Biochemical and spectroscopic characterization of almond and cashew nut seed 11S legumins, amandin and anacardein

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 1, 2011, Pages 386-393

  Kshirsagar, Harshal H ^a,b   Fajer, Piotr ^a   Sharma, Girdhari M ^a   Roux, Kenneth H ^a   Sathe, Shridhar K ^a,c  

^a FLORIDA STATE UNIVERSITY   (United States)

^b Roquette America Inc   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Amandin; anacardein; antibodies; denaturation; fluorescence; immunoreactivity; protein structure

Indexed keywords

AMANDIN; ANACARDEIN; CASHEW NUT; IMMUNOREACTIVITIES; MERCAPTOETHANOL; MONOCLONAL ANTIBODIES (MABS); PROTEIN STRUCTURE; RANDOM COIL; SECONDARY STRUCTURES; SODIUM DODECYL SULFATE; SPECTROSCOPIC CHARACTERIZATION; STRUCTURAL CHANGE;

FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; MONOCLONAL ANTIBODIES; SODIUM; SODIUM SULFATE; UREA;

DENATURATION;

AMANTADINE; PEPTIDE; VEGETABLE PROTEIN;

ARTICLE; CASHEW NUT; CHEMISTRY; CIRCULAR DICHROISM; IMMUNOLOGY; PLANT SEED; PROTEIN SECONDARY STRUCTURE; PRUNUS; SPECTROFLUOROMETRY;

ANACARDIUM; CIRCULAR DICHROISM; PEPTIDES; PLANT PROTEINS; PROTEIN STRUCTURE, SECONDARY; PRUNUS; SEEDS; SPECTROMETRY, FLUORESCENCE;

ANACARDIUM OCCIDENTALE; PRUNUS DULCIS;

EID: 78651089143     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf1030899     Document Type: Article

References (62)

