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Volumn 11, Issue 1, 2011, Pages 97-105

Cardiovascular effects of glucagon-like peptide 1

Author keywords

Arterial blood pressure; Cardiovascular; Endothelium; Glucagon like peptide 1; Heart failure; Left ventricular function; Type 2 diabetes mellitus

Indexed keywords

EXENDIN 4; EXENDIN[9-39]; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE; GLUCOSE; LIRAGLUTIDE; RECOMBINANT GLUCAGON LIKE PEPTIDE 1; UNCLASSIFIED DRUG;

EID: 78650889026     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955711793564033     Document Type: Article
Times cited : (7)

References (52)
  • 1
    • 34447267513 scopus 로고    scopus 로고
    • Efficacy and safety of incretin therapy in type 2 diabetes: Systematic reviewand meta-analysis
    • Amori, R.E.; Lau, J.; Pittas, A.G. Efficacy and safety of incretin therapy in type 2 diabetes: systematic reviewand meta-analysis. JAMA, 2007, 298, 194-206.
    • (2007) JAMA , vol.298 , pp. 194-206
    • Amori, R.E.1    Lau, J.2    Pittas, A.G.3
  • 2
    • 65349085059 scopus 로고    scopus 로고
    • Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005
    • Preis, S.R.; Hwang, S.J.; Coady, S.; Pencina, M.J.; D'Agostino, R.B.Sr.; Savage, P.J.; Levy, D.; Fox, C.S. Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005. Circulation, 2009, 119, 1728-1735.
    • Circulation , vol.2009 , pp. 1728-1735
    • Preis, S.R.1    Hwang, S.J.2    Coady, S.3    Pencina, M.J.4    D'Agostino Sr, R.B.5    Savage, P.J.6    Levy, D.7    Fox, C.S.8
  • 3
    • 0035434115 scopus 로고    scopus 로고
    • Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor
    • Burcelin, R.; Da Costa, A.; Drucker, D.; Thorens, B. Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes, 2001, 50, 1720-1728.
    • (2001) Diabetes , vol.50 , pp. 1720-1728
    • Burcelin, R.1    da Costa, A.2    Drucker, D.3    Thorens, B.4
  • 4
    • 0031916924 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig
    • Deacon, C.F.; Hughes, T.E.; Holst, J.J. Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig. Diabetes, 1998, 47, 764-769.
    • (1998) Diabetes , vol.47 , pp. 764-769
    • Deacon, C.F.1    Hughes, T.E.2    Holst, J.J.3
  • 5
    • 0028803336 scopus 로고
    • Both subcutaneously and intravenously administered glucagon-like peptide 1 are rapidly degraded from the NH2- terminus in type 2-diabetic patients and in healthy subjects
    • Deacon, C.F.; Nauck, M.A.; Toft-Nielsen, M.; Pridal, L.; Willms, B.; Host, J.J. Both subcutaneously and intravenously administered glucagon-like peptide 1 are rapidly degraded from the NH2- terminus in type 2-diabetic patients and in healthy subjects. Diabetes, 1995, 44, 1126-1131.
    • (1995) Diabetes , vol.44 , pp. 1126-1131
    • Deacon, C.F.1    Nauck, M.A.2    Toft-Nielsen, M.3    Pridal, L.4    Willms, B.5    Host, J.J.6
  • 6
    • 0028978243 scopus 로고
    • +)- signalling pathway in pancreatic beta-cells by the insulinotropic hormone glucagon-like peptide-1
    • +)- signalling pathway in pancreatic beta-cells by the insulinotropic hormone glucagon-like peptide-1. J. Biol. Chem., 1995, 270, 17749-17757.
    • (1995) J. Biol. Chem , vol.270 , pp. 17749-17757
    • Holz, G.G.1    Leech, C.A.2    Habener, J.F.3
  • 7
    • 0028900758 scopus 로고
    • Tissue-specific expression of the human receptor for glucagon-like peptide-I: Brain, heart and pancreatic forms have the same deduced amino acid sequences
    • Wei, Y.; Mojsov, S. Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences. FEBS Lett., 1995, 358, 219-224.
