메뉴 건너뛰기




Volumn 32, Issue 1, 2011, Pages 70-78

Amelioration of glomerulosclerosis with all-trans retinoic acid is linked to decreased plasminogen activator inhibitor-1 and α-smooth muscle actin

Author keywords

smooth muscle actin; nephrectomy; plasmin; plasminogen activator inhibitor 1; retinoids

Indexed keywords

ALBUMIN; ALPHA SMOOTH MUSCLE ACTIN; CREATININE; GELATINASE A; PLASMIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; RETINOIC ACID;

EID: 78651103064     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.200     Document Type: Article
Times cited : (13)

References (56)
  • 1
    • 0032512094 scopus 로고    scopus 로고
    • Pathophysiology of progressive nephropathies
    • Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J Med 1998; 339: 1448-56.
    • (1998) N Engl J Med , vol.339 , pp. 1448-1456
    • Remuzzi, G.1    Bertani, T.2
  • 2
    • 0029150795 scopus 로고
    • Proteolytic remodeling of extracellular matrix
    • Birkedal-Hansen H. Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol 1995; 7: 728-35.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 728-735
    • Birkedal-Hansen, H.1
  • 4
    • 0029117124 scopus 로고
    • Myofibroblasts and the progression of experimental glomerulonephritis
    • Zhang G, Moorhead PJ, el Nahas AM. Myofibroblasts and the progression of experimental glomerulonephritis. Exp Nephrol 1995; 3: 308-18.
    • (1995) Exp Nephrol , vol.3 , pp. 308-318
    • Zhang, G.1    Moorhead, P.J.2    El Nahas, A.M.3
  • 5
    • 0025732353 scopus 로고
    • Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation
    • Johnson RJ, Iida H, Alpers CE, Majesky MW, Schwartz SM, Pritzi P, et al. Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest 1991; 87: 847-58.
    • (1991) J Clin Invest , vol.87 , pp. 847-858
    • Johnson, R.J.1    Iida, H.2    Alpers, C.E.3    Majesky, M.W.4    Schwartz, S.M.5    Pritzi, P.6
  • 6
    • 0031011375 scopus 로고    scopus 로고
    • Myofibroblast phenotypes expression in experimental renal scarring
    • Muchaneta-Kubara EC, el Nahas AM. Myofibroblast phenotypes expression in experimental renal scarring. Nephrol Dial Transplant 1997; 12: 904-15.
    • (1997) Nephrol Dial Transplant , vol.12 , pp. 904-915
    • Muchaneta-Kubara, E.C.1    El Nahas, A.M.2
  • 7
    • 0036068351 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and the kidney
    • Eddy AA. Plasminogen activator inhibitor-1 and the kidney. Am J Physiol Renal Physiol 2002; 283: F209-20.
    • (2002) Am J Physiol Renal Physiol , vol.283
    • Eddy, A.A.1
  • 8
    • 0030054203 scopus 로고    scopus 로고
    • Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene
    • Eitzman DT, McCoy RD, Zheng X, Fay WP, Shen T, Ginsburg D, et al. Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene. J Clin Invest 1996; 97: 232-7.
    • (1996) J Clin Invest , vol.97 , pp. 232-237
    • Eitzman, D.T.1    McCoy, R.D.2    Zheng, X.3    Fay, W.P.4    Shen, T.5    Ginsburg, D.6
  • 9
    • 23044445962 scopus 로고    scopus 로고
    • Multifunctionality of PAI-1 in fibrogenesis: Evidence from obstructive nephropathy in PAI-1-overexpressing mice
    • Matsuo S, López-Guisa JM, Cai X, Okamura DM, Alpers CE, Bumgarner RE, et al. Multifunctionality of PAI-1 in fibrogenesis: Evidence from obstructive nephropathy in PAI-1-overexpressing mice. Kidney Int 2005; 67: 2221-38.
