-
1
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-kB pathways by diverse genetic abnormalities in multiple myeloma
-
Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F et al. (2007). Frequent engagement of the classical and alternative NF-kB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 12: 115-130.
-
(2007)
Cancer Cell
, vol.12
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
Bellamy, W.4
Gabrea, A.5
Zhan, F.6
-
2
-
-
33750432183
-
NF-kB and IkB kinase pathways in oncogenic initiation and progression
-
Basseres DS, Baldwin AS. (2006). NF-kB and IkB kinase pathways in oncogenic initiation and progression. Oncogene 25: 6817-6830.
-
(2006)
Oncogene
, vol.25
, pp. 6817-6830
-
-
Basseres, D.S.1
Baldwin, A.S.2
-
3
-
-
4444358394
-
Cytosolic, nuclear and nucleolar localization signals determine subcellular distribution and activity of the NF-kB inducing kinase NIK
-
Birbach A, Bailey ST, Ghosh S, Schmid JA. (2004). Cytosolic, nuclear and nucleolar localization signals determine subcellular distribution and activity of the NF-kB inducing kinase NIK. J Cell Sci 117: 3615-3624.
-
(2004)
J Cell Sci
, vol.117
, pp. 3615-3624
-
-
Birbach, A.1
Bailey, S.T.2
Ghosh, S.3
Schmid, J.A.4
-
4
-
-
26844576749
-
Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene
-
Borrello MG, Alberti L, Fischer A, Degl'innocenti D, Ferrario C, Gariboldi M et al. (2005). Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene. Proc Natl Acad Sci USA 102: 14825-14830.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14825-14830
-
-
Borrello, M.G.1
Alberti, L.2
Fischer, A.3
Degl'Innocenti, D.4
Ferrario, C.5
Gariboldi, M.6
-
5
-
-
0034213657
-
RET receptor expression in thyroid follicular epithelial cell-derived tumors
-
Bunone G, Uggeri M, Mondellini P, Pierotti MA, Bongarzone I. (2000). RET receptor expression in thyroid follicular epithelial cell-derived tumors. Cancer Res 60: 2845-2849.
-
(2000)
Cancer Res
, vol.60
, pp. 2845-2849
-
-
Bunone, G.1
Uggeri, M.2
Mondellini, P.3
Pierotti, M.A.4
Bongarzone, I.5
-
6
-
-
33847072340
-
RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis
-
Ciampi R, Nikiforov YE. (2007). RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis. Endocrinology 148: 936-941.
-
(2007)
Endocrinology
, vol.148
, pp. 936-941
-
-
Ciampi, R.1
Nikiforov, Y.E.2
-
7
-
-
18644380147
-
The lymphotoxin-b receptor induces different patterns of gene expression via two NF-kB pathways
-
Dejardin E, Droin NM, Delhase M, Haas E, Cao Y, Makris C et al. (2002). The lymphotoxin-b receptor induces different patterns of gene expression via two NF-kB pathways. Immunity 17: 525-535.
-
(2002)
Immunity
, vol.17
, pp. 525-535
-
-
Dejardin, E.1
Droin, N.M.2
Delhase, M.3
Haas, E.4
Cao, Y.5
Makris, C.6
-
8
-
-
0037931474
-
RelB/p50 dimers are differentially regulated by tumor necrosis factor - A and lymphotoxin-b receptor activation: Critical roles for p100
-
Derudder E, Dejardin E, Pritchard LL, Green DR, Korner M, Baud V. (2003). RelB/p50 dimers are differentially regulated by tumor necrosis factor-a and lymphotoxin-b receptor activation: critical roles for p100. J Biol Chem 278: 23278-23284.
-
(2003)
J Biol Chem
, vol.278
, pp. 23278-23284
-
-
Derudder, E.1
Dejardin, E.2
Pritchard, L.L.3
Green, D.R.4
Korner, M.5
Baud, V.6
-
9
-
-
33751320904
-
Oncogenic inflammation and autoimmune disease
-
Eisenlohr LC, Rothstein JL. (2006). Oncogenic inflammation and autoimmune disease. Autoimmun Rev 6: 107-114.
