The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: Clinical and molecular studies

Clinical Endocrinology

Volumn 72, Issue 5, 2010, Pages 702-708

  Muzza, Marina ^a   Degl'Innocenti, Debora ^b   Colombo, Carla ^a   Perrino, Michela ^a   Ravasi, Elena ^b   Rossi, Stefania ^a   Cirello, Valentina ^a   Beck Peccoz, Paolo ^a   Borrello, Maria Grazia ^b   Fugazzola, Laura ^a,c  

^a UNIVERSITY OF MILAN   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; INTERLEUKIN 8; L SELECTIN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; PROTEIN PATCHED 1; PROTEIN RET;

ADOLESCENT; ADULT; AGED; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CANCER STAGING; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENE MUTATION; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; THYROID PAPILLARY CARCINOMA; THYROIDITIS;

ADOLESCENT; ADULT; AGED; AUTOIMMUNITY; CARCINOMA, PAPILLARY; CHEMOKINE CCL20; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; INFLAMMATION; INTERLEUKIN-8; MALE; MIDDLE AGED; MUTATION; ONCOGENE PROTEINS, FUSION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS B-RAF; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYROID NEOPLASMS; THYROIDITIS; YOUNG ADULT;

EID: 77950198905     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2009.03699.x     Document Type: Article

References (30)

1. Mantovani, A., Allavena, P., Sica, A. et al. (2008) Cancer-related inflammation. Nature, 54, 436 444.
2. Coussens, L.M. Werb, Z. (2002) Inflammation and cancer. Nature, 420, 860 867.
3. Borrello, M.G., Alberti, L., Fischer, A. et al. (2005) Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene. Proceedings of the National Academy of Sciences of the United States of America, 102, 14825 14830.
4. Melillo, R.M., Castellone, M.D., Guarino, V. et al. (2005) The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells. Journal of Clinical Investigation, 115, 1068 1081.
5. Borrello, M.G., Degl'Innocenti, D. Pierotti, M. (2008) Inflammation and cancer: the oncogene-driven connection. Cancer Letters, 267, 262 270.
6. Russel, J.P., Shinoara, S., Melillo, R.M. et al. (2003) Tyrosine kinase oncoprotein, RET/PTC3, indices the secretion of myeloid growth and chemotactic factors. Oncogene, 22, 4569 4577.
7. Puxeddu, E., Knauf, J.A., Sartor, M.A. et al. (2005) RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activation of genes involved in regulation of the immune response. Endocrine Related Cancer, 12, 319 334.
8. Loh, K.C., Greenspan, F.S., Dong, F. et al. (1999) Influence of lymphocytic thyroiditis on the prognostic outcome of patients with papillary thyroid carcinoma. Journal of Clinical Endocrinology and Metabolism, 84, 458 462.
9. Ugolini, C., Basolo, F., Proietti, A. et al. (2007) Lymphocyte and immature dendritic cell infiltrates in differentiated, poorly differentiated, and undifferentiated thyroid carcinoma. Thyroid, 17, 389 393.
10. Ozaki, O., Ito, K., Kobayashi, K. et al. (1990) Thyroid carcinoma in Graves' disease. World Journal of Surgery, 14, 437 440.
11. Pellegriti, G., Belfiore, A., Giuffrida, D. et al. (1998) Outcome of differentiated thyroid cancer in Graves' patients. Journal of Clinical Endocrinology and Metabolism, 83, 2805 2809.
12. Matsubasyashi, S., Kawai, K., Matsumoto, Y. et al. (1995) The correlation between papillary thyroid carcinoma and lymphocytic infiltration in the thyroid gland. Journal of Clinical Endocrinology and Metabolism, 80, 3421 3424.
13. Gupta, S., Patel, A., Folstad, A. et al. (2001) Infiltration of differentiated thyroid carcinoma by proliferating lymphocytes is associated with improved disease-free survival for children and young adults. Journal of Clinical Endocrinology and Metabolism, 86, 1346 1354.
14. Yano, Y., Shibuya, H., Kitagawa, W. et al. (2007) Recent outcome of Graves' disease patients with papillary thyroid cancer. European Journal of Endocrinology, 157, 325 329.
15. Fugazzola, L., Puxeddu, E., Avenia, N. et al. (2006) Correlation between B-RAFV600E mutation and clinico-pathologic parameters in papillary thyroid carcinoma: data from a multicentric Italian study and review of the literature. Endocrine Related Cancer, 13, 455 464.
16. Alberti, L., Carniti, C., Miranda, C. et al. (2003) RET and NTRK1 proto-oncogenes in human diseases. Journal of Cellular Physiology, 195, 168 186.
17. Rosai, J. (2004) Autoimmune (lymphocytic and Hashimoto's) thyroiditis. In : J. Rosai ed. Rosai and Ackerman's Surgical Pathology, Vol. 1, 9th edn. Mosby Publisher, MO, USA, 520 523.
18. Hedinger, C. (1988) Histological Typing of Thyroid Tumors: WHO International Histological Classification of Tumors, 2nd edn. Springer-Verlag, Berlin, Heidelberg.
19. American Joint Committee of Cancer (2002) Cancer staging manual. In : F.L. Greene, D.L. Page, I.D. Fleming, A.G. Fritz, C.M. Balch, D.G. Heller, M. Morrow eds. TNM classification of malignant tumors, 6th edn. Springer-Verlag, New York, 89 98.
20. Pacini, F., Schlumberger, M., Dralle, H. et al. (2006) European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium. European Journal of Endocrinology, 154, 787 803.
21. Cooper, D.S., Doherty, G.M., Haugen, B.R. et al. (2006) Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid, 16, 109 142.
22. Perrino, M., Vannucchi, G., Vicentini, L. et al. (2009) Outcome predictors and impact of central node dissection and radiometabolic treatments in papillary thyroid cancers ≤2 cm. Endocrine Related Cancer, 16, 201 210.
23. Frattini, M., Ferrario, C., Bressan, P. et al. (2004) Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer. Oncogene, 23, 7436 7440.
24. Castellone, M.D., Guarino, V., De Falco, V. et al. (2004) Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas. Oncogene, 23, 5958 5967.
25. Wirtschafter, A., Schmidt, R., Rosen, D. et al. (1997) Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis. Laryngoscope, 107, 95 100.
26. Sheils, O.M., O'Eary, J.J., Uhlmann, V. et al. (2000) Ret/PTC-1 activation in Hashimoto thyroiditis. International Journal of Surgical Pathology, 8, 185 189.
27. Nikiforova, M., Caudill, C., Biddinger, P. et al. (2002) Prevalence of RET/PTC rearrangements in Hashimoto thyroiditis and papillary thyroid carcinoma. International Journal of Surgical Pathology, 10, 15 22.
28. Rhoden, K.J., Unger, K., Salvatore, G. et al. (2006) RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma. Journal of Clinical Endocrinology and Metabolism, 91, 2414 2423.
29. Powell, D.J. Jr., Eisenlohr, L.C. Rothstein, J.L. (2003) A thyroid tumor-specific antigen formed by the fusion of two self proteins. Journal of Immunology, 170, 861 869.
30. Scarpino, S., Stoppacciaro, A., Ballerini, F. et al. (2000) Papillary carcinoma of the thyroid: hepatocyte growth factor (HGF) stimulates tumor cells to release chemokines active in recruiting dendritic cells. American Journal of Pathology, 156, 831 837.