The opening of maitotoxin-sensitive calcium channels induces the acrosome reaction in human spermatozoa: Differences from the zona pellucida

Asian Journal of Andrology

Volumn 13, Issue 1, 2011, Pages 159-165

  Chávez, Julio C ^a   De Blas, Gerardo A ^a   De La Vega Beltrán, José L ^a   Nishigaki, Takuya ^a   Chirinos, Mayel ^b   González González, María Elena ^b   Larrea, Fernando ^b   Solís, Alejandra ^a   Darszon, Alberto ^a   Trevĩo, Claudia L ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^b INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

acrosome reaction; calcium channels; human sperm; maitotoxin; mouse sperm

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; CALCIUM CHANNEL; CALCIUM ION; EDELFOSINE; GLYCOPROTEIN; MAITOTOXIN; PHOSPHOLIPASE C; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; ZONA PELLUCIDA 3 PROTEIN; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; ESTRANE DERIVATIVE; MARINE TOXIN; OXOCIN DERIVATIVE;

ACROSOME REACTION; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; ENZYME INHIBITION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; SPERMATOZOON CAPACITATION; ZONA PELLUCIDA; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SPERMATOZOON;

ACROSOME REACTION; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; ESTRENES; HUMANS; MALE; MARINE TOXINS; MICE; OXOCINS; PYRROLIDINONES; SIGNAL TRANSDUCTION; SPERM CAPACITATION; SPERMATOZOA; TYPE C PHOSPHOLIPASES; ZONA PELLUCIDA;

EID: 78650983320     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2010.80     Document Type: Article

References (34)

