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Chemistry - A European Journal

Volumn 17, Issue 2, 2011, Pages 557-563

Engineering the promiscuous racemase activity of an arylmalonate decarboxylase

(4) Kourist, Robert a Miyauchi, Yusuke a Uemura, Daisuke a Miyamoto, Kenji a

a KEIO UNIVERSITY (Japan)

Author keywords

enzymatic promiscuity; enzyme catalysis; protein engineering; racemases

Indexed keywords

CARBON ATOMS; CARBOXYLIC ACID GROUPS; DECARBOXYLASES; DECARBOXYLATION REACTIONS; ENZYMATIC PROMISCUITY; ENZYME CATALYSIS; KETOPROFEN; MOLECULAR DYNAMICS SIMULATIONS; NITRO GROUP; POLAR EFFECT; PROTEIN ENGINEERING; RACEMASE; RACEMASE ACTIVITY; RACEMASES; STEPWISE MECHANISMS; SUBSTRATE PROFILE; SUBSTRATE RANGE; SUBSTRATE STRUCTURE; UNSATURATED CARBOXYLIC ACIDS;

BIOCHEMICAL ENGINEERING; CARBOXYLATION; CARBOXYLIC ACIDS; CATALYSIS; ENZYMES; GENETIC ENGINEERING; ISOMERS; MOLECULAR DYNAMICS; REACTION RATES;

SUBSTRATES;

3 BUTENOIC ACID; 3-BUTENOIC ACID; BUTYRIC ACID DERIVATIVE; CARBOXYLYASE; ISOMERASE; MALONATE DECARBOXYLASE;

ARTICLE; BORDETELLA BRONCHISEPTICA; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; ENZYME SPECIFICITY; ENZYMOLOGY; GENETIC VARIABILITY; GENETICS; METABOLISM; PROTEIN ENGINEERING; SITE DIRECTED MUTAGENESIS; STEREOISOMERISM;

BORDETELLA BRONCHISEPTICA; BUTYRIC ACIDS; CARBOXY-LYASES; CATALYSIS; COMPUTER SIMULATION; GENETIC VARIATION; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; PROTEIN ENGINEERING; RACEMASES AND EPIMERASES; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 78651262164 PISSN: 09476539 EISSN: 15213765 Source Type: Journal
DOI: 10.1002/chem.201001924 Document Type: Article

Times cited : (24)

References (30)

1
- 14744284899
- U. T. Bornscheuer, R. J. Kazlauskas, Angew. Chem. 2004, 116, 6156-6165
- (2004) Angew. Chem. , vol.116 , pp. 6156-6165
- Bornscheuer, U.T.¹ Kazlauskas, R.J.²

2
- 10044248344
- Angew. Chem. Int. Ed. 2004, 43, 6032-6040.
- (2004) Angew. Chem. Int. Ed. , vol.43 , pp. 6032-6040

3
- 34247131307
- K. Hult, P. Berglund, Trends Biotechnol. 2007, 25, 231-238.
- (2007) Trends Biotechnol. , vol.25 , pp. 231-238
- Hult, K.¹ Berglund, P.²

4
- 73149099167
- B. Chen, Z. Cai, W. Wu, Y. L. Huang, J. Pleiss, Z. L. Lin, Biochemistry 2009, 48, 11496-11504.
- (2009) Biochemistry , vol.48 , pp. 11496-11504
- Chen, B.¹ Cai, Z.² Wu, W.³ Huang, Y.L.⁴ Pleiss, J.⁵ Lin, Z.L.⁶

5
- 77149157296
- H. Jochens, K. Stiba, C. Savile, R. Fujii, J. G. Yu, T. Gerassenkov, R. J. Kazlauskas, U. T. Bornscheuer, Angew. Chem. 2009, 121, 3584-3587
- (2009) Angew. Chem. , vol.121 , pp. 3584-3587
- Jochens, H.¹ Stiba, K.² Savile, C.³ Fujii, R.⁴ Yu, J.G.⁵ Gerassenkov, T.⁶ Kazlauskas, R.J.⁷ Bornscheuer, U.T.⁸

