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Volumn 71, Issue 2, 2011, Pages 207-223

Evaluation of limited sampling methods for estimation of tacrolimus exposure in adult kidney transplant recipients

Author keywords

Area under the concentration time curve; Bayesian forecasting; Kidney transplantation; Limited sampling strategy; Multiple regression; Tacrolimus

Indexed keywords

MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; TACROLIMUS;

EID: 78650975256     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2010.03815.x     Document Type: Article
Times cited : (47)

References (69)
  • 1
    • 78650977111 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Services. U.S. organ procurement and transplantation network and the scientific registry of transplant recipients. Available at (last accessed 18 August 2009).
    • U.S. Department of Health and Human Services. U.S. organ procurement and transplantation network and the scientific registry of transplant recipients. Available at (last accessed 18 August 2009).
  • 3
    • 3242772986 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation
    • Staatz CE, Tett SE. Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation. Clin Pharmacokinet 2004; 43: 623-53.
    • (2004) Clin Pharmacokinet , vol.43 , pp. 623-53
    • Staatz, C.E.1    Tett, S.E.2
  • 4
    • 19544378313 scopus 로고    scopus 로고
    • Immunosuppressive drug monitoring - what to use in clinical practice today to improve renal graft outcome
    • Kuypers DR. Immunosuppressive drug monitoring - what to use in clinical practice today to improve renal graft outcome. Transpl Int 2005; 18: 140-50.
    • (2005) Transpl Int , vol.18 , pp. 140-50
    • Kuypers, D.R.1
  • 5
    • 0036913473 scopus 로고    scopus 로고
    • Population pharmacokinetics of tacrolimus in adult kidney transplant recipients
    • Staatz CE, Willis C, Taylor PJ, Tett SE. Population pharmacokinetics of tacrolimus in adult kidney transplant recipients. Clin Pharmacol Ther 2002; 72: 660-9.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 660-9
    • Staatz, C.E.1    Willis, C.2    Taylor, P.J.3    Tett, S.E.4
  • 8
    • 0242332169 scopus 로고    scopus 로고
    • Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients
    • Thervet E, Anglicheau D, King B, Schlageter MH, Cassinat B, Beaune P, Legendre C, Daly AK. Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients. Transplantation 2003; 76: 1233-5.
    • (2003) Transplantation , vol.76 , pp. 1233-5
    • Thervet, E.1    Anglicheau, D.2    King, B.3    Schlageter, M.H.4    Cassinat, B.5    Beaune, P.6    Legendre, C.7    Daly, A.K.8
  • 9
    • 14044278166 scopus 로고    scopus 로고
    • Tacrolimus pharmacogenetics: the CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians
    • Macphee IA, Fredericks S, Mohamed M, Moreton M, Carter ND, Johnston A, Goldberg L, Holt DW. Tacrolimus pharmacogenetics: the CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and South Asians. Transplantation 2005; 79: 499-502.
    • (2005) Transplantation , vol.79 , pp. 499-502
    • Macphee, I.A.1    Fredericks, S.2    Mohamed, M.3    Moreton, M.4    Carter, N.D.5    Johnston, A.6    Goldberg, L.7    Holt, D.W.8
  • 11
    • 0036851317 scopus 로고    scopus 로고
    • Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy
    • Shimada T, Terada A, Yokogawa K, Kaneko H, Nomura M, Kaji K, Kaneko S, Kobayashi K, Miyamoto K. Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy. Transplantation 2002; 74: 1419-24.
    • (2002) Transplantation , vol.74 , pp. 1419-24
    • Shimada, T.1    Terada, A.2    Yokogawa, K.3    Kaneko, H.4    Nomura, M.5    Kaji, K.6    Kaneko, S.7    Kobayashi, K.8    Miyamoto, K.9
  • 20
    • 0034999251 scopus 로고    scopus 로고
    • Comparative tacrolimus pharmacokinetics: normal versus mildly hepatically impaired subjects
    • Bekersky I, Dressler D, Alak A, Boswell GW, Mekki QA. Comparative tacrolimus pharmacokinetics: normal versus mildly hepatically impaired subjects. J Clin Pharmacol 2001; 41: 628-35.
