In vitro efficacy of 7-benzylamino-1-isoquinolinamines against Plasmodium falciparum related to the efficacy of chalcones

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 2, 2011, Pages 786-789

  Gutteridge, Clare E ^a   Hoffman, Marshall M ^a   Bhattacharjee, Apurba K ^b   Milhous, Wilbur K ^b,c   Gerena, Lucia ^b  

^a UNITED STATES NAVAL ACADEMY   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Chalcone; In vitro efficacy; Malaria; Plasmodium; Quinolinamine

Indexed keywords

7 BENZYLAMINO 1 ISOQUINOLINAMINE DERIVATIVE; ANTIMALARIAL AGENT; CHALCONE DERIVATIVE; CHLOROQUINE; DIHYDROFOLATE REDUCTASE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG EFFICACY; ENZYME INHIBITION; IN VITRO STUDY; NONHUMAN; PHARMACOPHORE; PLASMODIUM FALCIPARUM;

AMINOQUINOLINES; ANTIMALARIALS; CHALCONES; CHLOROQUINE; DRUG RESISTANCE; HUMANS; MALARIA, FALCIPARUM; MODELS, MOLECULAR; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM;

EID: 78651243097     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.11.099     Document Type: Article

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