1. Sicherer, S. H.; Munoz-Furlong, A.; Godbold, J. H.; Sampson, H. A. US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow-up J. Allergy Clin. Immunol. 2010, 126, 1322-1326
2. FAO. http://faostat.fao.org/site/343/default.aspx, FAO statistical database, 2010.
3. Ahn, K.; Bardina, L.; Grishina, G.; Beyer, K.; Sampson, H. A. Identification of two pistachio allergens, Pis v 1 and Pis v 2, belonging to the 2S albumin and 11S globulin family Clin. Exp. Allergy 2009, 39 (6) 926-934
4. Sathe, S. K.; Kshirsagar, H. H.; Roux, K. H. Advances in seed protein research: a perspective on seed allergens J. Food Sci. 2005, 70, R93-R120
5. Tawde, P.; Venkatesh, Y. P.; Wang, F.; Teuber, S. S.; Sathe, S. K.; Roux, K. H. Cloning and characterization of profilin (Pru du 4), a cross-reactive almond (Prunus dulcis) allergen J. Allergy Clin. Immunol. 2006, 118 (4) 915-922
6. Wallowitz, M.; Peterson, W. R.; Uratsu, S.; Comstock, S. S.; Dandekar, A. M.; Teuber, S. S. Jug r 4, a legumin group food allergen from walnut (Juglans regia Cv. Chandler) J. Agric. Food Chem. 2006, 54 (21) 8369-8375
7. Willison, L. N.; Tawde, P.; Robotham, J. M.; Penney, R. M.; Teuber, S. S.; Sathe, S. K.; Roux, K. H. Pistachio vicilin, Pis v 3, is immunoglobulin E-reactive and cross-reacts with the homologous cashew allergen, Ana o 1 Clin. Exp. Allergy 2008, 38 (7) 1229-1238
8. Venkatachalam, M.; Sathe, S. K. Chemical composition of selected edible nut seeds J. Agric. Food Chem. 2006, 54 (13) 4705-4714
9. Sathe, S. K.; Wolf, W. J.; Roux, K. H.; Teuber, S. S.; Venkatachalam, M.; Sze-Tao, K. W. Biochemical characterization of amandin, the major storage protein in almond (Prunus dulcis L.) J. Agric. Food Chem. 2002, 50 (15) 4333-4341
10. Sharma, G. M.; Mundoma, C.; Seavy, M.; Roux, K. H.; Sathe, S. K. Purification and biochemical characterization of Brazil nut (Bertholletia excelsa L.) seed storage proteins J. Agric. Food Chem. 2010, 58 (9) 5714-5723
11. Sun, S. S. M.; Leung, F. W.; Tomic, J. C. Brazil nut (Bertholletia excelsa H. B. K.) proteins: fractionation, composition, and identification of a sulfur-rich protein J. Agric. Food Chem. 1987, 35, 232-235
12. Shokraii, E. H.; Esen, A. Composition, solubility, and electrophoretic patterns of proteins isolated from kerman pistachio nuts (Pistacia vera L.) J. Agric. Food Chem. 1988, 36 (3) 425-429
13. Sathe, S. K. Solubilization and electrophoretic characterization of cashew nut (Anacardium occidentale L.) proteins Food Chem. 1994, 51, 319-324
14. Sze-Tao, K. W. C.; Sathe, S. K. Walnuts (Juglans regia L.): proximate composition, protein solubility, protein amino acid composition, and protein in vitro digestibility J. Sci. Food Agic. 2000, 80, 1393-1401
15. Venkatachalam, M.; Roux, K. H.; Sathe, S. K. Biochemical characterization of soluble proteins in pecan [ Carya illinoinensis (Wangenh.) K. Koch] J. Agric. Food Chem. 2008, 56 (17) 8103-8110
16. Dunwell, J. M. Cupins: a new superfamily of functionally diverse proteins that include germins and plant storage proteins Biotechnol. Genet. Eng Rev. 1998, 15, 1-32
17. Roux, K. H.; Teuber, S. S.; Robotham, J. M.; Sathe, S. K. Detection and stability of the major almond allergen in foods J. Agric. Food Chem. 2001, 49 (5) 2131-2136
18. Sathe, S. K.; Teuber, S. S.; Gradziel, T. M.; Roux, K. H. Electrophoretic and immunological analyses of almond (Prunus dulcis l.) genotypes and hybrids J. Agric. Food Chem. 2001, 49 (4) 2043-2052
19. Beyer, K.; Bardina, L.; Grishina, G.; Grishina, A.; Sampson, H. A. Identification of a new Brazil nut allergen Ber e 2 J. Allergy Clin. Immunol. 2008, 121 (2) S247
20. Wang, F.; Robotham, J. M.; Teuber, S. S.; Sathe, S. K.; Roux, K. H. Ana o 2, a major cashew (Anacardium occidentale L.) nut allergen of the legumin family Int. Arch. Allergy Immunol. 2003, 132 (1) 27-39
21. Rabjohn, P.; Helm, E. M.; Stanley, J. S.; West, C. M.; Sampson, H. A.; Burks, A. W.; Bannon, G. A. Molecular cloning and epitope analysis of the peanut allergen Ara h 3 J. Clin. Invest. 1999, 103 (4) 535-542
22. Beyer, K.; Grishina, G.; Bardina, L.; Grishin, A.; Sampson, H. A. Identification of an 11S globulin as a major hazelnut food allergen in hazelnut-induced systemic reactions J. Allergy Clin. Immunol. 2002, 110 (3) 517-523
