Sequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromes

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Sadikovic, Bekim ^a   Wang, Jing ^a   El Hattab, Ayman ^a   Landsverk, Megan ^a   Douglas, Ganka ^a   Brundage, Ellen K ^a   Craigen, William J ^a   Schmitt, Eric S ^a   Wong, Lee Jun C ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHROMOSOME BREAKAGE; CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; CLINICAL FEATURE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA DETERMINATION; DNA SEQUENCE; GENE DELETION; HETEROPLASMY; HUMAN; INFANT; KEARNS SAYRE SYNDROME; MAJOR CLINICAL STUDY; MITOCHONDRIAL DNA DEPLETION SYNDROME; MITOCHONDRIAL MYOPATHY; ONSET AGE; PEARSON SYNDROME; PHENOTYPE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SCHOOL CHILD; SEQUENCE HOMOLOGY; AGED; CHROMOSOME; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENETICS; METHODOLOGY; MIDDLE AGED; MUTATION; NEWBORN; ULTRASTRUCTURE;

ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; CHROMOSOMES; DNA, MITOCHONDRIAL; GENE DELETION; HUMANS; INFANT; INFANT, NEWBORN; KEARNS-SAYRE SYNDROME; MIDDLE AGED; MITOCHONDRIAL DISEASES; MUTATION; OPHTHALMOPLEGIA, CHRONIC PROGRESSIVE EXTERNAL; PHENOTYPE; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION;

EID: 78650895885     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015687     Document Type: Article

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