6
- 65349103558
- Angew. Chem. Int. Ed. 2009, 48, 3532-3535.
- (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 3532-3535

7
- 53849102182
- K. Okrasa, C. Levy, B. Hauer, N. Baudendistel, D. Leys, J. Micklefield, Chem. Eur. J. 2008, 14, 6609-6613.
- (2008) Chem. Eur. J. , vol.14 , pp. 6609-6613
- Okrasa, K.¹ Levy, C.² Hauer, B.³ Baudendistel, N.⁴ Leys, D.⁵ Micklefield, J.⁶

8
- 33747624943
- Y. Terao, K. Miyamoto, H. Ohta, Chem. Commun. 2006, 3600-3602.
- (2006) Chem. Commun. , pp. 3600-3602
- Terao, Y.¹ Miyamoto, K.² Ohta, H.³

9
- 67650545663
- A. Rubinstein, D. T. Major, J. Am. Chem. Soc. 2009, 131, 8513-8521.
- (2009) J. Am. Chem. Soc. , vol.131 , pp. 8513-8521
- Rubinstein, A.¹ Major, D.T.²

10
- 67749095023
- E. Puig, E. Mixcoha, M. Garcia-Viloca, A. Gonzalez-Lafont, J. M. Lluch, J. Am. Chem. Soc. 2009, 131, 3509-3521.
- (2009) J. Am. Chem. Soc. , vol.131 , pp. 3509-3521
- Puig, E.¹ Mixcoha, E.² Garcia-Viloca, M.³ Gonzalez-Lafont, A.⁴ Lluch, J.M.⁵

11
- 20544439844
- U. Felfer, M. Goriup, M. E. Koegl, U. Wagner, B. Larissegger-Schnell, K. Faber, W. Kroutil, Adv. Synth. Catal. 2005, 347, 951-961.
- (2005) Adv. Synth. Catal. , vol.347 , pp. 951-961
- Felfer, U.¹ Goriup, M.² Koegl, M.E.³ Wagner, U.⁴ Larissegger-Schnell, B.⁵ Faber, K.⁶ Kroutil, W.⁷

12
- 73549112664
- D. Ouazia, S. L. Bearne, Anal. Biochem. 2010, 398, 45-51.
- (2010) Anal. Biochem. , vol.398 , pp. 45-51
- Ouazia, D.¹ Bearne, S.L.²

13
- 0026602064
- A. M. Evans, Eur. J. Clin. Pharmacol. 1992, 42, 237-256.
- (1992) Eur. J. Clin. Pharmacol. , vol.42 , pp. 237-256
- Evans, A.M.¹

14
- 0030737815
- E. J. Ebbers, G. J. A. Ariaans, J. P. M. Houbiers, A. Bruggink, B. Zwanenburg, Tetrahedron 1997, 53, 9417-9476.
- (1997) Tetrahedron , vol.53 , pp. 9417-9476
- Ebbers, E.J.¹ Ariaans, G.J.A.² Houbiers, J.P.M.³ Bruggink, A.⁴ Zwanenburg, B.⁵

15
- 68049111471
- R. J. Kazlauskas, U. T. Bornscheuer, Nat. Chem. Biol. 2009, 5, 526-529.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 526-529
- Kazlauskas, R.J.¹ Bornscheuer, U.T.²

16
- 73349128950
- K. Okrasa, C. Levy, M. Wilding, M. Goodall, N. Baudendistel, B. Hauer, D. Leys, J. Micklefield, Angew. Chem. 2009, 121, 7827-7830
- (2009) Angew. Chem. , vol.121 , pp. 7827-7830
- Okrasa, K.¹ Levy, C.² Wilding, M.³ Goodall, M.⁴ Baudendistel, N.⁵ Hauer, B.⁶ Leys, D.⁷ Micklefield, J.⁸