-
(2006)
Autoimmun Rev
, vol.6
, pp. 107-114
-
-
Eisenlohr, L.C.1
Rothstein, J.L.2
-
10
-
-
33750446341
-
Inhibitors of NF-kB signaling: 785 and counting
-
Gilmore TD, Herscovitch M. (2006). Inhibitors of NF-kB signaling: 785 and counting. Oncogene 25: 6887-6899.
-
(2006)
Oncogene
, vol.25
, pp. 6887-6899
-
-
Gilmore, T.D.1
Herscovitch, M.2
-
11
-
-
0034648718
-
Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor
-
Hayashi H, Ichihara M, Iwashita T, Murakami H, Shimono Y, Kawai K et al. (2000). Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor. Oncogene 19: 4469-4475.
-
(2000)
Oncogene
, vol.19
, pp. 4469-4475
-
-
Hayashi, H.1
Ichihara, M.2
Iwashita, T.3
Murakami, H.4
Shimono, Y.5
Kawai, K.6
-
12
-
-
38849199203
-
Shared principles in NF-kB signaling
-
Hayden MS, Ghosh S. (2008). Shared principles in NF-kB signaling. Cell 132: 344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
13
-
-
33947506490
-
Specificity of TRAF3 in its negative regulation of the noncanonical NF-kB pathway
-
He JQ, Saha SK, Kang JR, Zarnegar B, Cheng G. (2007). Specificity of TRAF3 in its negative regulation of the noncanonical NF-kB pathway. J Biol Chem 282: 3688-3694.
-
(2007)
J Biol Chem
, vol.282
, pp. 3688-3694
-
-
He, J.Q.1
Saha, S.K.2
Kang, J.R.3
Zarnegar, B.4
Cheng, G.5
-
14
-
-
33745298519
-
NF-kB in cancer development and progression
-
Karin M. (2006). NF-kB in cancer development and progression. Nature 441: 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
15
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-kB pathway in multiple myeloma
-
Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ et al.(2007). Promiscuous mutations activate the noncanonical NF-kB pathway in multiple myeloma. Cancer Cell 12: 131-144.
-
(2007)
Cancer Cell
, vol.12
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
Schop, R.4
Baker, A.5
Chng, W.J.6
-
16
-
-
58549104540
-
Compensatory IKKa activation of classical NF-kB signaling during IKKb inhibition identified by an RNA interference sensitization screen
-
Lam LT, Davis RE, Ngo VN, Lenz G, Wright G, Xu W et al. (2008). Compensatory IKKa activation of classical NF-kB signaling during IKKb inhibition identified by an RNA interference sensitization screen. Proc Natl Acad Sci USA 105: 20798-20803.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20798-20803
-
-
Lam, L.T.1
Davis, R.E.2
Ngo, V.N.3
Lenz, G.4
Wright, G.5
Xu, W.6
-
17
-
-
60549111185
-
XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway
-
Lodyga M, De Falco V, Bai XH, Kapus A, Melillo RM, Santoro M et al. (2009). XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway. Oncogene 28: 937-949.
-
(2009)
Oncogene
, vol.28
, pp. 937-949
-
-
Lodyga, M.1
De Falco, V.2
Bai, X.H.3
Kapus, A.4
Melillo, R.M.5
Santoro, M.6
-
18
-
-
0035354187
-
NF-kB is constitutively active in C-cell carcinoma and required for RET-induced transformation
-
Ludwig L, Kessler H, Wagner M, Hoang-Vu C, Dralle H, Adler G et al. (2001). NF-kB is constitutively active in C-cell carcinoma and required for RET-induced transformation. Cancer Res 61: 4526-4535.
-
(2001)
Cancer Res
, vol.61
, pp. 4526-4535
-
-
Ludwig, L.1
Kessler, H.2
Wagner, M.3
Hoang-Vu, C.4
Dralle, H.5
Adler, G.6
-
19
-
-
48149114957
-
Lymphotoxin-a1b2 and LIGHT induce classical and noncanonical NF-kB-dependent proinflammatory gene expression in vascular endothelial cells
-
Madge LA, Kluger MS, Orange JS, May MJ. (2008). Lymphotoxin-a1b2 and LIGHT induce classical and noncanonical NF-kB-dependent proinflammatory gene expression in vascular endothelial cells. J Immunol 180: 3467-3477.
