메뉴 건너뛰기




Volumn 38, Issue 1, 2011, Pages 87-98

Whole-blood gene expression profiling in ankylosing spondylitis shows upregulation of Toll-like receptor 4 and 5

Author keywords

Ankylosing spondylitis; Autoimmunity; Bacteria; Gene expression profiling; Immune system; Toll like receptors

Indexed keywords

TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR INHIBITOR;

EID: 78650894265     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.100469     Document Type: Article
Times cited : (73)

References (37)
  • 1
    • 35748981184 scopus 로고    scopus 로고
    • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    • Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007;39:1329-37.
    • (2007) Nat Genet , vol.39 , pp. 1329-1337
    • Burton, P.R.1    Clayton, D.G.2    Cardon, L.R.3    Craddock, N.4    Deloukas, P.5    Duncanson, A.6
  • 2
    • 67149147284 scopus 로고    scopus 로고
    • Genetics and the pathogenesis of ankylosing spondylitis
    • Brown MA. Genetics and the pathogenesis of ankylosing spondylitis. Curr Opin Rheumatol 2009;21:318-23.
    • (2009) Curr Opin Rheumatol , vol.21 , pp. 318-323
    • Brown, M.A.1
  • 3
    • 34247164611 scopus 로고    scopus 로고
    • Ankylosing spondylitis
    • Braun J, Sieper J. Ankylosing spondylitis. Lancet 2007;369:1379-90.
    • (2007) Lancet , vol.369 , pp. 1379-1390
    • Braun, J.1    Sieper, J.2
  • 4
    • 0036791989 scopus 로고    scopus 로고
    • Clues to pathogenesis of spondyloarthropathy derived from synovial fluid mononuclear cell gene expression profiles
    • Gu J, Rihl M, Marker-Hermann E, Baeten D, Kuipers JG, Song YW, et al. Clues to pathogenesis of spondyloarthropathy derived from synovial fluid mononuclear cell gene expression profiles. J Rheumatol 2002;29:2159-64.
    • (2002) J Rheumatol , vol.29 , pp. 2159-2164
    • Gu, J.1    Rihl, M.2    Marker-Hermann, E.3    Baeten, D.4    Kuipers, J.G.5    Song, Y.W.6
  • 5
    • 55849134446 scopus 로고    scopus 로고
    • Identification of interleukin-7 as a candidate disease mediator in spondylarthritis
    • Rihl M, Kellner H, Kellner W, Barthel C, Yu DT, Tak PP, et al. Identification of interleukin-7 as a candidate disease mediator in spondylarthritis. Arthritis Rheum 2008;58:3430-5.
    • (2008) Arthritis Rheum , vol.58 , pp. 3430-3435
    • Rihl, M.1    Kellner, H.2    Kellner, W.3    Barthel, C.4    Yu, D.T.5    Tak, P.P.6
  • 6
    • 0036316378 scopus 로고    scopus 로고
    • A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients
    • Gu J, Marker-Hermann E, Baeten D, Tsai WC, Gladman D, Xiong M, et al. A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients. Rheumatology 2002;41:759-66.
    • (2002) Rheumatology , vol.41 , pp. 759-766
    • Gu, J.1    Marker-Hermann, E.2    Baeten, D.3    Tsai, W.C.4    Gladman, D.5    Xiong, M.6
  • 7
    • 45349092221 scopus 로고    scopus 로고
    • Gene expression analysis of macrophages derived from ankylosing spondylitis patients reveals interferon-gamma dysregulation
    • Smith JA, Barnes MD, Hong D, DeLay ML, Inman RD, Colbert RA. Gene expression analysis of macrophages derived from ankylosing spondylitis patients reveals interferon-gamma dysregulation. Arthritis Rheum 2008;58:1640-9.
    • (2008) Arthritis Rheum , vol.58 , pp. 1640-1649
    • Smith, J.A.1    Barnes, M.D.2    Hong, D.3    Delay, M.L.4    Inman, R.D.5    Colbert, R.A.6
  • 8
    • 77956021396 scopus 로고    scopus 로고
    • Gene expression profiling reveals a downregulation in immune-associated genes in patients with AS