17
- 70349998462
- Angew. Chem. Int. Ed. 2009, 48, 7691-7694.
- (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 7691-7694

18
- 77749259029
- R. Obata, M. Nakasako, Biochemistry 2010, 49, 1963-1969.
- (2010) Biochemistry , vol.49 , pp. 1963-1969
- Obata, R.¹ Nakasako, M.²

19
- 0016434458
- U. M. Babu, R. B. Johnston, L. C. McNeff, Anal. Biochem. 1975, 63, 208-213.
- (1975) Anal. Biochem. , vol.63 , pp. 208-213
- Babu, U.M.¹ Johnston, R.B.² McNeff, L.C.³

20
- 0032540651
- P. J. Um, D. G. Drueckhammer, J. Am. Chem. Soc. 1998, 120, 5605-5610.
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 5605-5610
- Um, P.J.¹ Drueckhammer, D.G.²

21
- 34047189417
- R. Stuermer, B. Hauer, M. Hall, K. Faber, Curr. Opin. Chem. Biol. 2007, 11, 203-213.
- (2007) Curr. Opin. Chem. Biol. , vol.11 , pp. 203-213
- Stuermer, R.¹ Hauer, B.² Hall, M.³ Faber, K.⁴

22
- 0026488349
- K. Miyamoto, H. Ohta, Eur. J. Biochem. 1992, 210, 475-481.
- (1992) Eur. J. Biochem. , vol.210 , pp. 475-481
- Miyamoto, K.¹ Ohta, H.²

23
- 0035501658
- U. Felfer, U. T. Strauss, W. Kroutil, W. M. F. Fabian, K. Faber, J. Mol. Catal. B: Enzym. 2001, 15, 213-222.
- (2001) J. Mol. Catal. B: Enzym. , vol.15 , pp. 213-222
- Felfer, U.¹ Strauss, U.T.² Kroutil, W.³ Fabian, W.M.F.⁴ Faber, K.⁵

24
- 77952562463
- K. Engström, J. Nyhlen, A. G. Sandström, J. E. Backväll, J. Am. Chem. Soc. 2010, 132, 7038-7042.
- (2010) J. Am. Chem. Soc. , vol.132 , pp. 7038-7042
- Engström, K.¹ Nyhlen, J.² Sandström, A.G.³ Backväll, J.E.⁴

25
- 77958596284
- R. Palkovits, Angew. Chem. 2010, 122, 4434-4436
- (2010) Angew. Chem. , vol.122 , pp. 4434-4436
- Palkovits, R.¹

26
- 77953670758
- Angew. Chem. Int. Ed. 2010, 49, 4336-4338.
- (2010) Angew. Chem. Int. Ed. , vol.49 , pp. 4336-4338

27
- 78651228559
- J.-P. Lange, R. Price, P. M. Ayoub, J. Louis, L. Petrus, L. Clarke, H. Gosselink, Angew. Chem. 2010, 122, 4581-4585
- (2010) Angew. Chem. , vol.122 , pp. 4581-4585
- Lange, J.-P.¹ Price, R.² Ayoub, P.M.³ Louis, J.⁴ Petrus, L.⁵ Clarke, L.⁶ Gosselink, H.⁷

28
- 77953674309
- Angew. Chem. Int. Ed. 2010, 49, 4479-4483.
- (2010) Angew. Chem. Int. Ed. , vol.49 , pp. 4479-4483

29
- 78651233233
- H. Aygün, S. Wojczewski, M. Kircher, S. Rosmus, US 2010/0144010, 2005
- H. Aygün, S. Wojczewski, M. Kircher, S. Rosmus, US 2010/0144010, 2005.

30
- 1842842876
- K. Miyazaki, M. Takenouchi, Biotechniques 2002, 33, 1033-1038.
- (2002) Biotechniques , vol.33 , pp. 1033-1038
- Miyazaki, K.¹ Takenouchi, M.²

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