    • (1995) FEBS Lett , vol.358 , pp. 219-224
    • Wei, Y.1    Mojsov, S.2
  • 8
    • 0344357096 scopus 로고
    • Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line
    • Drucker, D.J.; Philippe, J.; Mojsov, S.; Chick, W.L.; Habener, J.F. Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. Proc. Natl. Acad. Sci. USA., 1987, 84, 3434-3438.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3434-3438
    • Drucker, D.J.1    Philippe, J.2    Mojsov, S.3    Chick, W.L.4    Habener, J.F.5
  • 9
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • Drucker, D.J. The biology of incretin hormones. Cell Metab., 2006, 3, 153-165.
    • (2006) Cell Metab , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 10
    • 0028042205 scopus 로고
    • Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1- (7-36) amide in rats
    • Barragán, J.M.; Rodríguez, R.E.; Blázquez, E. Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1- (7-36) amide in rats. Am. J. Physiol., 1994, 266, 459-466.
    • (1994) Am. J. Physiol , vol.266 , pp. 459-466
    • Barragán, J.M.1    Rodríguez, R.E.2    Blázquez, E.3
  • 11
    • 0030583731 scopus 로고    scopus 로고
    • Interactions of exendin-(9-39) with the effects of glucagon-like peptide-1-(7-36) amide and of exendin-4 on arterial blood pressure and heart rate in rats
    • Barragán, J.M.; Rodríguez, R.E.; Eng, J.; Blázquez, E. Interactions of exendin-(9-39) with the effects of glucagon-like peptide-1-(7-36) amide and of exendin-4 on arterial blood pressure and heart rate in rats. Regul. Pept., 1996, 67, 63-68.
    • (1996) Regul. Pept , vol.67 , pp. 63-68
    • Barragán, J.M.1    Rodríguez, R.E.2    Eng, J.3    Blázquez, E.4
  • 12
    • 0038202937 scopus 로고    scopus 로고
    • Antihypertensive effect of glucagon-like peptide 1 in Dahl salt-sensitive rats
    • Yu, M.; Moreno, C.; Hoagland, K.M.; Dahly, A.; Ditter, K.; Mistry, M.; Roman, R.J. Antihypertensive effect of glucagon-like peptide 1 in Dahl salt-sensitive rats. J. Hypertens., 2003, 21, 1125-1135.
    • (2003) J. Hypertens , vol.21 , pp. 1125-1135
    • Yu, M.1    Moreno, C.2    Hoagland, K.M.3    Dahly, A.4    Ditter, K.5    Mistry, M.6    Roman, R.J.7
  • 15
    • 0032714917 scopus 로고    scopus 로고
    • Neural contribution to the effect of glucagon-like peptide-1-(7-36) amide on arterial blood pressure in rats
    • Barragán, J.M.; Eng, J.; Rodríguez, R.; Blázquez, E. Neural contribution to the effect of glucagon-like peptide-1-(7-36) amide on arterial blood pressure in rats. Am. J. Physiol., 1999, 277, E784-91.
    • (1999) Am. J. Physiol , vol.277 , pp. 784-791
    • Barragán, J.M.1    Eng, J.2    Rodríguez, R.3    Blázquez, E.4
  • 17
    • 0842346377 scopus 로고    scopus 로고
    • Effects of intracerebroventricularly injected glucagon-like peptide-1 on cardiovascular parameters; role of central cholinergic system and vasopressin
    • Isbil-Buyukcoskun, N.; Gulec, G. Effects of intracerebroventricularly injected glucagon-like peptide-1 on cardiovascular parameters; role of central cholinergic system and vasopressin. Regul. Pept., 2004, 118, 33-38.