    • (2005) Kidney Int , vol.67 , pp. 2221-2238
    • Matsuo, S.1    López-Guisa, J.M.2    Cai, X.3    Okamura, D.M.4    Alpers, C.E.5    Bumgarner, R.E.6
  • 10
    • 0038512474 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 is a significant determinant of renal injury in experimental crescentic glomerulonephritis
    • Kitching AR, Kong YZ, Huang XR, Davenport P, Edgtton KL, Carmeliet P, et al. Plasminogen activator inhibitor-1 is a significant determinant of renal injury in experimental crescentic glomerulonephritis. J Am Soc Nephrol 2003; 14: 1487-95.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1487-1495
    • Kitching, A.R.1    Kong, Y.Z.2    Huang, X.R.3    Davenport, P.4    Edgtton, K.L.5    Carmeliet, P.6
  • 11
    • 0034912450 scopus 로고    scopus 로고
    • PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction
    • Oda T, Jung YO, Kim HS, Cai X, López-Guisa JM, Ikeda Y, et al. PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction. Kidney Int 2001; 60: 587-96.
    • (2001) Kidney Int , vol.60 , pp. 587-596
    • Oda, T.1    Jung, Y.O.2    Kim, H.S.3    Cai, X.4    López-Guisa, J.M.5    Ikeda, Y.6
  • 12
    • 20144386753 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy
    • Nicholas SB, Aguiniga E, Ren Y, Kim J, Wong J, Govindarajan N, et al. Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy. Kidney Int 2005; 67: 1297-307.
    • (2005) Kidney Int , vol.67 , pp. 1297-1307
    • Nicholas, S.B.1    Aguiniga, E.2    Ren, Y.3    Kim, J.4    Wong, J.5    Govindarajan, N.6
  • 13
    • 33644860518 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury
    • Ma J, Weisberg A, Griffin JP, Vaughan DE, Fogo AB, Brown NJ. Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury. Kidney Int 2006; 69: 1064-72.
    • (2006) Kidney Int , vol.69 , pp. 1064-1072
    • Ma, J.1    Weisberg, A.2    Griffin, J.P.3    Vaughan, D.E.4    Fogo, A.B.5    Brown, N.J.6
  • 14
    • 32844468585 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 gene deficiency attenuates TGFbeta1- induced kidney disease
    • Krag S, Danielsen CC, Carmeliet P, Nyengaard J, Wogensen L. Plasminogen activator inhibitor-1 gene deficiency attenuates TGFbeta1- induced kidney disease. Kidney Int 2005; 68: 2651-66.
    • (2005) Kidney Int , vol.68 , pp. 2651-2666
    • Krag, S.1    Danielsen, C.C.2    Carmeliet, P.3    Nyengaard, J.4    Wogensen, L.5
  • 15
    • 0042388115 scopus 로고    scopus 로고
    • A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritis
    • Huang Y, Haraguchi M, Lawrence DA, Border WA, Yu L, Noble NA. A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritis. J Clin Invest 2003; 112: 379-88.
    • (2003) J Clin Invest , vol.112 , pp. 379-388
    • Huang, Y.1    Haraguchi, M.2    Lawrence, D.A.3    Border, W.A.4    Yu, L.5    Noble, N.A.6
  • 16
    • 35348889650 scopus 로고    scopus 로고
    • Effects of pioglitazone and candesartan on renal fibrosis and the intrarenal plasmin cascade in spontaneously hypercholesterolemic rats
    • Omasu F, Oda T, Yamada M, Yoshizawa N, Yamakami K, Sakurai Y, et al. Effects of pioglitazone and candesartan on renal fibrosis and the intrarenal plasmin cascade in spontaneously hypercholesterolemic rats. Am J Physiol Renal Physiol 2007; 293: F1292-8.
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Omasu, F.1    Oda, T.2    Yamada, M.3    Yoshizawa, N.4    Yamakami, K.5    Sakurai, Y.6
  • 18
    • 0037693895 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
    • Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry. Circ Res 2003; 92: 827-39.
    • (2003) Circ Res , vol.92 , pp. 827-839
    • Visse, R.1    Nagase, H.2
  • 19
    • 0028945629 scopus 로고
    • ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/MMP-2 cascade
    • Baricos WH, Cortez SL, el-Dahr SS, Schnaper HW. ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/MMP-2 cascade. Kidney Int 1995; 47: 1039-47.
