Total synthesis of the slime mold alkaloids arcyroxocin A and B

Synthesis

Volumn , Issue 2, 2011, Pages 330-336

  Mayer, Guido ^a   Wille, Gregor ^a   Brenner, Michael ^a   Zeitler, Kirsten ^a   Steglich, Wolfgang ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

alkaloids from myxomycetes; arcyroxocins; oxidative cyclization; oxocin ring formation

Indexed keywords

ALKALOIDS FROM MYXOMYCETES; ARCYROXOCINS; MALEIMIDES; OXIDATIVE CYCLIZATION; OXIDATIVE FORMATION; RING CLOSURES; RING FORMATION; SLIME MOLD; TOTAL SYNTHESIS;

FUNGI; METABOLITES; MOLDS; NITROGEN COMPOUNDS; PROTOZOA;

CYCLIZATION;

10 (TERT BUTOXYCARBONYL) 2 METHYL 5,10 DIHYDRO 1H PYRROLO [3',4' :4,5] OXOCINO [2,3 B:6,7,8 C',D']DIINDOLE 1,3 (2H) DIONE; 12 (BENZYLOXY) 10 (TERT BUTOXYCARBONYL) 2 METHYL 5,10 DIHYDRO 1H PYRROLO [3',4' :4,5] OXOCINO [2,3 B:6,7,8 C',D']DIINDOLE 1,3 (2H) DIONE; 12 (BENZYLOXY) 2 METHYL 5,10 DIHYDRO 1H PYRROLO [3',4' : 4,5] OXOCINO [2,3 B:6,7,8 C',D']DIINDOLE 1,3 (2H) DIONE; 12 HYDROXY 5,10 DIHYDRO 1H PYRROLO [3',4' : 4,5] OXOCINO [2,3 B:6,7,8 C',D']DIINDOLE 1,3 (2H) DIONE; 2 METHYL 5,10 DIHYDRO 1H PYRROLO [3',4' : 4,5] OXOCINO [2,3 B:6,7,8 C',D']DIINDOLE 1,3 (2H) DIONE; 3 (4 HYDROXYINDOLYL) 4 INDOLYLMALEIMIDE DERIVATIVE; 3 [1 (TERT BUTOXYCARBONYL) 4 (TETRAHYDRO 2H PYRAN 2 YLOXY) 1H INDOL 3 YL] 3 [1 (DIETHOXYMETHYL) 2 OXO 2,3 DIHYDRO 1H INDOL 3 YL] 1 METHYL 1H PYRROLE 2,5 DIONE; 3 [6 (BENZYLOXY) 1 (TERT BUTOXYCARBONYL) 1H INDOL 3 YL] 1 METHYL 4 [4 (TETRAHYDRO 2H PYRAN 2 YLOXY) 1H INDOL 3 YL] 1H PYRROLE 2,5 DIONE; 3 [6 (BENZYLOXY) 1 (TERT BUTOXYCARBONYL) 1H INDOL 3 YL] 1 METHYL 4 [4 (TETRAHYDRO 2H PYRAN 2 YLOXY) 1H INDOL 3 YL] 4 (4 HYDROXY 1H INDOL 3 YL) 1 METHYL 1H PYRROLE 2,5 DIONE; 3 BROMO 1 METHYL 4 [4 (TETRAHYDRO 2H PYRAN 2 YLOXY) 1H INDOL 3 YL] 1H PYRROLE 2,5 DIONE; 3 BROMO 4 [1 (TERT BUTOXYCARBONYL) 4 (TETRAHYDRO 2H PYRAN 2 YLOXY) 1H INDOL 3 YL] 1 METHYL 1H PYRROLE 2,5 DIONE; 4 (4 HYDROXY 1H INDOL 3 YL) 1 METHYL 3 (2 OXO 2,3 DIHYDRO 1H INDOL 3 YL) 1H PYRROLE 2,5 DIONE; 5,10 DIHYDRO 1H PYRROLO [3',4' : 4,5] OXOCINO [2,3 B:6,7,8 C',D']DIINDOLE 1,3 (2H) DIONE; 5,10 DIHYDROFURO [3',4' : 4,5] OXOCINO [2,3 B:6,7,8 C',D']DIINDOLE 1,3 DIONE; 9' METHYLSPIRO[INDOLE 3,7' PYRROLO [3',4' : 5,6]OXEPINO [4,3,2 CD]INDOLE] 2,8',10' (1H,2'H,9'H)TRIONE; ALKALOID; ARCYRIACYANIN A; ARCYRIAFLAVIN A; ARCYRIARUBIN A; ARCYROXOCIN A; ARCYROXOCIN B; MALEIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CRYSTAL STRUCTURE; CYCLIZATION; DEPROTECTION REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; MASS SPECTROMETRY; MOULD; MYXOGASTRIA; NUCLEAR MAGNETIC RESONANCE; SOLVOLYSIS;

EID: 78650881442     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1258340     Document Type: Article

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