1. Takahashi M, Ohizumi Y, Yasumoto T. Maitotoxin, a Ca21 channel activator candidate. J Biol Chem 1982; 257: 7287-9.
2. Escobar LI, Salvador C, Martinez M, Vaca L. Maitotoxin, a cationic channel activator. Neurobiology (Bp) 1998; 6: 59-74.
3. Gutierrez D, Diaz de Leon L, Vaca L. Characterization of the maitotoxin-induced calcium influx pathway from human skin fibroblasts. Cell Calcium 1997; 22: 31-8.
4. Brereton HM, Chen J, Rychkov G, Harland ML, Barritt GJ. Maitotoxin activates an endogenous non-selective cation channel and is an effective initiator of the activation of the heterologously expressed hTRPC-1 (transient receptor potential) non-selective cation channel in H4-IIE liver cells. Biochim Biophys Acta 2001; 1540; 107-26.
5. Chen J, Barritt GJ. Evidence that TRPC1 (transient receptor potential canonical 1) forms a Ca21-permeable channel linked to the regulation of cell volume in liver cells obtained using small interfering RNA targeted against TRPC1. Biochem J 2003; 373: 327-36.
6. Trevino CL, de la Vega-Beltran JL, Nishigaki T, Felix R, Darszon A. Maitotoxin potently promotes Ca21 influx in mouse spermatogenic cells and sperm, and induces the acrosome reaction. J Cell Physiol 2006; 206: 449-56.
7. Sinkins WG, Estacion M, Prasad V, Goel M, Shull GE et al. Maitotoxin converts the plasmalemmal Ca21 pump into a Ca21-permeable nonselective cation channel. Am J Physiol Cell Physiol 2009; 297: C1533-43.
8. Darszon A, Acevedo JJ, Galindo BE, Hernandez-Gonzalez EO, Nishigaki T et al. Sperm channel diversity and functional multiplicity. Reproduction 2006; 131: 977-88.
9. Xia J, Ren D. The BSA-induced Ca21 influx during sperm capacitation is CATSPER channel-dependent. Reprod Biol Endocrinol 2009; 7: 119.
10. Jungnickel MK, Marrero H, Birnbaumer L, Lemos JR, Florman HM. Trp2 regulates entry of Ca21 into mouse sperm triggered by egg ZP3. Nat Cell Biol 2001; 3: 499-502.
11. Chiu PC, Wong BS, Chung MK, Lam KK, Pang RT et al. Effects of native human zona pellucida glycoproteins 3 and 4 on acrosome reaction and zona pellucida binding of human spermatozoa. Biol Reprod 2008; 79: 869-77.
12. Kirkman-Brown JC, Bray C, Stewart PM, Barratt CL, Publicover SJ. Biphasic elevation of [Ca21]i in individual human spermatozoa exposed to progesterone. Dev Biol 2000; 222: 326-35.
13. Moore GD, Ayabe T, Visconti PE, Schultz RM, Kopf GS. Roles of heterotrimeric and monomeric G proteins in sperm-induced activation of mouse eggs. Development 1994; 120: 3313-23.
14. World Health Organization. WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. New York: Cambridge University Press; 1999.
15. Bleil JD, Wassarman PM. Autoradiographic visualization of the mouse eggs sperm receptor bound to sperm. J Cell Biol 1986; 102: 1363-71.
16. Munoz-Garay C, de la Vega-Beltran JL, Delgado R, Labarca P, Felix R et al. Inwardly rectifying K1 channels in spermatogenic cells: functional expression and implication in sperm capacitation. Dev Biol 2001; 234: 261-74.
17. Mendoza C, Carreras A, Moos J, Tesarik J. Distinction between true acrosome reaction and degenerative acrosome loss by a one-step staining method using Pisum sativum agglutinin. J Reprod Fertil 1992; 95: 755-63.
18. Caballero-Campo P, Chirinos M, Fan XJ, Gonzalez-Gonzalez ME, Galicia-Chavarria M et al. Biological effects of recombinant human zona pellucida proteins on sperm function. Biol Reprod 2006; 74: 760-8.
19. Nishigaki T, Wood CD, Shiba K, Baba SA, Darszon A. Stroboscopic illumination using light-emitting diodes reduces phototoxicity in fluorescence cell imaging. Biotechniques 2006; 41: 191-7.
20. Estacion M, Schilling WP. Blockade of maitotoxin-induced oncotic cell death reveals zeiosis. BMC Physiol 2002; 2: 2.
21. Evdonin AL, Guzhova IV, Margulis BA, Medvedeva ND. Phospholipase c inhibitor, u73122, stimulates release of hsp-70 stress protein from A431 human carcinoma cells. Cancer Cell Int 2004; 4: 2.
22. Mogami H, Lloyd Mills C, Gallacher DV. Phospholipase C inhibitor, U73122, releases intracellular Ca21, potentiates Ins(1,4,5)P3-mediated Ca21 release and directly activates ion channels in mouse pancreatic acinar cells. Biochem J 1997; 324 (Part 2): 645-51.
23. Naito Y, Okada M, Yagisawa H. Phospholipase C isoforms are localized at the cleavage furrow during cytokinesis. J Biochem 2006; 140: 785-91.
24. Wong R, Fabian L, Forer A, Brill JA. Phospholipase C and myosin light chain kinase inhibition define a common step in actin regulation during cytokinesis. BMC Cell Biol 2007; 8: 15.
25. Shimizu T, Yamaguchi N, Okada S, Lu L, Sasaki T et al. Roles of brain phosphatidylinositol-specific phospholipase C and diacylglycerol lipase in centrally administered histamine-induced adrenomedullary outflow in rats. Eur J Pharmacol 2007; 571: 138-44.
26. Apostolakos P, Panteris E, Galatis B. The involvement of phospholipases C and D in the asymmetric division of subsidiary cell mother cells of Zea mays. Cell Motil Cytoskeleton 2008; 65: 863-75.
27. Horowitz LF, Hirdes W, Suh BC, Hilgemann DW, Mackie K et al. Phospholipase C in living cells: activation, inhibition, Ca21 requirement, and regulation of M current. J Gen Physiol 2005; 126: 243-62.
28. Jin W, Lo TM, Loh HH, Thayer SA. U73122 inhibits phospholipase C-dependent calcium mobilization in neuronal cells. Brain Res 1994; 642: 237-43.
29. Fukami K, Nakao K, Inoue T, Kataoka Y, Kurokawa M et al. Requirement of phospholipase Cdelta4 for the zona pellucida-induced acrosome reaction. Science 2001; 292: 920-3.
30. Baxendale RW, Fraser LR. Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa. Mol Reprod Dev 2003; 66: 181-9.
31. Baxendale RW, Fraser LR. Immunolocalization of multiple Galpha subunits in mammalian spermatozoa and additional evidence for Galphas. Mol Reprod Dev 2003; 65: 104-13.
32. Breitbart H. Signaling pathways in sperm capacitation and acrosome reaction. Cell Mol Biol (Noisy-le-grand) 2003; 49: 321-7.
33. Venant A, Dazy AC, Diogene G, Metezeau P, Marano F. Effects of maitotoxin on calcium entry and phosphoinositide breakdown in the rabbit ciliated tracheal epithelium. Biol Cell 1994; 82: 195-202.
34. Satoh E, Ishii T, Nishimura M. The mechanism of maitotoxin-induced elevation of the cytosolic free calcium level in rat cerebrocortical synaptosomes. Jpn J Pharmacol 2001; 85: 98-100.