    • (1995) Kidney Int , vol.47 , pp. 1039-1047
    • Baricos, W.H.1    Cortez, S.L.2    El-Dahr, S.S.3    Schnaper, H.W.4
  • 20
    • 21244473728 scopus 로고    scopus 로고
    • 13-cis retinoic acid inhibits development and progression of chronic allograft nephropathy
    • Adams J, Kiss E, Arroyo AB, Bonrouhi M, Sun Q, Li Z, et al. 13-cis retinoic acid inhibits development and progression of chronic allograft nephropathy. Am J Pathol 2005; 167: 285-98.
    • (2005) Am J Pathol , vol.167 , pp. 285-298
    • Adams, J.1    Kiss, E.2    Arroyo, A.B.3    Bonrouhi, M.4    Sun, Q.5    Li, Z.6
  • 22
    • 0042191695 scopus 로고    scopus 로고
    • Retinoid agonist isotretinoin ameliorates obstructive renal injury
    • Schaier M, Jocks T, Grone HJ, Ritz E, Wagner J. Retinoid agonist isotretinoin ameliorates obstructive renal injury. J Urol 2003; 170: 1398-402.
    • (2003) J Urol , vol.170 , pp. 1398-1402
    • Schaier, M.1    Jocks, T.2    Grone, H.J.3    Ritz, E.4    Wagner, J.5
  • 23
    • 0037378798 scopus 로고    scopus 로고
    • Retinoids regulate the repairing process of the podocytes in puromycin aminonucleoside-induced nephrotic rats
    • Suzuki A, Ito T, Imai E, Yamato M, Iwatani H, Kawachi H, et al. Retinoids regulate the repairing process of the podocytes in puromycin aminonucleoside-induced nephrotic rats. J Am Soc Nephrol 2003; 14: 981-91.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 981-991
    • Suzuki, A.1    Ito, T.2    Imai, E.3    Yamato, M.4    Iwatani, H.5    Kawachi, H.6
  • 24
    • 24944563923 scopus 로고    scopus 로고
    • ATRA induces podocyte differentiation and alters nephrin and podocin expression in vitro and in vivo
    • Vaughan MR, Pippin JW, Griffin SV, Krofft R, Fleet M, Haseley L, et al. ATRA induces podocyte differentiation and alters nephrin and podocin expression in vitro and in vivo. Kidney Int 2005; 68: 133-44.
    • (2005) Kidney Int , vol.68 , pp. 133-144
    • Vaughan, M.R.1    Pippin, J.W.2    Griffin, S.V.3    Krofft, R.4    Fleet, M.5    Haseley, L.6
  • 25
  • 27
    • 57849113915 scopus 로고    scopus 로고
    • Chronic low-dose isotretinoin treatment limits renal damage in subtotally nephrectomized rats
    • Morath C, Ratzlaff K, Dechow C, Schwenger V, Schaier M, Zeier B, et al. Chronic low-dose isotretinoin treatment limits renal damage in subtotally nephrectomized rats. J Mol Med 2009; 87: 53-64.
    • (2009) J Mol Med , vol.87 , pp. 53-64
    • Morath, C.1    Ratzlaff, K.2    Dechow, C.3    Schwenger, V.4    Schaier, M.5    Zeier, B.6
  • 28
    • 0034758667 scopus 로고    scopus 로고
    • Effects of retinoids on the TGF-beta system and extracellular matrix in experimental glomerulonephritis
    • Morath C, Dechow C, Lehrke I, Haxsen V, Waldherr R, Floege J, et al. Effects of retinoids on the TGF-beta system and extracellular matrix in experimental glomerulonephritis. J Am Soc Nephrol 2001; 12: 2300-9.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2300-2309
    • Morath, C.1    Dechow, C.2    Lehrke, I.3    Haxsen, V.4    Waldherr, R.5    Floege, J.6
  • 29
    • 0141788781 scopus 로고    scopus 로고
    • Chronic all-trans retinoic acid treatment prevents medial thickening of intramyocardial and intrarenal arteries in spontaneously hypertensive rats
    • Lü L, Yao T, Zhu YZ, Huang GY, Cao YX, Zhu YC. Chronic all-trans retinoic acid treatment prevents medial thickening of intramyocardial and intrarenal arteries in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2003; 285: H1370-7.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Lü, L.1    Yao, T.2    Zhu, Y.Z.3    Huang, G.Y.4    Cao, Y.X.5    Zhu, Y.C.6
  • 30
    • 51349144771 scopus 로고    scopus 로고
    • All-trans retinoic acid inhibits the increases in fibronectin and PAI-1 induced by TGF-beta1 and Ang II in rat mesangial cells
    • Liu X, Lü L, Tao BB, Zhu YC. All-trans retinoic acid inhibits the increases in fibronectin and PAI-1 induced by TGF-beta1 and Ang II in rat mesangial cells. Acta Pharmacol Sin 2008; 29: 1035-41.
