Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa

Molecular Reproduction and Development

Volumn 66, Issue 2, 2003, Pages 181-189

  Baxendale, Rhona W ^a   Fraser, Lynn R ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Capacitation; G proteins; Immunolocalization; mAC; sAC

Indexed keywords

ADENYLATE CYCLASE; ADENYLYL CYCLASE 1; ADENYLYL CYCLASE 2; ADENYLYL CYCLASE 3; ADENYLYL CYCLASE 4; ANTIBODY; CELL SURFACE RECEPTOR; CYCLIC AMP; FLUORIDE SODIUM; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (2 THIODIPHOSPHATE); GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOENZYME; MASTOPARAN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ACROSOME; ANIMAL CELL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; ENZYME ACTIVITY; FERTILIZATION; FLAGELLUM; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPERMATOZOON; SPERMATOZOON CAPACITATION; SPERMATOZOON TAIL; WESTERN BLOTTING;

ADENYLATE CYCLASE; ANIMALS; CYCLIC AMP; DIDEOXYADENOSINE; FORSKOLIN; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; ISOENZYMES; MALE; MICE; PEPTIDES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; SODIUM FLUORIDE; SPERM CAPACITATION; SPERMATOZOA; THIONUCLEOTIDES; WASP VENOMS;

MAMMALIA;

EID: 0042856454     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.10344     Document Type: Article

References (37)