23. Malley, A.; Baecher, L.; Mackler, B.; Perlman, F. The isolation of allergens from the green pea J. Allergy Clin. Immunol. 1975, 56 (4) 282-290
24. Teuber, S. S.; Peterson, W. R. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens J. Allergy Clin. Immunol. 1999, 103 (6) 1180-1185
25. Sathe, S. K.; Sze-Tao, K. W. C.; Wolf, W. J.; Hamaker, B. R. Biochemical characterization and in vitro digestibility of the major globulin in cashew nut (Anacardium occidentale) J. Agric. Food Chem. 1997, 45, 2854-2860
26. Su, M.; Venkatachalam, M.; Teuber, S. S.; Roux, K. H.; Sathe, S. K. Impact of γ-irradiation and thermal processing on the antigenicity of almond, cashew nut and walnut proteins J. Sci. Food Agric. 2004, 84 (10) 1119-1125
27. Venkatachalam, M.; Teuber, S. S.; Roux, K. H.; Sathe, S. K. Effects of roasting, blanching, autoclaving, and microwave heating on antigenicity of almond (Prunus dulcis L.) proteins J. Agric. Food Chem. 2002, 50 (12) 3544-3548
28. Venkatachalam, M.; Monaghan, E. K.; Kshirsagar, H. H.; Robotham, J. M.; O'Donnell, S. E.; Gerber, M. S.; Roux, K. H.; Sathe, S. K. Effects of processing on immunoreactivity of cashew nut (Anacardium occidentale L.) seed flour proteins J. Agric. Food Chem. 2008, 56 (19) 8998-9005
29. Gruber, P.; Vieths, S.; Wangorsch, A.; Nerkamp, J.; Hofmann, T. Maillard reaction and enzymatic browning affect the allergenicity of Pru av 1, the major allergen from cherry (Prunus avium) J. Agric. Food Chem. 2004, 52 (12) 4002-4007
30. Jenkins, J. A.; Griffiths-Jones, S.; Shewry, P. R.; Breiteneder, H.; Mills, E. N. Structural relatedness of plant food allergens with specific reference to cross-reactive allergens: an in silico analysis J. Allergy Clin. Immunol. 2005, 115 (1) 163-170
31. Maleki, S. J.; Kopper, R. A.; Shin, D. S.; Park, C. W.; Compadre, C. M.; Sampson, H.; Burks, A. W.; Bannon, G. A. Structure of the major peanut allergen Ara h 1 may protect IgE-binding epitopes from degradation J. Immunol. 2000, 164 (11) 5844-5849
32. Robotham, J. M.; Xia, L.; Willison, L. N.; Teuber, S. S.; Sathe, S. K.; Roux, K. H. Characterization of a cashew allergen, 11S globulin (Ana o 2), conformational epitope Mol. Immunol. 2010, 47 (9) 1830-1838
33. Xia, L.; Willison, L. N.; Porter, L.; Robotham, J. M.; Teuber, S. S.; Sathe, S. K.; Roux, K. H. Mapping of a conformational epitope on the cashew allergen Ana o 2: a discontinuous large subunit epitope dependent upon homologous or heterologous small subunit association Mol. Immunol. 2010, 47 (9) 1808-1816
34. Padavattan, S.; Flicker, S.; Schirmer, T.; Madritsch, C.; Randow, S.; Reese, G.; Vieths, S.; Lupinek, C.; Ebner, C.; Valenta, R.; Markovic-Housley, Z. High-affinity IgE recognition of a conformational epitope of the major respiratory allergen Phl p 2 as revealed by X-ray crystallography J. Immunol. 2009, 182 (4) 2141-2151
35. Lakowicz, J. R. Principles of Fluorescence Spectroscopy, 2 nd ed.; Kluwer Academic/Plenum Publishers: New York, 1999; p 698.
36. Fling, S. P.; Gregerson, D. S. Peptide and protein molecular weight determination by electrophoresis using a high-molarity tris buffer system without urea Anal. Biochem. 1986, 155 (1) 83-88
37. Sathe, S. K. Solubilization, electrophoretic characterization and in vitro digestibility of almond (Prunus amygdalus) proteins J. Food Biochem. 1993, 16, 249-264
38. Wei, Y.; Sathe, S. K.; Teuber, S. S.; Roux, K. H. A sensitive sandwich ELISA for the detection of trace amounts of cashew (Anacardium occidentale L.) nut in foods J. Agric. Food Chem. 2003, 51 (11) 3215-3221
39. Gaur, V.; Sethi, D. K.; Salunke, D. M. Purification, identification and preliminary crystallographic studies of Pru du amandin, an allergenic protein from Prunus dulcis Acta Crystallogr. Sect. F: Struct. Biol. Cryst. Commun. 2008, 64 (Part 1) 32-35
40. Clara Sze, K. W.; Kshirsagar, H. H.; Venkatachalam, M.; Sathe, S. K. A circular dichroism and fluorescence spectrometric assessment of effects of selected chemical denaturants on soybean (Glycine max L.) storage proteins glycinin (11S) and β-conglycinin (7S) J. Agric. Food Chem. 2007, 55 (21) 8745-8753
41. Dev, S. B.; Keller, J. T.; Rha, C. K. Secondary structure of 11S globulin in aqueous solution investigated by FT-IR derivative spectroscopy Biochim. Biophys. Acta 1988, 957 (2) 272-280