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 1035-1041
    • Liu, X.1    Lü, L.2    Tao, B.B.3    Zhu, Y.C.4
  • 31
    • 0021179653 scopus 로고
    • Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats
    • Raij L, Azar S, Keane W. Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats. Kidney Int 1984; 26: 137-43.
    • (1984) Kidney Int , vol.26 , pp. 137-143
    • Raij, L.1    Azar, S.2    Keane, W.3
  • 32
    • 0034090910 scopus 로고    scopus 로고
    • Functional and structural correlates of glomerulosclerosis after renal mass reduction in the rat
    • Griffin KA, Picken MM, Churchill M, Churchill P, Bidani AK. Functional and structural correlates of glomerulosclerosis after renal mass reduction in the rat. J Am Soc Nephrol 2000; 11: 497-506.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 497-506
    • Griffin, K.A.1    Picken, M.M.2    Churchill, M.3    Churchill, P.4    Bidani, A.K.5
  • 33
    • 1942503350 scopus 로고    scopus 로고
    • Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: Strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory
    • Gonçalves AR, Fujihara CK, Mattar AL, Malheiros DM, Noronha Ide L, de Nucci G, et al. Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: Strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory. Am J Physiol Renal Physiol 2004; 286: F945-54.
    • (2004) Am J Physiol Renal Physiol , vol.286
    • Gonçalves, A.R.1    Fujihara, C.K.2    Mattar, A.L.3    Malheiros, D.M.4    Noronha Ide, L.5    De Nucci, G.6
  • 34
    • 0041810638 scopus 로고    scopus 로고
    • The role of arterial hypertension in the progression of non-diabetic glomerular diseases
    • Ljutic D, Kes P. The role of arterial hypertension in the progression of non-diabetic glomerular diseases. Nephrol Dial Transplant 2003; 18: V28-30.
    • (2003) Nephrol Dial Transplant , vol.18
    • Ljutic, D.1    Kes, P.2
  • 35
  • 36
    • 0037207471 scopus 로고    scopus 로고
    • Cell biology of the glomerular podocyte
    • Pavenstädt H, Kriz W, Kretzler M. Cell biology of the glomerular podocyte. Physiol Rev 2003; 83: 253-307.
    • (2003) Physiol Rev , vol.83 , pp. 253-307
    • Pavenstädt, H.1    Kriz, W.2    Kretzler, M.3
  • 37
    • 33745058119 scopus 로고    scopus 로고
    • The podocyte's response to injury: Role in proteinuria and glomerulosclerosis
    • Shankland SJ. The podocyte's response to injury: Role in proteinuria and glomerulosclerosis. Kidney Int 2006; 69: 2131-47.
    • (2006) Kidney Int , vol.69 , pp. 2131-2147
    • Shankland, S.J.1
  • 38
    • 1642350993 scopus 로고    scopus 로고
    • Cellular responses to protein overload: Key event in renal disease progression
    • Zoja C, Benigni A, Remuzzi G. Cellular responses to protein overload: Key event in renal disease progression. Curr Opin Nephrol Hypertens 2004; 13: 31-7.