-
(2008)
J Immunol
, vol.180
, pp. 3467-3477
-
-
Madge, L.A.1
Kluger, M.S.2
Orange, J.S.3
May, M.J.4
-
20
-
-
0034284715
-
Selective inhibition of NF-kB activation by a peptide that blocks the interaction of NEMO with the IkB kinase complex
-
May MJ, D'Acquisto F, Madge LA, Glockner J, Pober JS, Ghosh S. (2000). Selective inhibition of NF-kB activation by a peptide that blocks the interaction of NEMO with the IkB kinase complex. Science 289: 1550-1554.
-
(2000)
Science
, vol.289
, pp. 1550-1554
-
-
May, M.J.1
D'Acquisto, F.2
Madge, L.A.3
Glockner, J.4
Pober, J.S.5
Ghosh, S.6
-
21
-
-
17744390860
-
The RFG oligomerization domain mediates kinase activation and re-localization of the RET/PTC3 oncoprotein to the plasma membrane
-
Monaco C, Visconti R, Barone MV, Pierantoni GM, Berlingieri MT, De Lorenzo C et al. (2001). The RFG oligomerization domain mediates kinase activation and re-localization of the RET/PTC3 oncoprotein to the plasma membrane. Oncogene 20: 599-608.
-
(2001)
Oncogene
, vol.20
, pp. 599-608
-
-
Monaco, C.1
Visconti, R.2
Barone, M.V.3
Pierantoni, G.M.4
Berlingieri, M.T.5
De Lorenzo, C.6
-
22
-
-
77950198905
-
The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: Clinical and molecular studies
-
Muzza M, Degl'innocenti D, Colombo C, Perrino M, Ravasi E, Rossi S et al. (2009). The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: clinical and molecular studies. Clin Endocrinol (Oxf) 72: 702-708.
-
(2009)
Clin Endocrinol (Oxf)
, vol.72
, pp. 702-708
-
-
Muzza, M.1
Degl'Innocenti, D.2
Colombo, C.3
Perrino, M.4
Ravasi, E.5
Rossi, S.6
-
23
-
-
62349140432
-
Loss of Rap1GAP in papillary thyroid cancer
-
Nellore A, Paziana K, Ma C, Tsygankova OM, Wang Y, Puttaswamy K et al. (2009). Loss of Rap1GAP in papillary thyroid cancer. J Clin Endocrinol Metab 94: 1026-1032.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1026-1032
-
-
Nellore, A.1
Paziana, K.2
Ma, C.3
Tsygankova, O.M.4
Wang, Y.5
Puttaswamy, K.6
-
24
-
-
20044368066
-
RET/PTC fusion gene rearrangements in Japanese thyroid carcinomas
-
Nibu K, Otsuki N, Nakao K, Sugasawa M, Rothstein JL. (2005). RET/PTC fusion gene rearrangements in Japanese thyroid carcinomas. Eur Arch Otorhinolaryngol 262: 368-373.
-
(2005)
Eur Arch Otorhinolaryngol
, vol.262
, pp. 368-373
-
-
Nibu, K.1
Otsuki, N.2
Nakao, K.3
Sugasawa, M.4
Rothstein, J.L.5
-
25
-
-
68949097479
-
NIK is involved in constitutive activation of the alternative NF-kB pathway and proliferation of pancreatic cancer cells
-
Nishina T, Yamaguchi N, Gohda J, Semba K, Inoue J. (2009). NIK is involved in constitutive activation of the alternative NF-kB pathway and proliferation of pancreatic cancer cells. Biochem Biophys Res Commun 388: 96-101.