42. Albillos, S. M.; Menhart, N.; Fu, T. J. Structural stability of Amandin, a major allergen from almond (Prunus dulcis), and its acidic and basic polypeptides J. Agric. Food Chem. 2009, 57 (11) 4698-4705
43. Lakemond, C. M.; de Jongh, H. H.; Hessing, M.; Gruppen, H.; Voragen, A. G. Soy glycinin: influence of pH and ionic strength on solubility and molecular structure at ambient temperatures J. Agric. Food Chem. 2000, 48 (6) 1985-1990 (Pubitemid 30431176)
44. Altschuler, E. L.; Hud, N. V.; Mazrimas, J. A.; Rupp, B. Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides J. Pept. Res. 1997, 50 (1) 73-75
45. Masino, L.; Pastore, A. Glutamine repeats: structural hypotheses and neurodegeneration Biochem. Soc. Trans. 2002, 30 (4) 548-551
46. Adachi, M.; Kanamori, J.; Masuda, T.; Yagasaki, K.; Kitamura, K.; Mikami, B.; Utsumi, S. Crystal structure of soybean 11S globulin: glycinin A3B4 homohexamer Proc. Natl. Acad. Sci. U. S.A. 2003, 100 (12) 7395-7400
47. Mills, E. N.; Marigheto, N. A.; Wellner, N.; Fairhurst, S. A.; Jenkins, J. A.; Mann, R.; Belton, P. S. Thermally induced structural changes in glycinin, the 11S globulin of soya bean (Glycine max) - an in situ spectroscopic study Biochim. Biophys. Acta 2003, 1648 (1-2) 105-114
48. Helm, R. M.; Cockrell, G.; Connaughton, C.; Sampson, H. A.; Bannon, G. A.; Beilinson, V.; Nielsen, N. C.; Burks, A. W. A soybean G2 glycinin allergen. 2. Epitope mapping and three-dimensional modeling Int. Arch. Allergy Immunol. 2000, 123 (3) 213-219
49. Woody, R. W. Theory of circular dichroism of proteins. In Circular Dichroism and the Conformational Analysis of Biomolecules; Fasman, G. D., Ed.; Plenum Press: New York, 1996; pp 25 - 67.
50. Chandra, B. R. S.; Prakash, V.; Rao, M. S. N. Association dissociation of glycinin in urea, guanidine-hydrochloride and sodium dodecyl-sulfate solutions J. Biosci. 1985, 9, 177-184
51. Reynolds, J. A.; Tanford, C. The gross conformation of protein-sodium dodecyl sulfate complexes J. Biol. Chem. 1970, 245 (19) 5161-5165
52. Towbin, H.; Staehelin, T.; Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications Proc. Natl. Acad. Sci. U.S.A. 1979, 76 (9) 4350-4354
53. Chung, C. M.; Chiu, J. D.; Connors, L. H.; Gursky, O.; Lim, A.; Dykstra, A. B.; Liepnieks, J.; Benson, M. D.; Costello, C. E.; Skinner, M.; Walsh, M. T. Thermodynamic stability of a kappaI immunoglobulin light chain: relevance to multiple myeloma Biophys. J. 2005, 88 (6) 4232-4242
54. Ma, Y. Z.; Tsou, C. L. Comparison of the activity and conformation changes of lactate dehydrogenase H4 during denaturation by guanidinium chloride Biochem. J. 1991, 277 (Part 1) 207-211
55. Xiao, J.; Liang, S. J.; Tsou, C. L. Inactivation before significant conformational change during denaturation of papain by guanidine hydrochloride Biochim. Biophys. Acta 1993, 1164 (1) 54-60
56. Plaxco, K. W.; Spitzfaden, C.; Campbell, I. D.; Dobson, C. M. A comparison of the folding kinetics and thermodynamics of two homologous fibronectin type III modules J. Mol. Biol. 1997, 270 (5) 763-770
57. Nnanna, I. A.; Gupta, S. V. Purification and partial characterization of oat bran globulin J. Agric. Food Chem. 1996, 44 (11) 3494-3499
58. Bennion, B. J.; Daggett, V. The molecular basis for the chemical denaturation of proteins by urea Proc. Natl. Acad. Sci. U.S.A. 2003, 100 (9) 5142-5147
59. Itri, R.; Caetano, W.; Barbosa, L. R. S.; Baptista, M. S. Effect of urea on bovine serum albumin in aqueous and reverse micelle environments investigated by small angle X-ray scattering, fluorescence and circular dichroism Braz. J. Phys. 2004, 34 (1) 58-63
60. Scholtz, J. M.; Barrick, D.; York, E. J.; Stewart, J. M.; Baldwin, R. L. Urea unfolding of peptide helices as a model for interpreting protein unfolding Proc. Natl. Acad. Sci. U.S.A. 1995, 92 (1) 185-189
61. Tobi, D.; Elber, R.; Thirumalai, D. The dominant interaction between peptide and urea is electrostatic in nature: a molecular dynamics simulation study Biopolymers 2003, 68 (3) 359-369
62. Montserret, R.; McLeish, M. J.; Bockmann, A.; Geourjon, C.; Penin, F. Involvement of electrostatic interactions in the mechanism of peptide folding induced by sodium dodecyl sulfate binding Biochemistry 2000, 39 (29) 8362-8373