1. Adeoya-Osiguwa SA, Fraser LR. 2000. Fertilization promoting peptide and adenosine, acting as first messengers, regulate cAMP production and consequent protein tyrosine phosphorylation in a capacitation-dependent manner. Mol Reprod Dev 57:384-392.
2. Adeoya-Osiguwa SA, Fraser LR. 2002. Capacitation state-dependent changes in adenosine receptors and their regulation of adenylyl cyclase/cAMP. Mol Reprod Dev 63:245-255.
3. Adeoya-Osiguwa SA, Fraser LR. 2003. Calcitonin acts as a first messenger to regulate adenylyl cyclase/cAMP and mammalian sperm function. Mol Reprod Dev 65:228-236.
4. Adeoya-Osiguwa SA, Dudley RK, Hosseini R, Fraser LR. 1998. FPP modulates mammalian sperm function via TCP-11 and the adenylyl cyclase pathway. Mol Reprod Dev 51:468-476.
5. s. Mol Reprod Dev 65:104-113.
6. Buck J, Sinclair ML, Schapal L, Cann MJ, Levin LR. 1999. Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals. Proc Natl Acad Sci 96:79-84.
7. Chen Y, Cann MJ, Litvin TN, Iourgenko V, Sinclair ML, Levin LR, Buck J. 2000. Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor. Science 289:625-628.
8. De Lamirande E, Leclerc P, Gagnon C. 1997. Capacitation as a regulatory event that primes spermatozoa for the acrosome reaction and fertilization. Mol Hum Reprod 3:175-194.
9. Defer N, Marinx O, Poyard M, Lienard MO, Jegou B, Hanoune J. 1998. The olfactory adenylyl cyclase type 3 is expressed in male germ cells. FEBS Lets 424:216-220.
10. Defer N, Best-Belpomme M, Hanoune J. 2000. Tissue specificity and physiological relevance of various iseforms of adenylyl cyclase. Am J Physiol Renal Physiol 279:F400-F416.
11. Dessauer CW, Tesmer JJJG, Sprand SR, Gilman AG. 1999. The interactions of adenylate cyclases with P-site inhibitors. Trends Pharmacol Sci 20:205-210.
12. Forte LR, Bylund DB, Zahler WL. 1983. Forskolin does not activate sperm adenylate cyclase. Mol Pharmacol 24:42-47.
13. Fraser LR. 1993. In vitro capacitation and fertilization. Methods Enzymol 225:239-253.
14. Fraser LR, Adeoya-Osiguwa S. 1999. Modulation of adenylyl cyclase by FPP and adenosine involves stimulatory and inhibitory adenosine receptors and G proteins. Mol Reprod Dev 53:459-471.
15. 2 receptors bind to mouse spermatozoa and stimulate adenylate cyclase activity in uncapacitated suspensions. J Reprod Fertil 98:187-194.
16. Fraser LR, Hosseini R, Hanyalogou A, Talmor A, Dudley RK. 1997. TCP-11, the product of a mouse t-complex gene, plays a role in stimulation of capacitation and inhibition of the spontaneous acrosome reaction. Mol Reprod Dev 48:375-382.
17. Funahashi H, Fujiwara T, Nagai T. 2000. Modulation of the function of boar spermatozoa via adenosine and fertilization promoting peptide receptors reduce the incidence of polyspermic penetration into porcine oocytes. Biol Reprod 63:1157-1163.
18. Gautier-Courteille C, Salanova M, Conti M. 1998. The olfactory adenynyl cyclase III is expressed in rat germ cells during spermiogenesis. Endocrinology 139:2588-2599.
19. Green CM, Cockle SM, Watson PF, Fraser LR. 1994. Stimulating effect of pyroglutamylglutamylprolineamide, a prostatic, TRH-related tripeptide, on mouse sperm capacitation and fertilizing ability in vitro. Mol Reprod Dev 38:215-221.
20. Hanoune J, Defer N. 2001. Regulation and role of adenylyl cyclase isoforms. Ann Rev Pharm Toxicol 41:145-174.
21. Hanski E, Garty NB. 1983. Activation of adenylate cyclase by sperm membranes. The role of guanine nucleotide binding proteins. FEBS Lets 162:447-452,
22. Hildebrandt JD, Codina J, Tash JS, Kirchick HJ, Lipschultz L, Sekura RD, Birnbaumer L. 1985. The membrane-bound spermatozoal adenylyl cyclase system does not share coupling characteristics with somatic cell adenylyl cyclases. Endocrinology 116:1357-1366.
23. Hurley JH. 1999. Structure, mechanism and regulation of mammalian adenylyl cyclases. J Biol Chem 274:7599-7602.
24. Jaiswal BS, Conti M. 2001. Identification and functional analysis of splice variants of the germ cell soluble adenylyl cyclase. J Biol Chem 276:31698-31708.
25. Johnson RA, Desaubry L, Bianchi G, Shoshani I, Lyons E, Jr., Taussig R, Watson PA, Cali JJ, Krupinski J, Pieroni JP, Iyengar R. 1997. Isozyme-dependent sensitivity of adenylyl cyclases to P-site-mediated inhibition by adenine nucleosides and nucleoside 3′-polyphosphates. J Biol Chem 272:8962-8966.
26. Leclerc P, Kopf GS. 1995. Mouse sperm adenylyl cyclase: General properties and regulation by the zona pellucida. Biol Reprod 52:1227-1233.
27. Leclerc P, Kopf GS. 1999. Evidence for the role of heterotrimeric guanine nucleotide-binding regulatory proteins in the regulation of the mouse sperm adenylyl cyclase by the egg's zona pellucida. J Androl 20:126-134.
28. Luconi M, Barni T, Vannelli GB, Krausz C, Marra F, Benedetti PA, Evangelista V, Francavilla S, Properzi G, Forti G, Baldi E. 1998. Extracellular signal-regulated kinases modulate capacitation of human spermatozoa. Biol Reprod 58:1476-1489.
29. Palmer TM, Stiles GL. 1995. Adenosine receptors. Neuropharmacology 34:683-694.
30. Snedecor GW, Cochran WG. 1980. Statistical methods, 7th edition. Ames: Iowa State University.
31. Stein DM, Fraser LR. 1984. Cyclic nucleotide metabolism in mouse epididymal spermatozoa during capacitation in vitro. Gam Res 10:283-299.
32. Stein DM, Fraser LR, Monks NJ. 1986. Adenosine and Gpp(NH)p modulate mouse sperm adenylyl cyclase. Gam Res 13:151-158.
33. sα and forskolin. Science 268:1769-1772.
34. Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M. 1993. Olfactory receptors are displayed on dog mature sperm cells. J Cell Biol 123:1441-1452.
35. Walensky LD, Roskams AJ, Lefkowitz RJ, Snyder SH, Ronnett GV. 1995. Odorant receptors and desensitization proteins colocalize in mammalian sperm. Mol Med 1:130-141.
36. Wuttke MS, Buck J, Levin LR. 2001. Bicarbonate-regulated soluble adenylyl cyclase. J Pancreas 2(Suppl 4):154-158.
37. sα- and forskolin-activated enzyme in vitro. J Biol Chem 271:10941-10945.