    • Duan R, Leo P, Bradbury L, Brown MA, Thomas GP. Gene expression profiling reveals a downregulation in immune-associated genes in patients with AS. Ann Rheum Dis 2010;69:1724-9.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1724-1729
    • Duan, R.1    Leo, P.2    Bradbury, L.3    Brown, M.A.4    Thomas, G.P.5
  • 9
    • 4344680233 scopus 로고    scopus 로고
    • Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation
    • Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Moser K, Ortmann WA, et al. Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation. Genes Immun 2004;5:347-53.
    • (2004) Genes Immun , vol.5 , pp. 347-353
    • Baechler, E.C.1    Batliwalla, F.M.2    Karypis, G.3    Gaffney, P.M.4    Moser, K.5    Ortmann, W.A.6
  • 10
    • 0021969315 scopus 로고
    • Evaluation of diagnostic criteria for ankylosing spondylitis: A comparison of the Rome, New York and modified New York criteria in patients with a positive clinical history screening test for ankylosing spondylitis
    • Goie The HS, Steven MM, van der Linden SM, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis: a comparison of the Rome, New York and modified New York criteria in patients with a positive clinical history screening test for ankylosing spondylitis. Br J Rheumatol 1985;24:242-9.
    • (1985) Br J Rheumatol , vol.24 , pp. 242-249
    • Goie The, H.S.1    Steven, M.M.2    Van Der Linden, S.M.3    Cats, A.4
  • 11
    • 0018887574 scopus 로고
    • Preliminary criteria for the classification of systemic sclerosis (scleroderma)
    • Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee
    • Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980;23:581-90.
    • (1980) Arthritis Rheum , vol.23 , pp. 581-590
  • 13
    • 5044238637 scopus 로고    scopus 로고
    • The Systemic Lupus Activity Measure-revised, the Mexican Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), and a modified SLEDAI-2K are adequate instruments to measure disease activity in systemic lupus erythematosus
    • Uribe AG, Vila LM, McGwin G Jr, Sanchez ML, Reveille JD, Alarcon GS. The Systemic Lupus Activity Measure-revised, the Mexican Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), and a modified SLEDAI-2K are adequate instruments to measure disease activity in systemic lupus erythematosus. J Rheumatol 2004;31:1934-40.
    • (2004) J Rheumatol , vol.31 , pp. 1934-1940
    • Uribe, A.G.1    Vila, L.M.2    Jr, M.G.3    Sanchez, M.L.4    Reveille, J.D.5    Alarcon, G.S.6
  • 14
    • 0348143180 scopus 로고    scopus 로고
    • A random variance model for detection of differential gene expression in small microarray experiments
    • Wright GW, Simon RM. A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics 2003;19:2448-55.
    • (2003) Bioinformatics , vol.19 , pp. 2448-2455
    • Wright, G.W.1    Simon, R.M.2
  • 16
    • 0028823453 scopus 로고
    • The evolution of spondyloarthropathies in relation to gut histology. II. Histological aspects
    • Mielants H, Veys EM, Cuvelier C, De Vos M, Goemaere S, De Clercq L, et al. The evolution of spondyloarthropathies in relation to gut histology. II. Histological aspects. J Rheumatol 1995;22:2273-8.
    • (1995) J Rheumatol , vol.22 , pp. 2273-2278
    • Mielants, H.1    Veys, E.M.2    Cuvelier, C.3    De Vos, M.4    Goemaere, S.5    De Clercq, L.6
  • 17
    • 0028003794 scopus 로고
    • The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats
    • Taurog JD, Richardson JA, Croft JT, Simmons WA, Zhou M, Fernandez-Sueiro JL, et al. The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats. J Exp Med 1994;180:2359-64.
    • (1994) J Exp Med , vol.180 , pp. 2359-2364
    • Taurog, J.D.1    Richardson, J.A.2    Croft, J.T.3    Simmons, W.A.4    Zhou, M.5    Fernandez-Sueiro, J.L.6