    • (2004) Regul. Pept , vol.118 , pp. 33-38
    • Isbil-Buyukcoskun, N.1    Gulec, G.2
  • 19
    • 0035980166 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes
    • Vila Petroff, M.G.; Egan, J.M.; Wang, X.; Sollott, S.J. Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes. Circ. Res., 2001, 89, 445-452.
    • (2001) Circ. Res , vol.89 , pp. 445-452
    • Vila Petroff, M.G.1    Egan, J.M.2    Wang, X.3    Sollott, S.J.4
  • 20
    • 9944251347 scopus 로고    scopus 로고
    • Glucagon-likepeptide-1 relaxes rat conduit arteries via an endothelium-independent mechanism
    • Nyström, T.; Gonon, A.T.; Sjöholm, A.; Pernow, J. Glucagon-likepeptide-1 relaxes rat conduit arteries via an endothelium-independent mechanism. Regul. Pept., 2005, 125, 173-177.
    • (2005) Regul. Pept , vol.125 , pp. 173-177
    • Nyström, T.1    Gonon, A.T.2    Sjöholm, A.3    Pernow, J.4
  • 22
    • 0037629509 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium
    • Kavianipour, M.; Ehlers, M.R.; Malmberg, K.; Ronquist, G.; Ryden, L.; Wikström, G.; Gutniak, M. Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium. Peptides, 2003, 24, 569-578.
    • (2003) Peptides , vol.24 , pp. 569-578
    • Kavianipour, M.1    Ehlers, M.R.2    Malmberg, K.3    Ronquist, G.4    Ryden, L.5    Wikström, G.6    Gutniak, M.7
  • 23
    • 4344605042 scopus 로고    scopus 로고
    • Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy
    • Nikolaidis, L.A.; Elahi, D.; Hentosz, T.; Doverspike, A.; Huerbin, R.; Zourelias, L.; Stolarski, C.; Shen, Y.T.; Shannon, R.P. Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy. Circulation, 2004, 110, 955-961.
    • (2004) Circulation , vol.110 , pp. 955-961
    • Nikolaidis, L.A.1    Elahi, D.2    Hentosz, T.3    Doverspike, A.4    Huerbin, R.5    Zourelias, L.6    Stolarski, C.7    Shen, Y.T.8    Shannon, R.P.9
  • 24
    • 28144441354 scopus 로고    scopus 로고
    • Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy
    • Nikolaidis, L.A.; Elahi, D.; Shen, Y.T.; Shannon, R.P. Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy. Am. J. Physiol. Heart Circ. Physiol., 2005, 289, H2401-408.
    • (2005) Am. J. Physiol. Heart Circ. Physiol , vol.289 , pp. 2401-2408
    • Nikolaidis, L.A.1    Elahi, D.2    Shen, Y.T.3    Shannon, R.P.4
  • 25
    • 11844269899 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 limits myocardial stunning following brief coronary occlusion and reper fusion in conscious canines
    • Nikolaidis, L.A.; Doverspike, A.; Hentosz, T.; Zourelias, L.; Shen, Y.T.; Elahi, D.; Shannon, R.P. Glucagon-like peptide-1 limits myocardial stunning following brief coronary occlusion and reper fusion in conscious canines. J. Pharmacol. Exp. Ther., 2005, 312, 303-308.
    • (2005) J. Pharmacol. Exp. Ther , vol.312 , pp. 303-308
    • Nikolaidis, L.A.1    Doverspike, A.2    Hentosz, T.3    Zourelias, L.4    Shen, Y.T.5    Elahi, D.6    Shannon, R.P.7
  • 26
    • 12144260853 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury
    • Bose, A.K.; Mocanu, M.M.; Carr, R.D.; Brand, C.L.; Yellon, D.M. Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury. Diabetes, 2005, 54, 146-151.
