M.4
Weyand, C.M.5
Goronzy, J.J.6
-
18
-
-
0035884911
-
Down-regulation of CD28 expression by TNF-α
-
Bryl, E., A. N. Vallejo, C. M. Weyand, and J. J. Goronzy. 2001. Down-regulation of CD28 expression by TNF-α. J. Immunol. 167: 3231-3238.
-
(2001)
J. Immunol.
, vol.167
, pp. 3231-3238
-
-
Bryl, E.1
Vallejo, A.N.2
Weyand, C.M.3
Goronzy, J.J.4
-
20
-
-
20344379893
-
CD28 extinction in human T cells: Altered functions and the program of T-cell senescence
-
Vallejo, A. N. 2005. CD28 extinction in human T cells: altered functions and the program of T-cell senescence. Immunol. Rev. 205: 158-169.
-
(2005)
Immunol. Rev.
, vol.205
, pp. 158-169
-
-
Vallejo, A.N.1
-
21
-
-
3142669281
-
Tumor necrosis factor-α and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription
-
Lewis, D. E., M. Merched-Sauvage, J. J. Goronzy, C. M. Weyand, and A. N. Vallejo. 2004. Tumor necrosis factor-α and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription. J. Biol. Chem. 279: 29130-29138.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29130-29138
-
-
Lewis, D.E.1
Merched-Sauvage, M.2
Goronzy, J.J.3
Weyand, C.M.4
Vallejo, A.N.5
-
22
-
-
0037012006
-
Tumor necrosis factor-α-induced apoptosis in T cells from aged humans: A role of TNFR-I and downstream signaling molecules
-
DOI 10.1016/S0531-5565(01)00195-4, PII S0531556501001954
-
Gupta, S. 2002. Tumor necrosis factor-α-induced apoptosis in T cells from aged humans: a role of TNFR-I and downstream signaling molecules. Exp. Gerontol. 37: 293-299. (Pubitemid 34073546)
-
(2002)
Experimental Gerontology
, vol.37
, Issue.2-3
, pp. 293-299
-
-
Gupta, S.1
-
23
-
-
0344874213
-
FasL-induced downregulation of CD28 expression on Jurkat cells in vitro is associated with activation of caspases
-
Ma, S., H. Ochi, L. Cui, and W. He. 2003. FasL-induced downregulation of CD28 expression on Jurkat cells in vitro is associated with activation of caspases. Cell Biol. Int. 27: 959-964.
-
(2003)
Cell Biol. Int.
, vol.27
, pp. 959-964
-
-
Ma, S.1
Ochi, H.2
Cui, L.3
He, W.4
-
24
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
DOI 10.1016/S0092-8674(03)00521-X
-
Micheau, O., and J. Tschopp. 2003. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114: 181-190. (Pubitemid 36936912)
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
25
-
-
0142217368
-
Hydrogen peroxide induced down-regulation of CD28 expression of Jurkat cells is associated with a change of site α-specific nuclear factor binding activity and the activation of caspase-3
-
Ma, S., H. Ochi, L. Cui, J. Zhang, and W. He. 2003. Hydrogen peroxide induced down-regulation of CD28 expression of Jurkat cells is associated with a change of site α-specific nuclear factor binding activity and the activation of caspase-3. Exp. Gerontol. 38: 1109-1118.
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 1109-1118
-
-
Ma, S.1
Ochi, H.2
Cui, L.3
Zhang, J.4
He, W.5
-
26
-
-
0024342791
-
Human T lymphocytes possess a limited in vitro life span
-
Perillo, N. L., R. L. Walford, M. A. Newman, and R. B. Effros. 1989. Human T lymphocytes possess a limited in vitro life span. Exp. Gerontol. 24: 177-187.
-
(1989)
Exp. Gerontol.
, vol.24
, pp. 177-187
-
-
Perillo, N.L.1
Walford, R.L.2
Newman, M.A.3
Effros, R.B.4
-
27
-
-
8444237735
-
+ T cells: Enhanced antiviral functions accompany the increased proliferative potential and telomere length stabilization
-
+ T cells: enhanced antiviral functions accompany the increased proliferative potential and telomere length stabilization. J. Immunol. 173: 6303-6311.