    • (2004) Curr Opin Nephrol Hypertens , vol.13 , pp. 31-37
    • Zoja, C.1    Benigni, A.2    Remuzzi, G.3
  • 39
    • 0029116262 scopus 로고
    • Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney
    • Lee LK, Meyer TW, Pollock AS, Lovett DH. Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney. J Clin Invest 1995; 96: 953-64.
    • (1995) J Clin Invest , vol.96 , pp. 953-964
    • Lee, L.K.1    Meyer, T.W.2    Pollock, A.S.3    Lovett, D.H.4
  • 40
    • 0033861755 scopus 로고    scopus 로고
    • Retinoid receptors: Pathways of proliferation inhibition and apoptosis induction in breast cancer cell lines
    • Raffo P, Emionite L, Colucci L, Belmondo F, Moro MG, Bollag W, et al. Retinoid receptors: Pathways of proliferation inhibition and apoptosis induction in breast cancer cell lines. Anticancer Res 2000; 20: 1535-43.
    • (2000) Anticancer Res , vol.20 , pp. 1535-1543
    • Raffo, P.1    Emionite, L.2    Colucci, L.3    Belmondo, F.4    Moro, M.G.5    Bollag, W.6
  • 42
    • 0027972156 scopus 로고
    • Anti-AP-1 activity of all-trans retinoic acid in glomerular mesangial cells
    • Simonson MS. Anti-AP-1 activity of all-trans retinoic acid in glomerular mesangial cells. Am J Physiol 1994; 267: F805-15.
    • (1994) Am J Physiol , vol.267
    • Simonson, M.S.1
  • 43
    • 0035970623 scopus 로고    scopus 로고
    • Retinoids inhibit the actions of angiotensin II on vascular smooth muscle cells
    • Haxsen V, Adam-Stitah S, Ritz E, Wagner J. Retinoids inhibit the actions of angiotensin II on vascular smooth muscle cells. Circ Res 2001; 88: 637-44.
    • (2001) Circ Res , vol.88 , pp. 637-644
    • Haxsen, V.1    Adam-Stitah, S.2    Ritz, E.3    Wagner, J.4
  • 44
    • 0032558415 scopus 로고    scopus 로고
    • All-trans-retinoic acid reduces neointimal formation and promotes favorable geometric remodeling of the rat carotid artery after balloon withdrawal injury
    • Miano JM, Kelly LA, Artacho CA, Nuckolls TA, Piantedosi R, Blaner WS. All-trans-retinoic acid reduces neointimal formation and promotes favorable geometric remodeling of the rat carotid artery after balloon withdrawal injury. Circulation 1998; 98: 1219-27.
    • (1998) Circulation , vol.98 , pp. 1219-1227
    • Miano, J.M.1    Kelly, L.A.2    Artacho, C.A.3    Nuckolls, T.A.4    Piantedosi, R.5    Blaner, W.S.6
  • 45
    • 26244432422 scopus 로고    scopus 로고
    • Hepatocyte growth factor receptor signaling mediates the anti-fibrotic action of 9-cis-retinoic acid in glomerular mesangial cells
    • Wen X, Li Y, Hu K, Dai C, Liu Y. Hepatocyte growth factor receptor signaling mediates the anti-fibrotic action of 9-cis-retinoic acid in glomerular mesangial cells. Am J Pathol 2005; 167: 947-57.
    • (2005) Am J Pathol , vol.167 , pp. 947-957
    • Wen, X.1    Li, Y.2    Hu, K.3    Dai, C.4    Liu, Y.5
  • 46
    • 0034999371 scopus 로고    scopus 로고
    • T-PA promotes glomerular plasmin generation and matrix degradation in experimental glomerulonephritis
    • Haraguchi M, Border WA, Huang Y, Noble NA. t-PA promotes glomerular plasmin generation and matrix degradation in experimental glomerulonephritis. Kidney Int 2001; 59: 2146-55.