    • (2005) Diabetes , vol.54 , pp. 146-151
    • Bose, A.K.1    Mocanu, M.M.2    Carr, R.D.3    Brand, C.L.4    Yellon, D.M.5
  • 27
    • 20044367874 scopus 로고    scopus 로고
    • Glucagon like peptide-1 is protective against myocardial ischemia/reperfusion injury when given either as a preconditioning mimetic or at reper fusion in an isolated rat heart model
    • Bose, A.K.; Mocanu, M.M.; Carr, R.D.; Yellon, D.M. Glucagon like peptide-1 is protective against myocardial ischemia/reperfusion injury when given either as a preconditioning mimetic or at reper fusion in an isolated rat heart model. Cardiovasc. Drugs Ther., 2005, 19, 9-11.
    • (2005) Cardiovasc. Drugs Ther , vol.19 , pp. 9-11
    • Bose, A.K.1    Mocanu, M.M.2    Carr, R.D.3    Yellon, D.M.4
  • 28
    • 34548545405 scopus 로고    scopus 로고
    • Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway
    • Bose, A.K.; Mocanu, M.M.; Carr, R.D.; Yellon, D.M. Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway. Cardiovasc. Drugs Ther., 2007, 21, 253-256.
    • (2007) Cardiovasc. Drugs Ther , vol.21 , pp. 253-256
    • Bose, A.K.1    Mocanu, M.M.2    Carr, R.D.3    Yellon, D.M.4
  • 29
    • 33646795007 scopus 로고    scopus 로고
    • Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts
    • Zhao, T.; Parikh, P.; Bhashyam, S.; Bolukoglu, H.; Poornima, I.; Shen, Y.T.; Shannon, R.P. Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts. J. Pharmacol. Exp. Ther., 2006, 317, 1106-1113.
    • (2006) J. Pharmacol. Exp. Ther , vol.317 , pp. 1106-1113
    • Zhao, T.1    Parikh, P.2    Bhashyam, S.3    Bolukoglu, H.4    Poornima, I.5    Shen, Y.T.6    Shannon, R.P.7
  • 30
    • 38149083367 scopus 로고    scopus 로고
    • Protective effects of GLP- 1 analogues exendin-4 and GLP-1(9-36) amide against ischemia reperfusion injury in rat heart
    • Sonne, D.P.; Engstrøm, T.; Treiman, M. Protective effects of GLP- 1 analogues exendin-4 and GLP-1(9-36) amide against ischemia reperfusion injury in rat heart. Regul. Pept., 2008, 146, 243-249.
    • (2008) Regul. Pept , vol.146 , pp. 243-249
    • Sonne, D.P.1    Engstrøm, T.2    Treiman, M.3
  • 32
    • 58149342098 scopus 로고    scopus 로고
    • Effects and mechanism of glucagon-like peptide-1 on injury of rats cardiomyocytes induced by hypoxia reoxygenation
    • Xie, Y.; Wang, S.X.; Sha, W.W.; Zhou, X.; Wang, W.L.; Han, L.P.; Li, D.Q.; Yu, D.M. Effects and mechanism of glucagon-like peptide-1 on injury of rats cardiomyocytes induced by hypoxia reoxygenation. Chin Med. J. (Engl).,2008, 121, 2134-2138.
    • (2008) Chin Med. J. (Engl) , vol.121 , pp. 2134-2138
    • Xie, Y.1    Wang, S.X.2    Sha, W.W.3    Zhou, X.4    Wang, W.L.5    Han, L.P.6    Li, D.Q.7    Yu, D.M.8
  • 33
    • 45349103305 scopus 로고    scopus 로고
    • Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia
    • Huisamen, B.; Genade, S.; Lochner, A. Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia. Cardiovasc. J. Afr., 2008, 19, 77-83.
    • (2008) Cardiovasc. J. Afr , vol.19 , pp. 77-83
    • Huisamen, B.1    Genade, S.2    Lochner, A.3
  • 34
    • 43249089631 scopus 로고    scopus 로고
    • Cardioprotective and vasodilatory actions of glucagons like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways
    • Ban, K.; Noyan-Ashraf, M.H.; Hoefer, J.; Bolz, S.S.; Drucker, D.J.; Husain, M. Cardioprotective and vasodilatory actions of glucagons like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways. Circulation, 2008, 117, 2340-2350.
