Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions

Biochemical and Biophysical Research Communications

Volumn 404, Issue 1, 2011, Pages 407-412

  Zhang, Yanfeng ^a   Buchko, Garry W ^a   Qin, Ling ^b   Robinson, Howard ^c   Varnum, Susan M ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b Michigan State University   (United States)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

Botulinum neurotoxin; Botulism; C D mosaic; Membrane recognition; Phosphatidylethanolamine

Indexed keywords

BOTULINUM TOXIN; LYSINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BOTULISM; CARBOXY TERMINAL SEQUENCE; CLOSTRIDIUM BOTULINUM TYPE C; CLOSTRIDIUM BOTULINUM TYPE D; CRYSTAL STRUCTURE; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR BINDING; SYNAPTOSOME;

ANIMALS; BOTULINUM TOXINS; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIPOSOMES; LYSINE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHATIDYLETHANOLAMINES; PHOSPHOLIPIDS; PROTEIN STRUCTURE, TERTIARY;

ANIMALIA; BACTERIA (MICROORGANISMS); CLOSTRIDIUM BOTULINUM; LOTUS;

EID: 78650892621     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.11.134     Document Type: Article

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