-
(2009)
Biochem Biophys Res Commun
, vol.388
, pp. 96-101
-
-
Nishina, T.1
Yamaguchi, N.2
Gohda, J.3
Semba, K.4
Inoue, J.5
-
27
-
-
19944426112
-
Oncogenic and anti-apoptotic activity of NF-kB in human thyroid carcinomas
-
Pacifico F, Mauro C, Barone C, Crescenzi E, Mellone S, Monaco M et al. (2004). Oncogenic and anti-apoptotic activity of NF-kB in human thyroid carcinomas. J Biol Chem 279: 54610-54619.
-
(2004)
J Biol Chem
, vol.279
, pp. 54610-54619
-
-
Pacifico, F.1
Mauro, C.2
Barone, C.3
Crescenzi, E.4
Mellone, S.5
Monaco, M.6
-
28
-
-
66949119313
-
Oncoprotein signaling mediates tumor-specific inflammation and enhances tumor progression
-
Pufnock JS, Rothstein JL. (2009). Oncoprotein signaling mediates tumor-specific inflammation and enhances tumor progression. J Immunol 182: 5498-5506.
-
(2009)
J Immunol
, vol.182
, pp. 5498-5506
-
-
Pufnock, J.S.1
Rothstein, J.L.2
-
29
-
-
77953824286
-
Negative feedback in noncanonical NF-kB signaling modulates NIK stability through IKKa-mediated phosphorylation
-
Razani B, Zarnegar B, Ytterberg AJ, Shiba T, Dempsey PW, Ware CF et al. (2010). Negative feedback in noncanonical NF-kB signaling modulates NIK stability through IKKa-mediated phosphorylation. Sci Signal 3: ra41.
-
(2010)
Sci Signal
, vol.3
-
-
Razani, B.1
Zarnegar, B.2
Ytterberg, A.J.3
Shiba, T.4
Dempsey, P.W.5
Ware, C.F.6
-
30
-
-
33744962523
-
RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: Follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma
-
Rhoden KJ, Unger K, Salvatore G, Yilmaz Y, Vovk V, Chiappetta G et al. (2006). RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma. J Clin Endocrinol Metab 91: 2414-2423.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2414-2423
-
-
Rhoden, K.J.1
Unger, K.2
Salvatore, G.3
Yilmaz, Y.4
Vovk, V.5
Chiappetta, G.6
-
31
-
-
0043170839
-
Tyrosine kinase oncoprotein, RET/PTC3, induces the secretion of myeloid growth and chemotactic factors
-
Russell JP, Shinohara S, Melillo RM, Castellone MD, Santoro M, Rothstein JL. (2003). Tyrosine kinase oncoprotein, RET/PTC3, induces the secretion of myeloid growth and chemotactic factors. Oncogene 22: 4569-4577.
-
(2003)
Oncogene
, vol.22
, pp. 4569-4577
-
-
Russell, J.P.1
Shinohara, S.2
Melillo, R.M.3
Castellone, M.D.4
Santoro, M.5
Rothstein, J.L.6
-
32
-
-
0027548295
-
The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line
-
Santoro M, Melillo RM, Grieco M, Berlingieri MT, Vecchio G, Fusco A. (1993). The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line. Cell Growth Differ 4: 77-84.
-
(1993)
Cell Growth Differ
, vol.4
, pp. 77-84
-
-
Santoro, M.1
Melillo, R.M.2
Grieco, M.3
Berlingieri, M.T.4
Vecchio, G.5
Fusco, A.6
-
33
-
-
17944378526
-
Activation by IKKa of a second, evolutionary conserved, NF-kB signaling pathway
-
Senftleben U, Cao Y, Xiao G, Greten FR, Krahn G, Bonizzi G et al. (2001). Activation by IKKa of a second, evolutionary conserved, NF-kB signaling pathway. Science 293: 1495-1499.
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
Greten, F.R.4
Krahn, G.5
Bonizzi, G.6
-
34
-
-
0033796849
-
RET/PTC-1 activation in Hashimoto thyroiditis
-
Sheils OM, O'Eary JJ, Uhlmann V, Lattich K, Sweeney EC. (2000). RET/PTC-1 activation in Hashimoto thyroiditis. Int J Surg Pathol 8: 185-189.