    • (2008) Circulation , vol.117 , pp. 2340-2350
    • Ban, K.1    Noyan-Ashraf, M.H.2    Hoefer, J.3    Bolz, S.S.4    Drucker, D.J.5    Husain, M.6
  • 35
  • 37
    • 33644682164 scopus 로고    scopus 로고
    • Initial experience with GLP-1 treatment on metabolic control and myocardial function in patients with type 2 diabetes mellitus and heart failure
    • Thrainsdottir, I.; Malmberg, K.; Olsson, A.; Gutniak, M.; Rydén, L. Initial experience with GLP-1 treatment on metabolic control and myocardial function in patients with type 2 diabetes mellitus and heart failure. Diab. Vasc. Dis. Res., 2004, 1, 40-43.
    • (2004) Diab. Vasc. Dis. Res , vol.1 , pp. 40-43
    • Thrainsdottir, I.1    Malmberg, K.2    Olsson, A.3    Gutniak, M.4    Rydén, L.5
  • 38
    • 33845293219 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure
    • Sokos, G.G.; Nikolaidis, L.A.; Mankad, S.; Elahi, D.; Shannon, R.P. Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure. J. Card. Fail., 2006, 12, 694-699.
    • (2006) J. Card. Fail , vol.12 , pp. 694-699
    • Sokos, G.G.1    Nikolaidis, L.A.2    Mankad, S.3    Elahi, D.4    Shannon, R.P.5
  • 39
    • 34547930879 scopus 로고    scopus 로고
    • Effect of glucagon-like peptide-1 (GLP-1) on glycemic control and left ventricular function in patients undergoing coronary artery bypass grafting
    • Sokos, G.G.; Bolukoglu, H.; German, J.; Hentosz, T.; Magovern, G.J; Benckart, D.H.; Elahi, D.; Effect of glucagon-like peptide-1 (GLP-1) on glycemic control and left ventricular function in patients undergoing coronary artery bypass grafting. Am. J. Cardiol., 2007, 100, 824-829.
    • (2007) Am. J. Cardiol. , vol.100 , pp. 824-829
    • Sokos, G.G.1    Bolukoglu, H.2    German, J.3    Hentosz, T.4    Magovern, G.J.5    Benckart, D.H.6    Elahi, D.7
  • 40
    • 1442311383 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion
    • Nikolaidis, L.A.; Mankad, S.; Sokos, G.G.; Miske, G.; Shah, A.; Elahi, D.; Shannon, R.P. Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion. Circulation, 2004, 109, 962-965.
    • (2004) Circulation , vol.109 , pp. 962-965
    • Nikolaidis, L.A.1    Mankad, S.2    Sokos, G.G.3    Miske, G.4    Shah, A.5    Elahi, D.6    Shannon, R.P.7
  • 43
    • 36148932551 scopus 로고    scopus 로고
    • Beneficial effects of GLP-1 on endothelial function in humans: Dampening by glyburide but not by glimepiride
    • Basu, A.; Charkoudian, N.; Schrage, W.; Rizza, R.A.; Basu, R.; Joyner, M.J. Beneficial effects of GLP-1 on endothelial function in humans: dampening by glyburide but not by glimepiride. Am. J. Physiol. Endocrinol. Metab., 2007, 293, E1289-295.
    • (2007) Am. J. Physiol. Endocrinol. Metab , vol.293 , pp. 1289-1295
    • Basu, A.1    Charkoudian, N.2    Schrage, W.3    Rizza, R.A.4    Basu, R.5    Joyner, M.J.6
  • 45
    • 0032768616 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3- kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)- cells
    • Buteau, J.; Roduit, R.; Susini, S.; Prentki, M. Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3- kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)- cells. Diabetologia, 1999, 42, 856-864.