    • (2001) J Clin Pharmacol , vol.41 , pp. 628-35
    • Bekersky, I.1    Dressler, D.2    Alak, A.3    Boswell, G.W.4    Mekki, Q.A.5
  • 24
    • 0031833481 scopus 로고    scopus 로고
    • Factors affecting the pharmacokinetics of tacrolimus in the first year after renal transplantation. European Tacrolimus Multicentre Renal Study Group
    • Undre NA, Schafer A. Factors affecting the pharmacokinetics of tacrolimus in the first year after renal transplantation. European Tacrolimus Multicentre Renal Study Group. Transplant Proc 1998; 30: 1261-3.
    • (1998) Transplant Proc , vol.30 , pp. 1261-3
    • Undre, N.A.1    Schafer, A.2
  • 25
    • 0031832692 scopus 로고    scopus 로고
    • Effect of breakfast on the oral bioavailability of tacrolimus and changes in pharmacokinetics at different times posttransplant in renal transplant recipients
    • Christiaans M, van Duijnhoven E, Beysens T, Undre N, Schafer A, van Hooff J. Effect of breakfast on the oral bioavailability of tacrolimus and changes in pharmacokinetics at different times posttransplant in renal transplant recipients. Transplant Proc 1998; 30: 1271-3.
    • (1998) Transplant Proc , vol.30 , pp. 1271-3
    • Christiaans, M.1    van Duijnhoven, E.2    Beysens, T.3    Undre, N.4    Schafer, A.5    van Hooff, J.6
  • 28
    • 0032570530 scopus 로고    scopus 로고
    • Racial differences in renal transplantation after immunosuppression with tacrolimus versus cyclosporine. FK506 Kidney Transplant Study Group
    • Neylan JF. Racial differences in renal transplantation after immunosuppression with tacrolimus versus cyclosporine. FK506 Kidney Transplant Study Group. Transplantation 1998; 65: 515-23.
    • (1998) Transplantation , vol.65 , pp. 515-23
    • Neylan, J.F.1
  • 29
    • 0031859573 scopus 로고    scopus 로고
    • Effect of race and immunosuppression in renal transplantation: three-year survival results from a US multicenter, randomized trial. FK506 Kidney Transplant Study Group
    • Neylan JF. Effect of race and immunosuppression in renal transplantation: three-year survival results from a US multicenter, randomized trial. FK506 Kidney Transplant Study Group. Transplant Proc 1998; 30: 1355-8.
    • (1998) Transplant Proc , vol.30 , pp. 1355-8
    • Neylan, J.F.1
  • 30
    • 0035085706 scopus 로고    scopus 로고
    • Choosing the right dose of new immunossuppressive drugs for new populations: importance of pharmacokinetic studies
    • Felipe CR, Garcia C, Moreira S, Olsen N, Silva HT, Pestana OM. Choosing the right dose of new immunossuppressive drugs for new populations: importance of pharmacokinetic studies. Transplant Proc 2001; 33: 1095-6.
    • (2001) Transplant Proc , vol.33 , pp. 1095-6
    • Felipe, C.R.1    Garcia, C.2    Moreira, S.3    Olsen, N.4    Silva, H.T.5    Pestana, O.M.6
  • 32
    • 0035136948 scopus 로고    scopus 로고
    • Effect of low- and high-fat meals on tacrolimus absorption following 5 mg single oral doses to healthy human subjects
    • Bekersky I, Dressler D, Mekki QA. Effect of low- and high-fat meals on tacrolimus absorption following 5 mg single oral doses to healthy human subjects. J Clin Pharmacol 2001; 41: 176-82.
    • (2001) J Clin Pharmacol , vol.41 , pp. 176-82
    • Bekersky, I.1    Dressler, D.2    Mekki, Q.A.3
  • 33
    • 0035120428 scopus 로고    scopus 로고
    • Effect of time of meal consumption on bioavailability of a single oral 5 mg tacrolimus dose
    • Bekersky I, Dressler D, Mekki Q. Effect of time of meal consumption on bioavailability of a single oral 5 mg tacrolimus dose. J Clin Pharmacol 2001; 41: 289-97.
    • (2001) J Clin Pharmacol , vol.41 , pp. 289-97
    • Bekersky, I.1    Dressler, D.2    Mekki, Q.3
  • 34
    • 0033985558 scopus 로고    scopus 로고
    • Increased tacrolimus levels in a pediatric renal transplant patient attributed to chronic diarrhea
    • Eades SK, Boineau FG, Christensen ML. Increased tacrolimus levels in a pediatric renal transplant patient attributed to chronic diarrhea. Pediatr Transplant 2000; 4: 63-6.
