Making ends meet in mycobacteria

Molecular Microbiology

Volumn 79, Issue 2, 2011, Pages 283-287

  Warner, Digby F ^a   Mizrahi, Valerie ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL PROTEIN; EXODEOXYRIBONUCLEASE V; HELICASE; NUCLEASE; PROTEIN ADNAB; UNCLASSIFIED DRUG;

BACTERIAL CHROMOSOME; BACTERIAL METABOLISM; BACTERIAL VIRULENCE; BACTERIUM MUTANT; DNA REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; HOMOLOGOUS RECOMBINATION; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; NONHUMAN; NOTE; NUCLEIC ACID RENATURATION; PHENOTYPE; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION;

CHROMOSOMES, BACTERIAL; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA, BACTERIAL; EXODEOXYRIBONUCLEASE V; MYCOBACTERIUM SMEGMATIS; REC A RECOMBINASES; RECOMBINATION, GENETIC;

CORYNEBACTERINEAE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 78651064595     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2010.07462.x     Document Type: Note

References (32)

1. Ambur, O.H., Davidsen, T., Frye, S.A., Balasingham, S.V., Lagesen, K., Rognes, T., and Tonjum, T. (2009) Genome dynamics in major bacterial pathogens. FEMS Microbiol Rev 33: 453-470.
2. Amundsen, S.K., Fero, J., Hansen, L.M., Cromie, G.A., Solnick, J.V., Smith, G.R., and Salama, N.R. (2008) Helicobacter pylori AddAB helicase-nuclease and RecA promote recombination-related DNA repair and survival during stomach colonization. Mol Microbiol 69: 994-1007.
3. Aniukwu, J., Glickman, M.S., and Shuman, S. (2008) The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends. Genes Dev 22: 512-527.
4. Boshoff, H.I., Reed, M.B., Barry, C.E., 3rd, and Mizrahi, V. (2003) DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis. Cell 113: 183-193.
5. Buchmeier, N.A., Lipps, C.J., So, M.Y., and Heffron, F. (1993) Recombination-deficient mutants of Salmonella typhimurium are avirulent and sensitive to the oxidative burst of macrophages. Mol Microbiol 7: 933-936.
6. Chedin, F., and Kowalczykowski, S.C. (2002) A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination. Mol Microbiol 43: 823-834.
7. Cole, S.T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., et al. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544.
8. Colleaux, L., D'Auriol, L., Galibert, F., and Dujon, B. (1988) Recognition and cleavage site of the intron-encoded omega transposase. Proc Natl Acad Sci USA 85: 6022-6026.
9. Darwin, K.H., and Nathan, C.F. (2005) Role for nucleotide excision repair in virulence of Mycobacterium tuberculosis. Infect Immun 73: 4581-4587.
10. Della, M., Palmbos, P.L., Tseng, H.M., Tonkin, L.M., Daley, J.M., Topper, L.M., et al. (2004) Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine. Science 306: 683-685.
11. Dutta, N.K., Mehra, S., Didier, P.J., Roy, C.J., Doyle, L.A., Alvarez, X., et al. (2010) Genetic requirements for the survival of tubercle bacilli in primates. J Infect Dis 201: 1743-1752.
12. Gong, C., Bongiorno, P., Martins, A., Stephanou, N.C., Zhu, H., Shuman, S., and Glickman, M.S. (2005) Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C. Nat Struct Mol Biol 12: 304-312.
13. Gorna, A.E., Bowater, R.P., and Dziadek, J. (2010) DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection. Clin Sci (Lond) 119: 187-202.
14. Guo, Y., Bandaru, V., Jaruga, P., Zhao, X., Burrows, C.J., Iwai, S., et al. (2010) The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts. DNA Repair (Amst) 9: 177-190.
15. Gupta, R., Barkan, D., Redelman-Sidi, G., Shuman, S., and Glickman, M.S. (2011) Mycobacteria exploit three genetically distinct DNA double-strand break repair pathways. Mol Microbiol 79: 316-330.
16. Kana, B.D., Abrahams, G.L., Sung, N., Warner, D.F., Gordhan, B.G., Machowski, E.E., et al. (2010) Role of the DinB Homologs, Rv1537 and Rv3056, in Mycobacterium tuberculosis. J Bacteriol 192: 2220-2227.
17. Kha, D.T., Wang, G., Natrajan, N., Harrison, L., and Vasquez, K.M. (2010) Pathways for double-strand break repair in genetically unstable Z-DNA-forming sequences. J Mol Biol 398: 471-480.
18. Mizrahi, V., and Andersen, S.J. (1998) DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence? Mol Microbiol 29: 1331-1339.
19. Rachman, H., Strong, M., Ulrichs, T., Grode, L., Schuchhardt, J., Mollenkopf, H., et al. (2006) Unique transcriptome signature of Mycobacterium tuberculosis in pulmonary tuberculosis. Infect Immun 74: 1233-1242.
20. Russell, D.G., Barry, C.E., 3rd, and Flynn, J.L. (2010) Tuberculosis: what we don't know can, and does, hurt us. Science 328: 852-856.
21. Sassetti, C.M., and Rubin, E.J. (2003) Genetic requirements for mycobacterial survival during infection. Proc Natl Acad Sci USA 100: 12989-12994.
22. Schnappinger, D., Ehrt, S., Voskuil, M.I., Liu, Y., Mangan, J.A., Monahan, I.M., et al. (2003) Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J Exp Med 198: 693-704.
23. Sinha, K.M., Stephanou, N.C., Gao, F., Glickman, M.S., and Shuman, S. (2007) Mycobacterial UvrD1 is a Ku-dependent DNA helicase that plays a role in multiple DNA repair events, including double-strand break repair. J Biol Chem 282: 15114-15125.
24. Sinha, K.M., Unciuleac, M.C., Glickman, M.S., and Shuman, S. (2009) AdnAB: a new DSB-resecting motor-nuclease from mycobacteria. Genes Dev 23: 1423-1437.
25. Stallings, C.L., Stephanou, N.C., Chu, L., Hochschild, A., Nickels, B.E., and Glickman, M.S. (2009) CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence. Cell 138: 146-159.
26. Stephanou, N.C., Gao, F., Bongiorno, P., Ehrt, S., Schnappinger, D., Shuman, S., and Glickman, M.S. (2007) Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks. J Bacteriol 189: 5237-5246.
27. Talaat, A.M., Lyons, R., Howard, S.T., and Johnston, S.A. (2004) The temporal expression profile of Mycobacterium tuberculosis infection in mice. Proc Natl Acad Sci USA 101: 4602-4607.
28. Unciuleac, M.C., and Shuman, S. (2010a) Characterization of the mycobacterial AdnAB DNA motor provides insights into the evolution of bacterial motor-nuclease machines. J Biol Chem 285: 2632-2641.
29. Unciuleac, M.C., and Shuman, S. (2010b) Double-strand break unwinding and resection by the mycobacterial helicase-nuclease AdnAB in the presence of mycobacterial SSB. J Biol Chem 285: 34319-34329.
30. Warner, D.F. (2010) The role of DNA repair in M. tuberculosis pathogenesis. Drug Discov Today Dis Mech 7: e5-e11.
31. Warner, D.F., Ndwandwe, D.E., Abrahams, G.L., Kana, B.D., Machowski, E.E., Venclovas, C., and Mizrahi, V. (2010) Essential roles for imuA'- and imuB-encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis. Proc Natl Acad Sci USA 107: 13093-13098.
32. Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., and Shuman, S. (2006) Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D. Proc Natl Acad Sci USA 103: 1711-1716.