-
(2004)
J. Immunol.
, vol.173
, pp. 6303-6311
-
-
Dagarag, M.1
Evazyan, T.2
Rao, N.3
Effros, R.B.4
-
29
-
-
0028043586
-
+ T cells in centenarians and in long-term T cell cultures: A possible cause for both in vivo and in vitro immunosenescence
-
+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence. Exp. Gerontol. 29: 601-609.
-
(1994)
Exp. Gerontol.
, vol.29
, pp. 601-609
-
-
Effros, R.B.1
Boucher, N.2
Porter, V.3
Zhu, X.4
Spaulding, C.5
Walford, R.L.6
Kronenberg, M.7
Cohen, D.8
Schachter, F.9
-
30
-
-
8944258925
-
+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis
-
+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS 10: F17-F22.
-
(1996)
AIDS
, vol.10
-
-
Effros, R.B.1
Allsopp, R.2
Chiu, C.P.3
Hausner, M.A.4
Hirji, K.5
Wang, L.6
Harley, C.B.7
Villeponteau, B.8
West, M.D.9
Giorgi, J.V.10
-
31
-
-
0032969285
-
Tumor necrosis factor receptor and Fas signaling mechanisms
-
DOI 10.1146/annurev.immunol.17.1.331
-
Wallach, D., E. E. Varfolomeev, N. L. Malinin, Y. V. Goltsev, A. V. Kovalenko, and M. P. Boldin. 1999. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu. Rev. Immunol. 17: 331-367. (Pubitemid 29241128)
-
(1999)
Annual Review of Immunology
, vol.17
, pp. 331-367
-
-
Wallach, D.1
Varfolomeev, E.E.2
Malinin, N.L.3
Goltsev, Y.V.4
Kovalenko, A.V.5
Boldin, M.P.6
-
32
-
-
0031667566
-
Down-regulation of CD28 via Fas (CD95): Influence of CD28 on T-cell apoptosis
-
Walker, L. S., J. D. McLeod, G. Boulougouris, Y. I. Patel, N. D. Hall, and D. M. Sansom. 1998. Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis. Immunology 94: 41-47.
-
(1998)
Immunology
, vol.94
, pp. 41-47
-
-
Walker, L.S.1
McLeod, J.D.2
Boulougouris, G.3
Patel, Y.I.4
Hall, N.D.5
Sansom, D.M.6
-
33
-
-
1642421853
-
Replicative senescence of CD8 T cells: Effect on human ageing
-
Effros, R. B. 2004. Replicative senescence of CD8 T cells: effect on human ageing. Exp. Gerontol. 39: 517-524.
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 517-524
-
-
Effros, R.B.1
-
34
-
-
0032524973
-
Altered cytokine production in the elderly
-
Rink, L., I. Cakman, and H. Kirchner. 1998. Altered cytokine production in the elderly. Mech. Ageing Dev. 102: 199-209.
-
(1998)
Mech. Ageing Dev.
, vol.102
, pp. 199-209
-
-
Rink, L.1
Cakman, I.2
Kirchner, H.3
-
35
-
-
0035915803
-
Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells
-
DOI 10.1016/S0047-6374(00)00199-8, PII S0047637400001998
-
Tarazona, R., O. DelaRosa, C. Alonso, B. Ostos, J. Espejo, J. Pena, and R. Solana. 2000. Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells. Mech. Ageing Dev. 121: 77-88. (Pubitemid 32115402)
-
(2000)
Mechanisms of Ageing and Development
, vol.121
, Issue.1-3
, pp. 77-88
-
-
Tarazona, R.1
Delarosa, O.2
Alonso, C.3
Ostos, B.4
Espejo, J.5
Pea, J.6
Solana, R.7
-
36
-
-
0025827542
-
Influence of age and caloric restriction on macrophage IL-6 and TNF production
-
Effros, R. B., K. Svoboda, and R. L. Walford. 1991. Influence of age and caloric restriction on macrophage IL-6 and TNF production. Lymphokine Cytokine Res. 10: 347-351.
