Mechanical resolution of chiral objects in achiral media: Where is the size limit?

Chirality

Volumn 23, Issue 2, 2011, Pages 144-147

  Tencer, Michal ^a,b   Bielski, Roman ^c  

^a UNIVERSITY OF OTTAWA   (Canada)

^b MST Consulting   (Canada)

^c Value Recovery Inc   (United States)

Author keywords

achiral media; Brownian motion; chirality; friction; hydrodynamic; mechanical; orientation; resolution; rotational diffusion; sedimentation

Indexed keywords

ARTICLE; CHIRALITY; ELECTRIC FIELD; HYDRODYNAMICS; MOLECULAR SIZE; MOTION; PARTICLE SIZE; PRIORITY JOURNAL; SPATIAL ORIENTATION;

EID: 78650928484     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20892     Document Type: Article

References (24)

1. Müller UF,. Re-creating an RNA world. Cell Mol Life Sci 2006; 63: 1278-1293.
2. Caetano-Anollés G, Wang M, Caetano-Anollés D, Mittenthal JE,. The origin, evolution and structure of the protein world. Biochem J 2009; 417: 621-637.
3. Ikehara K,. Possible steps to the emergence of life: the [GADV]-protein world hypothesis. Chem Rec 2005; 5: 107-118.
4. Hanslmeier A,. Habitability and cosmic catastrophes (advances in astrobiology and biogeophysics), chapter 2. Heidelberg: Springer Berlin; 2009.
5. Rauchfuss H,. Chemical evolution and the origin of life, chapter 9. Heidelberg: Springer Berlin; 2008.
6. Fogassy E, Nógrádi M, Kozma D, Egri G, Pálovics E, Kiss V,. Optical resolution methods. Org Biomol Chem 2006; 4: 3011-3030.
7. Bielski R, Tencer M,. Absolute enantioselective separation: optical activity ex machina. J Sep Sci 2005; 28: 2325-2332.
8. Hazen RM, Sholl DS,. Chiral selection on inorganic crystalline surfaces. Nat Mater 2003; 2: 367-374.
9. Lever I,. The left-right phenomenon; sorting of lamellibranch bivalves on sandy beaches. Basteria 1958; 22: 21-51.
10. Nagle JS,. Differential sorting of shells in the swash zone. Biol Bull 1964; 127: 353.
11. Nagle JS,. Wave and current orientation of shells. J Sedimentary Petrol 1967; 37: 1124-1138.
12. Globe and Mail. Six severed feet wash up on coast. Toronto: Globe and Mail, June 21; 2008.
13. Howard DW, Lightfoot E, Hirschfelder JO,. The hydrodynamic resolution of optical isomers. AIChE J 1976; 22: 794-798.
14. Hirschfelder JO, Lightfoot EN, Howard DW,. Hydrodynamic method for separation of solid bodies and crystals, US Patent 4,010,095, 1977.
15. de Gennes PG,. Mechanical selection of chiral crystals. Europhys Lett 1999; 46: 827-831.
16. Welch CJ,. Some thoughts concerning the separation of enantiomers without the use of enantioenriched materials or forces. Enantiomer 1998; 3: 275-281.
17. Feynman RP, Leighton RB, Sands M,. The Feynman lectures on physics, Vol. I, Chapter 46. Reading, MA: Addison-Wesley; 1966.
18. Bielski R, Tencer M,. Macroscopically chiral system of three independent orientational effects as a condition for the absolute asymmetric synthesis. Can J Chem 2003; 81: 1029-1037.
19. Hunter RJ,. Foundations of colloid science. New York: Oxford University Press, Oxford; 2001.
20. Debye P,. Polar molecules, Chemical Catalog Co: Reinholt Publishing Co; 1929.
21. Einstein A,. Investigations on the theory of brownian movement. In:, Fűrth A, editor: Dover Publications; 1956.
22. Smoluchowski M,. Essai d'une théorie cinétique du mouvement Brownien et des milieux troubles. Bulletin International de l'Académie des Sciences de Cracovie 1906: 577-602.
23. Tencer M,. Deposition of aerosol ("hygroscopic dust") on electronics-mechanism and risk. Microel Reliab 2008; 48: 584-593; references cited therein.
24. Mastai Y, Völkel A, Colfen H,. Separation of racemate from excess enantiomer of chiral nonracemic compounds via density gradient ultracentrifugation. J Am Chem Soc 2008; 130: 2426-2427.