    • (2000) Pediatr Transplant , vol.4 , pp. 63-6
    • Eades, S.K.1    Boineau, F.G.2    Christensen, M.L.3
  • 35
    • 0029856037 scopus 로고    scopus 로고
    • Apparently increased trough levels of tacrolimus caused by acute infantile diarrhea in two infants with biliary atresia after liver transplantation
    • Matsui A, Arakawa Y, Momoya T, Sasaki N, Kawasaki S, Tanaka K. Apparently increased trough levels of tacrolimus caused by acute infantile diarrhea in two infants with biliary atresia after liver transplantation. Acta Paediatr Jpn 1996; 38: 699-701.
    • (1996) Acta Paediatr Jpn , vol.38 , pp. 699-701
    • Matsui, A.1    Arakawa, Y.2    Momoya, T.3    Sasaki, N.4    Kawasaki, S.5    Tanaka, K.6
  • 36
    • 0031804206 scopus 로고    scopus 로고
    • Tacrolimus dosing requirements in diabetic and nondiabetic patients calculated from pretransplantation data
    • van Duijnhoven E, Christiaans M, Schafer A, Undre N, van Hooff J. Tacrolimus dosing requirements in diabetic and nondiabetic patients calculated from pretransplantation data. Transplant Proc 1998; 30: 1266-7.
    • (1998) Transplant Proc , vol.30 , pp. 1266-7
    • van Duijnhoven, E.1    Christiaans, M.2    Schafer, A.3    Undre, N.4    van Hooff, J.5
  • 37
    • 0031803468 scopus 로고    scopus 로고
    • Clinical use and bioavailability of tacrolimus in heart-lung and double lung transplant recipients with cystic fibrosis
    • Walker S, Habib S, Rose M, Yacoub M, Banner N. Clinical use and bioavailability of tacrolimus in heart-lung and double lung transplant recipients with cystic fibrosis. Transplant Proc 1998; 30: 1519-20.
    • (1998) Transplant Proc , vol.30 , pp. 1519-20
    • Walker, S.1    Habib, S.2    Rose, M.3    Yacoub, M.4    Banner, N.5
  • 41
    • 0034794358 scopus 로고    scopus 로고
    • Effective oral administration of tacrolimus in renal transplant recipients
    • Kimikawa M, Kamoya K, Toma H, Teraoka S. Effective oral administration of tacrolimus in renal transplant recipients. Clin Transplant 2001; 15: 324-9.
    • (2001) Clin Transplant , vol.15 , pp. 324-9
    • Kimikawa, M.1    Kamoya, K.2    Toma, H.3    Teraoka, S.4
  • 43
    • 0035993643 scopus 로고    scopus 로고
    • Effect of bile flow on the absorption of tacrolimus in liver allograft transplantation
    • Bottiger Y, Undre NA, Sawe J, Stevenson PJ, Ericzon BG. Effect of bile flow on the absorption of tacrolimus in liver allograft transplantation. Transplant Proc 2002; 34: 1544-5.
    • (2002) Transplant Proc , vol.34 , pp. 1544-5
    • Bottiger, Y.1    Undre, N.A.2    Sawe, J.3    Stevenson, P.J.4    Ericzon, B.G.5
  • 44
    • 0034031378 scopus 로고    scopus 로고
    • Abbreviated tacrolimus area-under-the-curve monitoring for renal transplant recipients
    • Wong KM, Shek CC, Chau KF, Li CS. Abbreviated tacrolimus area-under-the-curve monitoring for renal transplant recipients. Am J Kidney Dis 2000; 35: 660-6.
    • (2000) Am J Kidney Dis , vol.35 , pp. 660-6
    • Wong, K.M.1    Shek, C.C.2    Chau, K.F.3    Li, C.S.4
  • 48
    • 0038500544 scopus 로고    scopus 로고
    • C2 (2-h) levels are not superior to trough levels as estimates of the area under the curve in tacrolimus-treated renal-transplant patients
    • Jorgensen K, Povlsen J, Madsen S, Madsen M, Hansen H, Pedersen A, Heinsvig EM, Poulsen J. C2 (2-h) levels are not superior to trough levels as estimates of the area under the curve in tacrolimus-treated renal-transplant patients. Nephrol Dial Transplant 2002; 17: 1487-90.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 1487-90
    • Jorgensen, K.1    Povlsen, J.2    Madsen, S.3    Madsen, M.4    Hansen, H.5    Pedersen, A.6    Heinsvig, E.M.7    Poulsen, J.8
  • 50
    • 23244454653 scopus 로고    scopus 로고
    • Evaluation of a limited sampling strategy to estimate area under the curve of tacrolimus in adult renal transplant patients
    • Armendariz Y, Pou L, Cantarell C, Lopez R, Perello M, Capdevila L. Evaluation of a limited sampling strategy to estimate area under the curve of tacrolimus in adult renal transplant patients. Ther Drug Monit 2005; 27: 431-4.