  • 18
    • 33947629255 scopus 로고    scopus 로고
    • Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
    • Miyake K. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin Immunol 2007;19:3-10.
    • (2007) Semin Immunol , vol.19 , pp. 3-10
    • Miyake, K.1
  • 20
    • 0036467447 scopus 로고    scopus 로고
    • Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway
    • Bulut Y, Faure E, Thomas L, Karahashi H, Michelsen KS, Equils O, et al. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J Immunol 2002;168:1435-40.
    • (2002) J Immunol , vol.168 , pp. 1435-1440
    • Bulut, Y.1    Faure, E.2    Thomas, L.3    Karahashi, H.4    Michelsen, K.S.5    Equils, O.6
  • 22
    • 0041823554 scopus 로고    scopus 로고
    • Role of Toll-like receptor 4 in macrophage activation and tolerance during Salmonella enterica serovar Typhimurium infection
    • Li Q, Cherayil BJ. Role of Toll-like receptor 4 in macrophage activation and tolerance during Salmonella enterica serovar Typhimurium infection. Infect Immun 2003;71:4873-82.
    • (2003) Infect Immun , vol.71 , pp. 4873-4882
    • Li, Q.1    Cherayil, B.J.2
  • 23
    • 22244489703 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha blockade treatment down-modulates the increased systemic and local expression of Toll-like receptor 2 and Toll-like receptor 4 in spondylarthropathy
    • De Rycke L, Vandooren B, Kruithof E, De Keyser F, Veys EM, Baeten D. Tumor necrosis factor alpha blockade treatment down-modulates the increased systemic and local expression of Toll-like receptor 2 and Toll-like receptor 4 in spondylarthropathy. Arthritis Rheum 2005;52:2146-58.
    • (2005) Arthritis Rheum , vol.52 , pp. 2146-2158
    • De Rycke, L.1    Vandooren, B.2    Kruithof, E.3    De Keyser, F.4    Veys, E.M.5    Baeten, D.6
  • 24
    • 34250214572 scopus 로고    scopus 로고
    • Increased expression of Toll-like receptor 4 in peripheral blood leucocytes and serum levels of some cytokines in patients with ankylosing spondylitis
    • Yang ZX, Liang Y, Zhu Y, Li C, Zhang LZ, Zeng XM, et al. Increased expression of Toll-like receptor 4 in peripheral blood leucocytes and serum levels of some cytokines in patients with ankylosing spondylitis. Clin Exp Immunol 2007;149:48-55.
    • (2007) Clin Exp Immunol , vol.149 , pp. 48-55
    • Yang, Z.X.1    Liang, Y.2    Zhu, Y.3    Li, C.4    Zhang, L.Z.5    Zeng, X.M.6
  • 25
    • 0028012550 scopus 로고
    • O, K, and H antigens predict virulence factors, carboxylesterase B pattern, antimicrobial resistance, and host compromise among Escherichia coli strains causing urosepsis
    • Johnson JR, Orskov I, Orskov F, Goullet P, Picard B, Moseley SL, et al. O, K, and H antigens predict virulence factors, carboxylesterase B pattern, antimicrobial resistance, and host compromise among Escherichia coli strains causing urosepsis. J Infect Dis 1994;169:119-26.
    • (1994) J Infect Dis , vol.169 , pp. 119-126
    • Johnson, J.R.1    Orskov, I.2    Orskov, F.3    Goullet, P.4    Picard, B.5    Moseley, S.L.6
  • 26
    • 0022608664 scopus 로고
    • Studies on the serology of flagellar antigens of Yersinia enterocolitica and related Yersinia species
    • Aleksic S, Bockemuhl J, Lange F. Studies on the serology of flagellar antigens of Yersinia enterocolitica and related Yersinia species. Zentralbl Bakteriol Mikrobiol Hyg A 1986;261:299-310.
    • (1986) Zentralbl Bakteriol Mikrobiol Hyg A , vol.261 , pp. 299-310
    • Aleksic, S.1    Bockemuhl, J.2    Lange, F.3
  • 27
    • 0021845419 scopus 로고
    • Production of potent Salmonella H antisera by immunization with polymeric flagellins