    • (2001) Kidney Int , vol.59 , pp. 2146-2155
    • Haraguchi, M.1    Border, W.A.2    Huang, Y.3    Noble, N.A.4
  • 47
    • 8044260254 scopus 로고    scopus 로고
    • Plasminogen and plasminogen activators protect against renal injury in crescentic glomerulonephritis
    • Kitching AR, Holdsworth SR, Ploplis VA, Plow EF, Collen D, Carmeliet P, et al. Plasminogen and plasminogen activators protect against renal injury in crescentic glomerulonephritis. J Exp Med 1997; 185: 963-8.
    • (1997) J Exp Med , vol.185 , pp. 963-968
    • Kitching, A.R.1    Holdsworth, S.R.2    Ploplis, V.A.3    Plow, E.F.4    Collen, D.5    Carmeliet, P.6
  • 48
    • 0036854980 scopus 로고    scopus 로고
    • Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy
    • Yang J, Shultz RW, Mars WM, Wegner RE, Li Y, Dai C, et al. Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy. J Clin Invest 2002; 110: 1525-38.
    • (2002) J Clin Invest , vol.110 , pp. 1525-1538
    • Yang, J.1    Shultz, R.W.2    Mars, W.M.3    Wegner, R.E.4    Li, Y.5    Dai, C.6
  • 50
    • 15844379355 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 (gelatinase A) regulates glomerular mesangial cell proliferation and differentiation
    • Turck J, Pollock AS, Lee LK, Marti HP, Lovett DH. Matrix metalloproteinase 2 (gelatinase A) regulates glomerular mesangial cell proliferation and differentiation. J Biol Chem 1996; 271: 15074-83.
    • (1996) J Biol Chem , vol.271 , pp. 15074-15083
    • Turck, J.1    Pollock, A.S.2    Lee, L.K.3    Marti, H.P.4    Lovett, D.H.5
  • 51
    • 0038582623 scopus 로고    scopus 로고
    • Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation
    • Cheng S, Lovett DH. Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation. Am J Pathol 2003; 162: 1937-49.
    • (2003) Am J Pathol , vol.162 , pp. 1937-1949
    • Cheng, S.1    Lovett, D.H.2
  • 52
    • 33947233187 scopus 로고    scopus 로고
    • Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: Role of plasmin-activated signals
    • Zhang G, Kernan KA, Collins SJ, Cai X, López-Guisa JM, Degen JL, et al. Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: Role of plasmin-activated signals. J Am Soc Nephrol 2007; 18: 846-59.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 846-859
    • Zhang, G.1    Kernan, K.A.2    Collins, S.J.3    Cai, X.4    López-Guisa, J.M.5    Degen, J.L.6
  • 53
    • 0032521250 scopus 로고    scopus 로고
    • Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice
    • Ploplis VA, French EL, Carmeliet P, Collen D, Plow EF. Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice. Blood 1998; 91: 2005-9.
    • (1998) Blood , vol.91 , pp. 2005-2009
    • Ploplis, V.A.1    French, E.L.2    Carmeliet, P.3    Collen, D.4    Plow, E.F.5
  • 54
    • 0035188403 scopus 로고    scopus 로고
    • Maximizing hemodynamic-independent effects of angiotensin II antagonists in fibrotic diseases
    • Border WA, Noble N. Maximizing hemodynamic-independent effects of angiotensin II antagonists in fibrotic diseases. Semin Nephrol 2001; 21: 563-72.
    • (2001) Semin Nephrol , vol.21 , pp. 563-572
    • Border, W.A.1    Noble, N.2
  • 55
    • 33847725009 scopus 로고    scopus 로고
    • Therapeutic potential of TGF-beta inhibition in chronic renal failure
    • Gagliardini E, Benigni A. Therapeutic potential of TGF-beta inhibition in chronic renal failure. Expert Opin Biol Ther 2007; 7: 293-304.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 293-304
    • Gagliardini, E.1    Benigni, A.2
  • 56
    • 0031932140 scopus 로고    scopus 로고
    • Link between angiotensin II and TGF-beta in the kidney
    • Wolf G. Link between angiotensin II and TGF-beta in the kidney. Miner Electrolyte Metab 1998; 24: 174-80.
    • (1998) Miner Electrolyte Metab , vol.24 , pp. 174-180
    • Wolf, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.