-
(1991)
Lymphokine Cytokine Res
, vol.10
, pp. 347-351
-
-
Effros, R.B.1
Svoboda, K.2
Walford, R.L.3
-
37
-
-
0026061865
-
Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28
-
Fraser, J. D., B. A. Irving, G. R. Crabtree, and A. Weiss. 1991. Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science 251: 313-316.
-
(1991)
Science
, vol.251
, pp. 313-316
-
-
Fraser, J.D.1
Irving, B.A.2
Crabtree, G.R.3
Weiss, A.4
-
38
-
-
0026332710
-
Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element
-
Verweij, C. L., M. Geerts, and L. A. Aarden. 1991. Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element. J. Biol. Chem. 266: 14179-14182.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 14179-14182
-
-
Verweij, C.L.1
Geerts, M.2
Aarden, L.A.3
-
39
-
-
58149192453
-
+ T lymphocytes
-
+ T lymphocytes. J. Immunol. 181: 7400-7406.
-
(2008)
J. Immunol.
, vol.181
, pp. 7400-7406
-
-
Fauce, S.R.1
Jamieson, B.D.2
Chin, A.C.3
Mitsuyasu, R.T.4
Parish, S.T.5
Ng, H.L.6
Kitchen, C.M.7
Yang, O.O.8
Harley, C.B.9
Effros, R.B.10
-
40
-
-
0035525736
-
- compartment
-
- compartment. Blood 98: 2817-2827.
-
(2001)
Blood
, vol.98
, pp. 2817-2827
-
-
Sze, D.M.1
Giesajtis, G.2
Brown, R.D.3
Raitakari, M.4
Gibson, J.5
Ho, J.6
Baxter, A.G.7
De Fazekas St Groth, B.8
Basten, A.9
Joshua, D.E.10
-
42
-
-
0028999584
-
+ T cells from HIV-infected subjects
-
+ T cells from HIV-infected subjects. Clin. Exp. Immunol. 100: 425-433.
-
(1995)
Clin. Exp. Immunol.
, vol.100
, pp. 425-433
-
-
Vingerhoets, J.H.1
Vanham, G.L.2
Kestens, L.L.3
Penne, G.G.4
Colebunders, R.L.5
Vandenbruaene, M.J.6
Goeman, J.7
Gigase, P.L.8
De Boer, M.9
Ceuppens, J.L.10
-
44
-
-
0036383233
-
Biochemotherapy of metastatic malignant melanoma: On down-regulation of CD28
-
Hakansson, A., L. Hakansson, B. Gustafsson, L. Krysander, B. Rettrup, D. Ruiter, and M. R. Bernsen. 2002. Biochemotherapy of metastatic malignant melanoma: on down-regulation of CD28. Cancer Immunol. Immunother. 51: 499-504.
-
(2002)
Cancer Immunol. Immunother.
, vol.51
, pp. 499-504
-
-
Hakansson, A.1
Hakansson, L.2
Gustafsson, B.3
Krysander, L.4
Rettrup, B.5
Ruiter, D.6
Bernsen, M.R.7
-
45
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
Hayflick, L. 1965. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37: 614-636.
-
(1965)
Exp. Cell Res.
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
46
-
-
34147222679
-
Telomerase induction in T cells: A cure for aging and disease?
-
Effros, R. B. 2007. Telomerase induction in T cells: a cure for aging and disease? Exp. Gerontol. 42: 416-420.
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 416-420
-
-
Effros, R.B.1
-
47
-
-
0032845553
-
+ T cells that reach replicative senescence after multiple rounds of antigenspecific proliferation
-
+ T cells that reach replicative senescence after multiple rounds of antigenspecific proliferation. Exp. Gerontol. 34: 633-644.
-
(1999)
Exp. Gerontol.
, vol.34
, pp. 633-644
-
-
Spaulding, C.1
Guo, W.2
Effros, R.B.3
|