    • (2005) Ther Drug Monit , vol.27 , pp. 431-4
    • Armendariz, Y.1    Pou, L.2    Cantarell, C.3    Lopez, R.4    Perello, M.5    Capdevila, L.6
  • 51
    • 0029805879 scopus 로고    scopus 로고
    • An open-label, concentration-ranging trial of FK506 in primary kidney transplantation: a report of the United States Multicenter FK506 Kidney Transplant Group
    • Laskow DA, Vincenti F, Neylan JF, Mendez R, Matas AJ. An open-label, concentration-ranging trial of FK506 in primary kidney transplantation: a report of the United States Multicenter FK506 Kidney Transplant Group. Transplantation 1996; 62: 900-5.
    • (1996) Transplantation , vol.62 , pp. 900-5
    • Laskow, D.A.1    Vincenti, F.2    Neylan, J.F.3    Mendez, R.4    Matas, A.J.5
  • 52
    • 33748124928 scopus 로고    scopus 로고
    • Beyond cyclosporine: a systematic review of limited sampling strategies for other immunosuppressants
    • Ting LS, Villeneuve E, Ensom MH. Beyond cyclosporine: a systematic review of limited sampling strategies for other immunosuppressants. Ther Drug Monit 2006; 28: 419-30.
    • (2006) Ther Drug Monit , vol.28 , pp. 419-30
    • Ting, L.S.1    Villeneuve, E.2    Ensom, M.H.3
  • 55
    • 77955706860 scopus 로고    scopus 로고
    • PI P. A high-throughput HPLC-MS/MS method for tacrolimus measurement (abstract)
    • Taylor PJ, Brown SR, Cooper DP, Lynch SV. PI P. A high-throughput HPLC-MS/MS method for tacrolimus measurement (abstract). Ther Drug Monit 2005; 27: 256.
    • (2005) Ther Drug Monit , vol.27 , pp. 256
    • Taylor, P.J.1    Brown, S.R.2    Cooper, D.P.3    Lynch, S.V.4
  • 56
    • 0036727094 scopus 로고    scopus 로고
    • Evaluation of a rapid micro-scale assay for tacrolimus by liquid chromatography-tandem mass spectrometry
    • Keevil BG, McCann SJ, Cooper DP, Morris MR. Evaluation of a rapid micro-scale assay for tacrolimus by liquid chromatography-tandem mass spectrometry. Ann Clin Biochem 2002; 39: 487-92.
    • (2002) Ann Clin Biochem , vol.39 , pp. 487-92
    • Keevil, B.G.1    McCann, S.J.2    Cooper, D.P.3    Morris, M.R.4
  • 57
    • 38549091212 scopus 로고    scopus 로고
    • Limited sampling strategy for simultaneous estimation of the area under the concentration-time curve of tacrolimus and mycophenolic acid in adult renal transplant recipients
    • Miura M, Satoh S, Niioka T, Kagaya H, Saito M, Hayakari M, Habuchi T, Suzuki T. Limited sampling strategy for simultaneous estimation of the area under the concentration-time curve of tacrolimus and mycophenolic acid in adult renal transplant recipients. Ther Drug Monit 2008; 30: 52-9.
    • (2008) Ther Drug Monit , vol.30 , pp. 52-9
    • Miura, M.1    Satoh, S.2    Niioka, T.3    Kagaya, H.4    Saito, M.5    Hayakari, M.6    Habuchi, T.7    Suzuki, T.8
  • 58
    • 4344561078 scopus 로고    scopus 로고
    • Time-related clinical determinants of long-term tacrolimus pharmacokinetics in combination therapy with mycophenolic acid and corticosteroids: a prospective study in one hundred de novo renal transplant recipients
    • Kuypers DR, Claes K, Evenepoel P, Maes B, Coosemans W, Pirenne J, Vanrenterghem Y. Time-related clinical determinants of long-term tacrolimus pharmacokinetics in combination therapy with mycophenolic acid and corticosteroids: a prospective study in one hundred de novo renal transplant recipients. Clin Pharmacokinet 2004; 43: 741-62.
