Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel

Brazilian Journal of Pharmaceutical Sciences

Volumn 46, Issue 3, 2010, Pages 473-481

  Chaud, Marco Vinicius ^a,b   Tamascia, Pollyanna ^b   de Lima, Andreäa Cristina ^c   Paganelli, Maria Ondina ^b   Gremiäo, Maria Palmira Daflon ^c   de Freitas, Osvaldo ^d  

^a UNIVERSITY OF SOROCABA   (Brazil)

^b METHODIST UNIVERSITY OF PIRACICABA   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Praziquantel dissolution rates; Praziquantel intestinal absorption; Praziquantel solubility; Solid dispersion

Indexed keywords

HYDROGENATED CASTOR OIL; PRAZIQUANTEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL PROCEDURES; CONTROLLED STUDY; DISPERSION; DISSOLUTION; DRUG SOLUBILITY; FUSION METHOD; IN VITRO STUDY; INTESTINE ABSORPTION; MALE; NONHUMAN; PARTICLE SIZE; PH; PRECIPITATION; RAT; SMALL INTESTINE; SOLID DISPERSION; SOLUBILIZATION; THERMAL ANALYSIS; WETTABILITY;

EID: 78651068892     PISSN: 19848250     EISSN: 21759790     Source Type: Journal    
DOI: 10.1590/s1984-82502010000300010     Document Type: Article

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