    • Ibrahim GF, Fleet GH, Lyons MJ, Walker RA. Production of potent Salmonella H antisera by immunization with polymeric flagellins. J Clin Microbiol 1985;22:347-51.
    • (1985) J Clin Microbiol , vol.22 , pp. 347-351
    • Ibrahim, G.F.1    Fleet, G.H.2    Lyons, M.J.3    Walker, R.A.4
  • 28
    • 33947323718 scopus 로고    scopus 로고
    • TLRs in the gut. III. Immune responses to flagellin in Crohn's's disease: Good, bad or irrelevant?
    • Gewirtz AT. TLRs in the gut. III. Immune responses to flagellin in Crohn's's disease: good, bad, or irrelevant? Am J Physiol Gastrointest Liver Physiol 2007;292:G706-G710.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Gewirtz, A.T.1
  • 30
    • 26444440067 scopus 로고    scopus 로고
    • Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation
    • Rhee SH, Im E, Riegler M, Kokkotou E, O'Brien M, Pothoulakis C. Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci USA 2005;102:13610-5.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13610-13615
    • Rhee, S.H.1    Im, E.2    Riegler, M.3    Kokkotou, E.4    O'brien, M.5    Pothoulakis, C.6
  • 32
  • 33
    • 20144371035 scopus 로고    scopus 로고
    • Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis
    • Kruithof E, Baeten D, De Rycke L, Vandooren B, Foell D, Roth J, et al. Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis. Arthritis Res Ther 2005;7:R569-80.
    • (2005) Arthritis Res Ther , vol.7
    • Kruithof, E.1    Baeten, D.2    De Rycke, L.3    Vandooren, B.4    Foell, D.5    Roth, J.6
  • 34
    • 0036187210 scopus 로고    scopus 로고
    • Macrophages expressing the scavenger receptor CD163: A link between immune alterations of the gut and synovial inflammation in spondyloarthropathy
    • Baeten D, Demetter P, Cuvelier CA, Kruithof E, Van Damme N, De Vos M, et al. Macrophages expressing the scavenger receptor CD163: a link between immune alterations of the gut and synovial inflammation in spondyloarthropathy. J Pathol 2002;196:343-50.
    • (2002) J Pathol , vol.196 , pp. 343-350
    • Baeten, D.1    Demetter, P.2    Cuvelier, C.A.3    Kruithof, E.4    Van Damme, N.5    De Vos, M.6
  • 35
    • 33847786702 scopus 로고    scopus 로고
    • Up-regulation of human monocyte CD163 upon activation ofcell-surface Toll-like receptors
    • Weaver LK, Pioli PA, Wardwell K, Vogel SN, Guyre PM. Up-regulation of human monocyte CD163 upon activation ofcell-surface Toll-like receptors. J Leukoc Biol 2007;81:663-71.
    • (2007) J Leukoc Biol , vol.81 , pp. 663-671
    • Weaver, L.K.1    Pioli, P.A.2    Wardwell, K.3    Vogel, S.N.4    Guyre, P.M.5
  • 36
    • 28044463780 scopus 로고    scopus 로고
    • Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages
    • Jiang W, Sun R, Wei H, Tian Z. Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages. Proc Natl Acad Sci USA 2005;102:17077-82.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 17077-17082
    • Jiang, W.1    Sun, R.2    Wei, H.3    Tian, Z.4
  • 37
    • 55849093579 scopus 로고    scopus 로고
    • Correlation between dendritic cell functional defect and spondylarthritis phenotypes in HLA-B27/Human beta2-microglobulin-transgenic rat lines
    • Fert I, Glatigny S, Poulain C, Satumtira N, Dorris ML, Taurog JD, et al. Correlation between dendritic cell functional defect and spondylarthritis phenotypes in HLA-B27/Human beta2-microglobulin-transgenic rat lines. Arthritis Rheum 2008;58:3425-9.
    • (2008) Arthritis Rheum , vol.58 , pp. 3425-3429
    • Fert, I.1    Glatigny, S.2    Poulain, C.3    Satumtira, N.4    Dorris, M.L.5    Taurog, J.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.