    • (2004) Clin Pharmacokinet , vol.43 , pp. 741-62
    • Kuypers, D.R.1    Claes, K.2    Evenepoel, P.3    Maes, B.4    Coosemans, W.5    Pirenne, J.6    Vanrenterghem, Y.7
  • 59
    • 0036460331 scopus 로고    scopus 로고
    • Comparison of two population pharmacokinetic programs, NONMEM and P-PHARM, for tacrolimus
    • Staatz CE, Tett SE. Comparison of two population pharmacokinetic programs, NONMEM and P-PHARM, for tacrolimus. Eur J Clin Pharmacol 2002; 58: 597-605.
    • (2002) Eur J Clin Pharmacol , vol.58 , pp. 597-605
    • Staatz, C.E.1    Tett, S.E.2
  • 60
    • 36849058757 scopus 로고    scopus 로고
    • Population pharmacokinetics and bioavailability of tacrolimus in kidney transplant patients
    • Antignac M, Barrou B, Farinotti R, Lechat P, Urien S. Population pharmacokinetics and bioavailability of tacrolimus in kidney transplant patients. Br J Clin Pharmacol 2007; 64: 750-7.
    • (2007) Br J Clin Pharmacol , vol.64 , pp. 750-7
    • Antignac, M.1    Barrou, B.2    Farinotti, R.3    Lechat, P.4    Urien, S.5
  • 62
    • 73849134895 scopus 로고    scopus 로고
    • Time of drug administration, CYP3A5 and ABCB1 genotypes, and analytical method influence tacrolimus pharmacokinetics: a population pharmacokinetic study
    • Musuamba FT, Mourad M, Haufroid V, Delattre IK, Verbeeck RK, Wallemacq P. Time of drug administration, CYP3A5 and ABCB1 genotypes, and analytical method influence tacrolimus pharmacokinetics: a population pharmacokinetic study. Ther Drug Monit 2009; 31: 734-42.
    • (2009) Ther Drug Monit , vol.31 , pp. 734-42
    • Musuamba, F.T.1    Mourad, M.2    Haufroid, V.3    Delattre, I.K.4    Verbeeck, R.K.5    Wallemacq, P.6
  • 64
    • 78650965842 scopus 로고    scopus 로고
    • Limoges University Hospital Laboratory of Pharmacology. Target Concentration Intervention Software (TCIworks). Available at (last accessed 20 May 2010).
    • Limoges University Hospital Laboratory of Pharmacology. Target Concentration Intervention Software (TCIworks). Available at (last accessed 20 May 2010).
  • 65
    • 78650996157 scopus 로고    scopus 로고
    • Limoges University Hospital Laboratory of Pharmacology. ImmunoSuppressants Bayesian dose Adjustment (ISBA). Available at, last accessed 20 May 2010).
    • Limoges University Hospital Laboratory of Pharmacology. ImmunoSuppressants Bayesian dose Adjustment (ISBA). Available at (last accessed 20 May 2010).
  • 66
    • 0019604592 scopus 로고
    • Some suggestions for measuring predictive performance
    • Sheiner LB, Beal SL. Some suggestions for measuring predictive performance. J Pharmacokinet Biopharm 1981; 9: 503-12.
    • (1981) J Pharmacokinet Biopharm , vol.9 , pp. 503-12
    • Sheiner, L.B.1    Beal, S.L.2
  • 67
    • 33646760954 scopus 로고    scopus 로고
    • Kidney function estimating equations: where do we stand?
    • Coresh J, Stevens LA. Kidney function estimating equations: where do we stand? Curr Opin Nephrol Hypertens 2006; 15: 276-84.
    • (2006) Curr Opin Nephrol Hypertens , vol.15 , pp. 276-84
    • Coresh, J.1    Stevens, L.A.2
  • 69
    • 0038684549 scopus 로고    scopus 로고
    • Pharmacokinetics of tacrolimus-based combination therapies
    • Undre NA. Pharmacokinetics of tacrolimus-based combination therapies. Nephrol Dial Transplant 2003; 18: (Suppl. 1): i12-5.
    • (2003) Nephrol Dial Transplant , vol.18 , Issue.1 SUPPL.
    • Undre, N.A.1


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