-
(2000)
Int J Surg Pathol
, vol.8
, pp. 185-189
-
-
Sheils, O.M.1
O'Eary, J.J.2
Uhlmann, V.3
Lattich, K.4
Sweeney, E.C.5
-
35
-
-
34247874508
-
Interleukin-1-induced NF-kB activation is NEMO-dependent but does not require IKKb
-
Solt LA, Madge LA, Orange JS, May MJ. (2007). Interleukin-1-induced NF-kB activation is NEMO-dependent but does not require IKKb. J Biol Chem 282: 8724-8733.
-
(2007)
J Biol Chem
, vol.282
, pp. 8724-8733
-
-
Solt, L.A.1
Madge, L.A.2
Orange, J.S.3
May, M.J.4
-
36
-
-
56349164232
-
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kB signaling
-
Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, Wang H et al. (2008). Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kB signaling. Nat Immunol 9: 1364-1370.
-
(2008)
Nat Immunol
, vol.9
, pp. 1364-1370
-
-
Vallabhapurapu, S.1
Matsuzawa, A.2
Zhang, W.3
Tseng, P.H.4
Keats, J.J.5
Wang, H.6
-
37
-
-
34047158654
-
Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis
-
Veiga-Fernandes H, Coles MC, Foster KE, Patel A, Williams A, Natarajan D et al. (2007). Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis. Nature 446: 547-551.
-
(2007)
Nature
, vol.446
, pp. 547-551
-
-
Veiga-Fernandes, H.1
Coles, M.C.2
Foster, K.E.3
Patel, A.4
Williams, A.5
Natarajan, D.6
-
38
-
-
0030666532
-
Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NF-kB p65 protein expression
-
Visconti R, Cerutti J, Battista S, Fedele M, Trapasso F, Zeki K et al. (1997). Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NF-kB p65 protein expression. Oncogene 15: 1987-1994.
-
(1997)
Oncogene
, vol.15
, pp. 1987-1994
-
-
Visconti, R.1
Cerutti, J.2
Battista, S.3
Fedele, M.4
Trapasso, F.5
Zeki, K.6
-
39
-
-
73149115248
-
Targeting the RET pathway in thyroid cancer
-
Wells Jr SA, Santoro M. (2009). Targeting the RET pathway in thyroid cancer. Clin Cancer Res 15: 7119-7123.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7119-7123
-
-
Wells Jr., S.A.1
Santoro, M.2
-
40
-
-
85046913982
-
Constitutive non-canonical NF-kB signaling in pancreatic cancer cells
-
Wharry CE, Haines KM, Carroll RG, May MJ. (2009). Constitutive non-canonical NF-kB signaling in pancreatic cancer cells. Cancer Biol Ther 8: 1567-1576.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1567-1576
-
-
Wharry, C.E.1
Haines, K.M.2
Carroll, R.G.3
May, M.J.4
-
41
-
-
0031031158
-
Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis
-
Wirtschafter A, Schmidt R, Rosen D, Kundu N, Santoro M, Fusco A et al. (1997). Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis. Laryngoscope 107: 95-100.
-
(1997)
Laryngoscope
, vol.107
, pp. 95-100
-
-
Wirtschafter, A.1
Schmidt, R.2
Rosen, D.3
Kundu, N.4
Santoro, M.5
Fusco, A.6
-
42
-
-
0034745420
-
NF-kB-inducing kinase regulates the processing of NF-kB2 p100
-
Xiao G, Harhaj EW, Sun SC. (2001). NF-kB-inducing kinase regulates the processing of NF-kB2 p100. Mol Cell 7: 401-409.
-
(2001)
Mol Cell
, vol.7
, pp. 401-409
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.C.3
-
43
-
-
42149110830
-
Control of canonical NF-kB activation through the NIK-IKK complex pathway
-
Zarnegar B, Yamazaki S, He JQ, Cheng G. (2008). Control of canonical NF-kB activation through the NIK-IKK complex pathway. Proc Natl Acad Sci USA 105: 3503-3508.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3503-3508
-
-
Zarnegar, B.1
Yamazaki, S.2
He, J.Q.3
Cheng, G.4
|