    • (1999) Diabetologia , vol.42 , pp. 856-864
    • Buteau, J.1    Roduit, R.2    Susini, S.3    Prentki, M.4
  • 46
    • 1142309743 scopus 로고    scopus 로고
    • New directions for protecting the heart against ischemia-reperfusion injury: Targeting the reperfusion injury salvage kinase (RISK)-pathway
    • Hausenloy, D.J.; Yellon, D.M. New directions for protecting the heart against ischemia-reperfusion injury: targeting the reperfusion injury salvage kinase (RISK)-pathway. Cardiovasc. Res., 2004, 61. 448-460.
    • (2004) Cardiovasc. Res , vol.61 , pp. 448-460
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 47
    • 0034683064 scopus 로고    scopus 로고
    • Ischemic preconditioning activates phosphatidylinositol-3-kinase upstream of protein kinase
    • Tong, H.; Chen, W.; Steenbergen, C.; Murphy, E. Ischemic preconditioning activates phosphatidylinositol-3-kinase upstream of protein kinase C. Circ. Res., 2000, 87, 309-315.
    • (2000) C. Circ. Res , vol.87 , pp. 309-315
    • Tong, H.1    Chen, W.2    Steenbergen, C.3    Murphy, E.4
  • 48
    • 0036623989 scopus 로고    scopus 로고
    • PI3 kinase and not p44/42 appears to be implicated in the protection conferred by ischemic preconditioning
    • Mocanu, M.M.; Bell, R.M.; Yellon, D.M. PI3 kinase and not p44/42 appears to be implicated in the protection conferred by ischemic preconditioning. J. Mol. Cell Cardiol., 2002, 34, 661-668.
    • (2002) J. Mol. Cell Cardiol , vol.34 , pp. 661-668
    • Mocanu, M.M.1    Bell, R.M.2    Yellon, D.M.3
  • 49
    • 0029797540 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 undergoes differential tissue specific metabolism in the anesthetized pig
    • Deacon, C.F.; Pridal, L.; Klarskov, L.; Olesen, M.; Holst, J.J. Glucagon-like peptide-1 undergoes differential tissue specific metabolism in the anesthetized pig. Am. J. Physiol., 1996, 271, E458-64.
    • (1996) Am. J. Physiol , vol.271 , pp. 458-464
    • Deacon, C.F.1    Pridal, L.2    Klarskov, L.3    Olesen, M.4    Holst, J.J.5
  • 50
    • 0032976939 scopus 로고    scopus 로고
    • Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients
    • Toft-Nielsen, M.B.; Madsbad, S.; Holst, J.J. Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. Diabetes Care, 1999, 22, 1137-1143.
    • (1999) Diabetes Care , vol.22 , pp. 1137-1143
    • Toft-Nielsen, M.B.1    Madsbad, S.2    Holst, J.J.3
  • 51
    • 38549162147 scopus 로고    scopus 로고
    • Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
    • Klonoff, D.C.; Buse, J.B.; Nielsen, L.L.; Guan, X.; Bowlus, C.L.; Holcombe, J.H.; Wintle, M.E.; Maggs, D.G. Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years. Curr. Med. Res. Opin., 2008, 24, 275-286.
    • (2008) Curr. Med. Res. Opin , vol.24 , pp. 275-286
    • Klonoff, D.C.1    Buse, J.B.2    Nielsen, L.L.3    Guan, X.4    Bowlus, C.L.5    Holcombe, J.H.6    Wintle, M.E.7    Maggs, D.G.8
  • 52
    • 33846799072 scopus 로고    scopus 로고
    • Liraglutide: A once-daily GLP-1 analogue for the treatment of type 2 diabetes mellitus
    • Vilsbøll, T. Liraglutide: a once-daily GLP-1 analogue for the treatment of type 2 diabetes mellitus. Exp. Opin. Invest. Drug, 2007, 16, 231-237.
    • (2007) Exp. Opin. Invest. Drug , vol.16 , pp. 231-237
    • Vilsbøll, T.1


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